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Reference Guide
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Anti-dsDNA
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Anti-dsDNA
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Anti-Double-Stranded DNA

What's 
Anti-dsDNA
?
Anti-Double-Stranded DNA (Anti-dsDNA) is a specific kind of antibody made by your body's defense system. These antibodies are special because they target a particular form of DNA - double-stranded DNA - which is the normal structure of your genetic material. In a healthy immune system, these antibodies are usually not present or found in very low amounts. However, their presence can be an important sign of certain health issues. The Anti-dsDNA test is a method used to find these antibodies in your blood, giving valuable information about your immune system's activity.
If Your Levels Are High
If your Anti-dsDNA levels are higher than normal, it means your immune system is working harder than usual. This can happen for various reasons, such as fighting off an infection or reacting to certain medications like antibiotics or blood pressure drugs. Sometimes, high Anti-dsDNA levels can be linked to autoimmune diseases, where your immune system mistakenly attacks your own body. One example is systemic lupus erythematosus (SLE), a long-term condition that can affect different parts of your body. Keep in mind that things like stress and a poor diet can also impact your immune system and lead to higher Anti-dsDNA levels.
Symptoms of High Levels
Symptoms of high levels of Anti-dsDNA could include fatigue, joint pain, skin rashes, and unexplained fever. In some cases, individuals may experience no symptoms at all.
If Your Levels are Low
Low levels of Anti-dsDNA antibodies might mean that your immune system isn't producing these antibodies in large amounts, which is actually normal for most people. In a healthy immune system, these antibodies are usually absent or present in small quantities. It's possible that certain medications or treatments could be affecting the production of these antibodies, but it's important to remember that low levels aren't necessarily a sign of a health problem. Anti-dsDNA levels can change and vary between individuals, so having low levels might just be normal for you.
Symptoms of Low Levels
Symptoms of low levels of Anti-dsDNA are typically absent, as this is often a sign of a healthy, well-functioning immune system.

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