Patient Care
|
January 20, 2025

Top 10 Best Allergy Medicines for Quick Relief

Written By
Medically Reviewed by
Dr. Ayesha Bryant MSPH, MD
Updated On
January 28, 2025

More than 100 million people face the challenges of allergy symptoms every year, from relentless sneezing to itchy, watery eyes. Finding relief that truly works can feel daunting, especially when symptoms disrupt your daily routine. With so many allergy medications available, it’s important to understand your options to choose the one that fits your needs. 

Whether you’re looking for something to manage seasonal allergies or a solution for ongoing sensitivities, knowing what each medication offers can make a big difference. This article breaks down the top allergy medicines, covering how they work, their benefits, and any potential side effects so you can find the relief you need quickly and confidently.

[signup]

Understanding Allergies

Allergies are an overreaction of the immune system to substances that are typically harmless to most people. These substances, known as allergens, can trigger the body to release chemicals like histamine, leading to uncomfortable symptoms. While allergies can vary in severity, they are a common condition affecting millions worldwide.

Common Causes and Triggers of Allergies

Allergies can be triggered by a wide variety of substances, which are generally grouped into a few main categories:

  • Environmental Allergens: Pollen, dust mites, mold spores, and pets are among the most common triggers for seasonal and indoor allergies.
  • Food Allergens: Common foods that cause allergic reactions include peanuts, shellfish, eggs, and dairy products.
  • Insect Allergens: Stings or bites from insects like bees, wasps, or ants can cause allergic responses.
  • Chemical Allergens: Certain fragrances, cleaning products, or personal care items may trigger skin or respiratory reactions.
  • Medications: Some individuals may react to drugs such as antibiotics, pain relievers, or other medications, leading to symptoms such as hives or swelling.

Understanding what triggers your allergies is key to managing them effectively and avoiding exposure whenever possible.

Symptoms That May Require Medication

Allergic reactions can manifest in various ways, depending on the allergen and the individual’s sensitivity. Some symptoms may be mild and easily manageable, while others can significantly impact daily life or require immediate attention. Common symptoms that often lead people to seek medication include:

  • Respiratory Symptoms: Sneezing, nasal congestion, runny nose, and coughing are frequent respiratory complaints, especially with pollen or dust allergies.
  • Eye Symptoms: Red, itchy, or watery eyes are a hallmark of many allergic responses.
  • Skin Symptoms: Symptoms such as hives, itching, or eczema flare-ups can occur after contact with allergens like certain foods, plants, or chemicals.
  • Systemic Symptoms: Allergies may appear organ-specific but are systemic, with the same allergen causing varied reactions over time. T cells drive immune responses, influenced by systemic and organ-level factors.

In some cases, severe reactions, such as swelling of the throat or anaphylaxis, may occur, requiring emergency medical treatment. 

Types of Allergy Medicines

Allergy relief comes in many forms, from quick over-the-counter options to long-term prescription treatments and natural remedies. Understanding these choices can help you find the best solution for your symptoms.

Over-the-counter (OTC) Options

Over-the-counter (OTC) medications are a popular choice for those seeking quick and accessible relief from allergy symptoms. 

Antihistamines like loratadine combat sneezing, itchy eyes, and runny noses. These block histamine, a chemical that triggers allergy symptoms, and are effective for seasonal and year-round allergies.

For nasal congestion, decongestants such as Sudafed can reduce swelling in the nasal passages, improving airflow and alleviating discomfort. 

Nasal sprays like Flonase, a corticosteroid, are another effective option, helping to reduce inflammation and manage symptoms such as congestion and sneezing. 

Non-medicated saline sprays are also available for gentle, side effect-free relief by flushing out allergens and hydrating nasal passages.

Prescription Allergy Treatments

Prescription treatments may provide relief for those with severe or chronic allergy symptoms. 

Immunotherapy, such as allergy shots or sublingual tablets, is a long-term solution designed to desensitize the immune system to specific allergens over time. This approach can be particularly effective for individuals with significant or persistent symptoms not well-managed with OTC options.

Prescription-strength antihistamines are another avenue for symptom control, offering more potent and consistent relief for conditions such as chronic rhinitis or hives. These medications are typically tailored to the individual’s needs and may be combined with other treatments for optimal results.

Natural and Homeopathic Remedies

Natural and homeopathic remedies are appealing alternatives for those looking to complement conventional treatments or avoid medications. 

Herbal supplements like butterbur and quercetin may support immune health and provide mild allergy symptom relief. Consulting a healthcare provider before starting them is important, as interactions with other medications can occur.

Saline nasal rinses, commonly used with neti pots, offer a natural way to flush allergens and mucus from the nasal passages. 

These rinses help reduce irritation and congestion without the side effects of medicated options, making them a safe and effective addition to an allergy management routine.

By understanding the wide range of allergy medicines available, from OTC solutions to prescription treatments and natural remedies, you can select the option that best suits your needs and helps you manage your symptoms effectively.

How to Choose the Best Allergy Medicine

Choosing the right allergy medicine can improve your ability to manage your symptoms effectively. By evaluating your individual needs and seeking professional guidance, you can find a solution that works best for you.

Factors to Consider

Several factors should be weighed when selecting an allergy medication. The severity of your symptoms is a key consideration. 

Mild symptoms like occasional sneezing or nasal congestion might respond well to over-the-counter options like antihistamines or nasal sprays. However, more severe or persistent symptoms could require prescription treatments or a combination of therapies.

Your age and overall health are also crucial. Medications are often formulated with specific groups in mind, and what works for one person might not be suitable for another. Children, older adults, and those with certain medical conditions may require specialized recommendations.

Another important factor is the potential side effects of the medication. For example, antihistamines can sometimes cause drowsiness, and decongestants may increase heart rate. Knowing these risks can help you choose a safe and effective option.

Consult with a Doctor or Pharmacist

Consulting a healthcare professional is important when choosing the best allergy medication. Doctors and pharmacists can provide personalized advice based on your symptoms, health history, and current medications. They can also help you weigh the benefits and risks of various options. During your consultation, consider asking specific questions such as:

  • What is the most suitable medication for my symptoms?
  • Are there any potential side effects or interactions with my current medications?
  • How long should I take this medication, and are there any long-term concerns?

By considering these factors and seeking professional guidance, you can confidently choose the allergy medicine that best meets your needs and improves your quality of life.

Tips for Managing Allergies Beyond Medicine

While medications can be highly effective in controlling allergy symptoms, combining them with lifestyle adjustments and preventive measures can significantly improve your quality of life. Taking steps to minimize exposure to allergens and adopting healthy habits can make a noticeable difference.

Preventing Exposure to Allergens

Reducing contact with allergens is a crucial strategy for managing symptoms. Keeping your home clean can help eliminate common triggers like dust and pet dander. Regular vacuuming with a HEPA filter, washing bedding in hot water, and using air purifiers can make your living environment more allergen-free. 

Additionally, being mindful of seasonal changes, such as monitoring pollen counts and keeping windows closed during peak allergy seasons, can reduce exposure to outdoor allergens. Showering and changing clothes after outdoor activities can also help remove pollen from your skin and hair.

Lifestyle Adjustments

Simple changes to your daily routine can help you manage allergies more effectively. A balanced diet rich in nutrients, such as vitamins C and E, supports normal immune responses while staying hydrated helps keep mucous membranes moist and better equipped to flush out allergens.

Managing stress is equally important, as it can impact immune function and exacerbate allergy symptoms. Relaxation techniques, regular exercise, and adequate sleep can help reduce stress levels and improve overall well-being.

Combining these tips with the right medication can create a comprehensive allergy management plan that minimizes symptoms and enhances your quality of life.

[signup]

Key Takeaways

  • Allergy medications range from over-the-counter antihistamines and decongestants to prescription immunotherapy and nasal sprays; each offering targeted relief depending on the severity and type of symptoms.
  • Over-the-counter options like Loratadine and Flonase are widely used for mild to moderate symptoms, while severe or chronic allergies may require prescription-strength treatments or immunotherapy.
  • Natural remedies such as saline rinses or supplements like butterbur can complement traditional treatments but should be used cautiously and with medical advice to avoid potential interactions.
  • Choosing the right allergy medication depends on factors like symptom severity, age, health conditions, and side effects, so a professional consultation with a doctor or pharmacist is essential.
  • Combining medications with lifestyle changes—such as reducing allergen exposure, maintaining a clean environment, and managing stress—can significantly enhance symptom management and improve quality of life.
The information in this article is designed for educational purposes only and is not intended to be a substitute for informed medical advice or care. This information should not be used to diagnose or treat any health problems or illnesses without consulting a doctor. Consult with a health care practitioner before relying on any information in this article or on this website.

Learn more

No items found.

Lab Tests in This Article

No lab tests!

Aghababaei, F., & Hadidi, M. (2023). Recent Advances in Potential Health Benefits of Quercetin. Pharmaceuticals, 16(7), 1020. https://doi.org/10.3390/ph16071020

Allergens. (n.d.). National Institute of Environmental Health Sciences. https://www.niehs.nih.gov/health/topics/agents/allergens

Allergies & Sensitivities - Environmental Testing. (n.d.). Rupa Health. https://www.rupahealth.com/health-categories/allergies-sensitivities-environmental

Başaran, N., Paslı, D., & Başaran, A. A. (2022). Unpredictable adverse effects of herbal products. Food and Chemical Toxicology, 159, 112762. https://doi.org/10.1016/j.fct.2021.112762

Cleveland Clinic. (2020, July 30). Allergic Rhinitis (Hay Fever): Symptoms, Diagnosis & Treatment. Cleveland Clinic. https://my.clevelandclinic.org/health/diseases/8622-allergic-rhinitis-hay-fever

Cleveland Clinic. (2022, December 21). Allergies: Symptoms, Reaction, Treatment & Management. Cleveland Clinic. https://my.clevelandclinic.org/health/diseases/8610-allergies

Cloyd, J. (2023, March 7). An integrative medicine approach to fatigue. Rupa Health. https://www.rupahealth.com/post/an-integrative-medicine-approach-to-fatigue

Daley-Yates, P. T., Larenas-Linnemann, D., Bhargave, C., & Verma, M. (2021). Intranasal Corticosteroids: Topical Potency, Systemic Activity and Therapeutic Index. Journal of Asthma and Allergy, Volume 14, 1093–1104. https://doi.org/10.2147/jaa.s321332

Din, L., & Lui, F. (2024). Butterbur. PubMed; StatPearls Publishing. https://pubmed.ncbi.nlm.nih.gov/30725845/

Dougherty, J. M., Alsayouri, K., & Sadowski, A. (2020). Allergy. PubMed; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK545237/

Dubey, S., Rohra, H., & Taneja, A. (2021). Assessing effectiveness of air purifiers (HEPA) for controlling indoor particulate pollution. Heliyon, 7(9), e07976. https://doi.org/10.1016/j.heliyon.2021.e07976

Eye Allergies (Conjunctivitis). (n.d.). Asthma & Allergy Foundation of America. https://aafa.org/allergies/allergy-symptoms/eye-allergy-conjunctivitis/

Farzam, K., O’Rourke, M. C., & Sabir, S. (2022, December 27). Antihistamines. PubMed; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK538188/

G. Mortuaire, L. de Gabory, M. François, G. Massé, Bloch, F., Brion, N., Jankowski, R., & Serrano, E. (2013). Rebound congestion and rhinitis medicamentosa: Nasal decongestants in clinical practice. Critical review of the literature by a medical panel. European Annals of Otorhinolaryngology, Head and Neck Diseases, 130, 3. https://doi.org/10.1016/j.anorl.2012.09.005

Gerow, S. (2024, November 20). Saline Nasal Spray: Benefits, Usage, & Safety. Rupa Health. https://www.rupahealth.com/post/saline-nasal-spray-benefits-usage-safety

Information, N. C. for B., Pike, U. S. N. L. of M. 8600 R., MD, B., & USA, 20894. (2020). Hay fever: Overview. In www.ncbi.nlm.nih.gov. Institute for Quality and Efficiency in Health Care (IQWiG). https://www.ncbi.nlm.nih.gov/books/NBK279488/

Institute for Quality and Efficiency in Health Care. (2017, July 13). Allergies: Overview. Nih.gov; Institute for Quality and Efficiency in Health Care (IQWiG). https://www.ncbi.nlm.nih.gov/books/NBK447112/

James, J. (2024, April). Allergy Facts. Asthma & Allergy Foundation of America. https://aafa.org/allergies/allergy-facts/

Jongbloed, W. M., & Brown, S. M. (2022). Allergies and Natural Alternatives. Otolaryngologic Clinics of North America, 55(5), 965–982. https://doi.org/10.1016/j.otc.2022.06.005

L Weinberg, J. (2023, March 13). What is Heart Rate Variability? Rupa Health. https://www.rupahealth.com/post/what-is-heart-rate-variability

Linton, S., Hossenbaccus, L., & Ellis, A. K. (2023). Evidence-based use of antihistamines for treatment of allergic conditions. Annals of Allergy Asthma & Immunology, 131(4), 412–420. https://doi.org/10.1016/j.anai.2023.07.019

Memon, R. J., Persaud, Y., & Savliwala, M. N. (2020). Allergy Desensitization. PubMed; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK535367/

Nakajima, R., Morita, N., Watanabe, F., & Kosuge, Y. (2022). Association Between Inappropriate Use of Over-The-Counter Drugs for Allergic Rhinitis and Side Effects on the Central Nervous system—a Cross-Sectional Survey. Patient Preference and Adherence, Volume 16, 3111–3118. https://doi.org/10.2147/ppa.s388226

National Cancer Institute. (2019). NCI Dictionary of Cancer Terms. National Cancer Institute; Cancer.gov. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/t-cell

Overview: Allergic contact dermatitis. (2024, February). Nih.gov; Institute for Quality and Efficiency in Health Care (IQWiG). https://www.ncbi.nlm.nih.gov/books/n/pmh_iqwig/i2578/

Overview: Allergies to animals. (2023, August 14). Nih.gov; Institute for Quality and Efficiency in Health Care (IQWiG). https://www.ncbi.nlm.nih.gov/books/n/pmh_iqwig/i2039/

Overview: Dust mite allergies. (2023, August 17). Nih.gov; Institute for Quality and Efficiency in Health Care (IQWiG). https://www.ncbi.nlm.nih.gov/books/n/pmh_iqwig/i2669/

Overview: Food allergies. (2023, August 21). Nih.gov; Institute for Quality and Efficiency in Health Care (IQWiG). https://www.ncbi.nlm.nih.gov/books/n/pmh_iqwig/i2297/

Overview: Insect venom allergies. (2023, June 14). Nih.gov; Institute for Quality and Efficiency in Health Care (IQWiG). https://www.ncbi.nlm.nih.gov/books/n/pmh_iqwig/i2617/

Papadopoulos, N. G., & Guibas, G. V. (2016). Rhinitis Subtypes, Endotypes, and Definitions. Immunology and Allergy Clinics of North America, 36(2), 215–233. https://doi.org/10.1016/j.iac.2015.12.001

Patel, R. H., & Mohiuddin, S. S. (2023, May 1). Biochemistry, Histamine. PubMed; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK557790/

Preston, J. (2023, October 3). A functional medicine protocol for seasonal allergies. Rupa Health. https://www.rupahealth.com/post/a-functional-medicine-protocol-for-seasonal-allergies

Pucci, S., & Incorvaia, C. (2008). Allergy as an organ and a systemic disease. Clinical and Experimental Immunology, 153(Suppl 1), 1–2. https://doi.org/10.1111/j.1365-2249.2008.03712.x

Saline Nasal Irrigation for Upper Respiratory Conditions. (2009). American Family Physician, 80(10), 1117. https://pmc.ncbi.nlm.nih.gov/articles/PMC2778074/

Sidhu, G., & Akhondi, H. (2023). Loratadine. PubMed; StatPearls Publishing. https://pubmed.ncbi.nlm.nih.gov/31194418/

Skin Allergies. (n.d.). Asthma & Allergy Foundation of America. https://aafa.org/allergies/allergy-symptoms/skin-allergies/

Stanford, J. (2024, March 19). Mastering Healthy Eating on a Budget: Practical Tips and Strategies. Rupa Health. https://www.rupahealth.com/post/mastering-healthy-eating-on-a-budget-practical-tips-and-strategies

Sweetnich, J. (2023a, May 8). The Antioxidant Powerhouse: Exploring Testing, Health Benefits, and Sources of Vitamin E. Rupa Health. https://www.rupahealth.com/post/vitamin-e-101

Sweetnich, J. (2023b, May 9). How to make sure your patients are getting enough vitamin C in their diet: Understanding testing, rdas, and the benefits of supplementation. Rupa Health. https://www.rupahealth.com/post/vitamin-c-101

Warrington, R., Silviu-Dan, F., & Wong, T. (2018). Drug allergy. Allergy, Asthma & Clinical Immunology, 14(S2). https://doi.org/10.1186/s13223-018-0289-y

Weinberg, J. (2023, December 19). The Science of Sleep: Functional Medicine for Restorative Sleep. Rupa Health. https://www.rupahealth.com/post/the-science-of-sleep-functional-medicine-for-restorative-sleep

Weinberg, J. L. (2022, July 28). Dry mouth and eyes are the first signs of this autoimmune disease. Rupa Health. https://www.rupahealth.com/post/what-is-sjogrens

Weinberg, J. L. (2023, September 18). Integrative Dermatology Approach to Urticaria (Hives). Rupa Health. https://www.rupahealth.com/post/integrative-dermatology-approach-to-urticaria-hives

Williams, S. P., & Swift, A. C. (2023). Nasal sprays: commonly used medications that are often misunderstood. British Journal of Hospital Medicine (London, England: 2005), 84(10), 1–8. https://doi.org/10.12968/hmed.2023.0212

Yoshimura, H. (2023, November 7). The remarkable power of exercise on our health: A comprehensive overview. Rupa Health. https://www.rupahealth.com/post/the-remarkable-power-of-exercise-on-our-health-a-comprehensive-overview

Order from 30+ labs in 20 seconds (DUTCH, Mosaic, Genova & More!)
We make ordering quick and painless — and best of all, it's free for practitioners.

Latest Articles

View more on Patient Care
Subscribe to the magazine for expert-written articles straight to your inbox
Join the thousands of savvy readers who get root cause medicine articles written by doctors in their inbox every week!
Thanks for subscribing!
Oops! Something went wrong while submitting the form.
Are you a healthcare practitioner?
Thanks for subscribing!
Oops! Something went wrong while submitting the form.
Subscribe to the Magazine for free to keep reading!
Subscribe for free to keep reading, If you are already subscribed, enter your email address to log back in.
Thanks for subscribing!
Oops! Something went wrong while submitting the form.
Are you a healthcare practitioner?
Thanks for subscribing!
Oops! Something went wrong while submitting the form.

Hey practitioners! 👋 Join Dr. Chris Magryta and Dr. Erik Lundquist for a comprehensive 6-week course on evaluating functional medicine labs from two perspectives: adult and pediatric. In this course, you’ll explore the convergence of lab results across different diseases and age groups, understanding how human lab values vary on a continuum influenced by age, genetics, and time. Register Here! Register Here.