Complement C3a

High levels of Complement C3a in your blood could indicate that your immune system is working overtime, suggesting an ongoing infection or an autoimmune condition where your body mistakenly attacks its own cells. Certain medications, like immunosuppressants, can also affect the levels of Complement C3a. Conditions such as Lupus, Rheumatoid Arthritis, or certain types of kidney disease like Membranoproliferative Glomerulonephritis, are known to cause an increase in Complement C3a levels. Additionally, high levels could be a response to a severe allergic reaction or a result of a chronic inflammatory disease. It's important to note that while high levels of Complement C3a can indicate these conditions, they are not definitive and further testing would be needed for a precise diagnosis.

Symptoms of high levels of Complement C3a could include fatigue, joint pain, skin rashes, unexplained weight loss, or frequent infections.

Low levels of Complement C3a in your blood could suggest that your immune system isn't as active as it should be. This could be due to a variety of reasons. For instance, you might have a condition that weakens your immune system, such as an autoimmune disease where your body mistakenly attacks its own cells, or a genetic disorder that affects your body's ability to produce this substance. Certain medications, like immunosuppressants used to prevent organ rejection after a transplant, or corticosteroids used to reduce inflammation, can also lower your Complement C3a levels. Additionally, chronic stress or poor nutrition can negatively impact your immune system's functionality. Therefore, low Complement C3a levels could be a sign that your body's defense system isn't fully prepared to fight off infections or diseases.

Symptoms of low levels of Complement C3a may not be easily noticeable, as they can be quite general and similar to symptoms of other conditions. They could include frequent infections, prolonged recovery from illnesses, fatigue, and unexplained weight loss.