Mental Health
|
December 29, 2023

Saffron’s Natural Anti-Anxiety Properties and How To Consume More Of It

Written By
Brittney Bertagna RN
Medically Reviewed by
Dr. Jessica Christie ND, CNS
Updated On
January 14, 2025

Imagine feeling a sense of calm wash over you, your worries and fears easing away like snow in the sun. Sounds appealing, doesn't it? Well, what if I told you there's a natural option that may help support emotional well-being? 

Enter saffron, the golden spice with a rich history of traditional use. In this article, we'll explore the potential benefits of saffron and how you might incorporate more of this spice into your life. 

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Potential Benefits of Saffron

Anxiety is a common mental health condition characterized by excessive worry, fear, and apprehension. It can manifest as physical symptoms such as rapid heartbeat, shortness of breath, and sweating, as well as emotional symptoms like restlessness, irritability, and difficulty concentrating. Anxiety can significantly interfere with a person's daily life and overall well-being.

Therapeutic effects of saffron: anti-depression, antianxiety, anti-Alzheimer's, anti-Parkinson, anticancer, antidiabetic, anti-ischemic, anticonvulsant, & antipsychotic.

Saffron (Crocus sativus L.) is a plant that has a long history of traditional use. It is derived from the dried stigmas of the saffron crocus flower and is known for its distinct aroma, flavor, and vibrant yellow color. Saffron has been used for centuries in traditional practices to support various aspects of health, including mood and general well-being.

In recent years, there has been growing interest in the potential effects of saffron, particularly in the field of mental health. Several studies have investigated whether saffron supplementation can help with mood and emotional well-being. 

One study found that saffron supplementation had a positive effect on mood and emotional well-being when compared to placebo. The study also found that participants who received saffron extract reported improved social relationships. These findings suggest that saffron may support mood and emotional well-being.

Saffron's potential effectiveness in supporting mood and emotional well-being may be attributed to its constituents, such as crocin, crocetin, and safranal. These compounds have been reported to influence pathways related to neurotransmitters, immune regulation, inflammation, oxidative stress, and the hypothalamus-pituitary-adrenal axis, which are all implicated in mental health.

How Might Saffron Support Emotional Well-being?

Saffron, derived from the Crocus sativus plant, has been found to have potential benefits in supporting emotional well-being. Several studies have investigated the effects of saffron supplementation on mood and have reported positive results. 

The mechanisms through which saffron may support emotional well-being are not fully understood, but there are several potential explanations. Saffron contains compounds such as crocin, crocetin, and safranal, which have been shown to influence various neurobiological mechanisms implicated in mental health. 

These compounds may affect neurotransmitters, immune regulation, inflammation, oxidative stress, and the hypothalamus-pituitary-adrenal axis, all of which are involved in emotional well-being.

Furthermore, saffron has been found to increase the levels of crocetin in the body. Crocetin is a bioactive compound found in saffron that has been associated with mood support. Since mood and emotional well-being are often interconnected, the support of mood may contribute to overall emotional well-being.

How Much Saffron Should You Consider?

Although saffron supplementation has generally been well-tolerated, it is important to consider the duration and sample size of the studies conducted thus far. Most studies have been relatively short-term, and longer-term trials with larger sample sizes are needed to better assess the safety of saffron supplementation.

Ultimately, it is recommended to consult with a healthcare professional before starting saffron supplementation or any new treatment. They can provide personalized guidance based on your specific health condition, medications, and individual needs. 

Regarding the safe dose range for consuming saffron in supplement form, it is essential to consult with a healthcare professional before starting any new supplementation. The human trials that have examined specific health benefits of saffron have included doses ranging from 20 mg/d to 400 mg/d. 

However, fixed doses may not be optimal, and a dose-response relationship may exist. Therefore, it is encouraged for future studies to explore different saffron doses to determine the most effective and safe range.

Ways to Incorporate More Saffron Into Your Diet

There are several ways to incorporate more saffron into your diet, including supplementation. Saffron can be used as a spice in cooking, added to teas and beverages, or even used to infuse oils or other liquids with its unique flavor and color. 

Cooking: Saffron can be added to various dishes, such as rice, soups, stews, and sauces, to enhance their flavor and give them a vibrant yellow color. A pinch of saffron threads can be crushed and steeped in warm water or broth before adding it to the recipe.

Beverages: Saffron can be infused into hot water or herbal teas to create a soothing and aromatic drink. Simply add a few threads of saffron to a cup of hot water or tea and let it steep for a few minutes before enjoying.

Desserts: Saffron can be used to add a unique flavor and color to desserts like cakes, cookies, and puddings. It can be ground into a powder or soaked in a small amount of warm milk before being incorporated into the recipe.

Saffron Supplementation: If you prefer a more concentrated form of saffron, you can consider saffron supplements. These are available in capsule or tablet form and can be taken as directed by the manufacturer. It is important to choose a reputable brand and follow the recommended dosage.

Potential Side Effects of Adding Saffron To Your Diet

Saffron consumption has generally been reported to be safe and well-tolerated. However, like any substance, it may have potential side effects. The most commonly observed effects in saffron studies include changes in appetite, sedation, nausea, headache, and mood changes.

In studies comparing saffron with other options, saffron was associated with a lower frequency of certain effects such as sedation/drowsiness, headache, dry mouth, constipation, and changes in sexual function.

Who Should or Should Not Consider Saffron in Their Diet?

Saffron has been associated with potential benefits for mood and general mental health. Additionally, saffron may have a positive impact on sexual function in certain situations.

However, it is important to consult with a healthcare professional before starting saffron supplementation, especially if you have any underlying medical conditions or are taking medications. They can provide personalized advice based on your specific health situation and help determine if saffron is appropriate for you.

Individuals who are pregnant or breastfeeding should exercise caution when considering saffron supplementation. Although saffron has been used traditionally during pregnancy and lactation, there is limited research on its safety during these periods. It is advisable to consult with a healthcare professional before incorporating saffron into your diet or supplementation routine if you fall into these categories.

Furthermore, if you have any known allergies or sensitivities to saffron or related plants, it is recommended to avoid saffron consumption. Allergic reactions to saffron are rare but can occur in susceptible individuals.

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Key Takeaways When Considering Saffron

Saffron can be consumed by individuals in good health who do not have allergies or sensitivities to saffron. It may have potential benefits for mood, mental health, sexual function, and other health-related outcomes. However, it is always important to consult with a healthcare professional before starting any new treatment or supplementation, especially if you have underlying medical conditions, are pregnant or breastfeeding, or have known allergies or sensitivities to saffron. They can provide personalized advice based on your individual circumstances. 

The information in this article is designed for educational purposes only and is not intended to be a substitute for informed medical advice or care. This information should not be used to diagnose or treat any health problems or illnesses without consulting a doctor. Consult with a health care practitioner before relying on any information in this article or on this website.

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Bian, Y., Zhao, C., & Lee, S. M.-Y. (2020). Neuroprotective Potency of Saffron Against Neuropsychiatric Diseases, Neurodegenerative Diseases, and Other Brain Disorders: From Bench to Bedside. Frontiers in Pharmacology, 11. https://doi.org/10.3389/fphar.2020.579052

Brown, W. (2022). Saffron Research Analysis. Examine.com. https://examine.com/supplements/saffron/

Diorio, Dr. B. (2022, August 11). If You Experience Anxiety, GI Discomfort, or Irritability You May Have A Neurotransmitter Imbalance. Rupa Health. https://www.rupahealth.com/post/a-functional-medicine-approach-to-understanding-neurotransmitters-101

Hausenblas, H. A., Saha, D., Dubyak, P. J., & Anton, S. D. (2013). Saffron (Crocus sativus L.) and major depressive disorder: a meta-analysis of randomized clinical trials. Journal of Integrative Medicine, 11(6), 377–383. https://doi.org/10.3736/jintegrmed2013056

Mastering the Neurotransmitter-HPA Axis Connection for Enhanced Patient Outcomes. (n.d.). Rupa Health. Retrieved December 29, 2023, from https://www.rupahealth.com/live-classes/mastering-the-neurotransmitter-hpa-axis-connection-for-enhanced-patient-outcomes

Saffron: Uses, Side Effects, Interactions, Dosage, and Warning. (2019). Webmd.com. https://www.webmd.com/vitamins/ai/ingredientmono-844/saffron

Seyedeh Farzaneh Omidkhoda, & Hosseinzadeh, H. (2022). Saffron and its active ingredients against human disorders: A literature review on existing clinical evidence. PubMed, 25(8), 913–933. https://doi.org/10.22038/ijbms.2022.63378.13985

Teeter, L. A. (2023, April 27). Natural Remedies for Anxiety & Depression. Rupa Health. https://www.rupahealth.com/post/natural-remedies-for-anxiety-depression

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