Endocrinology
|
June 28, 2024

The Link Between Testosterone and Blood Pressure

Medically Reviewed by
Updated On
September 17, 2024

Believe it or not, testosterone levels can affect blood pressure; this phenomenon is highly relevant for men over age 45 due to natural declines in testosterone that typically occur with aging. Furthermore, about half of the adults in the United States have high blood pressure, many of whom don't know they have it.

This article discusses the impact, potential treatments, and lifestyle considerations regarding the link between testosterone and blood pressure.

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What Is Testosterone?

Testosterone is a chemical messenger critical to male and female body functions. Testosterone impacts mental, sexual, and physical health. Testosterone contributes to:

  • Sense of well-being
  • Red blood cell formation
  • Muscle mass
  • Bone health
  • Sex organ functioning
  • Reproduction
  • Sex drive

Maintaining testosterone balance lessens the risk of bothersome symptoms and complications, including high blood pressure.

What Is Low Testosterone (Low T)?

Low testosterone, also referred to as low T or male hypogonadism, is a condition in which the body doesn't produce enough testosterone. The clinical threshold for having low testosterone is less than 300 ng/dL.

What Are The Causes of Low Testosterone?

Causes of male hypogonadism may be primary or secondary.

Primary Causes 

  • Undescended testicles or absence of testicles
  • Genetic/inherited conditions
  • Testicular injuries or inflammation
  • Chemotherapy and radiation therapy 
  • Tumors
  • Anabolic steroid use

Secondary Hypogonadism

What Are The Symptoms of Low Testosterone?

The symptoms of low testosterone include:

Low testosterone in boys can negatively affect their growth, development, and strength.

What Is Blood Pressure?

Blood pressure measures the pressure blood exerts inside blood vessel walls. 

  • Systolic blood pressure: The first (top) number measures the pressure blood exerts against artery walls when the heart contracts.
  • Diastolic blood pressure: The second (bottom) number measures the pressure blood exerts against blood vessel walls as the heart muscle rests between contractions. 

A healthy blood pressure reading is less than 120/80 mm Hg. About 70% of Americans have high blood pressure at some point in their lifetime.

High blood pressure is a risk factor for heart disease, heart attack, heart failure, and stroke

The Link Between Testosterone and Blood Pressure

Low testosterone can lead to conditions that indirectly increase blood pressure, such as higher body fat and insulin resistance

Studies show that lower total testosterone is a risk factor for high blood pressure, and both low and high testosterone levels are linked to a higher risk of heart problems.

Therefore, it is essential to maintain total testosterone levels that are within acceptable ranges, which are:

  • Males: 240-950 ng/dL
  • Females: 8-60 ng/dL

Research has shown that hypogonadal men who underwent testosterone therapy experienced reductions in blood pressure, with the most significant improvements occurring in men with higher baseline hypertension.  

Impact of Low T on Cardiovascular Health

Testosterone influences cardiovascular function and blood vessel health, as heart muscle cells and blood vessels have receptors that latch to testosterone.

Studies have found that low T concentrations are linked to premature coronary artery disease (CAD) and unfavorable effects on heart disease risk factors. Additional research has found that testosterone replacement therapy (TRT) protects against heart issues and mortality in men with testosterone deficiency

Testosterone also plays a critical role in healthy weight management and metabolism, impacting blood pressure and the risk of heart problems linked to hypertension. 

Managing and Treating Low T

Managing and treating low T typically involves making healthy lifestyle changes, undergoing TRT, or both.

TRT

The different forms of TRT include:

  • Injections
  • Gels
  • Patches
  • Pellets
  • Creams
  • Pills
  • Buccal tablets

The benefits of TRT include normalized testosterone levels and a lower risk of hypertension, heart disease, and bothersome symptoms like fatigue and muscle weakness. 

However, not everyone is a candidate for TRT. Individuals with the following health history may not be eligible to receive this therapy:

Furthermore, TRT may cause several side effects:

  • Oily skin, acne, or skin irritation
  • Fluid retention
  • Difficulty urinating
  • Worsening sleep apnea
  • Smaller testicles
  • Breast tenderness or changes

Patients should consult with a provider regarding side effects or medical concerns. 

Preventive Measures and Lifestyle Choices

There are several prevention measures and healthy lifestyle changes that can maximize heart health and testosterone production.

Testosterone-Boosting Foods

The following foods appear to support healthy testosterone levels:

  • Whole grains, such as whole-grain cereals, brown rice, oatmeal, quinoa
  • Protein, such as poultry, seafood, lean meats, fatty fish, eggs
  • Fruits and vegetables, including dark green vegetables, leafy greens, berries, and more
  • Legumes like chickpeas, navy beans, black beans,  lentils, kidney beans
  • Healthy fats, including olive oil, fish oil, nuts, seeds, avocados
  • Dietary supplements, such as ashwagandha, Asian red ginseng, fenugreek seed, Tribulus terrestris, Coleus forskohlii root, and DHEA

Patients should always check in with their doctor before taking dietary supplements

It is also helpful to limit or avoid:

  • Added sugars, desserts, and pastries
  • Refined carbohydrates (white bread, white rice)
  • Sugar-sweetened beverages
  • Trans fats, fried foods, highly processed foods, and fast foods
  • Alcohol

Other Lifestyle Changes

Lifestyle adjustments that support testosterone balance and minimize the risk of high blood pressure include:

When to See a Doctor

Symptoms of heart issues or low testosterone that require medical attention include:

  • Shortness of breath
  • Chest tightness or pain
  • Nosebleeds
  • Headaches
  • Extreme fatigue
  • Problems concentrating or mood changes
  • Erectile dysfunction (ED) or infertility
  • Coldness, numbness, color changes, cramping, or weakness in the lower limbs
  • Other new, unusual, or alarming symptoms

Patients with risk factors should undergo routine screenings for low testosterone and high blood pressure to detect potential problems early, reducing the risk of complications. 

[signup]

Key Takeaways

  • Clinical research suggests a link between testosterone and blood pressure.
  • Too little or too much testosterone increases the risk of elevated blood pressure, heart disease, heart attacks, strokes, or other heart problems.
  • It is vital to check hormone levels routinely in patients with symptoms of low testosterone or its risk factors, including older age, obesity, and underlying medical conditions.
  • Healthy lifestyle changes and undergoing TRT as needed can enhance hormone health, improve blood pressure control, and minimize the risk of heart problems. 

Believe it or not, testosterone levels may influence blood pressure; this phenomenon is particularly relevant for men over age 45 due to natural declines in testosterone that typically occur with aging. Furthermore, about half of the adults in the United States have high blood pressure, many of whom don't know they have it.

This article discusses the potential impact, considerations, and lifestyle factors regarding the link between testosterone and blood pressure.

[signup]

What Is Testosterone?

Testosterone is a chemical messenger important for various body functions in both males and females. Testosterone contributes to:

  • Sense of well-being
  • Red blood cell formation
  • Muscle mass
  • Bone health
  • Sex organ functioning
  • Reproduction
  • Sex drive

Maintaining testosterone balance may help reduce the risk of bothersome symptoms and complications, including high blood pressure.

What Is Low Testosterone (Low T)?

Low testosterone, also referred to as low T or male hypogonadism, is a condition in which the body doesn't produce enough testosterone. The clinical threshold for having low testosterone is less than 300 ng/dL.

What Are The Causes of Low Testosterone?

Causes of male hypogonadism may be primary or secondary.

Primary Causes 

  • Undescended testicles or absence of testicles
  • Genetic/inherited conditions
  • Testicular injuries or inflammation
  • Chemotherapy and radiation therapy 
  • Tumors
  • Anabolic steroid use

Secondary Hypogonadism

What Are The Symptoms of Low Testosterone?

The symptoms of low testosterone include:

Low testosterone in boys can affect their growth, development, and strength.

What Is Blood Pressure?

Blood pressure measures the pressure blood exerts inside blood vessel walls. 

  • Systolic blood pressure: The first (top) number measures the pressure blood exerts against artery walls when the heart contracts.
  • Diastolic blood pressure: The second (bottom) number measures the pressure blood exerts against blood vessel walls as the heart muscle rests between contractions. 

A healthy blood pressure reading is less than 120/80 mm Hg. About 70% of Americans have high blood pressure at some point in their lifetime.

High blood pressure is a risk factor for heart disease, heart attack, heart failure, and stroke

The Link Between Testosterone and Blood Pressure

Low testosterone may contribute to conditions that can indirectly increase blood pressure, such as higher body fat and insulin resistance

Studies show that lower total testosterone is associated with a risk of high blood pressure, and both low and high testosterone levels are linked to a higher risk of heart problems.

Therefore, it is important to maintain total testosterone levels that are within acceptable ranges, which are:

  • Males: 240-950 ng/dL
  • Females: 8-60 ng/dL

Research has shown that hypogonadal men who underwent testosterone therapy experienced reductions in blood pressure, with the most significant improvements occurring in men with higher baseline hypertension.  

Impact of Low T on Cardiovascular Health

Testosterone may influence cardiovascular function and blood vessel health, as heart muscle cells and blood vessels have receptors that interact with testosterone.

Studies have found that low T concentrations are linked to premature coronary artery disease (CAD) and unfavorable effects on heart disease risk factors. Additional research has found that testosterone replacement therapy (TRT) may support heart health and reduce mortality in men with testosterone deficiency

Testosterone also plays a role in healthy weight management and metabolism, which can impact blood pressure and the risk of heart problems linked to hypertension. 

Managing and Treating Low T

Managing and treating low T typically involves making healthy lifestyle changes, undergoing TRT, or both.

TRT

The different forms of TRT include:

  • Injections
  • Gels
  • Patches
  • Pellets
  • Creams
  • Pills
  • Buccal tablets

The benefits of TRT may include normalized testosterone levels and a potential reduction in the risk of hypertension, heart disease, and bothersome symptoms like fatigue and muscle weakness. 

However, not everyone is a candidate for TRT. Individuals with the following health history may not be eligible to receive this therapy:

Furthermore, TRT may cause several side effects:

  • Oily skin, acne, or skin irritation
  • Fluid retention
  • Difficulty urinating
  • Worsening sleep apnea
  • Smaller testicles
  • Breast tenderness or changes

Patients should consult with a provider regarding side effects or medical concerns. 

Preventive Measures and Lifestyle Choices

There are several prevention measures and healthy lifestyle changes that can support heart health and testosterone production.

Testosterone-Boosting Foods

The following foods may support healthy testosterone levels:

  • Whole grains, such as whole-grain cereals, brown rice, oatmeal, quinoa
  • Protein, such as poultry, seafood, lean meats, fatty fish, eggs
  • Fruits and vegetables, including dark green vegetables, leafy greens, berries, and more
  • Legumes like chickpeas, navy beans, black beans,  lentils, kidney beans
  • Healthy fats, including olive oil, fish oil, nuts, seeds, avocados
  • Dietary supplements, such as ashwagandha, Asian red ginseng, fenugreek seed, Tribulus terrestris, Coleus forskohlii root, and DHEA

Patients should always check in with their doctor before taking dietary supplements

It is also helpful to limit or avoid:

  • Added sugars, desserts, and pastries
  • Refined carbohydrates (white bread, white rice)
  • Sugar-sweetened beverages
  • Trans fats, fried foods, highly processed foods, and fast foods
  • Alcohol

Other Lifestyle Changes

Lifestyle adjustments that may support testosterone balance and help manage the risk of high blood pressure include:

When to See a Doctor

Symptoms of heart issues or low testosterone that may require medical attention include:

  • Shortness of breath
  • Chest tightness or pain
  • Nosebleeds
  • Headaches
  • Extreme fatigue
  • Problems concentrating or mood changes
  • Erectile dysfunction (ED) or infertility
  • Coldness, numbness, color changes, cramping, or weakness in the lower limbs
  • Other new, unusual, or alarming symptoms

Patients with risk factors should consider routine screenings for low testosterone and high blood pressure to detect potential problems early, which may help reduce the risk of complications. 

[signup]

Key Takeaways

  • Clinical research suggests a link between testosterone and blood pressure.
  • Too little or too much testosterone may increase the risk of elevated blood pressure, heart disease, heart attacks, strokes, or other heart problems.
  • It is important to check hormone levels routinely in patients with symptoms of low testosterone or its risk factors, including older age, obesity, and underlying medical conditions.
  • Healthy lifestyle changes and undergoing TRT as needed can support hormone health, help manage blood pressure, and potentially reduce the risk of heart problems. 
The information provided is not intended to be a substitute for professional medical advice. Always consult with your doctor or other qualified healthcare provider before taking any dietary supplement or making any changes to your diet or exercise routine.

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Journal of The American College of Radiology
Peer Reviewed Journal
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National Cancer Institute
Government Authority
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World Health Organization (WHO)
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The Journal of Pediatrics
Peer Reviewed Journal
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CDC
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Office of Dietary Supplements
Government Authority
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National Heart Lung and Blood Institute
Government Authority
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National Institutes of Health
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Clinical Infectious Diseases
Peer Reviewed Journal
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Brain
Peer Reviewed Journal
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The Journal of Rheumatology
Peer Reviewed Journal
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Journal of the National Cancer Institute (JNCI)
Peer Reviewed Journal
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Journal of Cardiovascular Magnetic Resonance
Peer Reviewed Journal
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Hepatology
Peer Reviewed Journal
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The American Journal of Clinical Nutrition
Peer Reviewed Journal
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The Journal of Bone and Joint Surgery
Peer Reviewed Journal
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Kidney International
Peer Reviewed Journal
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The Journal of Allergy and Clinical Immunology
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Annals of Surgery
Peer Reviewed Journal
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Chest
Peer Reviewed Journal
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The Journal of Neurology, Neurosurgery & Psychiatry
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Blood
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Gastroenterology
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The American Journal of Respiratory and Critical Care Medicine
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The American Journal of Psychiatry
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Diabetes Care
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The Journal of the American College of Cardiology (JACC)
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The Journal of Clinical Oncology (JCO)
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Journal of Clinical Investigation (JCI)
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Circulation
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JAMA Internal Medicine
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PLOS Medicine
Peer Reviewed Journal
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Annals of Internal Medicine
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Nature Medicine
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The BMJ (British Medical Journal)
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The Lancet
Peer Reviewed Journal
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Journal of the American Medical Association (JAMA)
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Pubmed
Comprehensive biomedical database
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Harvard
Educational/Medical Institution
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Cleveland Clinic
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Mayo Clinic
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The New England Journal of Medicine (NEJM)
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Johns Hopkins
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