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Reference Guide
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Intact PTH
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Intact PTH

What's 
Intact PTH
?
Intact Parathyroid Hormone (PTH) is an important hormone made by your parathyroid glands, which are four tiny glands located behind your thyroid gland in your neck. Its main job is to control the levels of calcium and phosphate in your body. These two minerals are essential for the normal functioning of your cells, nerves, muscles, and bones. PTH does this by working on your kidneys, intestines, and bones, affecting how these organs absorb, release, or use calcium and phosphate. In simple terms, Intact PTH is like a careful manager, making sure your body keeps the right balance of these vital minerals for good health.
If Your Levels Are High
Elevated Intact PTH levels mean that your body is putting in extra effort to keep the right balance of calcium and phosphate. This can happen for various reasons, such as not getting enough calcium or vitamin D from your diet, or taking certain medications that affect how your body absorbs these minerals. Sometimes, high PTH levels can be a sign of hyperparathyroidism, which means your parathyroid glands are working too hard. This can be caused by harmless growths on the glands or a response to low calcium levels in your body. Remember, high PTH levels are a signal, not a disease, and figuring out the root cause can help get things back on track.
Symptoms of High Levels
Symptoms of high levels of Intact PTH could include fatigue, bone pain, muscle weakness, frequent urination, and in some cases, mood changes or depression.
If Your Levels are Low
Low levels of Intact PTH might mean that your body isn't making enough of this important hormone. This can happen for various reasons, such as not getting enough magnesium or vitamin D in your diet, which are both needed for PTH production. Another possible cause could be chronic kidney disease, since your kidneys play a key role in using and activating PTH. Some medications, like lithium and bisphosphonates, might also lower PTH levels. Keep in mind that these are just potential reasons and not definite diagnoses.
Symptoms of Low Levels
Symptoms of low levels of Intact PTH could include muscle cramps or spasms, numbness or tingling in the hands, feet, or lips, and fatigue. In severe cases, it could also lead to confusion or memory problems.

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