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Reference Guide
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MTHFR
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MTHFR

What's 
MTHFR
?
MTHFR, or Methylenetetrahydrofolate Reductase, is an essential gene in your body. Think of it as a tiny factory that creates an enzyme needed for a complex process called methylation. Methylation is like a busy highway inside your cells, happening billions of times every second. It helps your body build and fix DNA, generate energy, cleanse itself, and manage inflammation, among other tasks. The MTHFR gene is also in charge of turning folate, a kind of B vitamin, into a form that your body can use. So, in short, MTHFR plays a crucial role in maintaining your body's overall health and well-being.
If Your Levels Are High
Elevated MTHFR levels might mean that your body is making more of the MTHFR enzyme than usual, which could be due to factors like your genes, the food you eat, or certain medications you're taking. This enzyme helps change folate, a type of B vitamin, into a form your body can use, so having too much of it could lead to an excess of active folate. This can impact various functions in your body, such as creating and repairing DNA, making energy, getting rid of toxins, and controlling inflammation. It's also possible that high MTHFR levels could be a sign of an issue with your body's methylation process, which might be related to specific conditions or influenced by medications like antacids, anti-inflammatory drugs, or certain supplements.
Symptoms of High Levels
Symptoms of high levels of MTHFR could potentially be non-specific and vary widely among individuals. They might include fatigue, mood changes, or difficulties with concentration and memory.
If Your Levels are Low
Having low levels of MTHFR might mean that your body isn't making enough of the MTHFR enzyme, which is really important for a process called methylation. Methylation is like a super busy highway inside your cells, taking care of many tasks like fixing DNA, creating energy, cleaning your body, and keeping inflammation in check. The MTHFR gene also helps change folate, a kind of B vitamin, into a form your body can use. If this change isn't happening well, it could lead to not having enough active folate. Things like what you eat, stress, and certain medications (like some antacids or anti-inflammatory drugs) could affect how well the MTHFR gene works. So, low MTHFR levels could be related to these factors or other health issues that impact methylation and folate conversion.
Symptoms of Low Levels
Symptoms of low levels of MTHFR could include fatigue, mood swings, cardiovascular issues, and difficulties with memory or concentration.

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