Title
Subscribe to the Magazine for free
Subscribe for free to keep reading! If you are already subscribed, enter your email address to log back in.
Thanks for subscribing!
Oops! Something went wrong while submitting the form.
Are you a healthcare practitioner?
Thanks for subscribing!
Oops! Something went wrong while submitting the form.

Is The DUTCH Test Legitimate?

Why This Was Updated?

Our specialists regularly review advancements in health and wellness, ensuring our articles are updated with the newest information as it becomes accessible.
Medically Reviewed by

When it comes to hormone health, there's a lot to consider. Many people struggle with hormone imbalances that affect their energy levels, mood, weight, and even sleep. Understanding and managing these imbalances may contribute to overall well-being, but identifying the underlying factors can be challenging.

The DUTCH test has become a popular tool in functional medicine for evaluating hormone-related patterns using dried urine samples. But is it an effective tool for supporting hormone health, or should you approach it with caution?

In this article, we'll explore the ins and outs of the DUTCH test, from its scientific backing to its place in functional medicine. By the end, you'll have a clearer picture of whether this test is worth considering for yourself or your patients.

Sign Up to Order a DUTCH Test 🧪

[signup]

What is the DUTCH Test?

The DUTCH test stands for Dried Urine Test for Comprehensive Hormones. As the name suggests, it involves collecting urine samples to measure various hormones and their metabolites. 

Unlike traditional hormone tests that use blood or saliva, the DUTCH test offers a broader perspective on hormone metabolism by examining hormone breakdown products. This may provide additional information about how the body processes these hormones.

Hormones and Metabolites Measured

The DUTCH test evaluates a range of hormones and their metabolites, including:

Why Use the DUTCH Test?

People commonly turn to the DUTCH test for a variety of reasons. It's beneficial in identifying hormone imbalances that can affect adrenal function, sleep, mood, and metabolism. Doctors often recommend the DUTCH test for patients struggling with:

The DUTCH test provides information about how the body may be metabolizing hormones, offering practitioners insights into hormone patterns and the ways the body might be using and eliminating these hormones.

Understanding Lab Test Accreditation

When evaluating any lab test, including the DUTCH test, it's crucial to understand the role of lab accreditation. Accreditation ensures that a lab meets specific standards for accuracy, reliability, and quality control. For a test to be considered legitimate, the lab that conducts it should be accredited by a recognized body.

Key Accrediting Bodies

Several key organizations oversee lab standards:

Why Accreditation Matters

Accreditation assures that a lab adheres to strict guidelines and undergoes regular audits to maintain high testing standards. This reduces the chances of inaccurate results due to poor lab practices and ensures that test outcomes are reliable for clinical use.

DUTCH Test Accreditation and Certification

The legitimacy of the DUTCH test isn't just about the test itself but also about the labs that run it. Precision Analytical, the company behind the DUTCH test, operates under stringent guidelines and holds certifications from reputable bodies. It is CLIA-certified, which means it meets federal requirements for laboratory testing accuracy and reliability.

Compared to other hormone tests, such as those conducted by saliva or blood, the DUTCH test labs have demonstrated high standards in handling samples, ensuring accurate and trustworthy results. This gives practitioners more confidence in using the test as a comprehensive approach to hormone health.

Scientific Validity of the DUTCH Test

Any lab test must be backed by solid science to be considered legitimate. So, what does the research say about the DUTCH test?

Supporting Studies

Several peer-reviewed studies suggest that the DUTCH test may offer useful information, particularly in measuring cortisol metabolism and adrenal patterns. Research has shown that dried urine testing provides a reliable snapshot of cortisol patterns over 24 hours, offering insights into adrenal health that other methods may miss.

Regarding sex hormones like estrogen, the DUTCH test allows practitioners to assess how the body breaks down estrogen into different metabolites. This can be particularly important for understanding risks related to hormone-driven conditions like breast cancer, as some estrogen metabolites are more harmful than others.

Criticisms and Limitations

However, like any medical test, the DUTCH test has its critics. Some researchers argue that because it's relatively new compared to traditional blood or saliva testing, there isn't as much long-term research available. 

Others point out that while it's excellent for measuring hormone metabolites, it might not always be the best choice for measuring hormones at specific points in time, as blood tests do.

Still, the growing body of evidence suggests that the DUTCH test provides valuable information that can complement other forms of hormone testing.

Comparing the DUTCH Test with Other Hormone Tests

To truly assess the DUTCH test's legitimacy, comparing it to other common hormone testing methods, such as blood and saliva tests, is essential.

Blood Tests

Blood tests are the most common way to measure hormones like estrogen, testosterone, and cortisol. They offer a quick snapshot of hormone levels at a specific time, making them useful for detecting acute imbalances. 

However, they don't explain how hormones are metabolized over time or how they fluctuate throughout the day.

Pros:

  • Widely used and well-studied
  • Standardized and covered by most insurance plans

Cons:

  • Only measures hormones at a single point in time
  • Can miss daily fluctuations and how hormones are processed

Saliva Tests

Saliva testing is often used to measure free cortisol levels and other hormones. It's convenient and non-invasive, but like blood tests, it only measures hormone levels at specific points in the day.

Pros:

  • Non-invasive and easy to collect
  • It helps measure free hormones

Cons:

  • Limited to certain hormones like cortisol
  • It doesn't provide information on hormone metabolism

How the DUTCH Test Stands Out

The DUTCH test stands out because it offers a more comprehensive view of hormone health. Measuring hormone metabolites and their patterns over 24 hours provides deeper insights into how the body processes hormones. This makes it particularly valuable for complex cases involving adrenal fatigue, hormone imbalance, or unexplained symptoms.

Sign Up to Order a DUTCH Test 🧪

Case Study: Using the DUTCH Test in Clinical Practice

The DUTCH test has been a valuable tool for many functional medicine practitioners, including in cases like Julie's, a 32-year-old woman struggling with infertility, severe PMS, endometriosis, and Hashimoto's thyroiditis

After over a year of unsuccessful attempts to conceive, including three rounds of IVF, she sought help for her worsening symptoms of painful periods, fatigue, mood swings, and bloating. 

Despite being treated with thyroid medication, traditional hormone testing didn't provide clear answers. To dig deeper, her practitioner ordered the DUTCH test, which revealed significant estrogen dominance, low progesterone levels, and high levels of inflammatory estrogen metabolites

Additionally, it showed elevated cortisol, contributing to both her fertility issues and PMS. These findings, alongside her genetic variations affecting estrogen metabolism, provided additional insights that may not have been revealed by other tests.

Using the findings from her DUTCH test, her practitioner crafted a personalized plan, including:

Julie experienced improved energy, less pain, and more regular cycles within months. After completing treatment, she conceived naturally and had a healthy pregnancy, showcasing the power of personalized hormone testing.

Making an Informed Decision

If you're considering hormone testing, making an informed decision is essential. The DUTCH test offers a unique and comprehensive look at hormone metabolism, but it's not the only option. Here are some factors to keep in mind:

  • Consult a healthcare provider: A professional can help determine which test suits your situation.
  • Understand your symptoms: Chronic fatigue, mood swings, or menstrual irregularities could prompt a discussion with your healthcare provider about the need for more in-depth hormone testing.
  • Ask about accreditation: Ensure that the lab conducting the test is appropriately accredited and follows high standards.

Key Questions to Ask Your Provider

  • Is the DUTCH test the best option for my symptoms?
  • How does this test compare to blood or saliva tests for my condition?
  • Will the results help guide treatment in a meaningful way?

Sign Up to Order a DUTCH Test 🧪

[signup]

Key Takeaways

  • The DUTCH test may be a helpful tool for gaining insights into hormone metabolism, particularly for cortisol, estrogen, and progesterone.
  • The labs that run the DUTCH test are accredited, ensuring accuracy and reliability.
  • Compared to blood and saliva tests, the DUTCH test offers a more comprehensive look at how hormones are processed throughout the day.
  • While research supports it, it's essential to consult with a healthcare provider to determine if the DUTCH test is right for you.
  • The DUTCH test can be a valuable resource for understanding hormone imbalances, but it's one piece of a larger puzzle in assessing and optimizing hormone health.
The information provided is not intended to be a substitute for professional medical advice. Always consult with your doctor or other qualified healthcare provider before taking any dietary supplement or making any changes to your diet or exercise routine.
Learn More
No items found.

Lab Tests in This Article

No lab tests!

Afari, N., & Buchwald, D. (2003). Chronic Fatigue Syndrome: A Review. American Journal of Psychiatry, 160(2), 221–236. https://doi.org/10.1176/appi.ajp.160.2.221

Anderson, S. (2022, July 18). What Is Adrenal Fatigue? Is It A Real Condition? Rupa Health. https://www.rupahealth.com/post/wired-but-tired-this-isnt-a-normal-part-of-aging

Bertagna, B. (2024, January 8). Melatonin for sleep: Unlocking the power of this hormone for restful nights. Rupa Health. https://www.rupahealth.com/post/melatonin-for-sleep-unlocking-the-power-of-this-hormone-for-restful-nights

Broekmans, F. J., Kwee, J., Hendriks, D. J., Mol, B. W., & Lambalk, C. B. (2006). A systematic review of tests predicting ovarian reserve and IVF outcome. Human Reproduction Update, 12(6), 685–718. https://doi.org/10.1093/humupd/dml034

Bryant, A. (2024, September 2). How to Have a Good Night Sleep: Top Proven Strategies for Better Rest. Rupa Health. https://www.rupahealth.com/post/how-to-have-a-good-night-sleep-top-proven-strategies-for-better-rest

Chen, X., Sykora, M. D., Jackson, T. W., & Elayan, S. (2018). What about Mood Swings. Companion of the the Web Conference 2018 on the Web Conference 2018 - WWW '18. https://doi.org/10.1145/3184558.3191624

Christie, J. (2022a, March 25). The Most Common Causes Of Infertility In Men and Women. Rupa Health. https://www.rupahealth.com/post/a-functional-medicine-approach-to-infertility

Christie, J. (2022b, April 7). 5 Common Root Causes Of Endometriosis And How To Treat Them. Rupa Health. https://www.rupahealth.com/post/a-functional-medicine-approach-to-endometriosis

Christie, J. (2022c, August 23). Weight Gain, Low Libido, And Headaches Are Signs You Aren't Metabolizing This Hormone Properly. Rupa Health. https://www.rupahealth.com/post/how-to-know-if-your-body-is-metabolizing-estrogen-properly

Christie, J. (2023, January 19). An Integrative Medicine Approach to Perimenopause. Rupa Health. https://www.rupahealth.com/post/an-integrative-approach-to-perimenopause

Clinical Laboratory Improvement Amendments (CLIA) | CMS. (n.d.). Www.cms.gov. https://www.cms.gov/medicare/quality/clinical-laboratory-improvement-amendments

Cloyd, J. (2023a, February 16). A functional medicine protocol for estrogen dominance. Rupa Health. https://www.rupahealth.com/post/a-functional-medicine-protocol-for-estrogen-dominance

Cloyd, J. (2023b, March 7). An integrative medicine approach to fatigue. Rupa Health. https://www.rupahealth.com/post/an-integrative-medicine-approach-to-fatigue

Cloyd, J. (2023c, August 10). Top Labs To Run Bi-Annually On Your Patients Who Suffer From Premenstrual Syndrome (PMS). Rupa Health. https://www.rupahealth.com/post/top-labs-to-run-bi-annually-on-your-patients-who-suffer-from-premenstrual-syndrome-pms

Cloyd, J. (2024a, February 27). Sleep Requirements by Age Group & Why It's Important. Rupa Health. https://www.rupahealth.com/post/sleep-requirements-by-age-group-why-its-important

Cloyd, J. (2024b, March 7). The Best Supplements for Sustained Energy Boosts. Rupa Health. https://www.rupahealth.com/post/the-best-supplements-for-sustained-energy-boosts

Cloyd, J. (2024c, June 3). Cortisol Dysregulation: Causes, Symptoms & Management. Rupa Health. https://www.rupahealth.com/post/cortisol-dysregulation

Cloyd, K. (2024, January 10). Calcium-D-Glucarate's Effectiveness in Estrogen Balance: An Integrative Endocrine View. Rupa Health. https://www.rupahealth.com/post/calcium-d-glucarates-effectiveness-in-estrogen-balance-an-integrative-endocrine-view

Cortisol. (n.d.). Rupa Health. https://www.rupahealth.com/biomarkers/cortisol

Dalessandri, K. M., Firestone, G. L., Fitch, M. D., Bradlow, H. L., & Bjeldanes, L. F. (2004). Pilot Study: Effect of 3,3′-Diindolylmethane Supplements on Urinary Hormone Metabolites in Postmenopausal Women With a History of Early-Stage Breast Cancer. Nutrition and Cancer, 50(2), 161–167. https://doi.org/10.1207/s15327914nc5002_5

DeCesaris, L. (2023a, January 25). How to Support a Healthy Menstrual Cycle. Rupa Health. https://www.rupahealth.com/post/how-to-support-a-healthy-menstrual-cycle

DeCesaris, L. (2023b, December 12). Elevating Mood with Nutraceuticals: A Functional Medicine Perspective. Rupa Health. https://www.rupahealth.com/post/elevating-mood-with-nutraceuticals-a-functional-medicine-perspective

DHEA-S. (n.d.). Rupa Health. https://www.rupahealth.com/biomarkers/dhea-s

DUTCH Test – Advanced Hormone Testing. (2019). Dutchtest.com. https://dutchtest.com/

EKINS, R. (1990). Measurement of Free Hormones in Blood. Endocrine Reviews, 11(1), 5–46. https://doi.org/10.1210/edrv-11-1-5

Estradiol. (n.d.). Rupa Health. https://www.rupahealth.com/biomarkers/e2

Foster, C., & Al-Zubeidi, H. (2018). Menstrual Irregularities. Pediatric Annals, 47(1), e23–e28. https://doi.org/10.3928/19382359-20171219-01

Gordon, J. L., Girdler, S. S., Meltzer-Brody, S. E., Stika, C. S., Thurston, R. C., Clark, C. T., Prairie, B. A., Moses-Kolko, E., Joffe, H., & Wisner, K. L. (2015). Ovarian Hormone Fluctuation, Neurosteroids, and HPA Axis Dysregulation in Perimenopausal Depression: A Novel Heuristic Model. American Journal of Psychiatry, 172(3), 227–236. https://doi.org/10.1176/appi.ajp.2014.14070918

GröschlM. (2008). Current Status of Salivary Hormone Analysis. Clinical Chemistry, 54(11), 1759–1769. https://doi.org/10.1373/clinchem.2008.108910

Heires, M. (2008). The International Organization for Standardization (ISO). New Political Economy, 13(3), 357–367. https://doi.org/10.1080/13563460802302693

Henry, E. (2022, January 4). How To Reverse Weight Gain And Slowed Metabolism. Rupa Health. https://www.rupahealth.com/post/a-functional-medicine-approach-to-slow-metabolism-middle-age

Kerslake, R. (2022, March 14). What the DUTCH Test Can (and Can't) Do for You. Getmegiddy.com. https://getmegiddy.com/DUTCH-test

Köhrle, J. (2019). The Colorful Diversity of Thyroid Hormone Metabolites. European Thyroid Journal, 8(3), 115–129. https://doi.org/10.1159/000497141

Kresge, K. (2023, February 21). An Integrative Medicine Approach to Depression. Rupa Health. https://www.rupahealth.com/post/an-integrative-medicine-approach-to-depression

LoBisco, S. (2022, November 16). 7 Natural Treatments For Low Progesterone. Rupa Health. https://www.rupahealth.com/post/progesterone-imbalance-signs-treatments

Maholy, N. (2023, February 17). A functional medicine approach to anxiety: Testing, nutrition, & supplements. Rupa Health. https://www.rupahealth.com/post/a-functional-medicine-approach-to-anxiety

Malani, S. (2023, April 17). An Integrative Medicine Approach to Breast Cancer Prevention. Rupa Health. https://www.rupahealth.com/post/an-integrative-medicine-approach-to-breast-cancer-prevention

Mueller, A. (2022, January 20). Julie Was Finally Able To Get Pregnant After Addressing This Hormone Imbalance. Rupa Health. https://www.rupahealth.com/post/a-functional-medicine-approach-to-infertility-a-case-study

Newman, M., & Curran, D. A. (2021). Reliability of a dried urine test for comprehensive assessment of urine hormones and metabolites. BMC Chemistry, 15(1). https://doi.org/10.1186/s13065-021-00744-3

NEWMAN, M. S. Clinical Validation of DUTCH Test.

Preston, J. (2023, August 1). The Role of Integrative Nutrition in Supporting Pregnancy. Rupa Health. https://www.rupahealth.com/post/the-role-of-integrative-nutrition-in-supporting-pregnancy

Progesterone. (n.d.). Rupa Health. https://www.rupahealth.com/biomarkers/progesterone

Pruessner, J. C., Wolf, O. T., Hellhammer, D. H., Buske-Kirschbaum, A., von Auer, K., Jobst, S., Kaspers, F., & Kirschbaum, C. (1997). Free Cortisol Levels after Awakening: A Reliable Biological Marker for the Assessment of Adrenocortical Activity. Life Sciences, 61(26), 2539–2549. https://doi.org/10.1016/s0024-3205(97)01008-4

Rabinovitch, A. (2002). The College of American Pathologists laboratory accreditation program. Accreditation and Quality Assurance, 7(11), 473–476. https://doi.org/10.1007/s00769-002-0537-0

Redirecting. (2024). Google.com. https://www.google.com/url?q=https://www.rupahealth.com/biomarkers/cortisol&sa=D&source=docs&ust=1727557008034522&usg=AOvVaw2SenASBslJ4AKW9N2YwjGc

Saluk-Juszczak, J. (2010). A comparative study of antioxidative activity of calcium-D-glucarate, sodium-D-gluconate and D-glucono-1,4-lactone in a human blood platelet model. Platelets, 21(8), 632–640. https://doi.org/10.3109/09537104.2010.512210

Sweetnich, J. (2023a, February 15). How to Support Optimal Liver Estrogen Detoxification. Rupa Health. https://www.rupahealth.com/post/how-the-liver-affects-female-hormones

Sweetnich, J. (2023b, February 21). Top Gut Healing Supplements Used By Integrative Medicine Practitioners. Rupa Health. https://www.rupahealth.com/post/top-gut-healing-supplements-used-by-integrative-medicine-practitioners

Sweetnich, J. (2023c, February 28). Testosterone Testing 101. Rupa Health. https://www.rupahealth.com/post/testosterone-testing-101

Sweetnich, J. (2023d, April 20). Which DUTCH Test Is Best For Your Patients? Rupa Health. https://www.rupahealth.com/post/dutch-complete-vs-dutch-plus-vs-dutch-cycle-map-a-guide

Sweetnich, J. (2023e, June 12). Integrative Treatment Options for Adrenal Disorders: Specialty Testing, Nutrition, Supplements. Rupa Health. https://www.rupahealth.com/post/integrative-treatment-options-for-adrenal-disorders-specialty-testing-nutrition-supplements

Sweetnich, J. (2023f, June 28). Top Functional Medicine Lab Tests That Can Help Individualize Treatment for Patients With Hashimoto's Thyroiditis. Rupa Health. https://www.rupahealth.com/post/functional-medicine-labs-that-can-help-individualize-treatment-for-patients-with-hashimotos-thyroiditis

Teeter, L. A. (2023a, April 4). Functional Nutrition Strategies For Weight Management and Metabolic Health. Rupa Health. https://www.rupahealth.com/post/functional-nutrition-strategies-for-weight-management-and-metabolic-health

Teeter, L. A. (2023b, April 13). Using functional nutrition to address hormone imbalances. Rupa Health. https://www.rupahealth.com/post/using-functional-nutrition-to-address-hormone-imbalances

Testosterone. (n.d.). Rupa Health. https://www.rupahealth.com/biomarkers/testosterone

U.S. Food and Drug Administration. (2013). CLIA-Clinical Laboratory Improvement Amendments. CLIA-Clinical Laboratory Improvement Amendments.

Visser, T. J. (1996). Pathways of thyroid hormone metabolism. Acta Medica Austriaca, 23(1-2), 10–16. https://europepmc.org/article/med/8767510

Weinberg, J. (2022, March 31). How to tell if you have an estrogen imbalance. Www.rupahealth.com. https://www.rupahealth.com/post/a-functional-medicine-approach-to-estrogen-imbalance

Yoshimura, H. (2023, October 26). Diving into DHEA: The Overlooked Hormone and Its Impact on Women's Vitality. Rupa Health. https://www.rupahealth.com/post/diving-into-dhea-the-overlooked-hormone-and-its-impact-on-womens-vitality

Zima, T. (2017). Accreditation of Medical Laboratories – System, Process, Benefits for Labs. Journal of Medical Biochemistry, 36(3), 231–237. https://doi.org/10.1515/jomb-2017-0025

Subscribe to the Magazine for free to keep reading!
Subscribe for free to keep reading, If you are already subscribed, enter your email address to log back in.
Thanks for subscribing!
Oops! Something went wrong while submitting the form.
Are you a healthcare practitioner?
Thanks for subscribing!
Oops! Something went wrong while submitting the form.
See All Magazine Articles
Trusted Source
Rupa Health
Medical Education Platform
Visit Source
American Cancer Society
Foundation for Cancer Research
Visit Source
National Library of Medicine
Government Authority
Visit Source
Journal of The American College of Radiology
Peer Reviewed Journal
Visit Source
National Cancer Institute
Government Authority
Visit Source
World Health Organization (WHO)
Government Authority
Visit Source
The Journal of Pediatrics
Peer Reviewed Journal
Visit Source
CDC
Government Authority
Visit Source
Office of Dietary Supplements
Government Authority
Visit Source
National Heart Lung and Blood Institute
Government Authority
Visit Source
National Institutes of Health
Government Authority
Visit Source
Clinical Infectious Diseases
Peer Reviewed Journal
Visit Source
Brain
Peer Reviewed Journal
Visit Source
The Journal of Rheumatology
Peer Reviewed Journal
Visit Source
Journal of the National Cancer Institute (JNCI)
Peer Reviewed Journal
Visit Source
Journal of Cardiovascular Magnetic Resonance
Peer Reviewed Journal
Visit Source
Hepatology
Peer Reviewed Journal
Visit Source
The American Journal of Clinical Nutrition
Peer Reviewed Journal
Visit Source
The Journal of Bone and Joint Surgery
Peer Reviewed Journal
Visit Source
Kidney International
Peer Reviewed Journal
Visit Source
The Journal of Allergy and Clinical Immunology
Peer Reviewed Journal
Visit Source
Annals of Surgery
Peer Reviewed Journal
Visit Source
The Journal of Neurology, Neurosurgery & Psychiatry
Peer Reviewed Journal
Visit Source
Chest
Peer Reviewed Journal
Visit Source
Blood
Peer Reviewed Journal
Visit Source
Gastroenterology
Peer Reviewed Journal
Visit Source
The American Journal of Respiratory and Critical Care Medicine
Peer Reviewed Journal
Visit Source
The American Journal of Psychiatry
Peer Reviewed Journal
Visit Source
Diabetes Care
Peer Reviewed Journal
Visit Source
The Journal of the American College of Cardiology (JACC)
Peer Reviewed Journal
Visit Source
The Journal of Clinical Oncology (JCO)
Peer Reviewed Journal
Visit Source
Journal of Clinical Investigation (JCI)
Peer Reviewed Journal
Visit Source
Circulation
Peer Reviewed Journal
Visit Source
JAMA Internal Medicine
Peer Reviewed Journal
Visit Source
PLOS Medicine
Peer Reviewed Journal
Visit Source
Annals of Internal Medicine
Peer Reviewed Journal
Visit Source
Nature Medicine
Peer Reviewed Journal
Visit Source
The BMJ (British Medical Journal)
Peer Reviewed Journal
Visit Source
The Lancet
Peer Reviewed Journal
Visit Source
Journal of the American Medical Association (JAMA)
Peer Reviewed Journal
Visit Source
Pubmed
Comprehensive biomedical database
Visit Source
Harvard
Educational/Medical Institution
Visit Source
Cleveland Clinic
Educational/Medical Institution
Visit Source
Mayo Clinic
Educational/Medical Institution
Visit Source
The New England Journal of Medicine (NEJM)
Peer Reviewed Journal
Visit Source
Johns Hopkins
Educational/Medical Institution
Visit Source