Women's Health
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April 11, 2025

10 Best Supplements for Perimenopause Weight Management

Medically Reviewed by
Updated On
April 21, 2025

Weight gain during perimenopause can feel like an unexpected struggle. Despite eating healthy and staying active, many women find that their bodies change in unexpected ways. Hormonal shifts during this phase can impact how your body responds to food, exercise, and stress.

This article explores 10 supplements that may support weight management during perimenopause, offering natural options to help your body ease into this new chapter of life.

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Understanding Perimenopause and Weight Gain

Perimenopause is the transition leading up to menopause, typically beginning in a woman's 40s. During this time, hormone levels fluctuate, leading to various physical changes. These hormonal shifts can disrupt metabolism, making maintaining or losing weight harder, even with a healthy diet and regular exercise.

As estrogen levels decline, other hormones involved in regulating metabolism and fat storage are also affected, which can result in increased fat storage, particularly around the abdomen. Metabolism naturally slows during this phase, meaning the body burns fewer calories, making weight management even more challenging.

Along with weight gain, perimenopause often brings symptoms like hot flashes, sleep disturbances, mood swings, and fatigue, which can make it more challenging to stay active or maintain a balanced diet.

The Role of Supplements

Weight management during perimenopause involves unique changes due to hormonal fluctuations and metabolic shifts. However, with the right approach, it's possible to address these changes and maintain a healthy weight. Supplements may help by supporting hormone balance and providing essential nutrients that may be lacking during this phase.

A balanced diet, regular exercise, and appropriate supplements all play a role in managing weight during perimenopause. Supplements should complement, not replace, a healthy lifestyle and are most effective when combined with proper nutrition and physical activity.

When considering supplements, prioritize safety by selecting products that have been third-party certified for purity and effectiveness. This testing ensures the product contains the listed ingredients and is contaminant-free.

Before adding new supplements to your routine, consult your doctor to confirm they are safe, appropriate for your individual needs, and won't interact with any medications you may be taking.

10 Best Supplements for Perimenopause Weight Management

Perimenopause brings hormonal fluctuations that can affect weight. These supplements may promote overall well-being or health but are not intended to directly treat or prevent weight gain. 

Below are 10 supplements to consider for managing weight during this phase.

1. Vitamin D

Vitamin D is essential in metabolism and weight regulation by supporting the body's ability to use insulin and influencing fat storage. During perimenopause, many women experience a decline in vitamin D levels, which can impact overall health and weight management.

The recommended daily dosage for perimenopausal women is 2000 IU, although your doctor may recommend higher amounts based on your specific needs. Since vitamin D is fat-soluble, it's best taken with food to enhance absorption. Consider getting your levels tested to determine the most appropriate dosage.

Vitamin D can be obtained through sunlight, fortified foods like milk and cereals, and fatty fish like salmon. However, supplementation is often an effective way to ensure adequate levels.

2. Omega-3 Fatty Acids

Omega-3 fatty acids support the body's natural inflammatory response, which is often linked to weight gain. They also help improve insulin sensitivity, which makes weight management easier.

Aim for a balanced ratio of EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) for optimal benefits. Fish oil supplements are a common source, while plant-based options like flaxseeds and chia seeds provide ALA (alpha-linolenic acid), which the body can convert to EPA and DHA.

3. Probiotics

Research suggests gut health is linked to healthy weight by improving digestion and nutrient absorption. Hormonal changes during perimenopause can disrupt the gut microbiome.

Probiotics, particularly strains like Lactobacillus and Bifidobacterium, may support gut health and weight management. They can be found in fermented foods such as yogurt, kefir, and sauerkraut or taken as supplements.

4. Calcium and Magnesium

Calcium supports bone health, while magnesium helps regulate muscle function and blood sugar levels. Blood sugar fluctuations can influence hunger and cravings, making it more difficult to maintain portion control.

Taking calcium and magnesium together may enhance absorption. The typical dosage is around 1,000 to 1,200 mg of calcium and 320 mg of magnesium daily. Good sources include leafy greens, dairy, nuts, seeds, or supplements.

5. B-Complex Vitamins

B vitamins support energy metabolism and healthy nerve function, which can be affected during perimenopause. Deficiencies, especially in B6 and B12, can contribute to fatigue and mood swings.

B-complex supplements are commonly recommended to help with energy levels, while specific B vitamins, like B6, can also support mood regulation. Good food sources of B vitamins include whole grains, eggs, organic grass-fed meats, and leafy greens.

6. Fiber Supplements

Fiber helps regulate digestion and maintain healthy blood sugar levels. During perimenopause, it can relieve constipation, a common issue, and promote fullness, which may reduce overeating.

The recommended daily fiber intake for women under 50 is 25 grams, and for those over 50, it is 21 grams. Fiber supplements like psyllium husk or flaxseed are convenient options to help meet this goal. It's best to gradually increase fiber intake to avoid digestive discomfort.

7. Herbal Supplements

These herbs may help maintain a healthy weight during perimenopause:

  • Black Cohosh: Commonly used to relieve hot flashes and other menopause-related symptoms, it may assist in weight balance.
  • Maca Root: Known for balancing hormones, which may indirectly support weight management.
  • Green Tea Extract: Contains compounds like catechins, which may promote a healthy metabolism.

8. Adaptogenic Herbs

Adaptogens help the body adapt to stress, a common trigger for weight gain during perimenopause due to hormonal imbalances.

  • Ashwagandha: May reduce stress and help maintain healthy cortisol levels, which can support weight balance.
  • Rhodiola Rosea: Known to reduce fatigue and support metabolism.
  • Holy Basil: Believed to help regulate blood sugar and manage weight.

9. Collagen

Collagen is a protein essential for skin elasticity, joint health, and overall vitality. As collagen production decreases with age, it can contribute to visible signs of aging and joint discomfort. 

 The top three types of collagen include:

  • Type I: Found in skin, tendons, and bones; supports skin elasticity.
  • Type II: Located in cartilage; promotes joint mobility.
  • Type III: Found in skin, blood vessels, and organs; helps with tissue repair.

Collagen is available in several forms, including powder, capsules, and liquid. The most common and effective form is hydrolyzed collagen powder, which is easily absorbed by the body. It can also be conveniently added to smoothies, coffee, or other beverages

10. Vitamin E

Vitamin E is an antioxidant that supports cellular health and helps protect the body from oxidative stress. It may also help alleviate certain perimenopausal symptoms like hot flashes. Sources include nuts, seeds, and leafy vegetables or through supplementation.

Lifestyle Factors

Supplements can support perimenopausal health. However, they are most effective when combined with a healthy lifestyle. A balanced diet, regular exercise, stress management, quality sleep, and hydration are key to maximizing their benefits.

Balanced Nutrition

A perimenopausal diet is the foundation of health during this transition. Focus on whole foods rich in essential nutrients, including lean proteins, fiber, healthy fats, and various fruits and vegetables. These foods provide vitamins and minerals that help maintain hormonal balance and support weight regulation. Limiting processed foods, refined sugars, and alcohol can reduce inflammation and enhance overall health during this time.

Physical Activity

Regular exercise is vital for managing weight and supporting health during perimenopause. Strength training and cardiovascular exercises help balance hormones, improve metabolism, and preserve muscle mass, which naturally declines with age. Activities like yoga and Pilates improve flexibility, reduce stress, and promote joint health. A balanced exercise routine that includes cardio, strength, and flexibility is particularly beneficial during this phase.

Mind-Body Connection

Stress can worsen hormonal imbalances and contribute to weight gain, particularly around the abdomen. Managing stress is essential to maintaining hormonal balance. Mind-body techniques like meditation, deep breathing, journaling, and mindfulness can help regulate stress levels. Prioritizing activities that promote mental well-being supports overall health during perimenopause.

Quality Sleep

Sleep is essential for maintaining hormonal balance, reducing stress, and supporting a healthy weight. During perimenopause, disruptions such as insomnia or night sweats may occur. Establishing a consistent bedtime routine, creating a calming sleep environment, and avoiding stimulating activities before bed can help improve sleep quality. Addressing sleep disturbances can also support weight regulation, as poor sleep can affect hunger hormones and increase cravings.

Hydration 

Staying hydrated is a simple yet effective way to support weight balance. Proper hydration helps regulate metabolism, maintain energy, and control hunger. Thirst is often mistaken for hunger, which could lead to unnecessary snacking. Drinking water throughout the day can prevent overeating and support digestion. Herbal teas and water-rich foods like fruits and vegetables can contribute to overall hydration.

Personalized Approach to Supplement Use

Since every woman's body responds differently during perimenopause, a personalized supplementation plan is key to achieving the best results. To ensure your plan is tailored to your unique needs, consider the following:

  • Health History and Medications: When selecting supplements, your healthcare provider will consider your health history, current symptoms, and any medications you are taking. This helps create a personalized approach to supplementation that aligns with your specific needs.

  • Hormone Testing: Hormone levels can fluctuate significantly during perimenopause, and testing can provide important insights into how your body responds. Estrogen, progesterone, and other hormones may vary, influencing how you feel and how your body reacts to supplements.

  • Regular Monitoring: Regular check-ins with your healthcare provider ensure that your supplement plan continues to address any changes in symptoms and supports your overall health.

  • Tracking Progress: Pay attention to any changes in energy, weight, mood, or other symptoms as you begin taking supplements. Journaling these shifts will help you assess the effectiveness of your regimen. With the support of your healthcare provider, you can fine-tune your approach for the best possible results.

If you experience any unusual side effects or are considering combining multiple supplements, consult with your healthcare provider to ensure safety and effectiveness.

Frequently Asked Questions (FAQs)

Here are answers to some common questions about supplement use during perimenopause. 

How long does it take for supplements to work for perimenopausal weight gain?

The effects of supplements vary. Some women may see changes within weeks, while others may take a few months. Diet, exercise, and consistency also play key roles in their effectiveness.

Can supplements completely prevent weight gain during perimenopause?

Supplements can help with weight management but are unlikely to prevent weight gain entirely. Hormonal changes, lifestyle factors, and genetics contribute to weight changes during this time. A balanced approach that includes diet, exercise, stress management, and supplements offers the best results.

Are natural supplements always safe for perimenopausal women?

Natural supplements can be beneficial but are not always safe for everyone. They may interact with medications or underlying health conditions. 

How do I know if I'm in perimenopause?

Perimenopause is a transitional phase leading up to menopause, typically occurring in your 40s or early 50s. Symptoms include irregular periods, hot flashes, night sweats, mood swings, and changes in sleep patterns. If you're experiencing these symptoms, it could suggest perimenopause, but it's a good idea to confirm with your doctor.

Can men benefit from these supplements for weight management?

Some ingredients in perimenopausal supplements may aid metabolism, but these supplements are specifically designed for women. Men should consult their healthcare provider before using them, as supplements should be tailored to individual health needs.

Are there any supplements to avoid during perimenopause?

Some supplements, especially those affecting hormone levels or interacting with medications, may not be suitable during perimenopause. For example, soy isoflavones are sometimes used to manage symptoms, but research on their effectiveness remains inconclusive.

How do supplements interact with hormone replacement therapy (HRT)?

Certain supplements may interact with HRT. Some may influence estrogen or progesterone levels, potentially affecting HRT's effectiveness. Work with your healthcare provider to coordinate supplements and HRT for the best outcomes.

What's the difference between perimenopause and menopause supplements?

Perimenopause supplements are designed to address hormonal fluctuations and symptoms leading up to menopause. Menopause supplements focus on post-menopausal health, such as bone and heart health.

Can these supplements help with other perimenopausal symptoms?

Yes, many supplements support overall well-being during perimenopause, not just weight management. Some herbs and vitamins may help with hot flashes, sleep, stress, and mood. For a tailored approach, discuss your needs with your healthcare provider.

How often should I review my supplement regimen?

Your supplement regimen may need to be adjusted as your body's needs change. Reviewing your plan every few months or when you notice changes in your symptoms is helpful. Your doctor can assist in making necessary adjustments.

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Key Takeaways 

  • Maintaining a healthy weight during perimenopause is achievable through a whole-person care approach that includes a balanced diet, regular exercise, and a healthy lifestyle.
  • Supplements can complement this approach and support you during this transition. The top 10 supplements discussed are backed by research to aid weight management.
  • The most effective way to navigate perimenopause is to develop a personalized plan tailored to your unique needs, health history, and current medications. Work with your healthcare provider to determine the best approach for your health goals.
The information in this article is designed for educational purposes only and is not intended to be a substitute for informed medical advice or care. This information should not be used to diagnose or treat any health problems or illnesses without consulting a doctor. Consult with a health care practitioner before relying on any information in this article or on this website.

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