Nutrition
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February 6, 2024

Magnesium for Joint Pain: How a Simple Mineral Can Give You Your Life Back

Written By
Medically Reviewed by
Updated On
September 18, 2024

If you're experiencing joint pain, you understand all too well how it can stand in the way of enjoying life to its fullest. It can limit your movements, bring down your spirits, and reduce the pleasure you get from daily activities.Β 

As the world increasingly turns towards natural healing methods, the search for non-pharmaceutical remedies to ease joint pain is becoming more popular. This is where magnesium steps in, not as a mere supplement but as a potential beacon of relief for joint pain. As we discuss the science behind magnesium's benefits and look at practical ways to incorporate it into daily routines, it is easy to see the life-changing potential in the natural management of joint pain.Β 

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What is Magnesium?

Magnesium is a mineral that is essential for numerous bodily functions. It is a key player in over 300 enzymatic reactions, impacting everything from energy production to DNA synthesis. One of magnesium's primary functions in the body is acting as a cofactor in enzymatic reactions. A "cofactor" can be likened to a helper molecule that is essential for these reactions to occur successfully. Reactions that require magnesium include processes that are vital for life, such as nerve and muscle function, protein synthesis, maintaining proper blood glucose levels, and blood pressure regulation.

Magnesium's role is particularly prominent in muscle and nerve function. It helps regulate neuromuscular signals and muscle contractions. Muscle cramps often indicate magnesium deficiency, as this mineral helps muscles relax after contraction. While this relaxation is crucial for musculoskeletal function during physical activities, the heart muscle has its own significant relationship with magnesium.Β 

Magnesium plays a critical role in cardiovascular health, as it helps to maintain a healthy heartbeat and proper function of the blood vessels. Magnesium aids in controlling blood pressure and supports the proper transport of other minerals, like potassium and calcium, which are crucial for healthy heart function. In some cases, it can be used to prevent and manage conditions such as hypertension and heart disease.

Additionally, magnesium is fundamental to bone health. It functions with calcium and vitamin D to maintain strong bones and teeth. While calcium is often highlighted as the main mineral for bone health, magnesium is equally important. It helps to activate vitamin D, which in turn aids calcium absorption in the bones.Β 

It is also important to note that magnesium has significant implications for mental health: it aids in regulating neurotransmitters, which send messages throughout the brain and nervous system. Adequate levels of magnesium have been associated with a lower risk of conditions like depression and anxiety. It helps maintain brain function and mood regulation, making it a key element in mental well-being.

What Does Magnesium Do For Muscles and Joints?

Magnesium plays an essential role in the health and functioning of muscles and joints. Firstly, magnesium acts as a natural calcium antagonist in the realm of muscle function. Calcium ions flood into the muscle cells when muscles contract, triggering contraction. Magnesium counters this action by helping to push calcium out of the cells, which leads to muscle relaxation. This balance between calcium and magnesium is essential for proper muscle function. Magnesium also plays a role in energy production within muscle cells. It is vital for creating adenosine triphosphate (ATP), the primary energy molecule in the body.Β 

Magnesium's benefits are more indirect but equally significant in the context of joint health. As we saw, it contributes to bone health, which is essential for joint function. Magnesium helps regulate calcium transport, a crucial factor in maintaining bone density and preventing conditions like osteoporosis, which can indirectly affect joint health.Β 

Inflammation is another common driver of joint pain and can contribute to arthritis. By reducing inflammation, magnesium can help alleviate joint pain and improve joint mobility. This anti-inflammatory effect benefits the joints directly and helps reduce muscle stiffness and soreness, contributing to overall musculoskeletal health.

What Type of Magnesium is Best for Joint Pain?

Magnesium glycinate and magnesium malate are two particularly effective forms when choosing the best type of magnesium for joint pain.

Magnesium Glycinate, a combination of magnesium and glycine, is a particularly effective supplement for managing joint pain. Magnesium glycinate is a pairing of magnesium and glycine that offers notable bioavailability. This means your body can absorb and use it more effectively than other magnesium forms. Because magnesium helps keep muscles more relaxed, this can ease the tension exerted upon joints, explicitly addressing the pain response.Β 

An additional advantage of magnesium glycinate is its relatively gentle effect on the digestive system. Compared to other magnesium supplements, the glycinate form increases plasma levels of magnesium without causing gastrointestinal side effects like diarrhea.Β 

Magnesium Malate, a combination of magnesium and malic acid, also offers unique benefits due to its components and synergistic effects on the body. Malic acid is involved in the Krebs cycle, a crucial part of cellular energy production. This can be particularly beneficial for individuals with joint pain, as improved energy production at the cellular level can enhance muscle function and reduce muscle fatigueβ€”symptoms often associated with joint discomfort.

Research also suggests magnesium malate may be especially beneficial for conditions like fibromyalgia and chronic fatigue syndrome.

Does a Lack of Magnesium Cause Joint Pain?

While a direct cause-and-effect link is complex and influenced by various factors, evidence suggests that a lack of magnesium in the body can exacerbate or even potentially contribute to the development of joint pain. Magnesium plays a critical role in preserving healthy bone structure and function. It is essential for the absorption and metabolism of calcium, which is crucial for bone health. When magnesium levels are low, calcium may not be efficiently absorbed, leading to weaker bones and an increased risk of joint-related problems.Β 

Magnesium also affects the health of cartilage in the joints; inadequate magnesium can lead to the deterioration of cartilage, exacerbating conditions like osteoarthritis.

Magnesium has natural anti-inflammatory properties, and inflammation is a significant factor in many joint pain conditions, including arthritis and rheumatism. Because magnesium has natural anti-inflammatory properties, a magnesium deficiency can result in heightened inflammatory responses, thereby contributing to increased joint pain and stiffness.Β 

How to Test Magnesium Levels

To assess magnesium levels in the body, several testing methods are available, each with its own advantages and considerations:

Serum Magnesium is the most common test and involves a basic blood draw. However, it primarily measures the magnesium in your blood, not within your cells, where most of the body's magnesium is stored. While a low serum magnesium level likely indicates a deficiency, normal results can be misleading, as they don't always reflect cellular magnesium levels​

RBC Magnesium: This test measures magnesium in red blood cells and is considered more accurate than serum testing for assessing magnesium levels. It's a better indicator of the body's magnesium status because, in the case of deficiency, the body may pull magnesium from the red blood cells to replenish serum levels. A RBC test that shows magnesium deficient red blood cells indicates the body has inadequate magnesium to put into storage and circulate in the serum. It is pulling on storage to meet the body’s needs.Β 

Micronutrient Testing: The Micronutrient Test by SpectraCell Laboratories offers a comprehensive assessment of essential vitamins, minerals, antioxidants, fatty acids, and amino acids, including magnesium. This test provides a detailed evaluation of both extracellular (outside cells) and intracellular (inside cells) micronutrient levels.

Can Adequate Magnesium Come From the Diet?

Adequate magnesium levels can generally be achieved through a well-balanced, well-considered diet. The Recommended Dietary Allowance (RDA) for magnesium varies and may not be sufficient for many people's needs: adult men are said to minimally require about 400-420 mg per day, while adult women are said to require approximately 310-320 mg. Foods rich in magnesium include leafy green vegetables like spinach, nuts and seeds such as pumpkin seeds and almonds, along with whole grains and legumes such as beans and lentils, and certain fish, including salmon. Including a variety of these foods in your daily diet can help you meet your magnesium needs.

How Much Magnesium to Take

Magnesium supplementation is often necessary when dietary intake is insufficient or in certain health conditions. The recommended dose can vary significantly depending on individual factors such as age, gender, and specific health needs. The recommended supplement dose varies based on age, gender, and individual health needs. The accepted dosages for magnesium supplementation are 65 mg/day for children ages 1-3, 110 mg/day for children ages 4-8, and 350 mg/day for adults and children ages nine and up.

[signup]

Magnesium for Joint Pain: Key Takeaways

Magnesium deficiency can contribute to joint pain due to its key role in muscle function, bone health, nerve regulation, and anti-inflammatory properties. Ensuring adequate magnesium intake is crucial for muscle contraction and relaxation, energy production in muscle cells, and reducing inflammation, all of which can help alleviate joint pain. By supporting bone health and the synthesis of essential structural proteins, magnesium also enhances joints' overall integrity and function. Therefore, Adequate magnesium levels are vital for healthy muscles and joints, significantly reducing musculoskeletal discomfort and improving mobility.

If you're experiencing joint pain, you understand all too well how it can stand in the way of enjoying life to its fullest. It can limit your movements, bring down your spirits, and reduce the pleasure you get from daily activities.Β 

As the world increasingly turns towards natural methods to support health, the search for non-pharmaceutical options to ease joint discomfort is becoming more popular. This is where magnesium steps in, not as a mere supplement but as a potential aid for joint health. As we discuss the science behind magnesium's benefits and look at practical ways to incorporate it into daily routines, it is easy to see the potential in the natural management of joint discomfort.Β 

[signup]

What is Magnesium?

Magnesium is a mineral that is essential for numerous bodily functions. It is a key player in over 300 enzymatic reactions, impacting everything from energy production to DNA synthesis. One of magnesium's primary functions in the body is acting as a cofactor in enzymatic reactions. A "cofactor" can be likened to a helper molecule that is essential for these reactions to occur successfully. Reactions that require magnesium include processes that are vital for life, such as nerve and muscle function, protein synthesis, maintaining proper blood glucose levels, and blood pressure regulation.

Magnesium's role is particularly prominent in muscle and nerve function. It helps regulate neuromuscular signals and muscle contractions. Muscle cramps often indicate magnesium deficiency, as this mineral helps muscles relax after contraction. While this relaxation is crucial for musculoskeletal function during physical activities, the heart muscle has its own significant relationship with magnesium.Β 

Magnesium plays a critical role in cardiovascular health, as it helps to maintain a healthy heartbeat and proper function of the blood vessels. Magnesium aids in controlling blood pressure and supports the proper transport of other minerals, like potassium and calcium, which are crucial for healthy heart function. In some cases, it can be used to support the management of conditions such as hypertension and heart health.

Additionally, magnesium is fundamental to bone health. It functions with calcium and vitamin D to maintain strong bones and teeth. While calcium is often highlighted as the main mineral for bone health, magnesium is equally important. It helps to activate vitamin D, which in turn aids calcium absorption in the bones.Β 

It is also important to note that magnesium has significant implications for mental health: it aids in regulating neurotransmitters, which send messages throughout the brain and nervous system. Adequate levels of magnesium have been associated with a lower risk of conditions like depression and anxiety. It helps maintain brain function and mood regulation, making it a key element in mental well-being.

What Does Magnesium Do For Muscles and Joints?

Magnesium plays an essential role in the health and functioning of muscles and joints. Firstly, magnesium acts as a natural calcium antagonist in the realm of muscle function. Calcium ions flood into the muscle cells when muscles contract, triggering contraction. Magnesium counters this action by helping to push calcium out of the cells, which leads to muscle relaxation. This balance between calcium and magnesium is essential for proper muscle function. Magnesium also plays a role in energy production within muscle cells. It is vital for creating adenosine triphosphate (ATP), the primary energy molecule in the body.Β 

Magnesium's benefits are more indirect but equally significant in the context of joint health. As we saw, it contributes to bone health, which is essential for joint function. Magnesium helps regulate calcium transport, a crucial factor in maintaining bone density and supporting joint health.Β 

Inflammation is another common driver of joint discomfort and can contribute to arthritis. By supporting the reduction of inflammation, magnesium can help alleviate joint discomfort and improve joint mobility. This supportive effect benefits the joints directly and helps reduce muscle stiffness and soreness, contributing to overall musculoskeletal health.

What Type of Magnesium is Best for Joint Health?

Magnesium glycinate and magnesium malate are two particularly effective forms when choosing the best type of magnesium for joint health.

Magnesium Glycinate, a combination of magnesium and glycine, is a particularly effective supplement for supporting joint health. Magnesium glycinate is a pairing of magnesium and glycine that offers notable bioavailability. This means your body can absorb and use it more effectively than other magnesium forms. Because magnesium helps keep muscles more relaxed, this can ease the tension exerted upon joints, explicitly addressing the discomfort response.Β 

An additional advantage of magnesium glycinate is its relatively gentle effect on the digestive system. Compared to other magnesium supplements, the glycinate form increases plasma levels of magnesium without causing gastrointestinal side effects like diarrhea.Β 

Magnesium Malate, a combination of magnesium and malic acid, also offers unique benefits due to its components and synergistic effects on the body. Malic acid is involved in the Krebs cycle, a crucial part of cellular energy production. This can be particularly beneficial for individuals with joint discomfort, as improved energy production at the cellular level can enhance muscle function and reduce muscle fatigueβ€”symptoms often associated with joint discomfort.

Research also suggests magnesium malate may be especially beneficial for conditions like fibromyalgia and chronic fatigue syndrome.

Does a Lack of Magnesium Contribute to Joint Discomfort?

While a direct cause-and-effect link is complex and influenced by various factors, evidence suggests that a lack of magnesium in the body can exacerbate or even potentially contribute to the development of joint discomfort. Magnesium plays a critical role in preserving healthy bone structure and function. It is essential for the absorption and metabolism of calcium, which is crucial for bone health. When magnesium levels are low, calcium may not be efficiently absorbed, leading to weaker bones and an increased risk of joint-related problems.Β 

Magnesium also affects the health of cartilage in the joints; inadequate magnesium can lead to the deterioration of cartilage, exacerbating conditions like osteoarthritis.

Magnesium has natural anti-inflammatory properties, and inflammation is a significant factor in many joint discomfort conditions, including arthritis and rheumatism. Because magnesium has natural anti-inflammatory properties, a magnesium deficiency can result in heightened inflammatory responses, thereby contributing to increased joint discomfort and stiffness.Β 

How to Test Magnesium Levels

To assess magnesium levels in the body, several testing methods are available, each with its own advantages and considerations:

Serum Magnesium is the most common test and involves a basic blood draw. However, it primarily measures the magnesium in your blood, not within your cells, where most of the body's magnesium is stored. While a low serum magnesium level likely indicates a deficiency, normal results can be misleading, as they don't always reflect cellular magnesium levels​

RBC Magnesium: This test measures magnesium in red blood cells and is considered more accurate than serum testing for assessing magnesium levels. It's a better indicator of the body's magnesium status because, in the case of deficiency, the body may pull magnesium from the red blood cells to replenish serum levels. A RBC test that shows magnesium deficient red blood cells indicates the body has inadequate magnesium to put into storage and circulate in the serum. It is pulling on storage to meet the body’s needs.Β 

Micronutrient Testing: The Micronutrient Test by SpectraCell Laboratories offers a comprehensive assessment of essential vitamins, minerals, antioxidants, fatty acids, and amino acids, including magnesium. This test provides a detailed evaluation of both extracellular (outside cells) and intracellular (inside cells) micronutrient levels.

Can Adequate Magnesium Come From the Diet?

Adequate magnesium levels can generally be achieved through a well-balanced, well-considered diet. The Recommended Dietary Allowance (RDA) for magnesium varies and may not be sufficient for many people's needs: adult men are said to minimally require about 400-420 mg per day, while adult women are said to require approximately 310-320 mg. Foods rich in magnesium include leafy green vegetables like spinach, nuts and seeds such as pumpkin seeds and almonds, along with whole grains and legumes such as beans and lentils, and certain fish, including salmon. Including a variety of these foods in your daily diet can help you meet your magnesium needs.

How Much Magnesium to Take

Magnesium supplementation is often considered when dietary intake is insufficient or in certain health conditions. The recommended dose can vary significantly depending on individual factors such as age, gender, and specific health needs. The recommended supplement dose varies based on age, gender, and individual health needs. The accepted dosages for magnesium supplementation are 65 mg/day for children ages 1-3, 110 mg/day for children ages 4-8, and 350 mg/day for adults and children ages nine and up.

[signup]

Magnesium for Joint Health: Key Takeaways

Magnesium deficiency can contribute to joint discomfort due to its key role in muscle function, bone health, nerve regulation, and anti-inflammatory properties. Ensuring adequate magnesium intake is crucial for muscle contraction and relaxation, energy production in muscle cells, and supporting the reduction of inflammation, all of which can help alleviate joint discomfort. By supporting bone health and the synthesis of essential structural proteins, magnesium also enhances joints' overall integrity and function. Therefore, adequate magnesium levels are vital for healthy muscles and joints, significantly reducing musculoskeletal discomfort and improving mobility.

The information in this article is designed for educational purposes only and is not intended to be a substitute for informed medical advice or care. This information should not be used to diagnose or treat any health problems or illnesses without consulting a doctor. Consult with a health care practitioner before relying on any information in this article or on this website.

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Lab Tests in This Article

1. Al Alawi, Abdullah M., et al. β€œMagnesium and Human Health: Perspectives and Research Directions.” International Journal of Endocrinology, vol. 2018, no. 1, 2018, pp. 1–17, www.ncbi.nlm.nih.gov/pmc/articles/PMC5926493/.

2. Bertagna, Brittney . β€œMagnesium for Diabetes: Uncovering Its Role in Metabolic Health.” Rupa Health, 29 Nov. 2023, www.rupahealth.com/post/magnesium-for-diabetes-uncovering-its-role-in-metabolic-health.

3. Botturi, Andrea, et al. β€œThe Role and the Effect of Magnesium in Mental Disorders: A Systematic Review.” Nutrients, vol. 12, no. 6, 3 June 2020, p. 1661, https://doi.org/10.3390/nu12061661.

4. Carvil, Phil, and John Cronin. β€œMagnesium and Implications on Muscle Function.” Strength and Conditioning Journal, vol. 32, no. 1, Feb. 2010, pp. 48–54, https://journals.lww.com/nsca-scj/fulltext/2010/02000/magnesium_and_implications_on_muscle_function.7.aspx

5. Chi, Zhe, et al. β€œMicrobial Biosynthesis and Secretion Ofl-Malic Acid and Its Applications.” Critical Reviews in Biotechnology, vol. 36, no. 1, 15 July 2014, pp. 99–107, https://doi.org/10.3109/07388551.2014.924474

6. Cloyd, Jaime. β€œThe Top 6 Essential Health Benefits of Magnesium That You Should Know.” Rupa Health, 18 Oct. 2023, www.rupahealth.com/post/the-top-6-therapeutic-uses-of-magnesium-you-need-to-know.

7. DiSilvestro, Robert A, et al. β€œMagnesium Glycinate Supplementation in Bariatric Surgery Patients and Physically Fit Young Adults.” The FASEB Journal, vol. 27, no. S1, Apr. 2013, https://doi.org/10.1096/fasebj.27.1_supplement.lb291.

8. Havelin, Joshua, and Tamara King. β€œMechanisms Underlying Bone and Joint Pain.” Current Osteoporosis Reports, vol. 16, no. 6, 29 Oct. 2018, pp. 763–771, https://doi.org/10.1007/s11914-018-0493-1.

9. Kirkland, Anna, et al. β€œThe Role of Magnesium in Neurological Disorders.” Nutrients, vol. 10, no. 6, 6 June 2018, p. 730, www.ncbi.nlm.nih.gov/pmc/articles/PMC6024559/.

10. Kuang, Xiaoqing, et al. β€œMagnesium in Joint Health and Osteoarthritis.” Nutrition Research, vol. 90, 1 Apr. 2021, www.sciencedirect.com/science/article/pii/S0271531721000142, https://doi.org/10.1016/j.nutres.2021.03.002.

11. Maulood, I.M. et al. β€œRoles of Magnesium Ions in Vascular Relaxation via Calcium Channel and Cyclooxygenase Pathway in Isolated Rat Aorta.” ZANCO Journal of Pure and Applied Sciences, vol. 29, no. 3, 15 Aug. 2017, https://doi.org/10.21271/zjpas.29.3.7.Β 

12. Na, Hyo-Seok, et al. β€œThe Role of Magnesium in Pain.” PubMed, University of Adelaide Press, 2011, www.ncbi.nlm.nih.gov/books/NBK507245/.

13. National Institutes of Health. β€œOffice of Dietary Supplements - Magnesium.” National Institutes of Health, 2016, https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/

14. Potter, J. D., et al. β€œMagnesium and the Regulation of Muscle Contraction.” Federation Proceedings, vol. 40, no. 12, 1 Oct. 1981, pp. 2653–2656, pubmed.ncbi.nlm.nih.gov/7286246/.

Preston, JheriAnne . β€œFunctional Medicine Strategies for Managing Joint Pain in Cold Weather.” Rupa Health, 18 Dec. 2023.

15. Russell, I. J., et al. β€œTreatment of Fibromyalgia Syndrome with Super Malic: A Randomized, Double Blind, Placebo Controlled, Crossover Pilot Study.” The Journal of Rheumatology, vol. 22, no. 5, 1995, pp. 953–958, https://pubmed.ncbi.nlm.nih.gov/8587088/

16. Schwalfenberg, Gerry K., and Stephen J. Genuis. β€œThe Importance of Magnesium in Clinical Healthcare.” Scientifica, vol. 2017, 28 Sept. 2017, pp. 1–14, www.ncbi.nlm.nih.gov/pmc/articles/PMC5637834/, https://doi.org/10.1155/2017/4179326.

17. Souza, A.C.R. , et al. β€œThe Integral Role of Magnesium in Muscle Integrity and Aging: A Comprehensive Review.” Nutrients, vol. 15, no. 24, 16 Dec. 2023, pp. 5127–5127, https://doi.org/10.3390/nu15245127.Β 

18. Tangvoraphonkchai, Kamonwan, and Andrew Davenport. β€œMagnesium and Cardiovascular Disease.” Advances in Chronic Kidney Disease, vol. 25, no. 3, May 2018, pp. 251–260, https://doi.org/10.1053/j.ackd.2018.02.010.

19. Vazquez, Kate. β€œThis Is How Much Magnesium You Should Take Based on Your Age.” Rupa Health, 9 Sept. 2022, www.rupahealth.com/post/magnesium-101.

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