Lyme Disease: Diagnostic Challenges & Insights

Tick-borne diseases are an increasing public health concern in the United States and worldwide. Early detection of Lyme disease is critical, as timely intervention may improve patient outcomes. The Centers for Disease Control and Prevention (CDC) recommends a two-step serological testing process: Step 1: Enzyme-linked immunosorbent assay (ELISA), followed by Step 2: Western blot testing to confirm the presence of antibodies against Borrelia burgdorferi and its subspecies.

Despite these guidelines, variations in laboratory methodologies can lead to inconsistencies in test results, creating challenges for both practitioners and patients. Understanding the principles of accurate testing is essential for informed decision-making. In this session, Dr. Vojdani, drawing on decades of research in immunological laboratories, will discuss the importance of accurate diagnostic approaches for Lyme disease.

Key Learning Objectives:

• Explore the principles of laboratory testing for Lyme disease.
• Compare various diagnostic methodologies, including established approaches such as ELISA and Western blot.
• Examine potential limitations of alternative testing methods and their implications for clinical decision-making.
• Discuss the role of CD57-positive immune cells in immune function and why they should not be used as a diagnostic marker for Lyme disease.

Join us for this informative session as Dr. Vojdani shares valuable insights on Lyme disease diagnostics. Register now to secure your spot!

‍