Anti-VCA IgG is a specific kind of antibody that your body creates to fight off the Epstein-Barr Virus (EBV), which is known for causing infectious mononucleosis or "mono." The term "VCA" stands for "viral capsid antigen," which is a part of the virus that activates your immune response. When your body comes into contact with EBV, it produces Anti-VCA IgG antibodies to help combat the virus. The presence of these antibodies in your blood can give important information about your immune system's previous encounters with EBV.
If Your Levels Are High
High levels of Anti-VCA IgG antibodies in your blood might mean that your body has been actively fighting the Epstein-Barr Virus (EBV), which can cause mono. This could be due to a new infection, or it might be because an old infection has become active again. Sometimes, stress or a weak immune system can cause the virus to reactivate. Certain medications, like immune-suppressing drugs, might also lead to higher levels of these antibodies. Keep in mind that having high levels of Anti-VCA IgG can also be a normal part of your body's long-lasting response to EBV, and these antibodies can stay in your blood for many years after you first get infected.
Symptoms of High Levels
Symptoms of high levels of Anti-VCA IgG may not be distinct, as they could mirror general signs of an active or recent infection, such as fatigue, fever, sore throat, swollen lymph nodes, and a general feeling of being unwell.
If Your Levels are Low
Low levels of Anti-VCA IgG might mean that your body hasn't come across the Epstein-Barr Virus (EBV) before, possibly because you haven't been exposed to it or your immune system didn't react strongly to a past infection. It could also mean that your body successfully fought off the infection and the antibody levels have gone down over time. Certain medications, like those that suppress the immune system, could also affect the production of these antibodies.
Symptoms of Low Levels
Symptoms of low levels of Anti-VCA IgG are typically non-existent, as this simply reflects a lack of previous exposure to the Epstein-Barr Virus or a successful clearance of the infection.
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The Epstein-Barr Evaluation assesses several antibodies to the Epstein-Barr virus (EBV). It is performed to confirm active, past, or indeterminate infection for EBV-associated infectious mononucleosis.
Epstein-Barr Virus (EBV) Panel by Immunosciences Lab, Inc.
Serum
EBV contributes to more than 30 autoimmune disorders. Detection of IgG or IgM antibodies to various EBV antigens indicates either past infection, primary reactivation, or re-infection with Epstein-Barr Virus or Herpes Type 4.
Epstein-Barr Viral Capsid Ag, IgG by Access Med Labs
Serum
This test measures IgG antibodies to EBV viral capsid antigen (VCA). It is used to aid in the diagnosis of infectious mononucleosis.
Long COVID Panel by Immunosciences Lab, Inc.
Serum
The Long COVID Panel is used to detect three major viruses (EBV, HHV-6, and SARS-CoV-2) associated with long COVID and autoimmunity. It has been found that increased levels of antibodies against EBV and HHV-6 correlate with the severity of long COVID.
Epstein-Barr Evaluation by Access Labcorp Draw
Serum
The Epstein-Barr Evaluation assesses several antibodies to the Epstein-Barr virus (EBV). It is performed to confirm active, past, or indeterminate infection for EBV-associated infectious mononucleosis.