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Reference Guide
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TSI
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Thyroid-Stimulating Immunoglobulin

What's 
TSI
?
Thyroid-Stimulating Immunoglobulin (TSI) is a special kind of antibody made by your immune system. Unlike most antibodies that protect your body from harmful substances, TSI targets your own thyroid gland, specifically the parts that respond to Thyroid Stimulating Hormone (TSH). When TSI connects with these parts, it acts like TSH, encouraging the thyroid to create and release thyroid hormones. This interaction has a significant impact on how well your thyroid works, which is in charge of controlling your body's metabolism and energy use.
If Your Levels Are High
Elevated TSI levels might mean that your immune system is working overtime and mistakenly targeting your thyroid gland. This could be due to various reasons like stress, poor diet, lack of sleep, or even certain medications that can throw off your immune system's balance. It might also point to an underlying condition, such as Graves' disease, where your immune system attacks your own body's cells. This can lead to an overactive thyroid gland, which produces too many thyroid hormones and affects your body's metabolism and energy use.
Symptoms of High Levels
Symptoms of high levels of TSI could include rapid heart rate, weight loss, increased appetite, nervousness, restlessness, inability to concentrate, and frequent bowel movements.
If Your Levels are Low
A low TSI level means that your body might not be making enough of these special antibodies to properly stimulate your thyroid gland. This can lead to a decrease in the production and release of important thyroid hormones, which help control your body's energy use and metabolism. There are several reasons this could happen, such as taking certain medications, not getting enough nutrients, dealing with chronic stress, or having an autoimmune disorder. It's also possible that something is suppressing your immune system, which could affect how much TSI your body produces.
Symptoms of Low Levels
Symptoms of low levels of TSI may not be immediately noticeable, but over time, they could include fatigue, weight gain, cold intolerance, dry skin, and constipation.

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Thyroid-Stimulating Immunoglobulin

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