Medication Fact Sheets
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November 22, 2024

Best Time to Take Lexapro for Anxiety

Medically Reviewed by
Updated On
November 26, 2024

You're not alone if you're feeling overwhelmed, anxious, or just not quite yourself. Many people experience times when life feels heavy, and it can be hard to know where to turn. Remember, asking for help is a brave step, and for some, that means finding support through medication like Lexapro.

Lexapro, also known as escitalopram, is commonly prescribed to help manage anxiety and depression. While it can be an important part of feeling better, it’s just one step to reclaim balance and well-being. This article explores how Lexapro works, how to use it effectively, and tips for finding the best routine for your needs.

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What Is Lexapro and How Does It Work for Anxiety?

Lexapro helps manage anxiety by increasing serotonin levels, a neurotransmitter that regulates mood and emotional well-being. It is classified as a Selective Serotonin Reuptake Inhibitor (SSRI), which blocks serotonin reabsorption in the brain. 

Typically, serotonin is released into the brain's synapses, where it helps send signals between nerve cells. Then, it is typically reabsorbed by the nerve cells that released it. By blocking this reabsorption, Lexapro allows more serotonin to remain in the brain, helping stabilize mood and reduce anxiety. This can ease feelings of fear, nervousness, and overwhelm, which are common in anxiety disorders.

Common Reasons for Prescribing Lexapro

Lexapro is often prescribed for generalized anxiety disorder (GAD), panic disorder, and other anxiety-related conditions like social anxiety or obsessive-compulsive disorder (OCD). It can also help address mood issues that often accompany anxiety, such as irritability and depression.

Typical Onset of Action

Lexapro typically takes 1-4 weeks to take full effect. During this time, your body adjusts to the medication, and noticeable changes may take a little while. Some individuals may experience slight improvements in mood or anxiety within the first few days, but it’s important to allow the medication time to work. The gradual increase in serotonin helps create lasting improvements in mood and anxiety.

Regular follow-ups with your doctor will help monitor progress, address any side effects, and adjust the dosage if needed.

Morning vs. Evening: Understanding the Best Time to Take Lexapro

Choosing the right time of day to take Lexapro can impact how well you tolerate the medication and its side effects.

Morning Dosing Benefits

Taking Lexapro in the morning can help reduce the risk of insomnia, a common side effect. Morning dosing may also help you stay more alert during the day and can be easier to remember as part of your daily routine.

Evening Dosing Benefits

Evening dosing may be ideal for those who experience drowsiness or nausea after taking Lexapro. Taking the medication at night allows these side effects to occur while you sleep, so you wake up feeling more refreshed. Evening dosing can also be helpful for those who may struggle to remember to take it in the morning.

Key Factors to Consider

Consider how morning or evening dosing will affect your productivity and sleep. It's important to choose a time that fits into your routine and is easy to stick to consistently. 

Factors That Influence the Best Time to Take Lexapro

The best time to take Lexapro depends on factors like your daily routine, lifestyle, and how your body responds to the medication.

Lifestyle and Daily Routine

The timing of Lexapro can depend on your work schedule, meals, and exercise routine. Morning doses may help enhance energy, while evening doses may reduce side effects. Taking Lexapro with meals can ease stomach irritation, and adjusting your dose around workouts can help manage side effects like fatigue or dizziness. Aligning your dosing with your daily routine can maximize its effectiveness and minimize discomfort.

Side Effect Management

Lexapro may cause side effects like fatigue, insomnia, and nausea. Adjusting the timing of your dose can help manage these. Taking it in the evening can reduce drowsiness, while morning dosing may help avoid sleep disturbances. Taking it with food can also ease nausea.

Interactions with Other Medications or Supplements

Be mindful of potential interactions with other medications, herbs, and supplements. When combined with Lexapro, over-the-counter medications like NSAIDs can increase the risk of bleeding. Additionally, St. John's Wort can interfere with its effectiveness and increase the risk of serotonin syndrome. Consult your healthcare provider for guidance on timing to ensure Lexapro is used safely with other treatments.

Consulting with Healthcare Providers

Discuss the best time to take Lexapro with your doctor or pharmacist. They can help personalize your dosing schedule to ensure its effectiveness and well-toleration.

Tips for Finding the Right Schedule for Taking Lexapro

Finding the right time to take Lexapro may take some trial and error. Here are some tips to help you find the best schedule.

  1. Start with the prescribed schedule: Follow your healthcare provider’s initial guidance for proper use before making any changes.

  2. Keep a medication diary: Track your mood, side effects, and overall well-being for at least two weeks. This can help identify patterns and determine if adjustments to the timing are necessary. You can use various apps or download templates to make this easier.

  3. Gradually adjust the timing if necessary: With your doctor’s guidance, adjust your dosing time in small increments to find the best fit.

  4. Stay consistent: Take Lexapro at the same time each day to maintain steady levels and improve effectiveness. Setting a phone reminder can help ensure you stay on track.

Frequently Asked Questions About Lexapro Timing

Here are answers to common questions about Lexapro timing and usage.

Can I Switch from Morning to Evening?

Yes, you can switch from morning to evening dosing, but it’s best to do so gradually to give your body time to adjust. Consult your doctor for guidance on how to do this to minimize potential side effects.

What Happens If I Miss a Dose?

If you miss a dose of Lexapro, take it as soon as you remember unless it’s almost time for your next dose. In that case, skip the missed dose and take your next dose as scheduled. Do not double up on doses. If you miss doses frequently or are unsure how to handle a missed dose, consult with your doctor.

Can Timing Affect Lexapro’s Effectiveness?

Timing does not affect Lexapro's overall effectiveness. However, taking it at the right time can help manage side effects. Finding a time that works best for your lifestyle and how your body responds can make it easier to stick to your medication plan.

Safety Considerations and Side Effects

When taking Lexapro, it's important to be mindful of potential side effects and follow safety guidelines.

Common Side Effects Based on Timing

Side effects can vary with timing. Morning dosing may increase energy but could also heighten anxiety. Evening dosing can help reduce insomnia and nausea but may cause drowsiness or fatigue. Adjusting the timing can help you manage these effects more comfortably.

Warning Signs to Watch For

If you experience worsening anxiety or depression, severe fatigue, significant mood changes, or persistent insomnia, contact your healthcare provider immediately.

Importance of Gradual Dosage Adjustments

Do not adjust your dosage or stop taking Lexapro abruptly without consulting your doctor. Stopping Lexapro suddenly can result in SSRI (or antidepressant) discontinuation syndrome.  Symptoms include: 

  • Physical symptoms: Headaches, dizziness, nausea, vomiting, lightheadedness, tiredness, and/or flu-like symptoms. 
  • Psychological symptoms: Anxiety, irritability, agitation, aggression, insomnia, and vivid dreams 
  • Sensory disturbances: Blurry vision, burning sensations, and shock 

Gradual changes help minimize side effects and maintain the medication’s effectiveness.

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Key Takeaways

  • The best time to take Lexapro depends on factors like side effects, your lifestyle, and how your body responds to the medication.
  • Consider your daily routine and personal preferences to identify the optimal dosing time.
  • By adjusting your medication schedule with your doctor’s approval, you can take an active role in managing your anxiety and improving your overall well-being.
The information provided is not intended to be a substitute for professional medical advice. Always consult with your doctor or other qualified healthcare provider before taking any dietary supplement or making any changes to your diet or exercise routine.

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