Title
Subscribe to the Magazine for free
Subscribe for free to keep reading! If you are already subscribed, enter your email address to log back in.
Thanks for subscribing!
Oops! Something went wrong while submitting the form.
Are you a healthcare practitioner?
Thanks for subscribing!
Oops! Something went wrong while submitting the form.

Psoriasis and Related Conditions: The Connection to Diabetes, Obesity, and More

Written By

Why This Was Updated?

Our specialists regularly review advancements in health and wellness, ensuring our articles are updated with the newest information as it becomes accessible.
Medically Reviewed by
Dr.
Sarah Daglis
ND

Psoriasis is a chronic autoimmune skin condition marked by the accelerated production of skin cells, resulting in red, scaly patches. Driven by inflammation, it can impact more than just the skin.

This article explores the connections between psoriasis and related conditions like diabetes, obesity, and cardiovascular disease, highlighting its systemic nature.

Awareness of related health conditions (comorbidities) is essential for individuals with psoriasis. It allows for better overall health management and helps reduce risks associated with these interconnected conditions.

[signup]

Understanding Psoriasis as a Systemic Condition

Psoriasis is more than a skin condition; it involves systemic inflammation affecting various body parts, including the joints, heart, and other organs.

Chronic inflammation in psoriasis plays a role in the development of other health conditions, including cardiovascular disease, diabetes, and autoimmune disorders, highlighting its complexity as a systemic condition.

The Connection Between Psoriasis and Metabolic Syndrome

Metabolic syndrome encompasses a set of conditions that elevate the risk of diabetes, heart disease, and stroke. These include high blood pressure, elevated cholesterol levels, high blood sugar, and central obesity, marked by excess visceral fat around the body's midsection.

Psoriasis is linked to insulin resistance, where the body's cells become less responsive to insulin, increasing the risk of developing type 2 diabetes. This connection shows how psoriasis affects more than just the skin, impacting other critical bodily functions.

The relationship between psoriasis and obesity is significant. Excess weight, especially central obesity, can worsen psoriasis symptoms, creating a cycle where the condition may also contribute to further weight gain. This underscores the importance of weight management for individuals with psoriasis.

Additionally, those with psoriasis are at higher risk for high blood pressure and abnormal cholesterol levels, both key components of metabolic syndrome. These connections highlight the systemic nature of psoriasis and the need for comprehensive health management.

Psoriasis and Cardiovascular Disease

The chronic inflammation linked to psoriasis significantly elevates cardiovascular disease risk, including coronary artery disease and heart attacks. This inflammation affects the skin and contributes to the hardening and narrowing of arteries, making heart-related issues more likely in those with psoriasis.

There is also a notable link between psoriasis and an increased risk of stroke. The systemic inflammation that characterizes psoriasis can impact vascular health, leading to higher chances of stroke. This connection highlights the importance of monitoring vascular health in individuals with psoriasis.

Given these risks, regular cardiovascular screening is essential for those with psoriasis. Proactive heart health management, including lifestyle changes and suitable medical interventions, can help reduce these risks and enhance overall health outcomes.

Psoriasis and Diabetes

Individuals with psoriasis, especially those with severe cases, are at an increased risk of type 2 diabetes. The chronic inflammation associated with psoriasis can reduce insulin sensitivity, making it more difficult for the body to affect blood sugar levels.

This inflammation not only raises the risk of diabetes but also complicates blood sugar control in those already diagnosed.Insulin resistance, driven by inflammation, can lead to unstable blood sugar levels, making management more challenging.

Managing both psoriasis and diabetes requires a comprehensive approach. Key strategies involve a balanced diet, regular exercise, and strictly adhering to medication. These measures can enhance skin and blood sugar health, mitigating the effects of these interconnected conditions.

Psoriasis and Obesity

There is a bidirectional relationship between psoriasis and obesity; each condition can worsen the other. Obesity can exacerbate psoriasis symptoms due to increased inflammation, while psoriasis can contribute to weight gain, often due to reduced mobility or the effects of depression.

Both psoriasis and obesity share common inflammatory pathways, which intensify the severity of each condition. The chronic inflammation seen in psoriasis is similar to the inflammatory processes associated with obesity, creating a cycle that can make both conditions harder to manage.

Maintaining a healthy body weight is crucial for managing psoriasis symptoms and lowering the risk of related health issues. Weight management through diet, exercise, and lifestyle changes can help lower inflammation, improve skin health, and decrease the severity of psoriasis and obesity-related complications.

Other Related Conditions

Psoriasis is frequently associated with several other health conditions. Understanding these related conditions is crucial for managing the full spectrum of health impacts that psoriasis can have. Here are some of the key conditions commonly linked to psoriasis:

Psoriatic Arthritis

Psoriatic arthritis is a frequent comorbidity associated with psoriasis. It impacts the joints, leading to pain, stiffness, and swelling. This condition can significantly impact mobility and quality of life, often requiring specialized treatment to manage symptoms and prevent joint damage.

Depression and Anxiety

Individuals with psoriasis are at an increased risk of developing mental health conditions like depression and anxiety. The emotional impact of living with a chronic, visible condition can contribute to these issues, making mental health support an essential aspect of comprehensive care.

Non-Alcoholic Fatty Liver Disease (NAFLD)

There is a link between psoriasis and non-alcoholic fatty liver disease (NAFLD), particularly in those with metabolic syndrome or obesity. The chronic inflammation associated with psoriasis can contribute to liver inflammation and fat accumulation, increasing the risk of NAFLD.

Autoimmune Disorders

Psoriasis is also associated with other autoimmune conditions, such as Crohn's disease, lupus, and rheumatoid arthritis. The shared autoimmune nature of these conditions suggests that individuals with psoriasis may be more susceptible to developing other autoimmune disorders, further complicating their overall health.

Managing Psoriasis and Related Conditions

Effectively managing psoriasis necessitates a holistic approach that addresses both the skin condition and associated health issues. The following strategies are essential for effective management:

Integrated Care Approach

Effective management of psoriasis requires a holistic approach that involves collaboration between various healthcare specialists, such as dermatologists, endocrinologists, and cardiologists, to address both psoriasis and related health conditions comprehensively.

Lifestyle Modifications

Adopting a healthy lifestyle—through a balanced diet, regular exercise, effective stress management, and smoking cessation—can improve psoriasis symptoms and lower the risk of associated conditions such as cardiovascular disease and diabetes.

Medication

Certain medications, such as methotrexate, cyclosporine, and biologics like adalimumab, used to treat psoriasis, can also be beneficial in managing related conditions like psoriatic arthritis. Therefore, it is essential to coordinate treatment plans with a trusted healthcare provider to ensure optimal outcomes.

Regular Monitoring and Screening

Regular health screenings are vital for the early detection and management of comorbidities associated with psoriasis, allowing for timely interventions and better overall health management.

[signup]

Key Takeaways

  • Psoriasis is more than a skin condition; it is connected to various health issues, including diabetes, obesity, and cardiovascular disease. These connections emphasize the need for a comprehensive care approach that addresses psoriasis and its related conditions.
  • With proper care and management strategies, individuals with psoriasis can effectively manage their skin condition and reduce associated health risks. This includes treating skin symptoms, making lifestyle changes, managing medications, and undergoing regular health screenings.
  • Proactive health management and regular consultations with healthcare providers are essential. By staying informed and engaged in their care, individuals with psoriasis can lead healthier lives while managing both their skin and overall health.
The information provided is not intended to be a substitute for professional medical advice. Always consult with your doctor or other qualified healthcare provider before taking any dietary supplement or making any changes to your diet or exercise routine.
Learn More
No items found.

Lab Tests in This Article

No lab tests!

Achuff, J. (2024, March 19). Unveiling the shadow: How smoking casts a long-term impact on immune health. Rupa Health. https://www.rupahealth.com/post/unveiling-the-shadow-how-smoking-casts-a-long-term-impact-on-immune-health

Bertagna, B. (2024, January 10). The diabetes diet: Nutritional guidelines to help manage blood sugar. Rupa Health. https://www.rupahealth.com/post/the-diabetes-diet-nutritional-guidelines-to-help-manage-blood-sugar

Bhosle, M. J., Kulkarni, A., Feldman, S. R., & Balkrishnan, R. (2006). Quality of life in patients with psoriasis. Health and Quality of Life Outcomes, 4(1), 35. https://doi.org/10.1186/1477-7525-4-35

Christie, J. (2023, January 6). A functional medicine approach to obesity and weight management. Rupa Health. https://www.rupahealth.com/post/an-integrative-approach-to-obesity

Christie, J. (2024, May 17). How to spot the top warning signs of a stroke. Rupa Health. https://www.rupahealth.com/post/how-to-spot-the-top-warning-signs-of-a-stroke

Cloyd, J. (2023a, March 17). A functional medicine protocol for Crohn's disease. Rupa Health. https://www.rupahealth.com/post/a-functional-medicine-protocol-for-crohns-disease

Cloyd, J. (2023b, August 21). A root cause medicine protocol for patients with psoriasis: Comprehensive lab testing, therapeutic diet, and supplements. Rupa Health. https://www.rupahealth.com/post/a-root-cause-medicine-protocol-for-patients-with-psoriasis-comprehensive-lab-testing-therapeutic-diet-and-supplements

Cloyd, K. (2023, October 3). Functional medicine protocol for autoimmune diseases: Balancing the immune system. Rupa Health. https://www.rupahealth.com/post/functional-medicine-protocol-for-autoimmune-diseases-balancing-the-immune-system

DePorto, T. (2023, February 1). The gut's role in the development and treatment of psoriasis: A integrative medicine approach. Rupa Health. https://www.rupahealth.com/post/the-guts-role-in-the-development-and-treatment-of-psoriasis-a-integrative-medicine-approach

Ferreira, B. I. R. C., Abreu, J. L. P. D. C., Reis, J. P. G. D., & Figueiredo, A. M. D. C. (2016). Psoriasis and associated psychiatric disorders. The Journal of Clinical and Aesthetic Dermatology, 9(6), 36–43. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928455/

Garshick, M. S., Ward, N. L., Krueger, J. G., & Berger, J. S. (2021). Cardiovascular risk in patients with psoriasis: JACC review topic of the week. Journal of the American College of Cardiology, 77(13), 1670–1680. https://doi.org/10.1016/j.jacc.2021.02.009

Gelfand, J. M. (2016). Psoriasis, type 2 diabetes mellitus, and obesity. JAMA Dermatology, 152(7), 753. https://doi.org/10.1001/jamadermatol.2016.0670

Greenan, S. (2021, October 11). 7 early signs of insulin resistance. Rupa Health. https://www.rupahealth.com/post/what-is-insulin-resistance

Jensen, P., & Skov, L. (2016). Psoriasis and obesity. Dermatology, 232(6), 633–639. https://doi.org/10.1159/000455840

Khakham, C. (2023a, April 6). Understanding your risk of cardiovascular disease with functional medicine labs. Rupa Health. https://www.rupahealth.com/post/understanding-your-risk-of-cardiovascular-disease-with-functional-medicine-labs

Khakham, C. (2023b, June 8). Exploring the complexities of autoimmune diseases: Unraveling mechanisms, risk factors, and integrative approaches to testing, diagnosis, and treatment. Rupa Health. https://www.rupahealth.com/post/understanding-autoimmune-diseases-mechanisms-and-risk-factors

Khakham, C. (2023c, August 3). Top labs to run bi-annually on your high cholesterol patients. Rupa Health. https://www.rupahealth.com/post/top-labs-to-run-bi-annually-on-your-high-cholesterol-patients

Kresge, K. (2023, February 21). An integrative medicine approach to depression. Rupa Health. https://www.rupahealth.com/post/an-integrative-medicine-approach-to-depression

Lester, T. (2024, March 4). The role of lifestyle factors in autoimmune disease management. Rupa Health. https://www.rupahealth.com/post/the-role-of-lifestyle-factors-in-autoimmune-disease-management

Maholy, N. (2023a, February 17). A functional medicine approach to anxiety: Testing, nutrition, & supplements. Rupa Health. https://www.rupahealth.com/post/a-functional-medicine-approach-to-anxiety

Maholy, N. (2023b, May 26). Integrative nutrition approaches to managing blood sugar levels. Rupa Health. https://www.rupahealth.com/post/integrative-nutrition-approaches-to-managing-blood-sugar-levels

Maholy, N. (2023c, June 8). The impact of stress on autoimmune diseases: Exploring the potential of stress-reduction techniques. Rupa Health. https://www.rupahealth.com/post/the-impact-of-stress-on-autoimmune-diseases-and-the-potential-benefits-of-stress-reduction-techniques

National Psoriasis Foundation. (2021, January 14). About psoriasis. Www.psoriasis.org. https://www.psoriasis.org/about-psoriasis/

Ruan, Z., Lu, T., Chen, Y., Yuan, M., Yu, H., Liu, R., & Xie, X. (2022). Association between psoriasis and nonalcoholic fatty liver disease among outpatient US adults. JAMA Dermatology, 158(7), 745–753. https://doi.org/10.1001/jamadermatol.2022.1609

Sweetnich, J. (2023, April 25). Complementary and integrative medicine approaches to type 2 diabetes management. Rupa Health. https://www.rupahealth.com/post/complementary-and-integrative-medicine-approaches-to-type-2-diabetes-management

Teeter, L. A. (2023, April 4). Functional nutrition strategies for weight management and metabolic health. Rupa Health. https://www.rupahealth.com/post/functional-nutrition-strategies-for-weight-management-and-metabolic-health

Tiwari, V., & Brent, L. H. (2020). Psoriatic arthritis. PubMed; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK547710/

Weinberg, J. (2023, July 27). Integrative approaches to the testing and treatment of rheumatoid arthritis: A comprehensive review. Rupa Health. https://www.rupahealth.com/post/integrative-approaches-to-the-testing-and-treatment-of-rheumatoid-arthritis-a-comprehensive-review

Weinberg, J. L. (2023, June 1). If you're feeling fatigued and losing weight unexpectedly, ask your practitioner for these 6 lab tests. Rupa Health. https://www.rupahealth.com/post/a-functional-medicine-non-alcoholic-fatty-liver-disease-nafld-protocol-testing-nutrition-and-supplements

Wu, J. J., Kavanaugh, A., Lebwohl, M. G., Gniadecki, R., & Merola, J. F. (2022). Psoriasis and metabolic syndrome: Implications for the management and treatment of psoriasis. Journal of the European Academy of Dermatology and Venereology, 36(6), 797–806. https://doi.org/10.1111/jdv.18044

Yoshimura, H. (2023a, May 8). A functional medicine systemic lupus erythematosus (SLE) protocol: Testing, diagnosing, and treatment. Rupa Health. https://www.rupahealth.com/post/a-functional-medicine-systemic-lupus-erythematosus-sle-protocol-testing-diagnosing-and-treatment

Yoshimura, H. (2023b, November 7). The remarkable power of exercise on our health: A comprehensive overview. Rupa Health. https://www.rupahealth.com/post/the-remarkable-power-of-exercise-on-our-health-a-comprehensive-overview

Zhou, X., Chen, Y., Cui, L., Shi, Y., & Guo, C. (2022). Advances in the pathogenesis of psoriasis: From keratinocyte perspective. Cell Death & Disease, 13(1). https://doi.org/10.1038/s41419-022-04523-3

Subscribe to the Magazine for free to keep reading!
Subscribe for free to keep reading, If you are already subscribed, enter your email address to log back in.
Thanks for subscribing!
Oops! Something went wrong while submitting the form.
Are you a healthcare practitioner?
Thanks for subscribing!
Oops! Something went wrong while submitting the form.
See All Magazine Articles
Trusted Source
Rupa Health
Medical Education Platform
Visit Source
American Cancer Society
Foundation for Cancer Research
Visit Source
National Library of Medicine
Government Authority
Visit Source
Journal of The American College of Radiology
Peer Reviewed Journal
Visit Source
National Cancer Institute
Government Authority
Visit Source
World Health Organization (WHO)
Government Authority
Visit Source
The Journal of Pediatrics
Peer Reviewed Journal
Visit Source
CDC
Government Authority
Visit Source
Office of Dietary Supplements
Government Authority
Visit Source
National Heart Lung and Blood Institute
Government Authority
Visit Source
National Institutes of Health
Government Authority
Visit Source
Clinical Infectious Diseases
Peer Reviewed Journal
Visit Source
Brain
Peer Reviewed Journal
Visit Source
The Journal of Rheumatology
Peer Reviewed Journal
Visit Source
Journal of the National Cancer Institute (JNCI)
Peer Reviewed Journal
Visit Source
Journal of Cardiovascular Magnetic Resonance
Peer Reviewed Journal
Visit Source
Hepatology
Peer Reviewed Journal
Visit Source
The American Journal of Clinical Nutrition
Peer Reviewed Journal
Visit Source
The Journal of Bone and Joint Surgery
Peer Reviewed Journal
Visit Source
Kidney International
Peer Reviewed Journal
Visit Source
The Journal of Allergy and Clinical Immunology
Peer Reviewed Journal
Visit Source
Annals of Surgery
Peer Reviewed Journal
Visit Source
Chest
Peer Reviewed Journal
Visit Source
The Journal of Neurology, Neurosurgery & Psychiatry
Peer Reviewed Journal
Visit Source
Blood
Peer Reviewed Journal
Visit Source
Gastroenterology
Peer Reviewed Journal
Visit Source
The American Journal of Respiratory and Critical Care Medicine
Peer Reviewed Journal
Visit Source
The American Journal of Psychiatry
Peer Reviewed Journal
Visit Source
Diabetes Care
Peer Reviewed Journal
Visit Source
The Journal of the American College of Cardiology (JACC)
Peer Reviewed Journal
Visit Source
The Journal of Clinical Oncology (JCO)
Peer Reviewed Journal
Visit Source
Journal of Clinical Investigation (JCI)
Peer Reviewed Journal
Visit Source
Circulation
Peer Reviewed Journal
Visit Source
JAMA Internal Medicine
Peer Reviewed Journal
Visit Source
PLOS Medicine
Peer Reviewed Journal
Visit Source
Annals of Internal Medicine
Peer Reviewed Journal
Visit Source
Nature Medicine
Peer Reviewed Journal
Visit Source
The BMJ (British Medical Journal)
Peer Reviewed Journal
Visit Source
The Lancet
Peer Reviewed Journal
Visit Source
Journal of the American Medical Association (JAMA)
Peer Reviewed Journal
Visit Source
Pubmed
Comprehensive biomedical database
Visit Source
Harvard
Educational/Medical Institution
Visit Source
Cleveland Clinic
Educational/Medical Institution
Visit Source
Mayo Clinic
Educational/Medical Institution
Visit Source
The New England Journal of Medicine (NEJM)
Peer Reviewed Journal
Visit Source
Johns Hopkins
Educational/Medical Institution
Visit Source