Patient Care
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April 3, 2025

CT Scan vs. MRI: Understanding the Key Differences and When to Use Each

Medically Reviewed by
Updated On
April 3, 2025

Medical imaging has revolutionized how we diagnose and monitor health conditions. Two of the most common imaging techniques are computed tomography (CT) scan and magnetic resonance imaging (MRI). 

Though both create detailed images of the inside of the body, they work differently and are used for different purposes. This article explains the main differences between CT and MRI and when each is used.

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What Are CT and MRI Scans?

Knowing how each scan works is helpful for understanding which is best for a specific situation.

Computed Tomography (CT) Scan

A computed tomography (CT) scan, or CAT scan, uses a series of X-ray images taken from different angles and a computer to create cross-sectional pictures of the body—almost like slices through a loaf of bread. These images provide excellent detail of bones, blood vessels, and specific organs.

CT is commonly used in emergency situations because it’s fast, widely available, and effective at detecting issues like:

  • Bleeding in the brain
  • Lung diseases
  • Abdominal injuries
  • Bone fractures and spine problems
  • Certain cancers

However, repeated exposure should be avoided unless necessary because it uses ionizing radiation. Sometimes, a contrast dye is used to improve the visibility of blood vessels and organs.

Magnetic Resonance Imaging (MRI)

A magnetic resonance imaging (MRI) scan uses powerful magnets and radio waves to generate highly detailed images of the body’s internal structures. Unlike CT, it does not use radiation, making it a safer option for repeated use.

MRI is ideal for looking at:

  • The brain and spinal cord
  • Joints and soft tissues (like muscles and tendons)
  • Heart and blood vessels
  • Abdominal organs (e.g., liver, kidneys, uterus)

Because MRI scans take longer to perform (20–60 minutes) and require patients to lie still in a narrow tube, they can be challenging for those with claustrophobia or who have trouble staying still. 

Also, people with metal implants or pacemakers may not be able to have an MRI unless the device is MRI-compatible. Inform your healthcare team about any implanted devices.

Key Differences Between CT and MRI

Knowing how CT and MRI differ in technology, safety, speed, and cost can help patients and healthcare providers make informed decisions based on the clinical situation and individual needs.

Technology and Safety

CT uses ionizing radiation in the form of X-rays to take detailed pictures of the body from multiple angles. A computer processes the images to create cross-sectional "slices" of organs, bones, or tissues. While CT scans are generally safe, repeated exposure to radiation—especially in young patients—should be minimized unless medically necessary.

MRI, conversely, uses strong magnetic fields and radio waves to produce highly detailed images without any radiation. This makes it a safer choice for patients who require frequent imaging or for populations more sensitive to radiation, such as children or pregnant individuals (when deemed safe by their healthcare provider).

However, MRI has limitations. It is unsuitable for patients with certain metal implants or electronic devices, such as older pacemakers, cochlear implants, or some types of surgical clips, unless those devices are specifically labeled MRI-compatible. 

Speed and Accessibility

With regard to the speed of the scan:

  • CT scans are typically much faster, with most completed in just a few minutes. This makes CT the preferred option in emergency situations—such as trauma, suspected stroke, or internal bleeding—where every second counts.
  • MRI scans take longer, usually between 20 to 60 minutes, depending on the body part and the level of detail needed. The patient must lie still during the scan, which can be difficult for some, especially young children or those with claustrophobia.

In terms of availability:

  • CT scanners are more commonly found in emergency rooms and community hospitals. 
  • MRI machines are available in most large hospitals and imaging centers, but scheduling can take longer, and appointments may be limited, especially in rural areas.

Cost Considerations

In general, an MRI is more expensive than a CT scan. This is due to the higher cost of equipment, longer scan time, and more detailed imaging capabilities. The price difference can vary significantly based on geographic location, facility type, and whether contrast agents are used.

Insurance coverage for CT and MRI varies, depending on the reason for the scan and the insurance provider. Patients should always check with their provider to understand their out-of-pocket costs and whether prior authorization is required.

When to Use Each Imaging Test

CT and MRI are both non-invasive, powerful tools, but each is better suited to certain conditions. Choosing the right scan depends on the type of tissue being examined, the urgency of the situation, and the patient’s overall health.

When CT Is Preferred

CT scans are often the first choice in emergencies because they are fast and widely accessible. They are especially helpful for detecting:

  • Trauma-related injuries: including skull fractures, internal bleeding, and broken bones
  • Lung conditions: such as pneumonia, pulmonary embolism, or lung cancer
  • Abdominal pain: to identify causes like appendicitis, kidney stones, or bowel blockages
  • Cancers: for detecting tumors, staging disease, and monitoring treatment
  • Cardiac imaging: CT angiography can assess blood vessels and coronary artery disease.

Because CT offers excellent detail of bone and air-filled spaces, it’s ideal for imaging the chest, sinuses, and skeletal system. 

When MRI Is Better

MRI provides exceptional detail of soft tissues, making it ideal for conditions where CT may not give enough information. It is often used to evaluate:

  • Brain and spinal cord: to detect strokes, tumors, multiple sclerosis, or nerve damage
  • Joints and ligaments: such as torn ACLs, meniscus injuries, or rotator cuff tears
  • Muscles and tendons: for sports injuries or chronic pain
  • Abdominal and pelvic organs: including liver, kidneys, uterus, ovaries, and prostate
  • Heart function: MRI can assess cardiac structure, function, and inflammation

MRI is typically used in non-emergency settings, where high-resolution soft tissue imaging is needed, and there’s time to plan the scan. It's also helpful when CT results are unclear or when avoiding radiation is important—such as in children or pregnant patients (when medically appropriate).

Special Considerations

While CT and MRI are widely used, specific patient populations and clinical scenarios require extra consideration when choosing the most appropriate imaging method.

Pediatric Patients

In children, imaging decisions must balance diagnostic value with safety. MRI is often preferred because it doesn’t use radiation. However, because MRI scans take longer and require stillness, younger children may need sedation to complete the scan successfully. CT is sometimes chosen in urgent cases because it is faster and easier to perform.

Patients with Claustrophobia

MRI machines are long, narrow tubes; the scan can last 30 minutes or more. For patients with claustrophobia or anxiety, this can be uncomfortable or even intolerable. In such cases, options may include:

  • Open MRI (if available)
  • Pre-scan sedation
  • Choosing CT when clinically acceptable, especially for less complex imaging needs

CT scans are more open and take just a few minutes, making them more tolerable for anxious patients.

Use of Contrast Agents

Both CT and MRI may involve contrast agents to enhance the visibility of blood vessels, tumors, or inflammation.

  • CT contrast contains iodine and is generally safe but may affect kidney function in patients with kidney disease or dehydration.
  • MRI contrast (gadolinium-based) is typically well tolerated, but patients with severe kidney disease may need special screening.

Side Effects of Contrast

While most people tolerate contrast material without issues, a small number may experience side effects, especially with iodine-based contrast agents commonly used in CT scans.

Mild Reactions (more common):

  • Nausea or vomiting
  • Headache
  • Itching or flushing
  • Mild skin rash or hives

Moderate to Severe Reactions (less common but serious):

  • Severe rash or widespread hives
  • Wheezing or difficulty breathing
  • Swelling of the tongue or throat
  • Abnormal heart rhythms
  • Very low blood pressure (hypotension)

Seek immediate medical attention if you experience these or other symptoms after a contrast-enhanced scan.

Before your scan, always inform your provider if you:

  • Have any allergies, especially to contrast dyes
  • Have a history of kidney problems
  • Have ever had a reaction to contrast material in the past

This helps ensure your imaging is as safe and comfortable as possible.

Accessibility and Scheduling

CT scanners are typically more widely available and easier to schedule, especially in emergency departments or rural areas. MRI machines are often found in larger hospitals or specialized imaging centers, and wait times may be longer.

Providers should consider the urgency of diagnosis, local resources, and patient needs when recommending a scan.

Healthcare providers choose the appropriate imaging test based on the patient’s condition, clinical judgment, and available resources.

Emerging Technologies and Advancements

Medical imaging continues to evolve, offering faster, safer, and more precise ways to diagnose disease. For example:

In CT technology, newer scanners offer:

  • Lower radiation doses with improved image quality
  • Faster scan speeds, reducing the need for breath-holding or sedation
  • Dual-energy CT, which uses two different X-ray energy levels to better differentiate tissue types (e.g., kidney stones vs. uric acid)

MRI advancements include:

  • Faster scanning sequences to reduce scan time and improve comfort
  • Higher-resolution imaging for detecting smaller abnormalities
  • Functional MRI (fMRI), which maps brain activity in real-time
  • AI-assisted image reconstruction, which enhances clarity and reduces scan artifacts

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Key Takeaways

  • CT scans use X-rays, making them faster and ideal for emergencies, bone injuries, and lung conditions—but they do involve radiation exposure.
  • MRI uses magnetic fields and radio waves, offering detailed images of soft tissues like the brain, joints, and organs—without any radiation.
  • CT is more widely available and quicker, often taking only a few minutes, while MRI takes longer and may not be suitable for patients with certain implants or claustrophobia.
  • Due to the absence of radiation, MRI is typically safer for repeated imaging, especially in children or those needing long-term follow-up.
  • CT is commonly used in trauma, stroke, and cancer staging, while MRI is preferred for neurological, musculoskeletal, and soft tissue evaluations.
  • MRI is usually more expensive than CT, and insurance coverage may vary—always check with your provider.
  • Advancements in both technologies—like low-dose CT, faster MRI sequences, and AI image enhancement—improve safety, comfort, and diagnostic accuracy.
The information in this article is designed for educational purposes only and is not intended to be a substitute for informed medical advice or care. This information should not be used to diagnose or treat any health problems or illnesses without consulting a doctor. Consult with a health care practitioner before relying on any information in this article or on this website.

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Bryant, A. (2025, February 12). Pulmonary embolism: Causes, symptoms and treatment. Rupa Health. https://www.rupahealth.com/post/pulmonary-embolism-causes-symptoms-and-treatment

Cloyd, J. (2023, September 28). A Holistic Functional Medicine Protocol For Multiple Sclerosis. Rupa Health. https://www.rupahealth.com/post/a-holistic-functional-medicine-protocol-for-multiple-sclerosis

E Behluli, Preuer, H. M., N Schiefermeier-Mach, Hornung, R., M Küchler, & M Prokopetz. (2024). Patient-centric comparative analysis of experiences in open upright and conventional closed MRI scanners. Radiography, 30(5), 1258–1264. https://doi.org/10.1016/j.radi.2024.06.021

Feger, J. (2024, October 3). Dual-energy CT. Radiopaedia; Radiopaedia.org. https://radiopaedia.org/articles/dual-energy-ct-4?lang=us

Glover, G. H. (2011). Overview of Functional Magnetic Resonance Imaging. Neurosurgery Clinics of North America, 22(2), 133–139. https://doi.org/10.1016/j.nec.2010.11.001

Ibrahim, M. A., & Dublin, A. B. (2019, April 30). Magnetic Resonance Imaging (MRI), Gadolinium. National Library of Medicine; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK482487/

Kim, Y.-H., Choi, M., & Kim, J.-W. (2019). Are titanium implants actually safe for magnetic resonance imaging examinations? Archives of Plastic Surgery, 46(1), 96–97. https://doi.org/10.5999/aps.2018.01466

Küstner, T., Qin, C., Sun, C., Ning, L., & Scannell, C. M. (2024). The intelligent imaging revolution: artificial intelligence in MRI and MRS acquisition and reconstruction. Magnetic Resonance Materials in Physics Biology and Medicine. https://doi.org/10.1007/s10334-024-01179-2

Lawal, O., P. Regelous, & D. Omiyi. (2024). Supporting claustrophobic patients during magnetic resonance imaging examination– the radiographer perspective. Radiography, 30(1), 80–86. https://doi.org/10.1016/j.radi.2023.10.011

National Institute of Biomedical imaging and Bioengineering. (2019, July 17). Magnetic Resonance Imaging (MRI). National Institute of Biomedical Imaging and Bioengineering. https://www.nibib.nih.gov/science-education/science-topics/magnetic-resonance-imaging-mri

National institute of biomedical imaging and bioengineering. (2022, June). Computed Tomography (CT). National Institute of Biomedical Imaging and Bioengineering. https://www.nibib.nih.gov/science-education/science-topics/computed-tomography-ct

Radiological Society of North America (RSNA) and American College of Radiology (ACR). (2018). Contrast Materials. Radiologyinfo.org. https://www.radiologyinfo.org/en/info/safety-contrast

Radiology (ACR), R. S. of N. A. (RSNA) and A. C. of. (2020, June 15). Body CT. Radiologyinfo.org. https://www.radiologyinfo.org/en/info/bodyct

Zghaib, T. (2024). Current State of MRI With Cardiac Devices - American College of Cardiology. American College of Cardiology. https://www.acc.org/latest-in-cardiology/articles/2024/05/21/10/30/current-state-of-mri-with-cardiac-devices#resources-for-article

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