GI Health
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August 28, 2024

What Causes IBS? Key Factors and Triggers Explained

Written By
Medically Reviewed by
Updated On
September 17, 2024

Living with Irritable Bowel Syndrome (IBS) can be challenging and frustrating. Unpredictable symptoms like abdominal pain, bloating, and changes in bowel habits can make everyday activities feel overwhelming. 

If you have IBS, you know how much it can affect not just your physical health but also your emotional well-being and social life.

Understanding what causes IBS is a vital step toward regaining control and finding relief. Knowing the factors that contribute to your symptoms can help you manage them more effectively and improve your quality of life. 

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What is IBS?

Irritable Bowel Syndrome (IBS) is a common disorder that affects the digestive system, particularly the large intestine. 

People with IBS often experience a range of uncomfortable symptoms including stomach pain, bloating, gas, and changes in bowel habits like diarrhea or constipation. These symptoms can vary from mild to severe and can significantly impact daily life.

IBS  affects about 10-15% of the global population. It is more common in women than in men and often begins before the age of 50.

IBS can affect work, social activities, and overall quality of life. Many people with IBS also experience anxiety and depression.

IBS is categorized into different types based on the predominant bowel habit:

  • IBS-C (Constipation-predominant): This type is characterized by infrequent bowel movements and hard, lumpy stools.
  • IBS-D (Diarrhea-predominant): Individuals with this type experience frequent, loose, or watery stools.
  • IBS-M (Mixed): This type involves alternating periods of constipation and diarrhea.
  • IBS-U (unclassified): The patient meets the criteria for IBS but their symptoms do not predominantly align with the patterns seen in other types.

Common Causes and Triggers of IBS

Here are the most important causes to be aware of:

Genetic Factors

IBS can run in families, suggesting that genetics might play a role. If a close relative like a parent or sibling has IBS, your chances of developing the condition may be higher. 

Certain genetic factors may make individuals more susceptible to IBS.

Gastrointestinal Motility Issues

The intestines use muscle contractions to move food through the digestive tract. In people with IBS, these contractions can be stronger and last longer, causing diarrhea, or they can be weaker, leading to constipation. 

These abnormal movements contribute to the discomfort and irregular bowel habits seen in IBS.  Improper muscle contractions in the intestines can slow down or speed up digestion.

Brain-Gut Interaction

The brain and digestive system are closely linked through a network of nerves. This connection, known as the brain-gut axis, allows the brain to communicate with the digestive system. 

This communication can become disrupted in IBS, leading to heightened sensitivity and digestive issues. 

Stress and anxiety can also have a big impact on IBS. When a person is stressed or anxious, the brain sends signals to the gut that can worsen IBS symptoms. This is why many people notice their symptoms flare up during stressful times.

Food Sensitivities and Intolerances

Certain foods can trigger IBS symptoms. Common culprits include gluten (found in wheat, barley, and rye), dairy products, and FODMAPs, which are certain types of carbohydrates that are hard to digest. 

Identifying and avoiding trigger foods can significantly reduce symptoms. With guidance from a healthcare provider or dietitian, you can create a tailored diet plan to minimize symptom frequency and severity.

Infections and the Gut Microbiome

Some people develop IBS after a severe gastrointestinal infection such as gastroenteritis. This is known as post-infectious IBS.

 An infection can cause lasting changes in the gut. An imbalance in the gut microbiome, the community of bacteria in the intestines, can also contribute to ongoing IBS symptoms. 

Probiotics and dietary changes may help restore balance.

Hormonal Changes

IBS is more common in women, which might be partly due to hormonal differences. Female hormones like estrogen and progesterone can affect how the digestive system works, potentially making women more prone to IBS.

Hormones involved in the menstrual cycle can also influence IBS symptoms. Many women notice that their IBS symptoms worsen during their period due to hormonal fluctuations. This connection suggests that hormones play a role in the condition.

Other Potential Triggers

Certain medications, such as antibiotics, can trigger or worsen IBS symptoms. Antibiotics can disrupt the balance of bacteria in the gut, leading to digestive issues. 

Environmental factors like changes in routine, travel, or even climate, can also trigger IBS symptoms. For example, some people experience flare-ups when traveling due to changes in diet, stress, or disruptions to their regular routine.

Diagnosis of IBS

The Rome IV criteria are widely used to diagnose IBS. 

According to these criteria, a diagnosis can be made if the patient has experienced recurrent abdominal pain on average at least one day per week in the last three months, and this pain is associated with two or more of the following:

  • Pain related to defecation
  • A change in the frequency of stool
  • A change in the form (appearance) of stool

Because IBS shares symptoms with many other digestive disorders, it's crucial to rule out other conditions before making a diagnosis. Conditions such as inflammatory bowel disease (IBD), celiac disease, and gastrointestinal infections can mimic IBS symptoms but require different treatments. 

A thorough evaluation helps ensure that the correct diagnosis is made and that other serious conditions are not overlooked. 

To diagnose IBS and rule out other conditions, doctors may recommend various tests, especially if the symptoms are unclear or severe. Here are some specific tests that might be used:

SIBO Breath Test

This test measures the levels of hydrogen and methane gases in your breath after drinking a special sugar solution. An increase in these gases can indicate Small Intestinal Bacterial Overgrowth (SIBO), a condition that can cause symptoms similar to IBS such as bloating, gas, and diarrhea. 

Examples of this test offered through Rupa Health are: 

Food Sensitivities Test

Identifying specific food sensitivities can help manage IBS symptoms. These tests, often blood tests, can detect reactions to common trigger foods like gluten, dairy, and certain carbohydrates (FODMAPs). Knowing which foods trigger symptoms can guide dietary changes that reduce IBS flare-ups. 

Examples of this test offered through Rupa Health are: 

Comprehensive Stool Test

This test analyzes a sample of your stool to assess the health of your digestive system. It can detect infections, inflammation, the presence of parasites, and imbalances in gut bacteria. This information is valuable for diagnosing IBS and understanding underlying issues contributing to symptoms. 

Examples of this test offered through Rupa Health are: 

Managing and Preventing IBS

Dietary adjustments are often the first step in managing IBS. Many people find that certain foods trigger their symptoms. 

Following a low FODMAP diet can be particularly helpful. This diet involves avoiding specific types of carbohydrates that are hard to digest, such as those found in certain fruits, vegetables, dairy, and grains. 

After a period of elimination, these foods are gradually reintroduced to identify which ones cause issues. Keeping a food diary can also help track what you eat and how it affects your symptoms, making it easier to pinpoint triggers.

Since stress is a common trigger for IBS, stress management is crucial for symptom control. Techniques like mindfulness meditation, deep breathing exercises, and yoga can help reduce stress levels. 

Regular physical activity such as walking or swimming is also beneficial, as it helps lower stress and promotes healthy digestion. 

Some people may benefit from cognitive-behavioral therapy (CBT) which can help change negative thought patterns and reduce anxiety, leading to fewer IBS flare-ups.

In addition to lifestyle changes, various medications can help manage IBS symptoms. Antispasmodics can relieve cramping and pain by relaxing the muscles in the intestines. Laxatives or anti-diarrheal medications are used to manage constipation or diarrhea, respectively. 

Fiber supplements can help regulate bowel movements, especially in cases of IBS with constipation (IBS-C). 

For some, antidepressants may be prescribed in low doses to reduce pain and improve gut-brain communication. 

Probiotics are another option; they can help restore a healthy balance of gut bacteria, which may alleviate symptoms.

Successfully managing IBS often requires a holistic approach that considers the whole person, not just the symptoms. This means combining dietary changes, stress management, and medications with other lifestyle adjustments to improve overall well-being. 

Working with a healthcare team including doctors, dietitians, and therapists can help create a personalized plan that addresses all aspects of IBS. A holistic approach not only helps manage symptoms but also supports mental and emotional health, leading to a better quality of life.

[signup]

Key Takeaways 

Irritable Bowel Syndrome (IBS) is a complex condition characterized by symptoms such as abdominal pain, bloating, and irregular bowel habits. 

Understanding the potential causes and triggers including genetic factors, gastrointestinal motility issues, brain-gut interactions, and food sensitivities is crucial in managing the condition effectively. 

Diagnosis typically involves the use of the Rome IV criteria and ruling out other conditions through various tests.

Effective management of IBS requires a multifaceted approach:

  • Dietary Changes
  • Stress Management
  • Medications and Treatments
  • A Holistic Approach

It’s important to seek medical advice if you suspect you have IBS. A healthcare provider can help you get an accurate diagnosis, rule out other conditions, and develop a treatment plan tailored to your needs.

Ongoing research and increased awareness are essential for improving the lives of those with IBS. As we learn more about this complex condition, better treatments and management strategies will continue to emerge, offering hope for those affected.

Living with Irritable Bowel Syndrome (IBS) can be challenging and frustrating. Unpredictable symptoms like abdominal pain, bloating, and changes in bowel habits can make everyday activities feel overwhelming. 

If you have IBS, you know how much it can affect not just your physical health but also your emotional well-being and social life.

Understanding what may contribute to IBS is a vital step toward managing symptoms and improving quality of life. Knowing the factors that might influence your symptoms can help you manage them more effectively. 

[signup]

What is IBS?

Irritable Bowel Syndrome (IBS) is a common disorder that affects the digestive system, particularly the large intestine. 

People with IBS often experience a range of uncomfortable symptoms including stomach pain, bloating, gas, and changes in bowel habits like diarrhea or constipation. These symptoms can vary from mild to severe and can significantly impact daily life.

IBS  affects about 10-15% of the global population. It is more common in women than in men and often begins before the age of 50.

IBS can affect work, social activities, and overall quality of life. Many people with IBS also experience anxiety and depression.

IBS is categorized into different types based on the predominant bowel habit:

  • IBS-C (Constipation-predominant): This type is characterized by infrequent bowel movements and hard, lumpy stools.
  • IBS-D (Diarrhea-predominant): Individuals with this type experience frequent, loose, or watery stools.
  • IBS-M (Mixed): This type involves alternating periods of constipation and diarrhea.
  • IBS-U (unclassified): The patient meets the criteria for IBS but their symptoms do not predominantly align with the patterns seen in other types.

Common Causes and Triggers of IBS

Here are the most important causes to be aware of:

Genetic Factors

IBS can run in families, suggesting that genetics might play a role. If a close relative like a parent or sibling has IBS, your chances of developing the condition may be higher. 

Certain genetic factors may make individuals more susceptible to IBS.

Gastrointestinal Motility Issues

The intestines use muscle contractions to move food through the digestive tract. In people with IBS, these contractions can be stronger and last longer, causing diarrhea, or they can be weaker, leading to constipation. 

These abnormal movements contribute to the discomfort and irregular bowel habits seen in IBS.  Improper muscle contractions in the intestines can slow down or speed up digestion.

Brain-Gut Interaction

The brain and digestive system are closely linked through a network of nerves. This connection, known as the brain-gut axis, allows the brain to communicate with the digestive system. 

This communication can become disrupted in IBS, leading to heightened sensitivity and digestive issues. 

Stress and anxiety can also have a big impact on IBS. When a person is stressed or anxious, the brain sends signals to the gut that can worsen IBS symptoms. This is why many people notice their symptoms flare up during stressful times.

Food Sensitivities and Intolerances

Certain foods can trigger IBS symptoms. Common culprits include gluten (found in wheat, barley, and rye), dairy products, and FODMAPs, which are certain types of carbohydrates that are hard to digest. 

Identifying and avoiding trigger foods can significantly reduce symptoms. With guidance from a healthcare provider or dietitian, you can create a tailored diet plan to minimize symptom frequency and severity.

Infections and the Gut Microbiome

Some people develop IBS after a severe gastrointestinal infection such as gastroenteritis. This is known as post-infectious IBS.

 An infection can cause lasting changes in the gut. An imbalance in the gut microbiome, the community of bacteria in the intestines, can also contribute to ongoing IBS symptoms. 

Probiotics and dietary changes may help restore balance.

Hormonal Changes

IBS is more common in women, which might be partly due to hormonal differences. Female hormones like estrogen and progesterone can affect how the digestive system works, potentially making women more prone to IBS.

Hormones involved in the menstrual cycle can also influence IBS symptoms. Many women notice that their IBS symptoms worsen during their period due to hormonal fluctuations. This connection suggests that hormones play a role in the condition.

Other Potential Triggers

Certain medications, such as antibiotics, can trigger or worsen IBS symptoms. Antibiotics can disrupt the balance of bacteria in the gut, leading to digestive issues. 

Environmental factors like changes in routine, travel, or even climate, can also trigger IBS symptoms. For example, some people experience flare-ups when traveling due to changes in diet, stress, or disruptions to their regular routine.

Diagnosis of IBS

The Rome IV criteria are widely used to diagnose IBS. 

According to these criteria, a diagnosis can be made if the patient has experienced recurrent abdominal pain on average at least one day per week in the last three months, and this pain is associated with two or more of the following:

  • Pain related to defecation
  • A change in the frequency of stool
  • A change in the form (appearance) of stool

Because IBS shares symptoms with many other digestive disorders, it's crucial to rule out other conditions before making a diagnosis. Conditions such as inflammatory bowel disease (IBD), celiac disease, and gastrointestinal infections can mimic IBS symptoms but require different treatments. 

A thorough evaluation helps ensure that the correct diagnosis is made and that other serious conditions are not overlooked. 

To diagnose IBS and rule out other conditions, doctors may recommend various tests, especially if the symptoms are unclear or severe. Here are some specific tests that might be used:

SIBO Breath Test

This test measures the levels of hydrogen and methane gases in your breath after drinking a special sugar solution. An increase in these gases can indicate Small Intestinal Bacterial Overgrowth (SIBO), a condition that can cause symptoms similar to IBS such as bloating, gas, and diarrhea. 

Examples of this test offered through Rupa Health are: 

Food Sensitivities Test

Identifying specific food sensitivities can help manage IBS symptoms. These tests, often blood tests, can detect reactions to common trigger foods like gluten, dairy, and certain carbohydrates (FODMAPs). Knowing which foods trigger symptoms can guide dietary changes that reduce IBS flare-ups. 

Examples of this test offered through Rupa Health are: 

Comprehensive Stool Test

This test analyzes a sample of your stool to assess the health of your digestive system. It can detect infections, inflammation, the presence of parasites, and imbalances in gut bacteria. This information is valuable for diagnosing IBS and understanding underlying issues contributing to symptoms. 

Examples of this test offered through Rupa Health are: 

Managing and Supporting IBS

Dietary adjustments are often the first step in managing IBS. Many people find that certain foods trigger their symptoms. 

Following a low FODMAP diet can be particularly helpful. This diet involves avoiding specific types of carbohydrates that are hard to digest, such as those found in certain fruits, vegetables, dairy, and grains. 

After a period of elimination, these foods are gradually reintroduced to identify which ones cause issues. Keeping a food diary can also help track what you eat and how it affects your symptoms, making it easier to pinpoint triggers.

Since stress is a common trigger for IBS, stress management is crucial for symptom control. Techniques like mindfulness meditation, deep breathing exercises, and yoga can help reduce stress levels. 

Regular physical activity such as walking or swimming is also beneficial, as it helps lower stress and promotes healthy digestion. 

Some people may benefit from cognitive-behavioral therapy (CBT) which can help change negative thought patterns and reduce anxiety, leading to fewer IBS flare-ups.

In addition to lifestyle changes, various medications can help manage IBS symptoms. Antispasmodics can relieve cramping and pain by relaxing the muscles in the intestines. Laxatives or anti-diarrheal medications are used to manage constipation or diarrhea, respectively. 

Fiber supplements can help regulate bowel movements, especially in cases of IBS with constipation (IBS-C). 

For some, antidepressants may be prescribed in low doses to reduce pain and improve gut-brain communication. 

Probiotics are another option; they can help support a healthy balance of gut bacteria, which may alleviate symptoms.

Successfully managing IBS often requires a holistic approach that considers the whole person, not just the symptoms. This means combining dietary changes, stress management, and medications with other lifestyle adjustments to improve overall well-being. 

Working with a healthcare team including doctors, dietitians, and therapists can help create a personalized plan that addresses all aspects of IBS. A holistic approach not only helps manage symptoms but also supports mental and emotional health, leading to a better quality of life.

[signup]

Key Takeaways 

Irritable Bowel Syndrome (IBS) is a complex condition characterized by symptoms such as abdominal pain, bloating, and irregular bowel habits. 

Understanding the potential causes and triggers including genetic factors, gastrointestinal motility issues, brain-gut interactions, and food sensitivities is crucial in managing the condition effectively. 

Diagnosis typically involves the use of the Rome IV criteria and ruling out other conditions through various tests.

Effective management of IBS requires a multifaceted approach:

  • Dietary Changes
  • Stress Management
  • Medications and Treatments
  • A Holistic Approach

It’s important to seek medical advice if you suspect you have IBS. A healthcare provider can help you get an accurate diagnosis, rule out other conditions, and develop a treatment plan tailored to your needs.

Ongoing research and increased awareness are essential for improving the lives of those with IBS. As we learn more about this complex condition, better treatments and management strategies will continue to emerge, offering hope for those affected.

The information provided is not intended to be a substitute for professional medical advice. Always consult with your doctor or other qualified healthcare provider before taking any dietary supplement or making any changes to your diet or exercise routine.

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National Heart Lung and Blood Institute
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National Institutes of Health
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Clinical Infectious Diseases
Peer Reviewed Journal
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Brain
Peer Reviewed Journal
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The Journal of Rheumatology
Peer Reviewed Journal
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Journal of the National Cancer Institute (JNCI)
Peer Reviewed Journal
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Journal of Cardiovascular Magnetic Resonance
Peer Reviewed Journal
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Hepatology
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The American Journal of Clinical Nutrition
Peer Reviewed Journal
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The Journal of Bone and Joint Surgery
Peer Reviewed Journal
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Kidney International
Peer Reviewed Journal
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The Journal of Allergy and Clinical Immunology
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Annals of Surgery
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Chest
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The Journal of Neurology, Neurosurgery & Psychiatry
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Blood
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Gastroenterology
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The American Journal of Respiratory and Critical Care Medicine
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The American Journal of Psychiatry
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Diabetes Care
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The Journal of the American College of Cardiology (JACC)
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The Journal of Clinical Oncology (JCO)
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Journal of Clinical Investigation (JCI)
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Circulation
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JAMA Internal Medicine
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PLOS Medicine
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Annals of Internal Medicine
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Nature Medicine
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The BMJ (British Medical Journal)
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The Lancet
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Journal of the American Medical Association (JAMA)
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Pubmed
Comprehensive biomedical database
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Harvard
Educational/Medical Institution
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Cleveland Clinic
Educational/Medical Institution
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Mayo Clinic
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The New England Journal of Medicine (NEJM)
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Johns Hopkins
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