Anti-DGP IgG

Anti-DGP IgG

What's

Anti-DGP IgG

Anti-DGP IgG, or Anti-Deamidated Gliadin Peptide Immunoglobulin G, is a special kind of antibody that your immune system creates in response to gliadin, a part of gluten. This antibody is unique because it specifically targets deamidated gliadin, a changed form of gliadin that is more likely to cause an immune reaction. The presence of Anti-DGP IgG in your blood can offer valuable information about how your body is reacting to gluten, making it an important indicator in the study of gluten-related health issues.

If Your Levels Are High

Elevated levels of Anti-DGP IgG might mean that your body is reacting to gluten in the food you eat, which is often seen in conditions like non-celiac gluten sensitivity or celiac disease. This increase could also suggest that your immune system is more sensitive and responding more strongly to substances around you, including gluten in your diet. Keep in mind that factors like eating gluten recently or taking certain medications could affect these levels.

Symptoms of High Levels

Symptoms of high levels of Anti-DGP IgG may include digestive issues such as bloating, diarrhea, or constipation, fatigue, skin rashes, and unexplained weight loss.

If Your Levels are Low

Low levels of Anti-DGP IgG might mean that your body isn't reacting strongly to a part of gluten called deamidated gliadin. This could be because you're not eating much gluten, your body naturally doesn't respond much to it, or certain medications or health issues are affecting your immune system's ability to make these antibodies. Keep in mind that having low Anti-DGP IgG levels doesn't necessarily mean you don't have any gluten-related problems, as people's immune responses can be quite different.

Symptoms of Low Levels

Symptoms of low levels of Anti-DGP IgG are typically absent, as this condition primarily indicates a lack of immune response to gluten, rather than a direct cause of physical discomfort or illness.

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See References

Test for

Celiac Disease Evaluation by Access Med Labs

Serum

This test provides a comprehensive evaluation of the antibodies that are characteristic of celiac disease. Celiac disease is also associated with selective IgA deficiency and autoimmune disorders.

Celiac & Gluten Sensitivity by Doctor's Data

Blood Spot

The Celiac & Gluten Sensitivity profile helps differentiate between celiac disease and gluten sensitivity by evaluating the serum titers of IgA and IgG for deamidated gliadin peptide, gliadin, and gluten. This is the blood spot version of the test. It is also available as a serum test.

Celiac Profile by Genova Diagnostics

Serum

The Celiac Profile is a comprehensive serologic profile that uses widely accepted immunologic biomarkers to aid in the diagnosis of Celiac disease and gluten sensitivity.

Full Immunology Panel by Genova Diagnostics

Serum

The Full Immunology Panel assesses food and inhalant allergies and sensitivities by combining the following panels: IgE Food Antibodies, IgE Inhalants, IgE Molds, IgG Food Antibodies, IgG Spices, IgG Vegetarian, and Celiac Profile.

Deamidated Gliadin Peptide IgG by Access Med Labs

Serum

This is a single-marker test measuring IgG antibodies to deamidated gliadin peptide. It is used to aid in the diagnosis of gluten-sensitive enteropathies such as celiac disease.

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High Levels

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