Over one million women in the United States transition into menopause every year. Menopause, characterized by a decrease in estrogen and progesterone levels, is a phase in a woman's life that signifies the end of menstrual cycles. While menopause is a natural part of aging, the symptoms associated with it can significantly impact a woman's quality of life.
Functional medicine practitioners take a personalized medicine approach to menopause, aiming to address the root causes of symptoms and restore balance to the body. Herbal medicine, with its long history of use around the world, offers an evidence-based yet unconventional perspective to managing menopause.
[signup]
Understanding Menopause and Its Symptoms
Menopause is a natural biological process that marks the end of a woman's reproductive years. The transition typically occurs in the late 40s or early 50s, although the age of onset can vary. Menopause is characterized by the conclusion of menstruation for at least 12 consecutive months.
Physiological Causes
During menopause, the decrease in ovarian follicles leads to gradually lower estrogen production. More specifically, follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels rise as estrogen no longer blocks them. This process causes the endometrial lining to decrease, ceasing ovulation and the menstruation cycle.
Common Symptoms
Symptoms typically start in the perimenopause phase before menopause. These early hormonal shifts can lead to a number of physical and psychological symptoms in a woman's body, such as hot flashes, missed periods, sleep disturbances, night sweats, mood imbalance, vaginal dryness, and changes in libido. The decline in estrogen levels can also affect body temperature regulation, metabolism, and bone health.
Herbal Medicine: An Overview
Herbal medicine, also known as botanical medicine or phytotherapy, has been a fundamental component of traditional and complementary medicine practices for centuries. It involves using plants or plant extracts to treat or prevent conditions including but not limited to digestive disorders, respiratory issues, skin problems, and hormonal imbalances. Botanicals are often chosen for specific properties, such as anti-inflammatory, antioxidant, or hormone-regulating effects, to target the root cause of a problem.
In the context of menopause, herbal medicine offers a patient-centric approach to symptom management. Many herbs contain phytoestrogens, plant compounds that mimic the effects of estrogen in the body. These plant-derived nutrients can be a part of a comprehensive regimen to alleviate symptoms such as hot flashes, night sweats, and vaginal dryness by providing a natural source of estrogen-like compounds. Aligned with functional medicine principles, herbs can also target underlying causes of illness beyond symptoms and support overall health and well-being.
Popular Herbs for Menopause Symptom Management
While many herbs are popular, here are the top 5 most commonly used for menopause:
Black Cohosh
Black cohosh is one of the best-known herbs for managing menopause symptoms. Research shows that the active components, N-methylserotonin and triterpenoid isolates, could act as partial agonists to serotonin and GABA receptors. This interaction may explain its benefits for hot flashes and mood. Typical doses (20-40 mg) have also been linked to a reduction in depression and anxiety in menopausal and perimenopausal women.
Red Clover
Red clover is another herb often used to alleviate menopause symptoms, thanks to its isoflavone content. Isoflavones are plant compounds that mimic the effects of estrogen in the body. Several studies have suggested that red clover may help reduce the frequency and severity of hot flashes and improve the overall quality of life in menopausal women.
Dong Quai
Dong quai has been a mainstay in Traditional Chinese Medicine to balance hormones and improve menopause symptoms. However, scientific evidence supporting its effectiveness is limited and inconclusive. Some studies have suggested that dong quai may help alleviate menopause symptoms in combination with other herbs, but more research is needed to confirm its benefits and safety profile.
Sage
Sage is considered to reduce certain symptoms, such as night sweats associated with menopause. It is believed that sage may help regulate body temperature and reduce excessive sweating. Sage also has antioxidant properties, which may help protect against oxidative stress and excess inflammation.
St. John’s Wort
St. John's wort is commonly used to manage mood swings and depression associated with menopause. It is believed that St. John's wort may help increase levels of neurotransmitters such as serotonin, which can improve depression. However, St. John's wort can interact with a variety of medications, including antidepressants, birth control pills, and blood thinners, so it is critical to consult with a healthcare provider before using this herb.
Integrating Herbal Medicine into Menopause Management
Herbal medicine can be a beneficial component of a comprehensive menopause management plan, offering medically-backed options for symptom relief. Here are some key considerations for incorporating herbal medicine into menopause regimen:
Consultation with Healthcare Providers
Before starting any herbal treatment regimen, it is essential to consult with a multidisciplinary care team that includes one or two experts in herbal medicine’s therapeutic properties. A functional medicine practitioner can help determine the right herbs and dosages for individual needs using specialized lab testing and monitoring for any potential interactions with prescriptions or supplements.
Personalized Treatment Plan
Every woman experiences menopause differently, so it is important to tailor the herbal treatment plan to a patient’s treatment goals. A functional medicine practitioner can help develop a personalized regimen that addresses specific symptoms and concerns, taking into account the potential use of hormonal therapy as well as diet and lifestyle.
Monitoring and Adjustment
Once a patient has started an herbal treatment regimen, healthcare providers should be advised to monitor symptoms and progress closely. If patients experience any adverse effects or if symptoms worsen, it may be necessary to adjust the herbal remedies or dosage. Regular follow-up visits with a functional medicine practitioner help ensure that the treatment plan remains effective and safe.
Potential Side Effects and Interactions
While herbal medicine can offer natural relief from menopause symptoms, there are potential side effects and interactions. Here are the associated risks of using those same herbs for menopause symptom management:
Black Cohosh
Black cohosh is generally well-tolerated, but in some cases, it may cause gastrointestinal upset, headaches, or dizziness. There have been reports of liver problems associated with black cohosh, so it is important to consider whether it is the right choice for a patient with a history of such disorders. Some studies have shown a weak link between this herb and liver injury, but more research is needed to discern the concrete relationship between the two.
Red Clover
Red clover isoflavones are generally safe for most women but may cause mild side effects such as nausea, headache, or muscle aches. Some studies suggest that the coumarins in red clover may increase the risk of bleeding, so patients should exercise caution if taking it with anticoagulants or blood-thinning medications.
Dong Quai
Dong quai is generally considered safe when used in moderate amounts, but it may cause side effects such as gastrointestinal upset, skin irritation, or sensitivity to sunlight. Dong quai has been shown to prolong prothrombin time and influence platelet activity, so patients on blood thinners or anticoagulants should be aware of this potential interaction.
Sage
Sage is considered safe for most people when used in culinary amounts, but concentrated sage extracts or supplements may cause side effects such as dizziness, rapid heartbeat, or allergic reactions. Sage should be used with caution if patients have a history of seizures.
St. John's Wort
St. John's wort is notorious for its long list of drug-herb interactions, including antidepressants, birth control pills, and blood thinners. It can reduce the effectiveness of these medications and may also cause side effects such as skin sensitivity to sunlight, gastrointestinal upset, or allergic reactions.
Given the potential for side effects and interactions, patients should seek guidance from their healthcare team when using herbal remedies for menopause symptom management. A functional medicine practitioner can help determine the right herbs and dosages for their specific needs and monitor for any adverse effects or interactions with other treatments. Individualized treatment approaches are fundamental to ensuring the safety and effectiveness of herbal medicine in managing menopause symptoms.
Lifestyle Modifications to Complement Herbal Medicine
In addition to herbal medicine, other integrative medicine modalities can support symptom relief during menopause. Here are some lifestyle changes that can complement herbal medicine in managing menopause:
Dietary Changes
A balanced diet rich in fruits, vegetables, whole grains, and lean proteins can support hormonal balance and overall health during menopause. Some foods, such as soy products, flaxseeds, and legumes, contain phytoestrogens that may help alleviate menopause symptoms. Avoiding trigger foods, such as caffeine, alcohol, and spicy foods, which can worsen hot flashes and other symptoms, is also recommended.
Physical Activity
Regular exercise has been shown to reduce stress and improve mood, which can help with menopause symptoms. It is advised to engage in at least 30 minutes of moderate-intensity exercise most days.
Stress Reduction
Stress can exacerbate menopause symptoms such as hot flashes and mood. Stress-reducing techniques such as meditation, deep breathing exercises, yoga, or mindfulness can help manage stress levels and improve overall well-being during menopause.
Rejuvenating Sleep
Sleep disturbances are common during menopause, but maintaining a healthy sleep routine can help alleviate these symptoms. Establishing a regular sleep schedule, creating a relaxing bedtime routine, considering hormone replacement therapy, and ensuring that the sleep environment is conducive to restful sleep can all improve sleep quality during menopause.
[signup]
Key Takeaways
Herbal medicine offers valuable benefits as part of an individualized approach to managing menopausal symptoms. While herbal remedies can be effective, it is crucial patients consult with their functional medicine practitioner for personalized care. By integrating herbal medicine into a comprehensive menopause management plan and fostering open communication with an interdisciplinary healthcare team, women can navigate this natural transition with confidence, achieving optimal health and well-being.
Over one million women in the United States transition into menopause every year. Menopause, characterized by a decrease in estrogen and progesterone levels, is a phase in a woman's life that signifies the end of menstrual cycles. While menopause is a natural part of aging, the symptoms associated with it can significantly impact a woman's quality of life.
Functional medicine practitioners take a personalized medicine approach to menopause, aiming to address the root causes of symptoms and restore balance to the body. Herbal medicine, with its long history of use around the world, offers a perspective that may help manage menopause symptoms.
[signup]
Understanding Menopause and Its Symptoms
Menopause is a natural biological process that marks the end of a woman's reproductive years. The transition typically occurs in the late 40s or early 50s, although the age of onset can vary. Menopause is characterized by the conclusion of menstruation for at least 12 consecutive months.
Physiological Causes
During menopause, the decrease in ovarian follicles leads to gradually lower estrogen production. More specifically, follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels rise as estrogen no longer blocks them. This process causes the endometrial lining to decrease, ceasing ovulation and the menstruation cycle.
Common Symptoms
Symptoms typically start in the perimenopause phase before menopause. These early hormonal shifts can lead to a number of physical and psychological symptoms in a woman's body, such as hot flashes, missed periods, sleep disturbances, night sweats, mood imbalance, vaginal dryness, and changes in libido. The decline in estrogen levels can also affect body temperature regulation, metabolism, and bone health.
Herbal Medicine: An Overview
Herbal medicine, also known as botanical medicine or phytotherapy, has been a fundamental component of traditional and complementary medicine practices for centuries. It involves using plants or plant extracts to support health and well-being. Botanicals are often chosen for specific properties, such as anti-inflammatory, antioxidant, or hormone-supporting effects, to help maintain balance in the body.
In the context of menopause, herbal medicine offers a patient-centric approach to symptom management. Many herbs contain phytoestrogens, plant compounds that mimic the effects of estrogen in the body. These plant-derived nutrients can be a part of a comprehensive regimen to help manage symptoms such as hot flashes, night sweats, and vaginal dryness by providing a natural source of estrogen-like compounds. Aligned with functional medicine principles, herbs can also support overall health and well-being.
Popular Herbs for Menopause Symptom Management
While many herbs are popular, here are the top 5 most commonly used for menopause:
Black Cohosh
Black cohosh is one of the best-known herbs for managing menopause symptoms. Research suggests that the active components, N-methylserotonin and triterpenoid isolates, may interact with serotonin and GABA receptors. This interaction may help with hot flashes and mood. Typical doses (20-40 mg) have also been linked to a reduction in depression and anxiety in menopausal and perimenopausal women.
Red Clover
Red clover is another herb often used to help manage menopause symptoms, thanks to its isoflavone content. Isoflavones are plant compounds that mimic the effects of estrogen in the body. Several studies have suggested that red clover may help reduce the frequency and severity of hot flashes and improve the overall quality of life in menopausal women.
Dong Quai
Dong quai has been a mainstay in Traditional Chinese Medicine to support hormone balance and improve menopause symptoms. However, scientific evidence supporting its effectiveness is limited and inconclusive. Some studies have suggested that dong quai may help alleviate menopause symptoms in combination with other herbs, but more research is needed to confirm its benefits and safety profile.
Sage
Sage is considered to help with certain symptoms, such as night sweats associated with menopause. It is believed that sage may help regulate body temperature and reduce excessive sweating. Sage also has antioxidant properties, which may help protect against oxidative stress and excess inflammation.
St. John’s Wort
St. John's wort is commonly used to help manage mood swings and feelings of sadness associated with menopause. It is believed that St. John's wort may help increase levels of neurotransmitters such as serotonin, which can improve mood. However, St. John's wort can interact with a variety of medications, including antidepressants, birth control pills, and blood thinners, so it is critical to consult with a healthcare provider before using this herb.
Integrating Herbal Medicine into Menopause Management
Herbal medicine can be a beneficial component of a comprehensive menopause management plan, offering options for symptom relief. Here are some key considerations for incorporating herbal medicine into menopause regimen:
Consultation with Healthcare Providers
Before starting any herbal treatment regimen, it is essential to consult with a multidisciplinary care team that includes one or two experts in herbal medicine’s therapeutic properties. A functional medicine practitioner can help determine the right herbs and dosages for individual needs using specialized lab testing and monitoring for any potential interactions with prescriptions or supplements.
Personalized Treatment Plan
Every woman experiences menopause differently, so it is important to tailor the herbal treatment plan to a patient’s treatment goals. A functional medicine practitioner can help develop a personalized regimen that addresses specific symptoms and concerns, taking into account the potential use of hormonal therapy as well as diet and lifestyle.
Monitoring and Adjustment
Once a patient has started an herbal treatment regimen, healthcare providers should be advised to monitor symptoms and progress closely. If patients experience any adverse effects or if symptoms worsen, it may be necessary to adjust the herbal remedies or dosage. Regular follow-up visits with a functional medicine practitioner help ensure that the treatment plan remains effective and safe.
Potential Side Effects and Interactions
While herbal medicine can offer natural relief from menopause symptoms, there are potential side effects and interactions. Here are the associated risks of using those same herbs for menopause symptom management:
Black Cohosh
Black cohosh is generally well-tolerated, but in some cases, it may cause gastrointestinal upset, headaches, or dizziness. There have been reports of liver problems associated with black cohosh, so it is important to consider whether it is the right choice for a patient with a history of such disorders. Some studies have shown a weak link between this herb and liver injury, but more research is needed to discern the concrete relationship between the two.
Red Clover
Red clover isoflavones are generally safe for most women but may cause mild side effects such as nausea, headache, or muscle aches. Some studies suggest that the coumarins in red clover may increase the risk of bleeding, so patients should exercise caution if taking it with anticoagulants or blood-thinning medications.
Dong Quai
Dong quai is generally considered safe when used in moderate amounts, but it may cause side effects such as gastrointestinal upset, skin irritation, or sensitivity to sunlight. Dong quai has been shown to prolong prothrombin time and influence platelet activity, so patients on blood thinners or anticoagulants should be aware of this potential interaction.
Sage
Sage is considered safe for most people when used in culinary amounts, but concentrated sage extracts or supplements may cause side effects such as dizziness, rapid heartbeat, or allergic reactions. Sage should be used with caution if patients have a history of seizures.
St. John's Wort
St. John's wort is notorious for its long list of drug-herb interactions, including antidepressants, birth control pills, and blood thinners. It can reduce the effectiveness of these medications and may also cause side effects such as skin sensitivity to sunlight, gastrointestinal upset, or allergic reactions.
Given the potential for side effects and interactions, patients should seek guidance from their healthcare team when using herbal remedies for menopause symptom management. A functional medicine practitioner can help determine the right herbs and dosages for their specific needs and monitor for any adverse effects or interactions with other treatments. Individualized treatment approaches are fundamental to ensuring the safety and effectiveness of herbal medicine in managing menopause symptoms.
Lifestyle Modifications to Complement Herbal Medicine
In addition to herbal medicine, other integrative medicine modalities can support symptom relief during menopause. Here are some lifestyle changes that can complement herbal medicine in managing menopause:
Dietary Changes
A balanced diet rich in fruits, vegetables, whole grains, and lean proteins can support hormonal balance and overall health during menopause. Some foods, such as soy products, flaxseeds, and legumes, contain phytoestrogens that may help manage menopause symptoms. Avoiding trigger foods, such as caffeine, alcohol, and spicy foods, which can worsen hot flashes and other symptoms, is also recommended.
Physical Activity
Regular exercise has been shown to reduce stress and improve mood, which can help with menopause symptoms. It is advised to engage in at least 30 minutes of moderate-intensity exercise most days.
Stress Reduction
Stress can exacerbate menopause symptoms such as hot flashes and mood. Stress-reducing techniques such as meditation, deep breathing exercises, yoga, or mindfulness can help manage stress levels and improve overall well-being during menopause.
Rejuvenating Sleep
Sleep disturbances are common during menopause, but maintaining a healthy sleep routine can help alleviate these symptoms. Establishing a regular sleep schedule, creating a relaxing bedtime routine, considering hormone replacement therapy, and ensuring that the sleep environment is conducive to restful sleep can all improve sleep quality during menopause.
[signup]
Key Takeaways
Herbal medicine offers potential benefits as part of an individualized approach to managing menopausal symptoms. While herbal remedies can be helpful, it is crucial patients consult with their functional medicine practitioner for personalized care. By integrating herbal medicine into a comprehensive menopause management plan and fostering open communication with an interdisciplinary healthcare team, women can navigate this natural transition with confidence, achieving optimal health and well-being.
Research explores the impact of menopause on women’s health and aging. (2022). National Institute on Aging. https://www.nia.nih.gov/news/research-explores-impact-menopause-womens-health-and-aging
Mayo Clinic. (2023). Menopause - Symptoms and causes. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/menopause/symptoms-causes/syc-20353397
Yoshimura, H. (2023). Using Functional Medicine As Personalized Medicine. Rupa Health. https://www.rupahealth.com/post/using-functional-medicine-as-personalized-medicine
Herbal Medicine. (2012). Medlineplus.gov; National Library of Medicine. https://medlineplus.gov/herbalmedicine.html
Preston, J. (2023). How to Improve Women's Reproductive Health With Lab Testing. Rupa Health. https://www.rupahealth.com/post/how-to-improve-womens-reproductive-health-with-lab-testing
Preston, J. (2023). An Integrative Medicine Approach to Managing Menopause Symptoms. Rupa Health. https://www.rupahealth.com/post/an-integrative-medicine-approach-to-managing-menopause-symptoms
DeCesaris, L. (2023). How To Test For Female Hormones: A Comprehensive Guide. Rupa Health. https://www.rupahealth.com/post/how-to-test-for-female-hormones-a-comprehensive-guide
Christie, J. (2023). An Integrative Approach to Perimenopause. Rupa Health. https://www.rupahealth.com/post/an-integrative-approach-to-perimenopause
Cloyd, J. (2023). A Root Cause Medicine Protocol For Patients With Hot Flashes: Testing, Therapeutic Diet, and Supportive Supplements. Rupa Health. https://www.rupahealth.com/post/a-root-cause-medicine-protocol-for-patients-with-hot-flashes-testing-therapeutic-diet-and-supportive-supplements
LoBisco, S. (2022). Why Does Perimenopause Rage Happen?. Rupa Health. https://www.rupahealth.com/post/why-does-perimenopause-rage-happen
Preston, J. (2023). 3 Lab Test That Can Help Address Low Libido in Menopausal Women. Rupa Health. https://www.rupahealth.com/post/3-lab-test-that-can-help-address-low-libido-in-menopausal-women
Cleveland Clinic. (2022). Phytotherapy: Definition, Research & Principles. Cleveland Clinic. https://my.clevelandclinic.org/health/drugs/22995-phytotherapy
Teeter, L. A. (2023). What is Ayurvedic Medicine?. Rupa Health. https://www.rupahealth.com/post/what-is-ayurvedic-medicine
Preston, J. (2023). The Benefits of Herbal Medicine in Managing Menopausal Symptoms. Rupa Health. https://www.rupahealth.com/post/the-benefits-of-herbal-medicine-in-managing-menopausal-symptoms
Saghafi, N., Ghazanfarpour, M., Sadeghi, R., Najarkolaei, A. H., Omid, M. G., Azad, A., Bakhtiyari, M., & Najarkolaei, E. H. (2017, January 1). Effects of phytoestrogens in Alleviating the menopausal Symptoms: A Systematic Review and Meta-Analysis. PubMed Central (PMC). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963651/
Kligler, B. (2003). Black Cohosh. American Family Physician, 68(1), 114–116. https://www.aafp.org/pubs/afp/issues/2003/0701/p114.html
Kenda, M., Glavač, N. K., Nagy, M., Sollner Dolenc, M., & On Behalf Of The Oemonom (2021). Herbal Products Used in Menopause and for Gynecological Disorders. Molecules (Basel, Switzerland), 26(24), 7421. https://doi.org/10.3390/molecules26247421
Geller, S. E., & Studee, L. (2007). Botanical and dietary supplements for mood and anxiety in menopausal women. Menopause (New York, N.Y.), 14(3 Pt 1), 541–549. https://doi.org/10.1097/01.gme.0000236934.43701.c5
Engels, G., Podraza, M., & Blumenthal, M. (n.d.). Red Clover - American Botanical Council. Herbal Gram. https://www.herbalgram.org/resources/herbalgram/issues/69/table-of-contents/article2908/
Křížová, L., Dadáková, K., Kašparovská, J., & Kašparovský, T. (2019). Isoflavones. Molecules (Basel, Switzerland), 24(6), 1076. https://doi.org/10.3390/molecules24061076
Ghazanfarpour M, Sadeghi R, Latifnejad Roudsari R, Mirzaii Najmabadi K, Mousavi Bazaz M, Abdolahian S, Khadivzadeh T. Effects of red clover on hot flash and circulating hormone concentrations in menopausal women: a systematic review and meta-analysis. Avicenna J Phytomed. 2015 Nov-Dec;5(6):498-511. PMID: 26693407; PMCID: PMC4678495.
Greenan, S. (2021). How To Incorporate Functional Medicine Labs into Your Acupuncture Practice. Rupa Health. https://www.rupahealth.com/post/how-to-become-an-acupuncturist
Dong Quai | Memorial Sloan Kettering Cancer Center. (2023). www.mskcc.org. https://www.mskcc.org/cancer-care/integrative-medicine/herbs/dong-quai
Kupfersztain C, Rotem C, Fagot R, Kaplan B. The immediate effect of natural plant extract, Angelica sinensis and Matricaria chamomilla (Climex) for the treatment of hot flushes during menopause. A preliminary report. Clin Exp Obstet Gynecol. 2003;30(4):203-6. PMID: 14664413.
Sage. (2020). NCCIH. https://www.nccih.nih.gov/health/sage
Dadfar, F., & Bamdad, K. (2019). The effect of Saliva officinalis extract on the menopausal symptoms in postmenopausal women: An RCT. International journal of reproductive biomedicine, 17(4), 287–292. https://doi.org/10.18502/ijrm.v17i4.4555
Linde K. (2009). St. John's wort - An Overview. Forschende Komplementarmedizin (2006), 16(3), 146–155. https://doi.org/10.1159/000209290
NCCIH. (2017). St. John’s Wort and Depression: In Depth. NCCIH. https://www.nccih.nih.gov/health/st-johns-wort-and-depression-in-depth
Yoshimura, H. (2023). Why More Medical Professionals are Turning Towards Functional Medicine. Rupa Health. https://www.rupahealth.com/post/why-more-medical-professionals-are-turning-towards-functional-medicine
Christie, J. (2023). 5 Functional Medicine Lab Tests To Consider For Women in Menopause. Rupa Health. https://www.rupahealth.com/post/5-functional-medicine-lab-tests-for-your-menopause-patients
Preston, J. (2023). The Benefits of Hormone Therapy for Women and How Functional Medicine Can Help. Rupa Health. https://www.rupahealth.com/post/the-benefits-of-hormone-therapy-for-women-and-how-functional-medicine-can-help
Cloyd, J. (2023). A Functional Medicine Menopause Protocol: Comprehensive Testing, Nutrition, and Supplements. Rupa Health. https://www.rupahealth.com/post/a-functional-medicine-menopause-protocol-comprehensive-testing-nutrition-and-supplements
Cloyd, J. (2023). Drug Interactions with Common Herbs and Supplements. Rupa Health. https://www.rupahealth.com/post/drug-interactions-with-common-herbs-and-supplements
Muqeet Adnan, M., Khan, M., Hashmi, S., Hamza, M., AbdulMujeeb, S., & Amer, S. (2014). Black cohosh and liver toxicity: is there a relationship?. Case reports in gastrointestinal medicine, 2014, 860614. https://doi.org/10.1155/2014/860614
Abebe W. (2019). Review of herbal medications with the potential to cause bleeding: dental implications, and risk prediction and prevention avenues. The EPMA journal, 10(1), 51–64. https://doi.org/10.1007/s13167-018-0158-2
Segal, R., & Pilote, L. (2006). Warfarin interaction with Matricaria chamomilla. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 174(9), 1281–1282. https://doi.org/10.1503/cmaj.051191
Page, R. L., 2nd, & Lawrence, J. D. (1999). Potentiation of warfarin by dong quai. Pharmacotherapy, 19(7), 870–876. https://doi.org/10.1592/phco.19.10.870.31558
Samuels, N., Finkelstein, Y., Singer, S. R., & Oberbaum, M. (2008). Herbal medicine and epilepsy: Proconvulsive effects and interactions with antiepileptic drugs. Epilepsia, 49(3), 373–380. https://doi.org/10.1111/j.1528-1167.2007.01379.x
Henderson, L., Yue, Q. Y., Bergquist, C., Gerden, B., & Arlett, P. (2002). St John's wort (Hypericum perforatum): drug interactions and clinical outcomes. British journal of clinical pharmacology, 54(4), 349–356. https://doi.org/10.1046/j.1365-2125.2002.01683.x
Phua, D. H., Zosel, A., & Heard, K. (2009). Dietary supplements and herbal medicine toxicities-when to anticipate them and how to manage them. International journal of emergency medicine, 2(2), 69–76. https://doi.org/10.1007/s12245-009-0105-z
Bedell, S., Nachtigall, M., & Naftolin, F. (2014). The pros and cons of plant estrogens for menopause. The Journal of steroid biochemistry and molecular biology, 139, 225–236. https://doi.org/10.1016/j.jsbmb.2012.12.004
Thomas, A., & Daley, A. J. (2020). Women’s views about physical activity as a treatment for vasomotor menopausal symptoms: a qualitative study. BMC Women’s Health, 20(1). https://doi.org/10.1186/s12905-020-01063-w
Mishra, N., Mishra, V. N., & Devanshi (2011). Exercise beyond menopause: Dos and Don'ts. Journal of mid-life health, 2(2), 51–56. https://doi.org/10.4103/0976-7800.92524
Cramer, H., Peng, W., & Lauche, R. (2018). Yoga for menopausal symptoms-A systematic review and meta-analysis. Maturitas, 109, 13–25. https://doi.org/10.1016/j.maturitas.2017.12.005
Johnson, T. (2022). Sleep and Menopause. WebMD. https://www.webmd.com/menopause/sleep-disorders-sleep-menopause
Schaedel, Z., Holloway, D., Bruce, D., & Rymer, J. (2021). Management of sleep disorders in the menopausal transition. Post reproductive health, 27(4), 209–214. https://doi.org/10.1177/20533691211039151
Yoshimura, H. (2024). Exploring Collaborative Opportunities Between Functional Medicine and Conventional Medical Practitioners. Rupa Health. https://www.rupahealth.com/post/exploring-collaborative-opportunities-between-functional-medicine-and-conventional-medical-practitioners