Nutrition
|
November 13, 2024

The Potential Dangers of Food Dyes

Medically Reviewed by
Updated On
November 18, 2024

Food dyes are prevalent among processed foods, as they are used to bolster the visual appeal of snacks, candy, cereals, drinks, and other shelf-stable foods. Red-40 is a type of food dye present in at least 30% of foods. While they provide allure to many food products, food dyes have several negative health implications that are crucial to understand.  

[signup]

What Are Food Dyes?

Artificial food dyes are synthetically made and widely used in food production to enhance the appearance of foods and make them more shelf-stable. In some cases, food dyes are added to colorless foods to make them more visually appealing, and in other cases, they are used to replace the color of food lost in the food production process. Yet, research evidence presents links between these dyes and adverse health effects.

Brief History of Food Dyes

Previously, foods were colored using plant-based ingredients like saffron, turmeric, and beetroot. Synthetic dyes became more common in the 19th century with the advent of processed foods, used for visual appeal and shelf stability. Regulations around synthetic food dyes have evolved over the years as questions about their safety remain at the forefront.

More than a century ago, the 1906 Pure Food and Drug Act in the United States (U.S.) significantly changed regulations around food production, including establishing the Food and Drug Administration (FDA), setting requirements around medications, and prohibiting misbranded items. 

Over the next decades, regulations regarding the production of foods and medications have continued to change, leading to stricter guidelines for public safety. It’s important to note that many countries around the world have much tighter regulations regarding artificial food dyes than the U.S.

Types of Food Dyes

There are both Natural and Artificial/Synthetic food dyes:

Natural Food Dyes

Natural food dyes are made from plants, minerals, and other naturally occurring compounds. Not only do they add color, but some also provide nutritious benefits. Here are some commonly used natural food dyes:

  • Turmeric - Its vibrant yellow color is often used in mustards, curry powder, dill pickles, and non-dairy cheeses.
  • Beetroot - Known for its red/pink hue, it is added to baked goods, drinks, and other snacks.
  • Paprika - Known for its deep rusty red color, it is made from crushed red bell peppers and is often used in deli meats, sausages, and savory snacks.
  • Saffron - A more golden yellow than turmeric, with somewhat of a milder flavor, saffron is commonly used to color rice and other grains.
  • Spinach - The green hue in spinach provides a strong green color for soups, pastas, sauces, and other ready-made foods.
  • Carrot juice - With its vibrant orange color, it is used in drinks, sauces, snacks, and fruit purees.
  • Spirulina - Using its blue-green tone, spirulina is used to color many baked goods.

Artificial/Synthetic Food Dyes

Synthetic food dyes enhance or restore lost color in food products, increase shelf stability, and promote uniformity in mass-produced products. They have gained popularity in the food industry because they are visually appealing, offer consistent color, and are affordable in large quantities.

  • Red dye number 40 (allura red) and red dye 3 have been linked to behavioral disturbances and hyperactivity in children, bladder and urinary irritation, gastrointestinal inflammation, and DNA damage that may lead to cancer formation. It is prevalent in the food supply, with statistics saying it is found in up to 30% of food products:some text
    • Candies, like gummy bears and hard candies
    • Drinks, like sodas and fruit-flavored drinks
    • Gelatins and popsicles
    • Cereals, like those that are red
    • Medications
  • Yellow dyes numbers 5 and 6 (also called tartrazine and sunset yellow) can cause allergic reactions and may worsen asthma severity in patients who have the atopic triad. It is found in similar types of foods as red 40:some text
    • Candies that are yellow on color, like lemon-flavored candies
    • Some sodas or sports drinks
    • Yellow gelatins or popsicles
    • Cereals, like those that are yellow
    • Medications
  • Blue dyes numbers 1 and 2 (brilliant blue and indigo) may cause behavioral disturbances, similar to Red 40. Its vibrant color is often attractive to children and is presented in flavors like blue raspberry and blueberry. Common sources are candies, frozen treats, sugary drinks, and medications.
  • Green dye number 3 (fast green FCF) is linked to multiple types of cancers, endocrine dysregulations, allergic reactions, and behavioral disturbances. This green dye is found in many food sources:some text
    • Candies, including gummies and hard candies
    • Drinks, including sodas, sports drinks, and other sugary, fruit-flavored drinks
    • Ice creams and other frozen desserts
    • Salad dressings and sauces
    • Medications

The Dangers of Food Dyes

While food dyes offer the benefits of visual appeal and product uniformity, they are known to cause adverse health concerns. The degree of potential risk depends upon the type of dye, the amount of dye a patient takes in, and individual sensitivity to these synthetic compounds. 

What Are the Harmful Effects of Artificial Dye?

Potential harms from food dyes vary widely.

Should You Avoid Food Dyes?

Synthetic alternative food products are rarely (if ever) more healthy than their natural counterparts. The steps involved in food processing remove beneficial nutrients and add more harmful components that can lead to significant health risks. Synthetic ingredients are usually proinflammatory, meaning their metabolism incites a cascade of inflammation within the body that can lead to organ and tissue damage.

Avoiding synthetic food dyes and instead opting for foods that contain natural food coloring helps not only eliminate harmful food ingredients but also may introduce food ingredients that have potentially beneficial effects, like turmeric (anti-inflammatory properties), spinach (phytonutrients), and carrot juice (vitamin A).

Avoiding artificial food dyes requires carefully reading the ingredients list on food labels. Look for terms that use letters, numbers, and the color of the dye, such as “Red No 40” or “Yellow No 5.” Furthermore, simply stating “artificial flavors” or even “natural flavors” indicates ingredients that aren’t spelled out by name for some reason. 

It is also important to note that manufacturers are not required to specify the amounts of food dyes in their products, so if artificial food dyes are present, it is usually best to skip the food altogether.

It isn’t clear which artificial food dye is the most dangerous. However, Red No. 40 and Yellow No. 5 may get the most attention based on their potential harms of behavioral disturbance, allergic risk, and carcinogenicity.

[signup]

Key Takeaways

  • Artificial food dyes are widely used in the food supply worldwide to enhance visual appeal, improve shelf stability, and ensure uniformity across product lines.
  • Regulations around food dye have evolved through the years and differ globally.
  • Artificial food dyes may cause many harmful health effects, like behavioral disturbances, hyperactivity, carcinogenesis, inflammation, gastrointestinal upset, hormone imbalances, and allergic reactions.
  • Natural food coloring alternatives can offer benefits beyond enhanced visual appeal. These ingredients are often plant-based and may be beneficial to other health aspects. 
  • To minimize food dyes in the diet, when choosing food products, read the food label ingredients list carefully to identify any added food dyes or colors that may be problematic.
The information provided is not intended to be a substitute for professional medical advice. Always consult with your doctor or other qualified healthcare provider before taking any dietary supplement or making any changes to your diet or exercise routine.

Learn more

No items found.

Lab Tests in This Article

No lab tests!

Achuff, J. (2024, September 17). Understanding ADHD: A Deep Dive Into the Brain’s Structure. Rupa Health. https://www.rupahealth.com/post/understanding-adhd-a-deep-dive-into-the-brains-structure

Batada A, Jacobson MF. Prevalence of Artificial Food Colors in Grocery Store Products Marketed to Children. Clin Pediatr (Phila). 2016;55(12):1113-1119. https://pubmed.ncbi.nlm.nih.gov/27270961/ 

Bertagna, B. (2024, March 7). Fueling Your Gut: The Best Foods to Restore Gut Health. Rupa Health. https://www.rupahealth.com/post/fueling-your-gut-the-best-foods-to-restore-gut-health

Bertagna, B. (2023, December 29). Saffron’s Natural Anti-Anxiety Properties and How to Consume More of It. Rupa Health. https://www.rupahealth.com/post/saffrons-natural-anti-anxiety-properties-and-how-to-consume-more-of-it

Christie, J. (2023, January 26). A Functional Medicine and Nutrition Approach to Obesity and Weight Management. Rupa Health. https://www.rupahealth.com/post/an-integrative-approach-to-obesity

Cloyd, J. (2023, April 14). How to Alleviate Gastrointestinal (GI) Symptoms Naturally Without Medication? Rupa Health. https://www.rupahealth.com/post/how-to-alleviate-gastrointestinal-gi-symptoms-naturally-without-medication

Cloyd, J. (2024, September 17). Is Green 3 Food Dye (Fast Green FCF) Safe to Consume? Rupa Health. https://www.rupahealth.com/post/is-green-3-food-dye-fast-green-fcf-safe-to-consume 

Cloyd, J. (2024, August 29). Orange B Food Dye: Is It Safe or Should You Avoid It? Rupa Health. https://www.rupahealth.com/post/orange-b-food-dye-is-it-safe-or-should-you-avoid-it

Cloyd, J. (2022, September 21). The Link Between Asthma and Gut Health. Rupa Health. https://www.rupahealth.com/post/the-link-between-asthma-and-gut-health

Cloyd, J. (2024, January 25). What Is the Gut Microbiome? Rupa Health. https://www.rupahealth.com/post/what-is-the-gut-microbiome

Coleman, E. (2024, August 13). Indigo Carmine (Blue 2): Safety, Uses, and Side Effects. Rupa Health. https://www.rupahealth.com/post/indigo-carmine-blue-2-dye-safety-uses-and-side-effects

Coleman, E. (2024, August 13). The Truth about Red Dye 40. Rupa Health. https://www.rupahealth.com/post/the-truth-about-red-dye-40

Coleman, E. (2024, August 2). Yellow 6: Understanding Its Applications and Potential Health Impacts. Rupa Health. https://www.rupahealth.com/post/yellow-6-understanding-its-applications-and-potential-health-impacts

Daglis, S. (2024, September 3). Study Finds Potential Gut Microbiome Markers Linked to Autism Spectrum Disorder. Rupa Health. https://www.rupahealth.com/post/potential-gut-microbiome-markers-linked-to-autism-spectrum-disorder

Khakham, C. (2023, August 10). Exploring the Relationship between Food Additives and Cancer Risk. Rupa Health. https://www.rupahealth.com/post/exploring-the-relationship-between-food-additives-and-cancer-risk

Kresge, K. (2022, July 15). 7 Proven Ways to Get Seasonal Allergy Relief. Rupa Health. https://www.rupahealth.com/post/7-proven-ways-to-get-seasonal-allergy-relief

Li Y, Zhang Z, Paciulli M, Abbaspourrad A. Extraction of phycocyanin-A natural blue colorant from dried spirulina biomass: Influence of processing parameters and extraction techniques. J Food Sci. 2020;85(3):727-735. https://pubmed.ncbi.nlm.nih.gov/31999367/

Liu C, Zhan S, Tian Z, et al. Food Additives Associated with Gut Microbiota Alterations in Inflammatory Bowel Disease: Friends or Enemies?. Nutrients. 2022;14(15):3049. https://pubmed.ncbi.nlm.nih.gov/35893902/ 

Lombardelli C, Benucci I, Mazzocchi C, Esti M. Betalain Extracts from Beetroot as Food Colorants: Effect of Temperature and UV-Light on Storability. Plant Foods Hum Nutr. 2021;76(3):347-353. https://pubmed.ncbi.nlm.nih.gov/34351554/

Maholy, N. (2023, May 10). A Functional Medicine Immune Support Protocol. Rupa Health. https://www.rupahealth.com/post/a-functional-medicine-immune-support-protocol

Miller MD, Steinmaus C, Golub MS, et al. Potential impacts of synthetic food dyes on activity and attention in children: a human and animal evidence review. Environ Health. 2022;21(1):45. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052604/

Mindang ELN, Awounfack CF, Ndinteh DT, Krause RWM, Njamen D. Effects of Tartrazine on Some Sexual Maturation Parameters in Immature Female Wistar Rats. Int J Environ Res Public Health. 2022;19(16):10410. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408620/

Olas B, Białecki J, Urbańska K, Bryś M. The Effects of Natural and Synthetic Blue Dyes on Human Health: A Review of Current Knowledge and Therapeutic Perspectives. Adv Nutr. 2021;12(6):2301-2311. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634323/ 

Perara, H. (2024, April 11). The Ultimate Fiber Foods List: Boost Your Health with High-Fiber Choices. Rupa Health. https://www.rupahealth.com/post/ultimate-fiber-foods-list

Perara, H. (2024, May 31). What Are Nightshade Vegetables and Who Should Stop Eating Them? Rupa Health. https://www.rupahealth.com/post/what-are-nightshade-vegetables-and-who-should-stop-eating-them

Preston, J. (2023, February 23). Functional Medicine Treatment for Malabsorption Syndrome. Rupa Health. https://www.rupahealth.com/post/functional-medicine-treatment-for-malabsorption-syndrome

Preston, J. (2023, June 5). The Link Between Food Colors and Additives and Attention-Deficit-Hyperactivity Disorder and How to Test for Food Color and Additive Reactions. Rupa Health. https://www.rupahealth.com/post/the-link-between-food-colors-and-additives-and-attention-deficit-hyperactivity-disorder-adhd-how-to-test-for-food-color-and-additive-reactions

Sadighara P, Safta M, Limam I, et al. Association between food additives and prevalence of allergic reactions in children: a systematic review. Rev Environ Health. 2022;38(1):181-186. https://pubmed.ncbi.nlm.nih.gov/35106984/ 

Stanford, J. (2024, May 17). The Top 6 Anti-Inflammatory Spices to Incorporate Into Your Diet. Rupa Health. https://www.rupahealth.com/post/the-top-6-anti-inflammatory-spices-to-incorporate-into-your-diet

Stanford, J. (2024, April 18). What is Inflam-Aging? Rupa Health. https://www.rupahealth.com/post/what-is-inflam-aging

Sultana S, Rahman MM, Aovi FI, et al. Food Color Additives in Hazardous Consequences of Human Health: An Overview. Curr Top Med Chem. 2023;23(14):1380-1393. https://pubmed.ncbi.nlm.nih.gov/36650651/

Sweetnich, J. (2023, March 24). Vitamin A 101: Health Benefits, Testing, and Top Foods. Rupa Health. https://www.rupahealth.com/post/vitamin-a-101-health-benefits-testing-top-foods

United States Food and Drug Administration. (n.d.) Part I: The 1906 Food and Drug Act and It’s Enforcement. https://www.fda.gov/about-fda/changes-science-law-and-regulatory-authorities/part-i-1906-food-and-drugs-act-and-its-enforcement 

Zhang Q, Chumanevich AA, Nguyen I, et al. The synthetic food dye, Red 40, causes DNA damage, causes colonic inflammation, and impacts the microbiome in mice. Toxicol Rep. 2023;11:221-232. https://pubmed.ncbi.nlm.nih.gov/37719200/

Zhou X, Qiao K, Wu H, Zhang Y. The Impact of Food Additives on the Abundance and Composition of Gut Microbiota. Molecules. 2023;28(2):631. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864936/ 

Order from 30+ labs in 20 seconds (DUTCH, Mosaic, Genova & More!)
We make ordering quick and painless — and best of all, it's free for practitioners.

Latest Articles

View more on Nutrition
Subscribe to the Magazine for free
Subscribe for free to keep reading! If you are already subscribed, enter your email address to log back in.
Thanks for subscribing!
Oops! Something went wrong while submitting the form.
Are you a healthcare practitioner?
Thanks for subscribing!
Oops! Something went wrong while submitting the form.
Subscribe to the Magazine for free to keep reading!
Subscribe for free to keep reading, If you are already subscribed, enter your email address to log back in.
Thanks for subscribing!
Oops! Something went wrong while submitting the form.
Are you a healthcare practitioner?
Thanks for subscribing!
Oops! Something went wrong while submitting the form.
Trusted Source
Rupa Health
Medical Education Platform
Visit Source
Visit Source
American Cancer Society
Foundation for Cancer Research
Visit Source
Visit Source
National Library of Medicine
Government Authority
Visit Source
Visit Source
Journal of The American College of Radiology
Peer Reviewed Journal
Visit Source
Visit Source
National Cancer Institute
Government Authority
Visit Source
Visit Source
World Health Organization (WHO)
Government Authority
Visit Source
Visit Source
The Journal of Pediatrics
Peer Reviewed Journal
Visit Source
Visit Source
CDC
Government Authority
Visit Source
Visit Source
Office of Dietary Supplements
Government Authority
Visit Source
Visit Source
National Heart Lung and Blood Institute
Government Authority
Visit Source
Visit Source
National Institutes of Health
Government Authority
Visit Source
Visit Source
Clinical Infectious Diseases
Peer Reviewed Journal
Visit Source
Visit Source
Brain
Peer Reviewed Journal
Visit Source
Visit Source
The Journal of Rheumatology
Peer Reviewed Journal
Visit Source
Visit Source
Journal of the National Cancer Institute (JNCI)
Peer Reviewed Journal
Visit Source
Visit Source
Journal of Cardiovascular Magnetic Resonance
Peer Reviewed Journal
Visit Source
Visit Source
Hepatology
Peer Reviewed Journal
Visit Source
Visit Source
The American Journal of Clinical Nutrition
Peer Reviewed Journal
Visit Source
Visit Source
The Journal of Bone and Joint Surgery
Peer Reviewed Journal
Visit Source
Visit Source
Kidney International
Peer Reviewed Journal
Visit Source
Visit Source
The Journal of Allergy and Clinical Immunology
Peer Reviewed Journal
Visit Source
Visit Source
Annals of Surgery
Peer Reviewed Journal
Visit Source
Visit Source
Chest
Peer Reviewed Journal
Visit Source
Visit Source
The Journal of Neurology, Neurosurgery & Psychiatry
Peer Reviewed Journal
Visit Source
Visit Source
Blood
Peer Reviewed Journal
Visit Source
Visit Source
Gastroenterology
Peer Reviewed Journal
Visit Source
Visit Source
The American Journal of Respiratory and Critical Care Medicine
Peer Reviewed Journal
Visit Source
Visit Source
The American Journal of Psychiatry
Peer Reviewed Journal
Visit Source
Visit Source
Diabetes Care
Peer Reviewed Journal
Visit Source
Visit Source
The Journal of the American College of Cardiology (JACC)
Peer Reviewed Journal
Visit Source
Visit Source
The Journal of Clinical Oncology (JCO)
Peer Reviewed Journal
Visit Source
Visit Source
Journal of Clinical Investigation (JCI)
Peer Reviewed Journal
Visit Source
Visit Source
Circulation
Peer Reviewed Journal
Visit Source
Visit Source
JAMA Internal Medicine
Peer Reviewed Journal
Visit Source
Visit Source
PLOS Medicine
Peer Reviewed Journal
Visit Source
Visit Source
Annals of Internal Medicine
Peer Reviewed Journal
Visit Source
Visit Source
Nature Medicine
Peer Reviewed Journal
Visit Source
Visit Source
The BMJ (British Medical Journal)
Peer Reviewed Journal
Visit Source
Visit Source
The Lancet
Peer Reviewed Journal
Visit Source
Visit Source
Journal of the American Medical Association (JAMA)
Peer Reviewed Journal
Visit Source
Visit Source
Pubmed
Comprehensive biomedical database
Visit Source
Visit Source
Harvard
Educational/Medical Institution
Visit Source
Visit Source
Cleveland Clinic
Educational/Medical Institution
Visit Source
Visit Source
Mayo Clinic
Educational/Medical Institution
Visit Source
Visit Source
The New England Journal of Medicine (NEJM)
Peer Reviewed Journal
Visit Source
Visit Source
Johns Hopkins
Educational/Medical Institution
Visit Source
Visit Source

Hey Practitioners! Ready to become a world class gut health expert? Join Jeannie Gorman, MS, CCN, for a Free Live Class that dives into how popular diets impact the gut microbiome, the clinical dietary needs of your gut, biomarkers to test to analyze gut health, and gain a clear understanding of the Doctor’s Data GI360™ profile. Register here.