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Reference Guide
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Copeptin
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Copeptin

What's 
Copeptin
?
Copeptin is a tiny protein that enters your bloodstream when you're stressed or hurt. It's part of a bigger hormone called vasopressin, which is made in a small area at the base of your brain called the hypothalamus. Vasopressin, and therefore copeptin, play an important role in keeping the right amount of water in your body. They help control how much water your kidneys take back in as they clean your blood, and how much they let go as urine. This makes copeptin a useful indicator for understanding how your body reacts to stress and keeps its water balance.
If Your Levels Are High
Elevated copeptin levels might mean that your body is dealing with more stress or injury than usual. This can be caused by various factors, such as intense exercise, emotional stress, or certain medications that impact your body's water balance. It could also mean that your body is working extra hard to keep the right amount of water, possibly due to dehydration or changes in blood volume. High copeptin levels might be linked to issues with the hypothalamus or kidneys, as these are the places where vasopressin and copeptin are made and used.
Symptoms of High Levels
Symptoms of high levels of Copeptin could include excessive thirst, frequent urination, fatigue, and unexplained weight loss.
If Your Levels are Low
Low copeptin levels might mean that your body isn't reacting to stress as well as it should. This could be due to not drinking enough water, taking certain medications, or having health issues that affect your hormone balance. Low copeptin levels could also mean that your kidneys aren't holding onto water as well as they should, which might lead to an imbalance in your body's water levels. Keep in mind that things like your diet and exercise habits can also impact your copeptin levels.
Symptoms of Low Levels
Symptoms of low levels of Copeptin may include frequent urination, excessive thirst, dry mouth, and fatigue.

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