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Topical Treatments for Psoriasis: Creams, Ointments, and More

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Medically Reviewed by
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Ayesha Bryant
MSPH, MD

Living with psoriasis can be challenging, especially when the discomfort and visible effects impact your daily life. If you're managing this condition, finding the right treatment is crucial to feeling better and gaining more control over your skin. Topical treatments, such as creams, ointments, and lotions, are often the first line of defense in soothing the symptoms of psoriasis. 

These treatments are applied directly to the skin, offering targeted relief and helping to reduce redness, itching, and scaling. This article explores the various treatment options for psoriasis.    

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Understanding Psoriasis and Its Treatment Needs

Psoriasis is a chronic skin condition that affects millions of people worldwide. It is characterized by red, scaly patches of skin that can appear anywhere on the body, though they are most commonly found on the elbows, knees, scalp, and lower back. 

These patches, known as plaques, are caused by an overactive immune system that speeds up the production of skin cells, leading to the buildup of these cells on the skin's surface. Psoriasis can vary in severity, from small, localized patches to widespread areas covering large parts of the body. 

There are several types of psoriasis, including plaque psoriasis (the most common type), guttate psoriasis, inverse psoriasis, pustular psoriasis, and erythrodermic psoriasis. Each type has its unique characteristics and may require different treatment approaches. For many individuals with mild to moderate psoriasis, topical treatments are often the first choice for managing symptoms. 

These treatments are applied directly to the skin, where they can target the specific areas affected by the condition. Topical therapies are generally preferred because they are less likely to cause systemic side effects than oral or injectable medications. 

They can effectively reduce inflammation, slow the rapid turnover of skin cells, and relieve the discomfort associated with psoriasis, such as itching and pain. The primary goals of topical therapy for psoriasis are to reduce inflammation, slow down the rapid turnover of skin cells, and relieve itching and discomfort.

Types of Topical Treatments for Psoriasis

Here are some of the most commonly used topical treatments for psoriasis and how they work to bring relief:

1. Corticosteroids

How They Work:

Corticosteroids are anti-inflammatory agents that help reduce redness, swelling, and irritation in the affected areas. They work by suppressing the immune system's activity in the skin, thereby decreasing the inflammation that causes psoriasis symptoms.

Forms Available:

Corticosteroids are available in various strengths and formulations, including creams, ointments, lotions, gels, and foams. The choice of formulation often depends on the specific area of the body being treated and the severity of the symptoms. 

  • Creams are lighter, water-based, and quickly absorbed, making them suitable for moist or weeping areas but may require more frequent application as they can be rubbed off easily. 
  • Ointments are oil-based, providing a thicker, occlusive layer that locks in moisture and delivers medication more deeply, making them ideal for dry, thick plaques and longer-lasting, though their greasy texture can be less desirable for areas prone to friction. 
  • Lotions are lighter and spread easily, great for larger or hairy areas like the scalp but may be less effective for thick plaques. 
  • Gels dry quickly and are non-greasy, suitable for hairy areas, but the alcohol base can be drying or irritating. 
  • Foams combine the benefits of quick absorption and convenience, often preferred for large areas or those with hair, offering a balance between efficacy and ease of use without the greasy feel of ointments.

When to Use:

Corticosteroids are commonly used during psoriasis flare-ups and are particularly effective for treating sensitive areas like the face, groin, or armpits. They should be used under the guidance of a healthcare provider to ensure safe and effective use.

Potential Side Effects:

Prolonged use of corticosteroids can lead to side effects such as thinning of the skin, stretch marks, and increased risk of infections. It is important to follow medical advice carefully to minimize these risks.

2. Vitamin D Analoges

How They Work:

Vitamin D analogs help slow down the rapid production of skin cells, a hallmark of psoriasis. They also help to flatten and reduce the size of plaques.

Examples:

Common examples include calcipotriene and calcitriol.

Combining with Other Treatments:

Vitamin D analogs are often used in combination with corticosteroids to enhance the effectiveness of treatment and reduce the potential side effects of corticosteroids.

Potential Side Effects:

While generally well-tolerated, vitamin D analogs can sometimes cause skin irritation or a burning sensation at the application site.

3. Topical Retinoids

How They Work:

Topical retinoids are derivatives of vitamin A that help normalize skin cell production, thereby reducing the buildup of plaques.

Examples:

Tazarotene is a common topical retinoid used in the treatment of psoriasis.

When to Use:

Topical retinoids are best suited for treating thick plaques and are often used on areas of the body like the arms and legs.

Potential Side Effects:

These treatments can cause skin irritation and increase sensitivity to sunlight, so it is important to use sunscreen and follow application instructions carefully.

4. Calcineurin Inhibitors

How They Work:

Calcineurin inhibitors work by suppressing the immune system's activity, thereby reducing inflammation in the skin.

Examples:

Tacrolimus and pimecrolimus are common calcineurin inhibitors used in topical psoriasis treatment.

When to Use:

These are particularly useful for treating sensitive areas such as the face, neck, and skin folds where other treatments might be too harsh.

Potential Side Effects:

Some individuals may experience burning or itching at the application site, but these side effects usually diminish with continued use.

5. Coal Tar

How It Works:

Coal tar has been used for decades to treat psoriasis. It helps slow skin cell growth, reduce scaling, and alleviate itching.

Forms Available:

Coal tar is available in creams, ointments, and shampoos, making it a versatile option for different types of psoriasis, including scalp psoriasis.

Considerations:

While effective, coal tar has a strong odor and can stain clothing and bedding. It can also make the skin more sensitive to sunlight.

6. Salicylic Acid

How It Works:

Salicylic acid softens and removes scales from the skin, making it easier for other topical treatments to penetrate and work more effectively.

Combining with Other Treatments:

Salicylic acid is often used in conjunction with other topical therapies to enhance their effectiveness.

Potential Side Effects:

Overuse of salicylic acid can lead to skin irritation and dryness, so it’s important to use it as directed.

7. Moisturizers and Emollients

Role in Psoriasis Care:

Moisturizers and emollients are key in managing psoriasis. They keep the skin hydrated and reduce dryness and scaling. They also help support the skin barrier and make other treatments more effective.

Types Available:

These products come in various forms, including creams, ointments, and lotions, and can be used throughout the day to keep the skin moisturized.

When to Use:

Daily moisturizers and emollients are recommended to maintain skin health and complement other psoriasis treatments.

Choosing the Right Topical Treatment

The right choice depends on several factors, including the severity of your psoriasis, the location of the plaques, your personal preferences, and potential side effects of the treatments. Below, we’ll explore these considerations and offer guidance on how to make the best decisions for your treatment plan.

Factors to Consider

When choosing a topical treatment, it's essential to take into account:

  • Severity of Psoriasis: Mild cases may only require a simple moisturizer, while more severe cases might need stronger treatments like corticosteroids or combination therapies.
  • Location of Plaques: Some areas of the body, such as the face or skin folds, may be more sensitive and require milder treatments, such as calcineurin inhibitors.
  • Patient Preference: Your comfort and preference play a significant role in choosing a treatment. For example, you might prefer a cream over an ointment based on how it feels on your skin.
  • Potential Side Effects: Understanding the possible side effects, such as skin thinning from corticosteroids, helps make an informed decision and balance benefits versus risks.

In some cases, combining different topical treatments can provide better results than a single treatment alone. For example, pairing a corticosteroid with a vitamin D analog can enhance its effectiveness while potentially reducing side effects. This approach, known as combination therapy, allows for a more tailored treatment plan that simultaneously addresses multiple aspects of psoriasis management.

Psoriasis is a unique condition that affects each person differently, so it's important to work closely with your healthcare provider. They can help personalize your treatment plan, ensuring it’s tailored to your specific symptoms, skin type, and lifestyle. Regular check-ins with your healthcare provider allow for adjustments to your treatment plan as needed, ensuring it remains effective over time.

Application Tips and Best Practices

Proper application of topical treatments is essential for their effectiveness. Here’s a step-by-step guide to help you apply them correctly:

  1. Wash your hands and the area of skin where the treatment will be applied. Pat dry gently with a towel.
  2. Take a small amount of the treatment and gently apply a thin layer to the affected area. Avoid rubbing it in too vigorously.
  3. Pay close attention to the instructions provided with your treatment, as some may require specific application methods or timing.
  4. After applying the treatment, wash your hands to prevent the medication from spreading to other parts of your body.

Dos and Don’ts

To maximize the effectiveness of your treatment and minimize potential side effects, keep these tips in mind:

  • Do: Follow your healthcare provider’s instructions carefully.
  • Do: Use the recommended amount; more is not always better.
  • Don’t: Apply treatments too thickly, as this can increase the risk of side effects without improving results.
  • Don’t: Cover treated areas with tight bandages or clothing unless instructed to do so, as this can lead to irritation or increased absorption of the medication.

Consistency is key to seeing positive results from topical treatments. Establishing a regular treatment routine helps ensure that you’re applying the medication as prescribed and maintaining its effectiveness over time. Setting reminders or incorporating your treatment into your daily skincare routine can help you stay on track.

Managing Side Effects

While topical treatments are generally well-tolerated, some people may experience side effects such as skin irritation, dryness, or burning. Here are a few strategies to manage these:

  • Use moisturizers to keep the skin hydrated and minimize dryness.
  • Avoid potential irritants, such as harsh soaps or hot water, which can exacerbate side effects.
  • Consult a healthcare provider if side effects persist or worsen, as adjustments to the treatment plan may be necessary.

Special Considerations for Sensitive Areas

Psoriasis can affect various parts of the body, each with unique treatment challenges. Sensitive areas, such as the scalp, face, skin folds, hands, and feet, require special care and attention to ensure effective treatment while minimizing irritation and discomfort.

Treating the Scalp

The scalp can be one of the most challenging areas to treat due to the presence of hair, which can make applying and absorbing topical treatments more difficult. Here are some best practices for managing scalp psoriasis:

  • Use Special Formulations: Shampoos, foams, and solutions are often designed specifically for scalp psoriasis. These products are easier to apply and are formulated to penetrate the hair and reach the scalp.
  • Apply Properly: Part your hair in sections to ensure the treatment reaches the affected areas. Massage the product gently into the scalp.
  • Timing is Key: To allow the treatment to work effectively, leave it on for the recommended amount of time. Some treatments must be washed out after a certain period, while others can be left on.
  • Gentle Cleansing: Use a gentle shampoo that won’t irritate the scalp, especially if you are using medicated treatments that may already be drying.

Facial and Skin Fold Psoriasis

The skin on the face and in skin folds (such as under the breasts, in the groin area, or under the arms) is more delicate and prone to irritation. When treating psoriasis in these areas, it’s important to use milder treatments:

  • Opt for Mild Treatments: Calcineurin inhibitors, such as tacrolimus or pimecrolimus, are often recommended for these sensitive areas because they reduce inflammation without the risk of thinning the skin.
  • Avoid Harsh Ingredients: Avoid treatments that contain alcohol or other drying agents, as they can cause additional irritation.
  • Apply Sparingly: Use only a small amount of treatment and apply it gently to avoid over-irritating these sensitive areas.
  • Consider Moisturizers: Keeping these areas well-moisturized can help reduce friction and irritation, making treatments more comfortable.

Hands and Feet

Psoriasis on the hands and feet can be particularly stubborn due to the thicker skin in these areas. Here are some tips for managing it effectively:

  • Use Stronger Treatments: Thicker skin may require more potent treatments, such as stronger corticosteroids or retinoids, to penetrate effectively.
  • Moisturize Regularly: Keeping the skin hydrated is crucial, especially on the hands and feet, where psoriasis can cause cracking and pain.
  • Wear Protective Gloves or Socks: After applying treatments, consider wearing cotton gloves or socks to help the medication absorb and protect the skin.
  • Be Mindful of Irritants: Avoid exposure to harsh soaps, detergents, or chemicals that can further aggravate the skin on your hands and feet.

Monitoring Progress and When to Seek Help

Keeping a record of symptoms and treatment responses can help identify patterns and triggers, allowing for better management of psoriasis. Document the areas treated, the treatments used, and any changes in your symptoms. Note improvements, as well as any flare-ups or side effects. Taking photos can be a helpful way to monitor changes in your skin over time. This can also be useful when discussing your progress with your healthcare provider.

If symptoms persist or side effects become bothersome, it may be time to adjust the treatment plan. Regular consultations with a dermatologist are essential to optimize treatment strategies.

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Key Takeaways

  • Topical treatments for psoriasis, such as corticosteroids, vitamin D analogues, and moisturizers, are often the first line of defense. They offer targeted relief by reducing inflammation, slowing skin cell turnover, and soothing discomfort.
  • The choice of topical treatment depends on factors like the severity of psoriasis, the location of plaques, patient preferences, and potential side effects. Combination therapies sometimes provide better results.
  • Proper application techniques, consistency in use, and careful monitoring of side effects are crucial to maximizing the effectiveness of these treatments and minimizing risks.
The information provided is not intended to be a substitute for professional medical advice. Always consult with your doctor or other qualified healthcare provider before taking any dietary supplement or making any changes to your diet or exercise routine.
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