Women's Health
|
February 20, 2025

Are You Allergic to Your Copper IUD?

Written By
Erin Coleman RD
Medically Reviewed by
Updated On
February 26, 2025

Exposure to copper is fairly common, but research data suggests an average of nearly 4% of people exposed to copper have allergic reactions upon testing. 

Copper IUDs are highly effective, hormone-free birth control options that use copper to prevent pregnancies. While they're a go-to for many women, some individuals report symptoms that may be linked to allergic reactions.

The good news is that reactions caused by copper IUDs are somewhat rare. This article explores the causes, symptoms, and management strategies for allergies to copper IUDs, helping impacted individuals make informed decisions about their health and well-being.

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What is a Copper IUD?

Copper intrauterine devices (IUDs) are tiny, T-shaped, long-term birth control devices containing a coiled copper wire. A healthcare provider inserts it into a woman's uterus to significantly reduce the risk of a pregnancy. 

These IUDs release copper into the uterus, preventing pregnancies without hormones. Copper IUDs affect sperm movement and function, reducing the chance of sperm reaching the uterus and fertilizing an egg.

Paragard® is the only copper IUD available in the U.S. (The United Kingdom, Canada, and other countries offer additional options). It can prevent pregnancies for up to 10 years

Less than 1% of women using these IUDs get pregnant within the first year of use. A specialist can remove it at any time. But despite its many advantages, a copper IUD isn't for everyone.

Understanding Allergic Reactions

Becoming familiar with common reactions to copper helps establish if you're allergic to your copper IUD.

What Constitutes an Allergic Reaction?

An allergic reaction is the immune system's response to an allergen or foreign object, such as an IUD containing copper. Common medical devices that may cause allergic reactions include:

  • Cardiac electronic implants
  • Copper intrauterine devices (IUDs)
  • Endovascular stents
  • Surgical tissue adhesives
  • Blood pressure cuffs
  • FFP2 masks
  • Gloves
  • Medical adhesives
  • Medical devices for diabetics

Discussing potential allergies with a healthcare provider can help guide safer choices.

Specific Allergens in Copper IUDs

In addition to the copper itself as a potential allergen in non-hormonal IUDs, other parts of the IUD —- such as polyethylene and barium sulfate — may cause reactions in some women. 

Symptoms of Copper IUD Allergies

Learning more about copper IUD allergy symptoms can help you detect potential reactions and seek medical care when necessary.

Common Symptoms

Symptoms of copper IUD allergic reactions may include:

  • Skin rash
  • Itching
  • Flushing
  • Dermatitis 
  • Hives
  • Face, tongue, lip, or throat swelling

Some individuals report systemic symptoms, including fatigue, irritability, depression, hair loss, and skin problems. Others may develop nausea, vomiting, a drop in blood pressure, or difficulty breathing. 

More research is needed to investigate the systemic nature of these reactions.

Differentiating Allergic Reactions from Other IUD Side Effects

It's essential to understand other symptoms sometimes caused by copper IUDs (in addition to allergic reactions). Examples include:

  • Longer periods
  • Heavier periods
  • Menstrual cramps
  • Painful periods
  • Spotting between periods
  • Back pain
  • Irregular periods
  • Muscle cramping

These symptoms may ease up within 3-6 months of IUD insertion. 

Contact a healthcare provider as soon as possible if you experience any of the following:

  • Signs of an allergic reaction
  • Heavy bleeding
  • Pain during sex
  • Fever
  • Pelvic or abdominal pain
  • Trouble passing urine
  • Painful urination
  • Bleeding before or after sexual intercourse
  • Faintness
  • Lightheadedness
  • Falls
  • Weakness
  • Difficulty breathing
  • Vaginal pain, sores, or irritation
  • Unusual vaginal itching, odor, or discharge

When in doubt, contact your healthcare specialist to determine the cause of your symptoms and if they warrant further investigation. 

Diagnosing a Copper IUD Allergy

Diagnosing a copper IUD allergy typically entails the following:

Medical Evaluation Process

A review of a patient's medical history, physical exam, and symptoms assessment is critical to determine if they may have a copper IUD allergy. Patch testing is a common screening method for copper reactions and similar allergies.

During patch testing, small amounts of potential allergens are applied to the skin via patches. If an allergen is present, the skin reacts to these patches within hours or days. Patches should be left on the skin for at least 48 hours or as directed by a healthcare professional. 

Signs of allergic skin reactions to patch testing include soreness, redness, or itchiness at the skin's surface. 

Alternative Diagnostic Approaches

Consider alternative diagnostic approaches to determine if copper IUDs are the root cause of bothersome symptoms. Some healthcare providers may recommend a trial removal of the IUD to see if symptoms disappear before reintroducing the IUD. 

Ultrasounds and other imaging procedures can screen for complications linked to IUDs—such as accidental pregnancy or improper device positioning. 

Managing Allergic Reactions

Managing allergic reactions linked to copper IUDs might include the following:

Immediate Management Strategies

Anti-allergy medications, healthy lifestyle habits, and other treatments can help manage symptoms of mild allergic reactions that aren't bothersome. 

A healthcare provider may evaluate the severity of the reaction before recommending removal. Severe allergic reactions warrant immediate removal of a copper-containing IUD.

Long-Term Management and Prevention

It's critical to choose the right IUD for your personalized needs. If you're not a candidate for copper IUDs because of an allergy or other reasons, hormonal IUDs and other birth control methods are available. 

You're likely not a candidate for copper IUDs if you:

  • Might be pregnant
  • Have fibroids, pelvic inflammatory disease (PID), or endometriosis
  • Have uterine or cervical cancer
  • Develop a vaginal or uterine infection
  • Contract an STD
  • Have a condition called Wilson's disease that causes copper buildup within body tissues

Providers can personalize birth control plans based on each patient's unique needs, medical history, lifestyle, and preferences. 

Ongoing medical monitoring is critical for women with copper-containing or other IUDs to ensure they remain in place without complications or alarming symptoms. 

Alternatives to Copper IUDs

Copper IUDs are just some of the numerous contraception options available. Examples of others include:

Hormonal IUDs

Hormonal IUDs, such as Mirena®,  don't contain copper—but they do use hormones that may also cause allergic reactions in some women. 

Examples of such reactions (similar to copper allergy reactions) include an itchy rash, hives, asthma, swelling, and anaphylaxis in rare cases. 

Like copper IUDs, hormonal IUDs are more than 99% effective in preventing pregnancies. However, they aren't for everyone. 

These IUDs can cause the following side effects

Contraindications for hormonal IUDs include:

  • History of cervical cancer
  • Uterine or breast cancer
  • Liver disease
  • Fibroids
  • Unexplained vaginal bleeding
  • Sexually transmitted infections (STIs)
  • Other pelvic infections

One study suggests that copper intrauterine devices might increase inflammatory microbes and deplete healthy vaginal bacteria more than hormonal birth control options.  

Non-IUD Contraceptive Methods

Women who must (or desire to) avoid IUDs may consider other birth control methods, such as barrier methods (condoms and diaphragms), natural family planning, pills, patches, vaginal rings, or shots. 

Permanent birth control (sterilization) is available to women who do not wish to become pregnant in the future.

Living with a Copper IUD Allergy

Real-life experiences and case studies involving individuals with copper IUD allergies include:

Personal Stories and Case Studies

One case study found that a 26-year-old woman with a copper IUD developed dermatitis on her arms. She had the IUD inserted two weeks before symptom onset. 

After the IUD was removed, however, her symptoms completely disappeared. Her patch test was positive when exposed to 5% copper sulfate. 

The same researchers reported additional symptoms in other cases, particularly eczematous rashes that completely resolved soon after the copper IUDs were removed.

Another case study showed that a copper IUD in a 32-year-old user caused widespread hives and swelling of the eyelids, labia minora, and labia majora. Diagnostic testing (patch testing) yielded copper sulfate positivity. 

An endometrial biopsy revealed vaginal and vulval inflammation and hyperplasia in the cervical canal. IUD removal caused symptom remission.

Support and Resources

Support groups and online communities can help you pinpoint the cause of unfavorable side effects linked to copper IUDs and other birth control methods—or determine which birth control option may be right for you. 

However, it's best to consult with a healthcare professional to make a final and informed decision about your personalized women's health treatment plan.

Helpful professional resources include: 

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Key Takeaways

  • While rare, copper IUD allergies are a concern in some women using this popular non-hormonal birth control method. 
  • Signs of a copper IUD allergic reaction include skin rash, itching, flushing, dermatitis, hives, and swelling. Common diagnostic techniques include patch testing, symptom review, physical exam, and elimination/reintroduction. Treatment involves managing symptoms or, in most cases, removing a reaction-causing copper IUD.
  • It's essential to make informed choices about your health and consult with a professional before deciding on the proper birth control method for your personalized needs. 
  • Consider reading related articles, subscribing to our newsletter, or leaving a comment below to share your experience with copper IUDs.
The information in this article is designed for educational purposes only and is not intended to be a substitute for informed medical advice or care. This information should not be used to diagnose or treat any health problems or illnesses without consulting a doctor. Consult with a health care practitioner before relying on any information in this article or on this website.

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Association, N. E. (2024, May 14). Common metals that trigger eczema. National Eczema Association. https://nationaleczema.org/blog/metals-trigger-eczema/

Brown, B. P., Feng, C., Tanko, R. F., Jaumdally, S. Z., Bunjun, R., Dabee, S., Happel, A.-U., Gasper, M., Nyangahu, D. D., Onono, M., Nair, G., Palanee-Phillips, T., Scoville, C. W., Heller, K., Baeten, J. M., Bosinger, S. E., Burgener, A., Passmore, J.-A. S., Heffron, R., & Jaspan, H. B. (2023). Copper intrauterine device increases vaginal concentrations of inflammatory anaerobes and depletes lactobacilli compared to hormonal options in a randomized trial. Nature Communications, 14(1), 499. https://doi.org/10.1038/s41467-023-36002-4

Christie, J. (2022, July 13). How to shrink fibroids naturally, according to research. Rupa Health. https://www.rupahealth.com/post/how-to-shrink-fibroids-naturally-according-to-research

Cleveland Clinic. (2018). What are hormonal IUDs? Cleveland Clinic. https://my.clevelandclinic.org/health/drugs/hormonal-iud-mirena

Cloyd, J. (2023a, March 29). Top 5 differential diagnosis for abdominal pain and how to treat with functional medicine. Rupa Health. https://www.rupahealth.com/post/top-5-differential-diagnoses-for-abdominal-pain-and-how-to-treat-with-functional-medicine

Cloyd, J. (2023b, July 19). A functional medicine menorrhagia protocol: Comprehensive testing, therapeutic diet, and supplements. Rupa Health. https://www.rupahealth.com/post/menorrhagia-protocol

Cloyd, J. (2023c, September 13). Integrative medicine for pelvic pain: A multidisciplinary approach to OB/GYN care. Rupa Health. https://www.rupahealth.com/post/integrative-medicine-for-pelvic-pain-a-multidisciplinary-approach-to-ob-gyn-care

Copper | rupa health. (2020). Rupa Health. https://www.rupahealth.com/biomarkers/copper

DeCesaris, L. (2023, January 25). How to support a healthy menstrual cycle. Rupa Health. https://www.rupahealth.com/post/how-to-support-a-healthy-menstrual-cycle

Fadiloglu, S., Dilbaz, B., Fadiloglu, E., & Dilbaz, S. (2018). Relationship between copper IUD complications and ultrasonographic findings. Archives of gynecology and obstetrics, 297(4), 989–996. https://doi.org/10.1007/s00404-018-4711-y

Fage, S. W., Faurschou, A., & Thyssen, J. P. (2014). Copper hypersensitivity. Contact Dermatitis, 71(4), 191–201. https://doi.org/10.1111/cod.12273

Gunnarsson, L., & Wemrell, M. (2022). On the verge between the scientific and the alternative: Swedish women's claims about systemic side effects of the copper intrauterine device. Public Understanding of Science, 32(2), 096366252211075. https://doi.org/10.1177/09636625221107505

Intrauterine copper contraceptive. (2023). Cleveland Clinic. https://my.clevelandclinic.org/health/drugs/24345-intrauterine-copper-contraceptive

Khakham, C. (2023, July 11). Integrative medicine approach to asthma: Testing, dietary interventions, and natural remedies. Rupa Health. https://www.rupahealth.com/post/integrative-medicine-approach-to-asthma-testing-dietary-interventions-and-natural-remedies

Kresge, K. (2023, February 21). An integrative medicine approach to depression. Rupa Health. https://www.rupahealth.com/post/an-integrative-medicine-approach-to-depression

Ledford, D. (2022). Intrauterine device reaction. Aaaai.org. https://www.aaaai.org/allergist-resources/ask-the-expert/answers/2022/intrauterine

Malani, S. (2023, May 2). Complementary and integrative testing, therapies, and treatment and recovery of breast cancer. Rupa Health. https://www.rupahealth.com/post/complementary-integrative-therapies-for-treatment-and-recovery-of-breast-cancer

Mayo Clinic. (2019a). Mirena (hormonal IUD) . Mayoclinic.org. https://www.mayoclinic.org/tests-procedures/mirena/about/pac-20391354

Mayo Clinic. (2019b). ParaGard (copper IUD) - mayo clinic. Mayoclinic.org. https://www.mayoclinic.org/tests-procedures/paragard/about/pac-20391270

Mayo Clinic. (2022, February 16). Birth control options: Things to consider. Mayo Clinic. https://www.mayoclinic.org/healthy-lifestyle/birth-control/in-depth/birth-control-options/art-20045571

Neibling, K. (2023, February 27). Integrative medicine treatment for headaches. Rupa Health. https://www.rupahealth.com/post/integrative-medicine-treatment-for-headaches

NIH. (n.d.). Contraception and Birth Control Resources. Https://Www.nichd.nih.gov/. https://www.nichd.nih.gov/health/topics/contraception/more_information/resources

ParaGard ® T380A intrauterine copper contraceptive. (n.d.). https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/018680s066lbl.pdf

ParaGard® (copper IUD). (2024, January 1). Cleveland Clinic. https://my.clevelandclinic.org/health/drugs/17741-paragard-copper-iud

Patch testing can find what's causing your rash. (2025). Www.aad.org. https://www.aad.org/public/diseases/eczema/types/contact-dermatitis/patch-testing-rash

Preston, J. (2022, September 26). Benefits and risks of the top 5 most common prescriptive birth control methods. Rupa Health. https://www.rupahealth.com/post/benefits-and-risks-of-the-top-5-most-common-prescriptive-birth-control-methods

Purello D’Ambrosio, E., Ricciardi, L., Isola, S., Gangemi, S., Cilia, M., Levanti, C., & Marcazzó, A. (1996). Systemic contact dermatitis to copper-containing IUD. Allergy, 51(9), 658–659. https://doi.org/10.1111/j.1398-9995.1996.tb02302.x

Siliotti, F., Caroti, S., Caroti, A., & Alborino, F. (1987). Considerazioni su di un caso di allergia a IUD medicato al rame [Allergy to a copper-medicated IUD: a case report]. Ginecologia clinica, 8(3), 197–200.

Sweetnich, J. (2023, April 5). Top 5 labs for patients experiencing hair loss. Rupa Health. https://www.rupahealth.com/post/top-5-labs-for-patients-experiencing-hair-loss

The American College of Obstetricians and Gynecologists. (2020). The American College of Obstetricians and Gynecologists - ACOG. Acog.org. https://www.acog.org/

Varanasi-Diaz , S. (2024, April 18). 5 key interactions with hormonal birth control you should know about. Rupa Health. https://www.rupahealth.com/post/5-key-interactions-with-hormonal-birth-control-you-should-know-about

Wagner, N. (2023). Contact allergy to medical devices. Allergo Journal International, 33. https://doi.org/10.1007/s40629-023-00276-3

Weinberg, J. L. (2023, September 18). Integrative dermatology approach to urticaria (hives). Rupa Health. https://www.rupahealth.com/post/integrative-dermatology-approach-to-urticaria-hives

Weinberg, J. L. (2024, February 13). Allergic skin reactions: A functional medicine approach to identifying and treating root causes. Rupa Health. https://www.rupahealth.com/post/allergic-skin-reactions-a-functional-medicine-approach-to-identifying-and-treating-root-causes

Wilson, E. (2024, September 23). Patch testing for eczema: How it works and what it can diagnose. Rupa Health. https://www.rupahealth.com/post/patch-testing-for-eczema-how-it-works-and-what-it-can-diagnose

Wöhrl, S., Hemmer, W., Focke, M., Manfred Götz, & Reinhart Jarisch. (2001). Copper allergy revisited. Journal of the American Academy of Dermatology, 45(6), 863–870. https://doi.org/10.1067/mjd.2001.117729

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