A Root Cause Medicine Approach
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November 2, 2021

Constant Burping Is A Sign Of This Harmful Bacterial Overgrowth

Medically Reviewed by
Updated On
September 17, 2024

Small intestinal bacterial overgrowth (SIBO) is a debilitating condition that affects millions of people worldwide.

SIBO is commonly overlooked in the allopathic medical world but can affect up to 80% of patients with IBS.

Over time SIBO can lead to chronic inflammation & immune conditions and could be putting you at risk for other ailments, including poor absorption of food and nutrients.

A functional medicine approach to SIBO focusing on addressing the root cause of the issue, rather than treating the symptons.

What Causes SIBO

In order to maintain healthy gut bacteria, you must have proper stomach acid and normal bowel motility. Anything that affects these two components of digestion can allow harmful bacteria to overgrow.

Most gut bacteria live in the large intestine, the end of your digestive tract. But, in the case of SIBO, there is an overgrowth of bacteria in the small intestine

Gut bacteria are vital to our health, but they cause problems if they aren’t where they are supposed to be. Unlike your large intestine, your small intestine normally has relatively few bacteria due to the rapid flow of contents and the presence of bile. But if the small intestine’s function has slowed, it causes an ideal breeding ground for the overgrowth of bacteria.

The image illustrates the human digestive system, focusing on the small intestine with a magnified view of bacteria, highlighting an overgrowth.

Common Causes of SIBO

  • Low stomach acid
  • Acid reducing Medications (PPIs, Tums, Pepcid, Prilosec, immunosuppressants)
  • Gastroparesis
  • Celiac Disease
  • Chronic Constipation
  • Slow digestion/motility
  • Surgery (scar tissue: C section, endometriosis, hysterectomy, tummy tuck)
  • Hypothyroid (low thyroid hormone)
  • Stress (high cortisol)
  • A diet high in sugar, processed carbs, and alcohol
  • Infection (h. Pylori, e. Coli, klebsiella)
  • Food poisoning (most likely with IBS-D/SIBO-D)
  • Structural (ileocecal valve disorder, bariatric)

SIBO Signs and Symptoms

The two most common symptoms I see overlooked for SIBO are constant burping and bloating, which can worsen after meals and at the end of the day. Many people think these are common indigestion symptoms, but to an integrative gut health practitioner, this usually suggests issues with stomach acid production and possible overgrowth of bacteria in the small intestine.

When stomach acid is low and motility in the small intestine is slow, it provides the perfect breeding ground for bacteria to thrive. Gas is produced as a by-product of fermentation, which leads to chronic burping and bloating.

  • Constant Burping
  • Bloating worse at the end of the day
  • Patient feels better on Low FODMAP diet
  • Patients’ symptoms get better after antibiotic treatment
  • Feel worse after taking probiotics
  • An uncomfortable feeling of fullness or gas immediately after eating
  • Loose stools

Complications of SIBO

Small intestinal bacterial overgrowth (SIBO) can cause systemic problems, including:

  • Poor absorption of fats, carbohydrates, and proteins: Your small intestine is responsible for helping break down foods, and the overgrowth of bacteria can hinder this process, causing malabsorption, loose stools, gas, and bloat.
  • Vitamin deficiency: You need a healthy small intestine lining to absorb nutrients.
  • Weakened bones (osteoporosis): Over time nutrient depletion, including calcium depletion, can lead to bone diseases, such as osteoporosis.
  • Kidney stones: Poor calcium absorption can eventually result in kidney stones.

Functional Medicine Testing for SIBO

A SIBO breath test is the most common test for diagnosing SIBO. This is a non-invasive at-home test that evaluates bacterial overgrowth of the small intestine.

Patients begin by breathing into a tube after fasting overnight to get a base read. They then drink a specialized mixture to see if the bacteria in the small intestine releases hydrogen, methane, or a combo of both. After drinking, patients are asked to do a breath sample over a 3-hour time frame at 20 minutes, 40 minutes, 60 minutes, 90 minutes, 120 minutes, 150 minutes, and 180 minutes.

SIBO Test Results

Your patient will be positive for SIBO if the breath test shows one of the following:

  • Their hydrogen levels increase 20ppm during the 3 hours from the original starting point.
  • Their Methane levels increase 12 ppm during the 3 hours from the original starting point.
  • Combined (hydrogen + methane) increase 15 ppm during the 3 hours from the original starting point

Sample Report of Positive Hydrogen Dominant SIBO Report

The image shows a graph titled “Hydrogen (H2) and Methane (CH4) Breath Gases,” plotting the concentration of these gases in parts per million (ppm) across eight samples (S1 to S8). The blue line represents Hydrogen (H2) and the orange line represents Methane (CH4).

As you can see patient went from baseline of approximately 10 ppm to 60 ppm at the 90 min sample and continued to increase. This is over the increase of 20 ppm during the 3 hour test. Patient is therefore hydrogen dominant SIBO.

Functional Medicine Treatment of SIBO

Clinical management of SIBO involves nutritional therapy, antimicrobial therapy, motility supplements, and preventative measures to prevent reoccurrence.

For nutritional therapy, most practitioners will recommend a Low FODMAP or Elemental Diet to decrease the overgrowth of bacteria.

Low FODMAP Diet

The low FODMAP diet is a very restrictive temporary eating plan. FODMAP stands for Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols, which are short-chain carbohydrates that ferment in the small intestine and can feed the overgrown bacteria. Following a low FODMAP diet has been shown to decrease abnormally high levels of intestinal bacteria.

Low FODMAP is a three-step elimination diet:

  • First, eliminate high FODMAP foods.
  • Slowly reintroduce FODMAPs after 4 to 6 weeks to see which foods cause pain, gas, or bloat.
  • Once you identify the foods that cause symptoms, you can avoid or limit them while going back to enjoying the others.

Elemental Diet

Another option functional medicine practitioners like to use to kill off overgrown bacteria quickly is the elemental diet. The elemental diet has a very high success rate and only takes two weeks.

The elemental diet is much stricter than low fodmap and requires patients to drink the elemental nutrient drink in place of all meals for 2-3 weeks. This diet works by starving bacteria. Herbal antimicrobial treatment is not needed if patients are prescribed the elemental diet.

Herbal Antimicrobials

Functional Medicine Practitioners will commonly use herbal antimicrobials (antibiotics) alongside a low FODMAP diet for 4-6 weeks. Patients should be warned that they will have bacteria and possible candida die off (if present) and may feel worse before feeling better up to 3-4 weeks during treatment.

Treating SIBO with herbal antimicrobials depends on if the patient is Methane or Hydrogen dominant. The most common herbs used are allicin and berberine.

  • Methane Dominant SIBO: Allicin
  • Hydrogen Dominant SIBO: Berberine
  • Methane & Hydrogen Dominant SIBO: Allicin + Berberine

Prevention

It’s vital to assess what caused the SIBO in the first place to prevent future relapse.

Patients will need to be on a prokinetic (supplement to help motility) for at least 90 days after treatment. Remember, slow motility allows bacteria to stay in the small intestine for too long.

I also recommend prescribing digestive enzymes as well as testing for hypochloridria (low stomach acid). If patient has low stomach acid, increasing acid levels is essential.

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Summary

SIBO is commonly overlooked in the medical world but can affect up to 80% of patients with IBS. An easy at-home test can give your patients a definitive diagnosis, and the proper treatment protocols can provide your patients better overall health and outlook on life.

Small intestinal bacterial overgrowth (SIBO) is a condition that affects many people worldwide.

SIBO is commonly overlooked in the allopathic medical world but may affect a significant number of patients with IBS.

Over time, SIBO can contribute to chronic inflammation and may be associated with other health concerns, including challenges with absorbing food and nutrients.

A functional medicine approach to SIBO focuses on addressing the underlying factors that may contribute to the condition, rather than solely focusing on symptoms.

What Causes SIBO

To support healthy gut bacteria, it is important to have proper stomach acid levels and normal bowel motility. Factors that affect these components of digestion can allow bacteria to grow excessively.

Most gut bacteria live in the large intestine, the end of your digestive tract. But, in the case of SIBO, there is an overgrowth of bacteria in the small intestine.

Gut bacteria are vital to our health, but they can cause problems if they aren’t where they are supposed to be. Unlike your large intestine, your small intestine normally has relatively few bacteria due to the rapid flow of contents and the presence of bile. If the small intestine’s function slows, it may create an environment conducive to bacterial overgrowth.

The image illustrates the human digestive system, focusing on the small intestine with a magnified view of bacteria, highlighting an overgrowth.

Common Factors Associated with SIBO

  • Low stomach acid
  • Acid reducing Medications (PPIs, Tums, Pepcid, Prilosec, immunosuppressants)
  • Gastroparesis
  • Celiac Disease
  • Chronic Constipation
  • Slow digestion/motility
  • Surgery (scar tissue: C section, endometriosis, hysterectomy, tummy tuck)
  • Hypothyroid (low thyroid hormone)
  • Stress (high cortisol)
  • A diet high in sugar, processed carbs, and alcohol
  • Infection (h. Pylori, e. Coli, klebsiella)
  • Food poisoning (most likely with IBS-D/SIBO-D)
  • Structural (ileocecal valve disorder, bariatric)

SIBO Signs and Symptoms

Two common symptoms that may be associated with SIBO are frequent burping and bloating, which can worsen after meals and at the end of the day. Many people think these are common indigestion symptoms, but to an integrative gut health practitioner, this may suggest issues with stomach acid production and possible bacterial overgrowth in the small intestine.

When stomach acid is low and motility in the small intestine is slow, it may create an environment where bacteria can thrive. Gas is produced as a by-product of fermentation, which can lead to frequent burping and bloating.

  • Frequent Burping
  • Bloating worse at the end of the day
  • Patient feels better on Low FODMAP diet
  • Patients’ symptoms may improve after certain treatments
  • Feel worse after taking probiotics
  • An uncomfortable feeling of fullness or gas immediately after eating
  • Loose stools

Potential Complications of SIBO

Small intestinal bacterial overgrowth (SIBO) may be associated with systemic issues, including:

  • Challenges with absorbing fats, carbohydrates, and proteins: Your small intestine helps break down foods, and bacterial overgrowth can interfere with this process, potentially leading to malabsorption, loose stools, gas, and bloat.
  • Vitamin deficiency: A healthy small intestine lining is important for nutrient absorption.
  • Weakened bones (osteoporosis): Over time, nutrient depletion, including calcium depletion, may contribute to bone health issues, such as osteoporosis.
  • Kidney stones: Poor calcium absorption may eventually be associated with kidney stones.

Functional Medicine Testing for SIBO

A SIBO breath test is a common method for evaluating SIBO. This is a non-invasive at-home test that assesses bacterial overgrowth in the small intestine.

Patients begin by breathing into a tube after fasting overnight to get a base read. They then drink a specialized mixture to see if the bacteria in the small intestine releases hydrogen, methane, or a combo of both. After drinking, patients are asked to do a breath sample over a 3-hour time frame at 20 minutes, 40 minutes, 60 minutes, 90 minutes, 120 minutes, 150 minutes, and 180 minutes.

SIBO Test Results

A positive result for SIBO may be indicated if the breath test shows one of the following:

  • Their hydrogen levels increase 20ppm during the 3 hours from the original starting point.
  • Their Methane levels increase 12 ppm during the 3 hours from the original starting point.
  • Combined (hydrogen + methane) increase 15 ppm during the 3 hours from the original starting point

Sample Report of Positive Hydrogen Dominant SIBO Report

The image shows a graph titled “Hydrogen (H2) and Methane (CH4) Breath Gases,” plotting the concentration of these gases in parts per million (ppm) across eight samples (S1 to S8). The blue line represents Hydrogen (H2) and the orange line represents Methane (CH4).

As you can see, the patient went from a baseline of approximately 10 ppm to 60 ppm at the 90 min sample and continued to increase. This is over the increase of 20 ppm during the 3-hour test. The patient is therefore hydrogen dominant SIBO.

Functional Medicine Approaches to SIBO

Clinical management of SIBO may involve nutritional strategies, supportive therapies, and measures to help maintain gut health.

For nutritional strategies, some practitioners may suggest a Low FODMAP or Elemental Diet to help manage bacterial levels.

Low FODMAP Diet

The low FODMAP diet is a temporary eating plan. FODMAP stands for Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols, which are short-chain carbohydrates that ferment in the small intestine and may contribute to bacterial growth. Following a low FODMAP diet has been shown to help manage intestinal bacteria levels.

Low FODMAP is a three-step elimination diet:

  • First, eliminate high FODMAP foods.
  • Slowly reintroduce FODMAPs after 4 to 6 weeks to see which foods may cause discomfort.
  • Once you identify the foods that cause symptoms, you can avoid or limit them while going back to enjoying the others.

Elemental Diet

Another option some practitioners may consider is the elemental diet. The elemental diet is a more restrictive approach and involves consuming a nutrient drink in place of meals for a short period. This diet aims to manage bacterial levels by limiting their food sources.

Herbal Support

Some practitioners may use herbal supplements alongside dietary changes. Patients should be aware that they may experience changes in symptoms during this time.

Approaches to managing SIBO with herbal support may depend on whether the patient is Methane or Hydrogen dominant. Common herbs used include allicin and berberine.

  • Methane Dominant SIBO: Allicin
  • Hydrogen Dominant SIBO: Berberine
  • Methane & Hydrogen Dominant SIBO: Allicin + Berberine

Prevention

It’s important to consider factors that may have contributed to SIBO to help prevent future occurrences.

Some patients may benefit from using supplements that support motility for a period after treatment. Supporting normal motility can help maintain gut health.

Consulting with a healthcare provider about digestive enzymes and stomach acid levels may also be beneficial.

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Summary

SIBO is commonly overlooked in the medical world but may affect a significant number of patients with IBS. An at-home test can help provide insights, and appropriate management strategies may support better overall health and well-being.

The information provided is not intended to be a substitute for professional medical advice. Always consult with your doctor or other qualified healthcare provider before taking any dietary supplement or making any changes to your diet or exercise routine.

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