Tumor Necrosis Factor Alpha

Elevated TNF-a levels might mean that your body is dealing with more inflammation or infection than usual. This protein is like a little soldier in your immune system, so when it's higher, it could mean your body is working extra hard to keep you safe. Things like stress, not-so-great food choices, not getting enough sleep, or being around harmful stuff in your environment might make your TNF-a levels go up. Some medications could also affect how much TNF-a your body makes. High TNF-a levels could be linked to conditions like long-lasting inflammation, problems with your immune system attacking your own body, or issues with how your body processes sugar and fat.

Symptoms of high levels of TNF-a may include fatigue, joint pain, skin problems, sleep disturbances, mood changes, and unexplained weight changes.

Having low levels of TNF-a might mean that your immune system isn't as strong as it should be, making it harder for your body to fight off infections and illnesses. This important protein is like a tiny soldier in your body's defense team, and when there's not enough of it, you could be more vulnerable to getting sick. Some medications, like anti-inflammatory drugs or drugs that suppress the immune system, might be a reason for lower TNF-a levels. Also, certain health conditions, such as chronic fatigue syndrome or some autoimmune disorders, could be linked to having less TNF-a in your body. Keep in mind that this protein also helps with mood and sleep, so having low levels might affect those areas too.

Symptoms of low levels of TNF-a might include frequent infections, prolonged recovery times from illness, fatigue, mood swings, and irregular sleep patterns.