Anti-DGP IgA

Anti-DGP IgA

What's

Anti-DGP IgA

Anti-DGP IgA, or Anti-Deamidated Gliadin Peptide Immunoglobulin A, is a specific kind of defense protein that your body creates. It's important because it's closely connected to how your body reacts to gluten, a protein found in wheat, barley, and rye. When you eat gluten, if your body sees it as harmful, it might produce Anti-DGP IgA to help protect itself. This defense protein is often studied in relation to gluten-related health issues, making it a useful indicator in functional medicine.

If Your Levels Are High

Elevated levels of Anti-DGP IgA might mean that your body is reacting to gluten found in foods like wheat, barley, and rye. This response is often seen in conditions such as gluten sensitivity or celiac disease, where your immune system sees gluten as harmful and creates these defense proteins to protect itself. Some factors that could contribute to higher levels include eating gluten-containing foods or taking certain medications. It's important to note that some people may naturally have higher levels of Anti-DGP IgA without any negative effects. However, if levels remain consistently high, it could suggest an ongoing immune response to gluten in your diet.

Symptoms of High Levels

Symptoms of high levels of Anti-DGP IgA may include digestive issues such as bloating, diarrhea, or constipation, fatigue, weight loss, and skin rashes. Some people may also experience joint pain or headaches.

If Your Levels are Low

Low levels of Anti-DGP IgA might mean that your body isn't reacting much to gluten, which could suggest a lower chance of having problems related to gluten. This could be because of different reasons, like eating a gluten-free diet, taking certain medicines, or just because everyone's immune system is unique. On the other hand, it's also possible that your immune system isn't making these antibodies well, which might be connected to your overall immune health. Keep in mind that this is just one part of the bigger picture and should be looked at along with your overall health and lifestyle.

Symptoms of Low Levels

Symptoms of low levels of Anti-DGP IgA are typically absent, as this condition often does not present noticeable signs or discomfort.

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See References

Test for

Celiac Disease Evaluation by Access Med Labs

Serum

This test provides a comprehensive evaluation of the antibodies that are characteristic of celiac disease. Celiac disease is also associated with selective IgA deficiency and autoimmune disorders.

Celiac Profile by Genova Diagnostics

Serum

The Celiac Profile is a comprehensive serologic profile that uses widely accepted immunologic biomarkers to aid in the diagnosis of Celiac disease and gluten sensitivity.

Full Immunology Panel by Genova Diagnostics

Serum

The Full Immunology Panel assesses food and inhalant allergies and sensitivities by combining the following panels: IgE Food Antibodies, IgE Inhalants, IgE Molds, IgG Food Antibodies, IgG Spices, IgG Vegetarian, and Celiac Profile.

Celiac & Gluten Sensitivity by Doctor's Data

Blood Spot

The Celiac & Gluten Sensitivity profile helps differentiate between celiac disease and gluten sensitivity by evaluating the serum titers of IgA and IgG for deamidated gliadin peptide, gliadin, and gluten. This is the blood spot version of the test. It is also available as a serum test.

Deamidated Gliadin Peptide IgA by Access Med Labs

Serum

This is a single-marker test measuring IgA antibodies to deamidated gliadin peptide. It is used to aid in the diagnosis of gluten-sensitive enteropathies such as celiac disease.

CONTENTS

What is it?

High Levels

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