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October 6, 2023

Using the Total Mycotoxin Panel in Clinic

Medically Reviewed by
Updated On
September 17, 2024

Mycotoxins can invade our homes, workplaces, outdoor environments, and our bodies. Mycotoxins are toxic elements that are produced by various fungi or molds. Your patients may be exposed to these biological toxins, which can create adverse health effects that impact their energy levels, cognitive function, and overall health. Symptoms may vary for your patients and mimic other conditions; thus, mycotoxin diagnosis often gets overlooked and can go undiagnosed. 

Luckily, there is a reliable mycotoxin screen that can be ordered for these patients who are suspected of mycotoxin-related illness. The Total Mycotoxins Panel by RealTime Laboratories can provide insights into the levels of mycotoxin exposure, enabling tailored treatment strategies to reduce exposure levels and improve overall health outcomes.

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What is the Total Mycotoxin Panel by RealTime Laboratories?

The Total Mycotoxin Panel by RealTime Laboratories can asses for 16 different mycotoxins that can wreak havoc on your patient's health. This lab's doctors and scientists have thoroughly researched these mycotoxins to determine the most clinically significant mycotoxin markers to assess. Your patients can complete this mycotoxin panel simply through a urine sample as the least invasive and most stable option. 

This test detects the top common mycotoxin groups that can impact health, including Aflatoxins, Ochratoxins, Macrocyclic, and Trichothecenes. The testing method used is ELISA, which is highly sensitive to mycotoxin antibodies. Detection levels of these mycotoxins are displayed for clinical use as parts-per-billion (ppb) as standardized by the FDA, WHO, CDC, and Food industry. The results of this test will uncover the presence of each mycotoxin tested and their present levels.

Which Patients Are the Total Mycotoxin Panel Best Used For?

Mycotoxin exposure can lead to a wide variety of harmful health effects. When considering this test for your patients, you will want to look at their possible chronic exposure, as these toxins can be present in their homes or work. You may need to take a thorough intake on patients you suspect have mycotoxin-related symptoms, such as unexplained immune issues, chronic fatigue, consistent sinus problems, neuropathy, worsening asthma, cognitive issues, increased chemical sensitivities, or depression. The intake should evaluate their physical surrounding environments and may include a history of water damage or leaks in the building they are most often in. 

They should also be asked if they've smelled mold in their environments, as this smell can usually indicate mold issues. Having a family history of allergies can increase their susceptibility to mold reactions and should be assessed as well. Conditions that stem from mold toxicity also include lung disease, neurotoxicity, decreased kidney or lung function, immune suppression, mood imbalances, anemia, congenital disabilities, digestive issues, skin disruptions, and even cancer.

What Does the Total Mycotoxin Panel Measure?

The Total Mycotoxin Panel measures 16 of the most common mycotoxins known to be toxigenic and impact human health, including the mycotoxin groups, Aflatoxins, Ochratoxins, Macrocyclic Trichothecenesand, and Gliotoxins. It will also assess for black mold caused by Stachybotrys. 

This test will assess for Aflatoxins that can be consumed through food or contacted in environments that have been known to be carcinogenic or create liver, kidney, and gut problems. Ochratoxins are also measured because they are considered toxic to the kidneys. Toxins from Macrocyclic Trichothecenes can come from grains, buildings, and HVAC, causing digestive, metabolic, skin, cardiovascular, immune, metabolic, reproductive, and nervous system issues. Glitoxins are produced from some of the most common fungi, such as Aspergillus, Candida, and Penicillium, and can cause immunosuppression and DNA damage. If you suspect that your patient has been chronically exposed to mold, this test should be utilized to detect the levels of these mycotoxins.

How to Use the Total Mycotoxin Panel by RealTime Laboratories in Clinic

Here are the instructions for the Total Mycotoxin Panel for your patients: 

Preparation Before Sample Collection:

  • Avoid collecting samples during your period.
  • No other preparation is needed for the collection.

Urine Sample Collection:

  • The best time to collect is first-morning urine.
  • Use the provided conical cup.
  • Transfer the urine into a specimen tube and only fill the tube halfway.
  • Place the cap on the tube and safely secure it.
  • Make sure to put your name, date of birth, and collection date and time on the collection tube.
  • Complete the provided lab requisition form.

Handling and Sending Samples:

  • Put the sample in a biohazard bag.
  • Place the bag in the provided test kit box.
  • Place the test kit box with the sample in the freezer until it can be shipped.
  • You must ship the sample within 48 hours.
  • Send samples using the prepaid mailer and keep the tracking number.

Results and Follow-Up:

Results generally take 7-14 days after the lab gets the samples, but they are not guaranteed.

The provider will provide notification of the results and schedule a follow-up time.

Additional tests may be necessary to identify further factors related to symptoms.

Labs to Consider for Further Refinement of Treatments

Here are some other functional labs from RealTime Laboratories to consider:

Total Mycotoxin Panel Follow-Up

Customized detox and avoidance plans may be required based on the patient's lab results. These plans can involve educating patients on reducing toxin exposure through lifestyle changes, providing tailored nutrition guidance for enhanced toxin elimination, and suggesting specific supplements. It's advisable to schedule a retest in 3-6 months to track progress and fine-tune treatment strategies as needed.

EMMA

EMMA stands for Environmental Mold and Mycotoxin Assessment. The EMMA test assesses for molds and mycotoxins in the patient's environment. It analyzes the 16 mycotoxins of the total mycotoxin panel and adds an additional evaluation of the 12 most toxigenic molds. Instead of doing a spore count as what was done with the Total Mycotoxin Panel, they will be utilizing a fungal count Dx test that shows fungal elements. This testing function allows for greater sensitivity so molds that were once undetectable can be detected. Samples of the patient's HVAC filter or a swab of an area with suspected mold is sent in for testing. This test can be combined with the Total Mycotoxin Panel to determine the exact exposure location so it can be properly removed.

Candida Panel

Candida is considered an invasive fungal infection. This fungus can cause gastrointestinal, skin, urogenital, or systemic issues. There are five candida species that cause over 90% of issues in humans. The Candida Panel can detect these top five candida species that can negatively impact health. This test utilizes PCR technology for sensitivity to identify these five candida species within patients. If your patient is suspected of being susceptible or sensitive to fungus or mold, this test should also be considered in conjunction with the Total Mycotoxin Panel.

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Summary

If your patient is spending time in environments that are at risk for mold, such as damp or water-damaged buildings, or they have unexplained immune or fatigue issues, a mycotoxin screening may be indicated for them. Mycotoxin exposure and diagnosis are often overlooked and should be explored for relevant patients, as this exposure can lead to chronic health issues, including cancer. The Total Mycotoxin Panel can assist in detecting the common mycotoxins that are responsible for mycotoxin-related issues. Clinical and environmental history will be crucial in determining the specific routes of treatment actions to take for these patients. Keep in mind that additional tests may be needed, such as the EMMA test, to find the culprit of the mycotoxin exposure. Once all of these elements are examined for your patient, comprehensive treatment can be implored to remove the exposure, eliminate the toxins from their body, and restore their health.

Learn More About The Total Mycotoxin Panel From RealTime Laboratories

Mycotoxins can be found in various environments, including homes and workplaces. Mycotoxins are substances produced by certain fungi or molds. People may be exposed to these substances, which could potentially affect their energy levels, cognitive function, and overall well-being. Symptoms can vary and may resemble other conditions, making mycotoxin exposure challenging to identify.

There is a mycotoxin screening available for individuals suspected of having mycotoxin-related health concerns. The Total Mycotoxins Panel by RealTime Laboratories can provide insights into mycotoxin exposure levels, which may help in developing strategies to manage exposure and support overall health.

[signup]

What is the Total Mycotoxin Panel by RealTime Laboratories?

The Total Mycotoxin Panel by RealTime Laboratories assesses for 16 different mycotoxins that may impact health. This lab's doctors and scientists have researched these mycotoxins to identify significant markers for assessment. The panel is completed through a urine sample, which is a non-invasive and stable method.

This test detects common mycotoxin groups that may affect health, including Aflatoxins, Ochratoxins, Macrocyclic, and Trichothecenes. The testing method used is ELISA, which is sensitive to mycotoxin antibodies. Detection levels are displayed as parts-per-billion (ppb), following standards by the FDA, WHO, CDC, and the food industry. The results indicate the presence and levels of each mycotoxin tested.

Which Patients Are the Total Mycotoxin Panel Best Used For?

Mycotoxin exposure may be associated with various health effects. When considering this test, it's important to evaluate potential chronic exposure, as these substances can be present in living or working environments. A thorough intake may be needed for individuals with symptoms that could be related to mycotoxin exposure, such as unexplained immune issues, fatigue, sinus problems, neuropathy, asthma, cognitive issues, chemical sensitivities, or mood changes. The intake should consider environmental factors, including any history of water damage or mold presence.

Individuals should also be asked about any mold odors in their environments, as this can indicate mold issues. A family history of allergies may increase susceptibility to mold reactions and should be considered. Conditions potentially related to mold exposure include lung issues, neurotoxicity, changes in kidney or lung function, immune suppression, mood imbalances, anemia, digestive issues, skin disruptions, and other health concerns.

What Does the Total Mycotoxin Panel Measure?

The Total Mycotoxin Panel measures 16 common mycotoxins that may impact health, including Aflatoxins, Ochratoxins, Macrocyclic Trichothecenes, and Gliotoxins. It also assesses for black mold caused by Stachybotrys.

This test evaluates Aflatoxins, which can be found in food or environments and are known to affect liver, kidney, and gut health. Ochratoxins are measured due to their potential impact on kidney health. Macrocyclic Trichothecenes can be present in grains, buildings, and HVAC systems, potentially affecting various body systems. Gliotoxins, produced by fungi like Aspergillus, Candida, and Penicillium, may influence immune function. If chronic mold exposure is suspected, this test can help detect mycotoxin levels.

How to Use the Total Mycotoxin Panel by RealTime Laboratories in Clinic

Here are the instructions for the Total Mycotoxin Panel:

Preparation Before Sample Collection:

  • Avoid collecting samples during menstruation.
  • No other preparation is needed for the collection.

Urine Sample Collection:

  • Collect first-morning urine.
  • Use the provided conical cup.
  • Transfer urine into a specimen tube, filling it halfway.
  • Secure the cap on the tube.
  • Label the tube with your name, date of birth, and collection date and time.
  • Complete the lab requisition form.

Handling and Sending Samples:

  • Place the sample in a biohazard bag.
  • Put the bag in the test kit box.
  • Freeze the test kit box until shipping.
  • Ship the sample within 48 hours.
  • Use the prepaid mailer and keep the tracking number.

Results and Follow-Up:

Results typically take 7-14 days after the lab receives the samples, but this timeframe is not guaranteed.

The provider will notify you of the results and schedule a follow-up.

Additional tests may be needed to explore other factors related to symptoms.

Labs to Consider for Further Refinement of Treatments

Here are some other functional labs from RealTime Laboratories to consider:

Total Mycotoxin Panel Follow-Up

Customized plans may be needed based on lab results. These plans can include guidance on reducing exposure through lifestyle changes, nutrition advice, and supplement suggestions. A retest in 3-6 months may be helpful to monitor progress and adjust strategies.

EMMA

EMMA stands for Environmental Mold and Mycotoxin Assessment. The EMMA test evaluates molds and mycotoxins in the environment. It analyzes the 16 mycotoxins of the Total Mycotoxin Panel and includes an assessment of 12 additional molds. This test uses a fungal count Dx test for greater sensitivity. Samples from HVAC filters or suspected mold areas are tested. This test can be combined with the Total Mycotoxin Panel to identify exposure sources.

Candida Panel

Candida is a type of fungus that can affect various body systems. This fungus may cause gastrointestinal, skin, urogenital, or systemic issues. The Candida Panel detects five Candida species that may impact health. It uses PCR technology for sensitivity. If fungal or mold sensitivity is suspected, this test can be considered alongside the Total Mycotoxin Panel.

[signup]

Summary

If someone spends time in environments at risk for mold, such as damp or water-damaged buildings, or has unexplained immune or fatigue issues, a mycotoxin screening may be worth considering. Mycotoxin exposure is often overlooked and should be explored for relevant individuals, as it may contribute to chronic health issues. The Total Mycotoxin Panel can help detect common mycotoxins associated with these concerns. Clinical and environmental history is important in determining appropriate actions. Additional tests, like the EMMA test, may be needed to identify exposure sources. Once these elements are assessed, comprehensive strategies can be developed to manage exposure and support health.

Learn More About The Total Mycotoxin Panel From RealTime Laboratories

The information provided is not intended to be a substitute for professional medical advice. Always consult with your doctor or other qualified healthcare provider before taking any dietary supplement or making any changes to your diet or exercise routine.

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Lab Tests in This Article

(2021, September 27). Retrieved September 18, 2023, from Rupa Health website: https://www.rupahealth.com/post/mycotoxins-101

Brewer, J. H., Thrasher, J. D., Straus, D. C., Madison, R. A., & Hooper, D. (2013). Detection of mycotoxins in patients with chronic fatigue syndrome. Toxins, 5(4), 605–617. https://doi.org/10.3390/toxins5040605

Basic Facts about Mold and Dampness . (2023). Retrieved September 18, 2023, from https://www.cdc.gov/mold/faqs.htm

‌Fatigue, Body Aches, and Rashes Are Symptoms of Exposure to This Dangerous Toxin. (2022, October 12). Retrieved September 18, 2023, from Rupa Health website: https://www.rupahealth.com/post/fatigue-body-aches-and-rashes-are-symptoms-of-exposure-to-this-dangerous-toxin

‌Buy (EMMA) Environmental Mold and Mycotoxin Test. (2023, April 17). Retrieved September 18, 2023, from RealTime Laboratories website: https://realtimelab.com/product/environmental-mold-and-mycotoxin-assessment/

Candida and Invasive Fungal Infections | RealTime Laboratories. (2022, October 19). Retrieved September 18, 2023, from RealTime Laboratories website: https://realtimelab.com/candida-and-invasive-fungal-infections/

Weinberg, J. ‌(2023, June 6). Retrieved September 18, 2023, from Rupa Health website: https://www.rupahealth.com/post/a-functional-medicine-candida-overgrowth-protocol

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