Tissue Transglutaminase IgA

Measures IgG and IgA immune reactivity to ancient wheats, a variety of milks, alpha and beta casein, casomorphin, milk butyrophilin, other gluten cross-reactive foods, and foods that are used as gluten replacements. Detects autoimmune disorders that are associated with consumption of these food antigens due to significant cross-reactivity with human tissue, for example, the association of a-b-casein with multiple sclerosis and diabetes, or soy and aquaporin with the BBB. Developed, patented, and published by Aristo Vojdani, PhD, MSc, CLS, known as the father of functional immunology, in 2009, 2013, 2014, 2017, and 2018.

Measures IgG, IgM, and IgA antibodies against endotoxins, structural and tight junction proteins. Detects disturbance in gut flora and endotoxemia, breakdown in tight junctions (occludin, zonulin), and cytoskeletal proteins. Some or all of these contribute to leaky gut to large molecules that challenge the immune system. Leaky gut to large molecules is the gateway to autoimmunity and neuroautoimmunity via blood-brain barriers damaged by endotoxins and other factors. Developed, patented, and published by Aristo Vojdani, PhD, MSc, CLS, known as the father of functional immunology, in 2012, 2013, 2014, 2015, 2017, 2019, 2020, and 2024.

The ANA Screen detects the presence of clinically relevant circulating autoantibodies in serum.

Measures IgG and IgA immune reactivity to wheat, wheat germ agglutinin, gluten proteins, non-gluten proteins, gluteomorphins+prodynorphins, transglutaminase-2, transglutaminase-3, transglutaminase-6, and microbial transglutaminase or meat glue. Detects possible celiac disease, non-celiac gluten sensitivity, gluten ataxia, dermatitis herpetiformis, and many autoimmunities that are associated with these proteins and enzymes, including meat glue. Developed, patented, and published by Aristo Vojdani, PhD, MSc, CLS, known as the father of functional immunology, in 2004, 2008, 2011, 2013, 2016, 2017, 2020, 2023, and 2024.

Measures antibodies against 32 different pathogens that may lead to autoimmune reactivities, including oral pathogens, gut pathogens, Mycoplasma, Chlamydia, Mycobacterium avium, Candida albicans, mycotoxin-producing molds (Aspergillus, Penicillium, Stachybotrys), EBV, CMV, HHV-6, and the agent and co-infections of Lyme disease. Detects possible associations between different bacteria, viruses, parasites, yeasts, and molds with more than 80 different autoimmune diseases due to cross-reactivity and molecular mimicry. It can also be used to monitor the effectiveness of various protocols in the management of autoimmune disorders triggered by pathogens. Developed and published by Aristo Vojdani, PhD, MSc, CLS, known as the father of functional immunology, in 2006, 2009, 2014, 2015, 2018, 2021, and 2024.