IgG2

Immunoglobulin G2

What's

IgG2

Immunoglobulin G2 (IgG2) is a type of antibody, which is a protein produced by your immune system. Antibodies are like your body's security team, always on the lookout for harmful invaders like bacteria and viruses. When these invaders are detected, antibodies spring into action, helping your body fight off the infection. IgG2 is one of the four subclasses of Immunoglobulin G (IgG), the most abundant type of antibody in your body. Each subclass has its own special abilities and responsibilities. IgG2, in particular, is known for its role in responding to certain types of bacteria, especially those with polysaccharide coatings. IgG2 is a key player in your immune system, helping to keep you healthy by warding off specific types of bacterial infections.

If Your Levels Are High

High levels of Immunoglobulin G2 (IgG2) in your body could suggest that your immune system is actively fighting off an infection. This is because IgG2 is a type of protein that your body produces more of when it's trying to defend against harmful invaders like bacteria or viruses. Alternatively, high IgG2 levels could also indicate an immune system disorder, such as an autoimmune disease where your body mistakenly attacks its own cells. Certain medications, like immunosuppressants or corticosteroids, can also affect IgG2 levels. It's important to note that while high IgG2 levels can provide clues about what's happening in your body, they are just one piece of the puzzle and should be considered alongside other tests and evaluations.

Symptoms of High Levels

Symptoms of high levels of IgG2 could include frequent infections, fatigue, joint pain, and swelling. However, some people may not experience any noticeable symptoms.

If Your Levels are Low

Low levels of Immunoglobulin G2 (IgG2) could suggest that your immune system isn't functioning as well as it should be. This could be due to a variety of reasons. For instance, you might have an immune deficiency disorder, such as Common Variable Immunodeficiency (CVID) or Selective IgG2 Deficiency, which can cause your body to produce less IgG2. Certain medications, like immunosuppressants used for treating autoimmune diseases or preventing organ transplant rejection, can also lower your IgG2 levels. Additionally, chronic infections or diseases can exhaust your immune system, leading to decreased IgG2. It's also worth noting that some people naturally have lower levels of IgG2, and this doesn't necessarily mean they have a health problem.

Symptoms of Low Levels

Symptoms of low levels of Immunoglobulin G2 might include frequent infections, such as sinus or lung infections, fatigue, and slow recovery from illnesses. However, some people with low IgG2 levels may not experience any noticeable symptoms at all.

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See References

Test for

Immunoglobulin G2

Immunoglobulin G, Subclasses (1-4) by Access Med Labs

Serum

The Immunoglobulin G Subclasses test measures levels of IgG1, IgG2, IgG3, IgG4, and total IgG. It's instrumental in assessing immune function, particularly in patients with recurrent bacterial infections or allergies. This test aids in identifying specific IgG subclass deficiencies that could contribute to immune dysregulation despite normal total IgG levels.

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What is it?

High Levels

Low Levels

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