Lab Education
|
November 1, 2024

Top 7 Functional Medicine Labs Ordered By Allergists

Medically Reviewed by
Updated On
December 11, 2024

The rise of functional medicine is transforming the way allergists diagnose and treat allergies. By focusing on the root causes, such as gut health, food sensitivities, and environmental triggers, functional medicine offers a more comprehensive approach to managing allergies. For allergists, integrating functional medicine labs into their practice enhances their ability to deliver personalized, effective care. 

This article explores the most commonly ordered functional medicine labs for allergists, emphasizing their role in improving diagnostic accuracy and providing tailored treatment plans. Choosing the right tests is key to achieving long-term relief for chronic allergy sufferers.

Sign Up to Order Labs

[signup]

The Role of Functional Medicine in Allergy Treatment

Functional medicine is a patient-centered approach that focuses on identifying and addressing the root causes of health issues rather than just treating symptoms. 

In the field of allergies, functional medicine looks beyond surface problems, like sneezing or rashes, to explore deeper issues like inflammation, immune system imbalances, and gut health. Allergists are beginning to incorporate functional medicine because it offers a holistic approach to improving long-term health outcomes.

Common Conditions Addressed by Functional Medicine in Allergies

Functional medicine is beneficial for addressing conditions like asthma, eczema, hay fever, and food intolerances. Allergists using this method often focus on improving gut health since many allergies and immune system issues are linked to the digestive system. 

For instance, an allergist may recommend dietary changes, supplements, or stress management techniques alongside traditional treatments to manage asthma or eczema. This integrated approach can lead to better health and fewer allergic flare-ups.

Functional Medicine Labs Most Commonly Ordered by Allergists

Allergists may suggest the following labs:

Comprehensive Gut Microbiome Testing

Gut health is a crucial factor in managing allergies, and comprehensive gut microbiome testing is often used in functional medicine to understand the digestive system's role in allergic responses. 

Many functional medicine practitioners believe that a healthy gut is the foundation for a well-functioning immune system, and disruptions in gut health can lead to or worsen allergic conditions.

Popular labs: 

  • The GI-MAP test provides detailed insights into the digestive system's balance of good and bad bacteria, parasites, and yeast. This test also measures markers of gut inflammation and immune response, key factors in allergy management. 
  • Doctor’s Data Comprehensive Stool Analysis also provides similar information, allowing allergists to identify potential gut microbiome imbalances that could trigger or exacerbate allergic reactions.

Food Sensitivity and Intolerance Testing

Food sensitivities and intolerances are often overlooked causes of allergies. Identifying and addressing these food-related triggers can help manage and reduce allergic symptoms such as hives and eczema. 

Unlike traditional food allergy testing, which looks for immediate allergic responses, food sensitivity and intolerance testing examines delayed reactions that may not appear for hours or days after eating certain foods.

Popular labs:  

  • MRT tests for over 170 foods and chemicals to determine how a person’s immune system reacts. It measures the release of mediators, chemicals that white blood cells release during an allergic response. 
  • IgG Food Panel evaluates the body's immune response to specific foods by measuring IgG antibodies. Identifying problem foods allows allergists to create a tailored elimination diet to reduce inflammation and allergic symptoms.

Environmental Allergen Testing

Environmental allergens such as mold, pollen, and pet dander can significantly contribute to allergy flare-ups, and testing for these allergens is an essential step in identifying what may be causing chronic symptoms like sneezing, wheezing, and skin irritation. 

Functional medicine often takes a broader approach by looking at immediate allergens and hidden or chronic exposures that can contribute to a weakened immune system.

Popular labs:    

  • ELISA/ACT Biotechnologies offers comprehensive tests for environmental allergens, including pollen, dust mites, mold, and animal dander. 
  • MycoTox Profile focuses specifically on mold exposure and identifies various mycotoxins in the body that could contribute to allergic symptoms.

IgE and IgG Antibody Testing

IgE and IgG antibodies play different roles in allergic reactions, and understanding the differences between these immune responses can guide effective allergy treatment. 

  • IgE antibodies are responsible for immediate allergic reactions, such as those experienced with hay fever or food allergies. In contrast, IgG antibodies can contribute to delayed reactions, leading to chronic symptoms that are harder to trace.
  • High IgE levels are often associated with classic allergic reactions like hay fever or asthma. In contrast, elevated IgG levels suggest delayed food sensitivities that can cause chronic symptoms like eczema or digestive issues.

Popular labs:  

  • Detailed panels of immune system reactions to various foods and environmental triggers, giving insight into immediate and delayed allergic responses.
  • IgE and IgG testing allow allergists to identify specific triggers and tailor treatments accordingly. 

Organic Acid Testing (OAT)

Organic Acid Testing (OAT) is used to assess metabolic function and identify nutritional deficiencies, which can be linked to allergic conditions. 

This test measures organic acids in urine, which are byproducts of metabolism. Imbalances in these markers can indicate issues such as yeast overgrowth, bacterial infections, or nutrient deficiencies, all of which may contribute to allergic reactions.

Popular labs:  

  • The Mosaic OAT test is comprehensive, evaluating over 70 different metabolic markers to provide a detailed view of a patient’s biochemical health. 
  • Organix test helps identify nutritional deficiencies, neurotransmitter imbalances, and gut dysbiosis, which can affect the immune system and trigger allergic reactions.

Heavy Metal Toxicity Testing

Heavy metal exposure has been linked to various health issues, including allergic reactions. Toxic metals such as lead, mercury, and arsenic can weaken the immune system, making the body more prone to allergic responses. 

Functional medicine practitioners often use heavy metal toxicity testing to identify whether these harmful substances are contributing to a patient’s allergy symptoms.

Popular labs:  

  • Doctor’s Data and Quicksilver Scientific offer heavy metal toxicity tests through Rupa Health. These tests typically use urine or blood samples to measure the levels of toxic metals in the body. Once identified, allergists can recommend detoxification strategies such as chelation therapy, dietary changes, or supplements to help the body eliminate these metals and reduce allergic reactions.

Vitamin D and Immune Function Testing

Vitamin D is an essential nutrient for regulating immune function; a deficiency has been linked to an increased risk of allergies. Vitamin D modulates the immune response, helping to prevent overreactions that lead to allergies.

Popular labs: 

Understanding Functional Medicine Lab Results

Understanding and interpreting lab results is essential to creating effective treatment plans for allergists utilizing functional medicine. Several key biomarkers can provide insights into the root causes of allergic reactions. Please note that all lab results should always be read and interpreted by a qualified healthcare professional.

  • Inflammatory markers such as calprotectin or zonulin, which indicate gut inflammation or intestinal permeability, are also vital. High levels suggest that addressing gut health could reduce allergic symptoms.
  • IgE and IgG antibody levels 
  • Nutritional markers, such as vitamin D levels, are also important. Vitamin D regulates the immune system, and deficiencies can exacerbate allergic conditions.

By examining these biomarkers, allergists can connect lab results to functional interventions such as dietary adjustments, gut-healing protocols, or immune support strategies.

Integrating Lab Findings into Treatment Plans

Allergists use functional medicine lab data to personalize treatment for their patients. Once key biomarkers are identified, targeted interventions can be implemented. 

Examples: 

  • If food sensitivity testing reveals triggers, an allergist might recommend an elimination diet to remove problem foods and reduce inflammation.
  • For gut imbalances, allergists may suggest probiotics, prebiotics, or specific supplements to restore microbial balance and improve immune function. 
  • If vitamin or mineral deficiencies are detected, supplements like vitamin D or omega-3 fatty acids can be recommended to support immune regulation.

Lifestyle modifications are also important, such as improving sleep, managing stress, or reducing exposure to environmental allergens, which can help reduce allergic reactions. By integrating lab findings into treatment plans, allergists can address the root causes of allergies, providing patients with more effective, long-term relief.

Benefits of Functional Medicine Labs for Allergists and Patients

Functional medicine labs offer allergists a more detailed and holistic view of a patient's health, leading to improved diagnostic accuracy, especially for complex or chronic allergy cases. Traditional allergy tests often focus solely on immediate immune responses, but functional labs delve deeper, examining factors like gut health, food sensitivities, and environmental exposures. 

 It highlights a patient case study where traditional allergy testing was inconclusive but a specific IgG Food Panel identified food sensitivities and gut imbalances.
  • Example: A patient with persistent eczema may test negative for common allergens using conventional methods, but functional lab tests like the IgG Food Panel or GI-MAP could reveal underlying food sensitivities or gut imbalances contributing to the condition. Once these root causes are identified, targeted interventions can lead to significant improvements.

Personalized Treatment for Lasting Results

One of functional medicine labs' main benefits is their ability to guide personalized treatment plans. By using lab results to identify specific triggers and imbalances, allergists can tailor their recommendations to each patient’s unique needs. 

For instance, a patient with food intolerances uncovered by MRT testing may be advised to follow an elimination diet. At the same time, someone with gut dysbiosis may benefit from probiotics and gut-healing supplements.

This personalized approach often leads to more effective, long-lasting results, especially for chronic allergy sufferers. Rather than simply managing symptoms with medications, patients receive targeted treatments that address the underlying causes of their allergies, leading to improved overall health and fewer allergy flare-ups over time.

[signup]

Key Takeaways

  • Functional medicine labs help allergists identify the root causes of allergies, such as gut health imbalances, food sensitivities, and environmental exposures.
  • Comprehensive gut microbiome testing provides insights into bacterial balance, inflammation, and other gut-related factors that contribute to allergies.
  • Food sensitivity and intolerance testing identify delayed immune responses to foods that may worsen allergies like eczema and asthma.
  • Environmental allergen testing detects mold, pollen, and other environmental triggers, helping allergists address chronic exposures.
  • IgE and IgG antibody testing distinguishes between immediate and delayed allergic reactions, offering a more complete picture of immune responses.
  • Organic Acid Testing (OAT) helps identify metabolic imbalances and nutritional deficiencies that may exacerbate allergic reactions, allowing for more targeted interventions.
  • Heavy metal toxicity testing uncovers toxic metal exposure that can weaken the immune system and trigger allergies.
  • Personalized treatments based on lab results—such as dietary changes, supplements, and lifestyle modifications—lead to more effective, long-lasting relief from allergies, especially for chronic sufferers.
The information in this article is designed for educational purposes only and is not intended to be a substitute for informed medical advice or care. This information should not be used to diagnose or treat any health problems or illnesses without consulting a doctor. Consult with a health care practitioner before relying on any information in this article or on this website.

Learn more

No items found.

Lab Tests in This Article

Bertagna, B. (2024, March 7). Fueling your gut: The best foods to restore gut health. Rupa Health. https://www.rupahealth.com/post/fueling-your-gut-the-best-foods-to-restore-gut-health

Cleveland Clinic. (2022, July 7). Heavy Metal Poisoning (Heavy Metal Toxicity): Symptoms, Causes & Treatment. Cleveland Clinic. https://my.clevelandclinic.org/health/diseases/23424-heavy-metal-poisoning-toxicity

Cloyd, J. (2023a, February 23). Organic acid testing 101: A complete guide to the top 3 organic acid test. Rupa Health. https://www.rupahealth.com/post/organic-acid-testing-101-a-complete-guide-to-the-top-3-organic-acid-test

Cloyd, J. (2023b, February 28). A Functional Medicine Protocol for Leaky Gut Syndrome. Rupa Health. https://www.rupahealth.com/post/a-functional-medicine-protocol-for-leaky-gut-syndrome

Cloyd, J. (2023c, April 19). What’s the Difference Between Prebiotics vs. Probiotics vs. Postbiotics? Rupa Health. https://www.rupahealth.com/post/whats-the-difference-between-prebiotics-vs-probiotics-vs-postbiotics

Cloyd, J. (2024, September 16). Different Types of Eczema And How To Identify Them. Rupa Health. https://www.rupahealth.com/post/different-types-of-eczema-and-how-to-identify-them

Decesaris, L. (2022, August 30). 10 Signs You Should Try An Elimination Diet. Rupa Health. https://www.rupahealth.com/post/how-to-do-an-elimination-diet

DePorto, T. (2023, January 6). Omega 3’s: The Superfood Nutrient You Need To Know About. Rupa Health. https://www.rupahealth.com/post/omega-3s-the-superfood-nutrient-you-need-to-know-about

Flora, S. J. S., & Pachauri, V. (2010). Chelation in Metal Intoxication. International Journal of Environmental Research and Public Health, 7(7), 2745–2788. https://doi.org/10.3390/ijerph7072745

Greenan, S. (2021, November 19). What is Functional Medicine? How Do I Find A Functional Medicine Practitioner? Rupa Health. https://www.rupahealth.com/post/what-is-functional-medicine

Khakham, C. (2023, July 11). Integrative medicine approach to asthma: Testing, dietary interventions, and natural remedies. Rupa Health. https://www.rupahealth.com/post/integrative-medicine-approach-to-asthma-testing-dietary-interventions-and-natural-remedies

Maholy, N. (2023, April 14). How to reduce stress through mind-body therapies. Rupa Health. https://www.rupahealth.com/post/how-to-reduce-stress-through-mind-body-therapies

Mirzakhani, H., Al-Garawi, A., Weiss, S. T., & Litonjua, A. A. (2014). Vitamin D and the development of allergic disease: how important is it? Clinical & Experimental Allergy, 45(1), 114–125. https://doi.org/10.1111/cea.12430

Oxford Biomedical Technologies. (n.d.). The Patented Mediator Release Test (MRT®). Oxford Biomedical Technologies, Inc. https://www.nowleap.com/the-patented-mediator-release-test/

Preston, J. (2023a, June 21). An integrative medicine approach to food allergies: Specialty testing and treatment options. Rupa Health. https://www.rupahealth.com/post/an-integrative-medicine-approach-to-food-allergies-specialty-testing-cross-contamination-and-treatment-options

Preston, J. (2023b, October 3). A functional medicine protocol for seasonal allergies. Rupa Health. https://www.rupahealth.com/post/a-functional-medicine-protocol-for-seasonal-allergies

Rupa Health. (n.d.-a). https://www.rupahealth.com/labs/comprehensive-guide-to-the-gi-map-test. Rupa Health. https://www.rupahealth.com/labs/comprehensive-guide-to-the-gi-map-test

Rupa Health. (n.d.-b). IgG Food Explorer by Diagnostic Solutions. Rupa Health. https://www.rupahealth.com/lab-tests/diagnostic-solutions-igg-food-explorer

Rupa Health. (n.d.-c). Metals Combo Test by Quicksilver Scientific. Rupa Health. https://www.rupahealth.com/lab-tests/quicksilver-metals-combo-test

Rupa Health. (n.d.-d). Organic Acids (OAT) by Mosaic Diagnostics (formerly Great Plains). Rupa Health. https://www.rupahealth.com/lab-tests/mosaic-diagnostics-organic-acids-oat

Rupa Health. (n.d.-e). Vitamin D, 25-OH, Total by Access Medical Laboratories. Rupa Health. https://www.rupahealth.com/lab-tests/access-medical-labs-vitamin-d-25-oh-total

Rupa Health. (2020a). Alletess Medical Laboratory. Rupa Health. https://www.rupahealth.com/lab-companies/alletess-medical-laboratory

Rupa Health. (2020b). Comprehensive Stool Analysis by Doctor’s Data. Rupa Health. https://www.rupahealth.com/lab-tests/doctors-data-comprehensive-stool-analysis

Rupa Health. (2020c). Cyrex Laboratories. Rupa Health. https://www.rupahealth.com/lab-companies/cyrex-laboratories

Rupa Health. (2020d). ELISA / ACT Biotechnologies. Rupa Health. https://www.rupahealth.com/lab-companies/elisa-act-biotechnologies

Rupa Health. (2020e). Urine Toxic Metals - Timed by Doctor’s Data. Rupa Health. https://www.rupahealth.com/lab-tests/doctors-data-urine-toxic-metals-timed

Rupa Health. (2020f). Vitamin D by Mosaic Diagnostics (formerly Great Plains). Rupa Health. https://www.rupahealth.com/lab-tests/mosaic-diagnostics-vitamin-d-blood-spot

Rupa Health. (2023). MycoTOX Profile (Mold Exposure) | Rupa Health Patient Help Center. Rupahealth.com. https://support.rupahealth.com/en/articles/8552784-mycotox-profile-mold-exposure

Rupa University. (2020). The Organic Acids Test: Key Insights for Clinical Practice. Rupauniversity.com. https://www.rupauniversity.com/live-classes/the-organic-acids-test-key-insights-for-clinical-practice

Shamji, M. H., Valenta, R., Jardetzky, T., Verhasselt, V., Durham, S. R., Würtzen, P. A., & van Neerven, R. J. J. (2021). The role of allergen‐specific IgE, IgG and IgA in allergic disease. Allergy, 76(12). https://doi.org/10.1111/all.14908

Sweetnich, J. (2023, May 4). Getting to Know Vitamin D: From Testing to Supplementing and Meeting your RDA’s. Rupa Health. https://www.rupahealth.com/post/vitamin-d-101-testing-rdas-and-supplementing

Thorner, J. (2020, May 6). Partner Lab Feature: Heavy Metals Testing with Quicksilver Scientific. Rupa Health. https://www.rupahealth.com/post/partner-lab-feature-quicksilver-scientific

Yoshimura, H. (2023, September 20). Decoding High Calprotectin Levels: Causes, Implications, and Effective Treatment Strategies. Rupa Health. https://www.rupahealth.com/post/decoding-high-calprotectin-levels-causes-implications-and-effective-treatment-strategies

Order from 30+ labs in 20 seconds (DUTCH, Mosaic, Genova & More!)
We make ordering quick and painless — and best of all, it's free for practitioners.

Latest Articles

View more on Lab Education
Subscribe to the magazine for expert-written articles straight to your inbox
Join the thousands of savvy readers who get root cause medicine articles written by doctors in their inbox every week!
Thanks for subscribing!
Oops! Something went wrong while submitting the form.
Are you a healthcare practitioner?
Thanks for subscribing!
Oops! Something went wrong while submitting the form.
Subscribe to the Magazine for free to keep reading!
Subscribe for free to keep reading, If you are already subscribed, enter your email address to log back in.
Thanks for subscribing!
Oops! Something went wrong while submitting the form.
Are you a healthcare practitioner?
Thanks for subscribing!
Oops! Something went wrong while submitting the form.
Trusted Source
Rupa Health
Medical Education Platform
Visit Source
Visit Source
American Cancer Society
Foundation for Cancer Research
Visit Source
Visit Source
National Library of Medicine
Government Authority
Visit Source
Visit Source
Journal of The American College of Radiology
Peer Reviewed Journal
Visit Source
Visit Source
National Cancer Institute
Government Authority
Visit Source
Visit Source
World Health Organization (WHO)
Government Authority
Visit Source
Visit Source
The Journal of Pediatrics
Peer Reviewed Journal
Visit Source
Visit Source
CDC
Government Authority
Visit Source
Visit Source
Office of Dietary Supplements
Government Authority
Visit Source
Visit Source
National Heart Lung and Blood Institute
Government Authority
Visit Source
Visit Source
National Institutes of Health
Government Authority
Visit Source
Visit Source
Clinical Infectious Diseases
Peer Reviewed Journal
Visit Source
Visit Source
Brain
Peer Reviewed Journal
Visit Source
Visit Source
The Journal of Rheumatology
Peer Reviewed Journal
Visit Source
Visit Source
Journal of the National Cancer Institute (JNCI)
Peer Reviewed Journal
Visit Source
Visit Source
Journal of Cardiovascular Magnetic Resonance
Peer Reviewed Journal
Visit Source
Visit Source
Hepatology
Peer Reviewed Journal
Visit Source
Visit Source
The American Journal of Clinical Nutrition
Peer Reviewed Journal
Visit Source
Visit Source
The Journal of Bone and Joint Surgery
Peer Reviewed Journal
Visit Source
Visit Source
Kidney International
Peer Reviewed Journal
Visit Source
Visit Source
The Journal of Allergy and Clinical Immunology
Peer Reviewed Journal
Visit Source
Visit Source
Annals of Surgery
Peer Reviewed Journal
Visit Source
Visit Source
Chest
Peer Reviewed Journal
Visit Source
Visit Source
The Journal of Neurology, Neurosurgery & Psychiatry
Peer Reviewed Journal
Visit Source
Visit Source
Blood
Peer Reviewed Journal
Visit Source
Visit Source
Gastroenterology
Peer Reviewed Journal
Visit Source
Visit Source
The American Journal of Respiratory and Critical Care Medicine
Peer Reviewed Journal
Visit Source
Visit Source
The American Journal of Psychiatry
Peer Reviewed Journal
Visit Source
Visit Source
Diabetes Care
Peer Reviewed Journal
Visit Source
Visit Source
The Journal of the American College of Cardiology (JACC)
Peer Reviewed Journal
Visit Source
Visit Source
The Journal of Clinical Oncology (JCO)
Peer Reviewed Journal
Visit Source
Visit Source
Journal of Clinical Investigation (JCI)
Peer Reviewed Journal
Visit Source
Visit Source
Circulation
Peer Reviewed Journal
Visit Source
Visit Source
JAMA Internal Medicine
Peer Reviewed Journal
Visit Source
Visit Source
PLOS Medicine
Peer Reviewed Journal
Visit Source
Visit Source
Annals of Internal Medicine
Peer Reviewed Journal
Visit Source
Visit Source
Nature Medicine
Peer Reviewed Journal
Visit Source
Visit Source
The BMJ (British Medical Journal)
Peer Reviewed Journal
Visit Source
Visit Source
The Lancet
Peer Reviewed Journal
Visit Source
Visit Source
Journal of the American Medical Association (JAMA)
Peer Reviewed Journal
Visit Source
Visit Source
Pubmed
Comprehensive biomedical database
Visit Source
Visit Source
Harvard
Educational/Medical Institution
Visit Source
Visit Source
Cleveland Clinic
Educational/Medical Institution
Visit Source
Visit Source
Mayo Clinic
Educational/Medical Institution
Visit Source
Visit Source
The New England Journal of Medicine (NEJM)
Peer Reviewed Journal
Visit Source
Visit Source
Johns Hopkins
Educational/Medical Institution
Visit Source
Visit Source

Hey practitioners! 👋 Join Dr. Chris Magryta and Dr. Erik Lundquist for a comprehensive 6-week course on evaluating functional medicine labs from two perspectives: adult and pediatric. In this course, you’ll explore the convergence of lab results across different diseases and age groups, understanding how human lab values vary on a continuum influenced by age, genetics, and time. Register Here! Register Here.

Hey practitioners! 👋 Join Dr. Terry Wahls for a 3-week bootcamp on integrating functional medicine into conventional practice, focusing on complex cases like Multiple Sclerosis. Learn to analyze labs through a functional lens, perform nutrition-focused physical exams, and develop personalized care strategies. Register Here.