A Root Cause Medicine Approach
|
August 2, 2021

How A Lymphocyte MAP Tests Your Immune Strength

Written By
Dr. Shawn Greenan DACM, CFMP®
Medically Reviewed by
Updated On
January 14, 2025

We are so excited to do a feature article on Cyrex Laboratories' newest test addition, THE LYMPHOCYTE MAP™. We had a great conversation with Michelle Clark, Vice President of Worldwide Sales, about Cyrex’s latest test and all the features it offers. So, without further ado, let’s get started.

Hi Michelle! Great to chat with you. Let’s dive in - Can you give us a brief introduction to this test, including its name?

The THE LYMPHOCYTE MAP™ test is based on a culmination of 10 years of research and development by Aristo Vojdani, Ph.D., Chief Scientific Advisor at Cyrex. “This test offers a detailed picture of T-lymphocyte status,” according to Dr. Vojdani.

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How does this test work?

The Lymphocyte MAP measures various aspects of the immune system at the cellular level by identifying 29 key lymphocyte biomarkers and determinants, including Th1, Th2, CD4, CD8, Treg, Th17, and the family of NK cells. Numbers, ratios, percentages, and activity (NRPA) are provided and organized into one of thirteen immunotypes.

What are the key features of this test?

  • Thirteen immunotypes designed to capture and highlight important immune trends revealed due to the comprehensive number of determinants and biomarkers tested.
  • T-helper-1 or T-helper-2 Dominance (Immunotypes 6 and 7) Includes the Cyrex Fluorescence-Activated Cell Test (FACT™), a proprietary process, used to classify Th1/Th2 balance, based on the specific clusters of differentiation (CD markers) on the surface membranes of Th1 or Th2 cells, and NOT on the measurement of Th1/Th2-associated cytokine levels in the blood, commonly used by other laboratories.
  • T-helper-17 Dominance (Immunotype 9) Includes the Cyrex FACT™, a proprietary process based on direct measurement of the CD markers on the surface membranes of the cells, and NOT by measuring IL-17 levels in the blood. These features aim to provide a detailed picture of T-helper cell status.
  • The most comprehensive immunophenotyping panel offered on the market, creating a broad picture of immune status.

Wow, that sounds technical and cool! What are the main conditions practitioners are using this test for?

The Lymphocyte MAP provides insights into various immune-related conditions. It is used in a wide array of cases, from individuals seeking to maintain a healthy lifestyle and aging to those with previously diagnosed autoimmune conditions or recent exposure to certain infections. The results can help plan and monitor a health regimen, with the goal of supporting immune balance.

What technology do you use at your lab? Can you explain how the technology works?

Flow cytometry is a technique for cell counting and measurement of different properties of a cell. The Cyrex Fluorescent Activated Cell Test (FACT-TM) identifies Clusters of Differentiation (CD) markers using proprietary fluorescently labeled monoclonal antibodies to distinguish different cell populations accurately.

Wonderful! Thank you for taking the time to speak with us and introducing us to your new test, The Lymphocyte Map.

To learn more about The Lymphocyte Map, visit the Rupa Health Lab Test Catalog and type in The Lymphocyte Map into the search option.

If you’re a Rupa Practitioner, you can also view the cost of each test.

Not yet a Rupa Practitioner? It’s free to sign up here!

The information in this article is designed for educational purposes only and is not intended to be a substitute for informed medical advice or care. This information should not be used to diagnose or treat any health problems or illnesses without consulting a doctor. Consult with a health care practitioner before relying on any information in this article or on this website.

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