GI Health
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February 19, 2024

Nutritional Interventions for Improved Gut Health in Post-Surgical Patients: Insights from Functional Medicine

Medically Reviewed by
Updated On
September 17, 2024

Sustaining optimal gut health is fundamental in preventing chronic disease and fostering overall well-being. Post-surgical patients, enduring stress, inflammation, and imbalances in the gut microbiome, face unique challenges in their recovery. Prioritizing digestive health becomes crucial for these individuals.

This article will discuss the significance of supporting gut health during the post-operative recovery phase. Holistic approaches focusing on functional medicine and nutrition effectively promote a balanced and resilient gut. Special attention will be given to nutritional interventions, emphasizing the pivotal role played by healthy bacteria in fortifying and maintaining optimal gastrointestinal health.

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The Importance of Gut Health Post-Surgery

The gut microbiome plays a vital role in maintaining the integrity of intestinal tissues, regulating the immune system, controlling inflammation, and supporting nutrient absorption. Surgeries, especially those involving the digestive system, can significantly impact gut health. Factors including stress, inflammation, antibiotic use, nutrient depletion, and reduced oxygen availability during surgery disrupt the microbiome, resulting in dysbiosis– an imbalance in good versus unfavorable microorganisms in the gut. If unaddressed, dysbiosis is associated with the development of numerous conditions.

Procedures like bariatric surgery or bowel resection present diverse challenges, often resulting in postoperative complications such as infections, nutrient malabsorption, and increased intestinal permeability (defects in the gut lining). These issues highlight the connection between gut health and the immune system's ability to heal and combat infections. The gut, home to many of the body’s immune cells, closely interacts with the microbiota. A well-balanced and diverse microbiome supports immune responses by competing with harmful invaders, producing antimicrobial substances, and maintaining an optimally acidic environment. Furthermore, it preserves the health of the gut lining by ensuring the integrity of tight junctions, prevents intestinal permeability, and reduces systemic inflammation.

Recognizing the beneficial relationship between a balanced microbiome and a healthy immune system highlights the critical nature of addressing post-surgical gut health. Understanding these dynamics is essential in developing comprehensive strategies to enhance recovery and prevent complications.

Common Gut Health Challenges After Surgery

Gut health challenges after surgery are prevalent and can significantly affect recovery and overall well-being. Here, we explore some common post-surgical issues and their repercussions.

Dysbiosis

Post-surgical dysbiosis often arises from standard practices such as the use of antibiotics and preoperative bowel cleansing, as well as the tissue damage that results from surgery. This imbalance in the gut microbiota can manifest as symptoms such as bloating, diarrhea, constipation, joint pain, skin issues, fatigue, and anxiety. If left unaddressed, dysbiosis may contribute significantly to the development of conditions like obesity, autoimmune disease, diabetes, infection, and cancer.

When the gut lacks a healthy balance of bacteria, it creates an environment where harmful microorganisms (“bad bugs”) can flourish, heightening the susceptibility to infections. This disruption can compromise the integrity of the gut barrier and weaken the immune system, causing delays in the recovery process.

Individuals experiencing dysbiosis before undergoing surgery may face even lengthier recovery periods. Pre-surgical dysbiosis is associated with extended recovery times, worsened dysbiosis after surgery, a higher incidence of postoperative diarrhea, and a significantly elevated risk of infection.

Constipation

Postoperative constipation, which is common in gastrointestinal surgeries, is a result of inflammation affecting gut motility, leading to postoperative ileus (POI). POI is a condition in which the intestines fail to move properly after surgery. In conditions like inflammatory bowel disease (IBD) or cancer, which may require surgical resection of the diseased intestine, constipation may result due to the development of POI.

According to a 2022 study that pooled data from 21 different research studies, supplementing with probiotics or synbiotics before and after surgery benefits gastrointestinal cancer patients. They experience faster recovery, have an earlier first bowel movement, start eating sooner, and have a lower risk of POI.

Constipation after surgery can cause significant discomfort, prolonged hospital stays, reduced appetite, and malnutrition, thereby delaying recovery.

Malabsorption

Surgical procedures, causing tissue damage and microbiome disruption, often result in malabsorption– compromised nutrient absorption. Signs of malabsorption may include diarrhea, the presence of fat in the stool, and unintentional weight loss. Common after bariatric surgery, malabsorption can lead to systemic issues such as fatigue, weakness, bone pain, poor wound healing, and overall prolonged recovery.

The Role of Functional Medicine Testing in Tailoring Nutritional Interventions

Functional medicine testing for gut health, such as stool analyses and nutrient assessments, is an effective means of tailoring nutrition post-surgery. These tests offer invaluable insights into specific gut health issues and nutrient deficiencies, guiding the development of individualized nutritional strategies.

Stool Analysis

Stool analysis is a comprehensive diagnostic tool that examines the digestive system’s functionality, providing information on microbiome content, the presence of harmful microorganisms, digestive efficiency, inflammation, and immune biomarkers.

Tests like the Comprehensive Stool Analysis from Mosaic Diagnostics and GI Effects Comprehensive Profile from Genova Diagnostics offer detailed insights, aiding in identifying dysbiosis, infections, and malnutrition.

GI-MAP from Diagnostic Solutions measures the DNA of the microbiota and potential pathogens (“bag bugs”) within a stool sample using a specialized technology. Zonulin is an optional addition to this test, a marker that provides insight into the health of tight junctions and plays a key role in gastrointestinal immunity.

Nutrient Assessments

Nutrient assessments are equally crucial for post-surgical patients; these evaluations play a key role in identifying specific nutrient deficiencies, which is essential for tailoring personalized treatment plans.

The NutrEval FMV test from Genova Diagnostics, which analyzes over 125 biomarkers and 40 nutrients through blood and urine samples, along with SpectraCell’s Micronutrient Test, which assesses 31 nutrients in the blood, serve to identify specific deficiencies and facilitate the customization of treatment plans.

Functional medicine testing provides a comprehensive understanding of the patient's unique needs, allowing practitioners to recommend targeted treatments, including nutritional guidance and supplements. This individualized approach ensures that post-surgery patients receive the specific support required for their recovery journey.

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Nutritional Strategies for Gut Health

Dietary strategies for gut healing and rebalancing the microbiota are important for supporting healthy gut tissues, immune resilience, efficient nutrient absorption, and accelerated recovery.

Research highlights the positive impact of probiotics and prebiotics on post-surgical patients. Prebiotics, non-digestible dietary fibers found in foods like garlic, onions, chicory root, Jerusalem artichokes, beans, and bananas, nourish and create a supportive environment for probiotics, such as Lactobacillus and Bifidobacterium strains. These beneficial microorganisms, accessible through supplements and functional foods, break down prebiotics into short-chain fatty acids (SCFAs), which promote intestinal cell health, optimize absorption, mitigate inflammation, and enhance post-surgery bowel function. Fermented foods like yogurt, kefir, sauerkraut, kimchi, tempeh, natto, miso, kombucha teas, and sourdough bread introduce probiotic bacteria, enriching the microbiota and reducing inflammation.

Beyond their prebiotic role, fiber-rich foods contribute to post-surgery recovery by enhancing motility, restoring and protecting gut tissues, reducing infection risk, and promoting overall gut function.

While incorporating these strategies is generally beneficial, caution is advised, especially after bowel surgery. It is recommended to seek guidance from a physician, as individual fiber needs may differ, and increased intake requires adequate water consumption to prevent dehydration.

In addition to fiber, probiotics, and prebiotics, specific nutrients may benefit gut health and recovery.

Glutamine

Glutamine, an amino acid sourced from poultry, fish, dairy products, and beans, serves as the primary fuel for small intestine cells. Supplementation has shown promise in improving protein levels and reducing inflammation. This contributes to enhanced recovery in post-surgical gastrointestinal cancer patients.

Zinc 

Zinc, particularly zinc carnosine, aids in healing damaged gut tissues, promoting healthy immune responses, and supporting enzyme function for optimal digestion and nutrient absorption. Dietary sources include meat, poultry, seafood, eggs, dairy, pumpkin seeds, and fortified cereals.

Omega-3 Fatty Acids

Abundant in fatty fish, walnuts, chia seeds, and flaxseed oil, omega-3 fatty acids exhibit anti-inflammatory effects and benefit the gut microbiome. They support microbial diversity, stimulate the growth of beneficial bacteria, reduce inflammation, regulate immune responses, counteract the effects of stress on the intestines, and elevate anti-inflammatory SCFA levels, including butyrate

Integrating these dietary strategies while considering individual needs contributes to a comprehensive approach to gut healing and microbiota rebalancing.

Implementing Nutritional Interventions

Navigating the intricacies of nutritional care post-surgery requires a comprehensive approach that considers common dietary restrictions and challenges. The key to successful recovery lies in tailoring nutritional support to individual needs and surgical outcomes. Here are some practical tips to seamlessly integrate nutritional care into the post-operative period:

1. Prioritize a Balanced Diet:

  • Consume a well-rounded diet rich in nutrients like protein, zinc, magnesium, and vitamin A before and after surgery to support healing
  • Opt for small, frequent meals to overcome challenges such as nausea, fatigue, and pain, ensuring consistent nutrient intake without overwhelming the system.

2. Eat Mindfully:

  • Practice mindful eating by chewing your food thoroughly and taking breaks between bites, facilitating the digestive process.
  • Control portion sizes to prevent overeating and discomfort, adhering to personalized guidelines provided by your healthcare provider.

3. Emphasize Protein:

  • Include protein-rich foods like chicken, beef, eggs, fish, lentils, nuts, tofu, and dairy in every meal or snack.
  • Consider supplemental protein shakes if solid foods pose difficulties. Aim for a daily intake of 65-75 grams to support tissue repair and muscle preservation.

4. Prioritize Hydration:

  • To promote optimal recovery, stay adequately hydrated by consuming water or unsweetened beverages throughout the day.

5. Supplement as Needed:

  • Discuss potential nutrient deficiencies with your healthcare provider and consider supplements like multivitamins or probiotics based on personalized stool or micronutrient testing.

6. Individualize the Approach:

  • Collaborate closely with your healthcare practitioner to develop a personalized nutrition plan aligned with your recovery needs.
  • For specific surgeries like bariatric procedures, follow a gradual progression from clear liquids to solid foods, emphasizing calorie control and nutrient balance.

7. Listen to Your Body:

  • Adapt your dietary choices based on individual tolerance levels and nutritional requirements.
  • Stay attuned to your body's signals and communicate openly with your healthcare provider for adjustments as needed.

8. Long-Term Monitoring:

  • Prioritize consistent long-term monitoring and support through regular check-ups and nutritional assessments.
  • Be attentive to your physical and mental well-being, seeking assistance when necessary for sustained success in your recovery journey.

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Nutritional interventions are crucial in supporting gut health and overall well-being in postoperative recovery. Understanding the impact of surgeries on the microbiota and the immune system, coupled with the complexity of these systems, emphasizes the need for personalized strategies. Functional medicine testing serves as an effective means for identifying imbalances and tailoring interventions to meet each patient’s unique needs. Prioritizing balanced diets, mindful eating, and targeted supplementation is imperative for optimizing post-surgical outcomes. Healthcare providers are encouraged to adopt functional medicine principles in postoperative care to best support patients' recovery journey.

Maintaining a healthy gut is important for overall well-being. After surgery, patients may experience stress, inflammation, and changes in the gut microbiome, which can affect their recovery. Focusing on digestive health can be beneficial for these individuals.

This article will explore ways to support gut health during recovery after surgery. Holistic approaches, including functional medicine and nutrition, can help promote a balanced and resilient gut. We will look at nutritional interventions and the role of healthy bacteria in supporting gastrointestinal health.

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The Importance of Gut Health Post-Surgery

The gut microbiome is important for maintaining intestinal tissues, supporting the immune system, managing inflammation, and aiding nutrient absorption. Surgeries, especially those involving the digestive system, can affect gut health. Factors like stress, inflammation, antibiotic use, nutrient depletion, and reduced oxygen during surgery can disrupt the microbiome, leading to dysbiosis– an imbalance in gut microorganisms. If not addressed, dysbiosis may be linked to various health issues.

Procedures like bariatric surgery or bowel resection can present challenges, sometimes leading to postoperative complications such as infections, nutrient malabsorption, and increased intestinal permeability (changes in the gut lining). These issues highlight the connection between gut health and the immune system's ability to heal and manage infections. The gut, home to many immune cells, interacts with the microbiota. A balanced and diverse microbiome can support immune responses by competing with harmful invaders, producing substances that help manage microbes, and maintaining a healthy environment. It also helps preserve the gut lining by supporting tight junctions, may help prevent intestinal permeability, and reduce systemic inflammation.

Recognizing the beneficial relationship between a balanced microbiome and a healthy immune system highlights the importance of addressing post-surgical gut health. Understanding these dynamics can help in developing strategies to enhance recovery and manage complications.

Common Gut Health Challenges After Surgery

Gut health challenges after surgery are common and can affect recovery and overall well-being. Here, we explore some common post-surgical issues and their effects.

Dysbiosis

Post-surgical dysbiosis can result from practices such as the use of antibiotics and preoperative bowel cleansing, as well as tissue changes from surgery. This imbalance in the gut microbiota can lead to symptoms such as bloating, diarrhea, constipation, joint pain, skin issues, fatigue, and anxiety. If not addressed, dysbiosis may contribute to conditions like obesity, autoimmune disease, diabetes, infection, and cancer.

When the gut lacks a healthy balance of bacteria, it may create an environment where harmful microorganisms can grow, increasing the risk of infections. This disruption can affect the gut barrier and immune system, potentially delaying recovery.

Individuals experiencing dysbiosis before surgery may face longer recovery periods. Pre-surgical dysbiosis is linked to extended recovery times, worsened dysbiosis after surgery, a higher chance of postoperative diarrhea, and an increased risk of infection.

Constipation

Postoperative constipation, common in gastrointestinal surgeries, can result from inflammation affecting gut motility, leading to postoperative ileus (POI). POI is a condition where the intestines do not move properly after surgery. In conditions like inflammatory bowel disease (IBD) or cancer, which may require surgical resection of the intestine, constipation may occur due to POI.

According to a 2022 study that reviewed data from 21 studies, using probiotics or synbiotics before and after surgery may benefit gastrointestinal cancer patients. They may experience faster recovery, have an earlier first bowel movement, start eating sooner, and have a lower risk of POI.

Constipation after surgery can cause discomfort, longer hospital stays, reduced appetite, and malnutrition, potentially delaying recovery.

Malabsorption

Surgical procedures, which can affect tissues and the microbiome, may lead to malabsorption– affecting nutrient absorption. Signs of malabsorption may include diarrhea, fat in the stool, and unintentional weight loss. Common after bariatric surgery, malabsorption can lead to systemic issues such as fatigue, weakness, bone pain, poor wound healing, and longer recovery.

The Role of Functional Medicine Testing in Tailoring Nutritional Interventions

Functional medicine testing for gut health, such as stool analyses and nutrient assessments, can help tailor nutrition post-surgery. These tests provide insights into specific gut health issues and nutrient deficiencies, guiding the development of personalized nutritional strategies.

Stool Analysis

Stool analysis is a tool that examines the digestive system’s functionality, providing information on microbiome content, the presence of microorganisms, digestive efficiency, inflammation, and immune markers.

Tests like the Comprehensive Stool Analysis from Mosaic Diagnostics and GI Effects Comprehensive Profile from Genova Diagnostics offer insights, aiding in identifying dysbiosis, infections, and malnutrition.

GI-MAP from Diagnostic Solutions measures the DNA of the microbiota and potential pathogens within a stool sample using specialized technology. Zonulin is an optional addition to this test, a marker that provides insight into the health of tight junctions and plays a role in gastrointestinal immunity.

Nutrient Assessments

Nutrient assessments are important for post-surgical patients; these evaluations help identify specific nutrient deficiencies, which is essential for creating personalized treatment plans.

The NutrEval FMV test from Genova Diagnostics, which analyzes over 125 biomarkers and 40 nutrients through blood and urine samples, along with SpectraCell’s Micronutrient Test, which assesses 31 nutrients in the blood, help identify specific deficiencies and facilitate the customization of treatment plans.

Functional medicine testing provides a comprehensive understanding of the patient's needs, allowing practitioners to recommend targeted treatments, including nutritional guidance and supplements. This personalized approach helps ensure that post-surgery patients receive the support needed for their recovery journey.

[signup]

Nutritional Strategies for Gut Health

Dietary strategies for gut health and rebalancing the microbiota are important for supporting healthy gut tissues, immune resilience, nutrient absorption, and recovery.

Research suggests that probiotics and prebiotics may benefit post-surgical patients. Prebiotics, non-digestible dietary fibers found in foods like garlic, onions, chicory root, Jerusalem artichokes, beans, and bananas, nourish and create a supportive environment for probiotics, such as Lactobacillus and Bifidobacterium strains. These beneficial microorganisms, available through supplements and functional foods, break down prebiotics into short-chain fatty acids (SCFAs), which support intestinal cell health, optimize absorption, manage inflammation, and enhance bowel function after surgery. Fermented foods like yogurt, kefir, sauerkraut, kimchi, tempeh, natto, miso, kombucha teas, and sourdough bread introduce probiotic bacteria, supporting the microbiota and managing inflammation.

Beyond their prebiotic role, fiber-rich foods contribute to post-surgery recovery by enhancing motility, supporting gut tissues, reducing infection risk, and promoting overall gut function.

While incorporating these strategies is generally beneficial, caution is advised, especially after bowel surgery. It is recommended to seek guidance from a physician, as individual fiber needs may differ, and increased intake requires adequate water consumption to prevent dehydration.

In addition to fiber, probiotics, and prebiotics, specific nutrients may support gut health and recovery.

Glutamine

Glutamine, an amino acid found in poultry, fish, dairy products, and beans, serves as a primary fuel for small intestine cells. Supplementation has shown potential in supporting protein levels and managing inflammation, which may aid recovery in post-surgical gastrointestinal cancer patients.

Zinc 

Zinc, particularly zinc carnosine, may help in supporting gut tissues, promoting healthy immune responses, and aiding enzyme function for digestion and nutrient absorption. Dietary sources include meat, poultry, seafood, eggs, dairy, pumpkin seeds, and fortified cereals.

Omega-3 Fatty Acids

Found in fatty fish, walnuts, chia seeds, and flaxseed oil, omega-3 fatty acids may have anti-inflammatory effects and support the gut microbiome. They may help support microbial diversity, stimulate the growth of beneficial bacteria, manage inflammation, regulate immune responses, counteract stress effects on the intestines, and elevate anti-inflammatory SCFA levels, including butyrate

Integrating these dietary strategies while considering individual needs contributes to a comprehensive approach to gut health and microbiota balance.

Implementing Nutritional Interventions

Navigating nutritional care post-surgery requires a comprehensive approach that considers dietary restrictions and challenges. Successful recovery involves tailoring nutritional support to individual needs and surgical outcomes. Here are some practical tips to integrate nutritional care into the post-operative period:

1. Prioritize a Balanced Diet:

  • Consume a well-rounded diet rich in nutrients like protein, zinc, magnesium, and vitamin A before and after surgery to support healing
  • Opt for small, frequent meals to manage challenges such as nausea, fatigue, and pain, ensuring consistent nutrient intake without overwhelming the system.

2. Eat Mindfully:

  • Practice mindful eating by chewing your food thoroughly and taking breaks between bites, aiding the digestive process.
  • Control portion sizes to prevent overeating and discomfort, following personalized guidelines from your healthcare provider.

3. Emphasize Protein:

  • Include protein-rich foods like chicken, beef, eggs, fish, lentils, nuts, tofu, and dairy in every meal or snack.
  • Consider supplemental protein shakes if solid foods are challenging. Aim for a daily intake of 65-75 grams to support tissue repair and muscle preservation.

4. Prioritize Hydration:

  • To support recovery, stay adequately hydrated by consuming water or unsweetened beverages throughout the day.

5. Supplement as Needed:

  • Discuss potential nutrient deficiencies with your healthcare provider and consider supplements like multivitamins or probiotics based on personalized stool or micronutrient testing.

6. Individualize the Approach:

  • Collaborate closely with your healthcare practitioner to develop a personalized nutrition plan aligned with your recovery needs.
  • For specific surgeries like bariatric procedures, follow a gradual progression from clear liquids to solid foods, emphasizing calorie control and nutrient balance.

7. Listen to Your Body:

  • Adapt your dietary choices based on individual tolerance levels and nutritional requirements.
  • Stay attuned to your body's signals and communicate openly with your healthcare provider for adjustments as needed.

8. Long-Term Monitoring:

  • Prioritize consistent long-term monitoring and support through regular check-ups and nutritional assessments.
  • Be attentive to your physical and mental well-being, seeking assistance when necessary for sustained success in your recovery journey.

[signup]

Nutritional interventions are important in supporting gut health and overall well-being in postoperative recovery. Understanding the impact of surgeries on the microbiota and the immune system, along with the complexity of these systems, highlights the need for personalized strategies. Functional medicine testing can help identify imbalances and tailor interventions to meet each patient’s needs. Prioritizing balanced diets, mindful eating, and targeted supplementation is key for optimizing post-surgical outcomes. Healthcare providers are encouraged to adopt functional medicine principles in postoperative care to best support patients' recovery journey.

The information provided is not intended to be a substitute for professional medical advice. Always consult with your doctor or other qualified healthcare provider before taking any dietary supplement or making any changes to your diet or exercise routine.

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Lab Tests in This Article

Agnes, A., Puccioni, C., D'Ugo, D., Gasbarrini, A., Biondi, A., & Persiani, R. (2021). The gut microbiota and colorectal surgery outcomes: facts or hype? A narrative review. BMC surgery, 21(1), 83. https://doi.org/10.1186/s12893-021-01087-5

Bertagna, B. (2024, January 9). The Science Behind Mindful Eating: How It Impacts Digestion and Overall Health. Rupa Health. https://www.rupahealth.com/post/the-science-behind-mindful-eating-how-it-impacts-digestion-and-overall-health

Buchanan, L., & Tuma, F. (2023, July 31). Postoperative Ileus. In StatPearls [Internet]. StatPearls Publishing. Retrieved January 1, 2024, from https://www.ncbi.nlm.nih.gov/books/NBK560780/

Chapmon, K. (2021, December 6). A Functional Medicine Approach to Bariatric Surgery. Rupa Health. https://www.rupahealth.com/post/a-functional-medicine-approach-to-bariatric-surgery

Cloyd, J. (2022, December 8). 3 Natural Treatments For Inflammatory Bowel Disease. Rupa Health. https://www.rupahealth.com/post/inflammatory-bowel-disease-ibd-treatments-for-flares-and-remission

Cloyd, J. (2023a, February 24). Micronutrient Testing 101: A Complete Guide To The Top 4 Micronutrient Test. Rupa Health. https://www.rupahealth.com/post/micronutrient-testing-101-a-complete-guide-to-the-top-4-micronutrient-test

Cloyd, J. (2023b, March 6). The Microbiome-Joint Axis: Exploring the Gut’s Influence on Joint Pain. Rupa Health. https://www.rupahealth.com/post/the-guts-role-in-joint-inflammation

Cloyd, J. (2023c, March 7). An integrative medicine approach to fatigue. Rupa Health. https://www.rupahealth.com/post/an-integrative-medicine-approach-to-fatigue

Cloyd, J. (2023d, March 8). Butyrate 101: Everything You Need to Know About This Short Chain Fatty Acid. Rupa Health. https://www.rupahealth.com/post/butyrate-101-everything-you-need-to-know-about-this-short-chain-fatty-acid

Cloyd, J. (2023e, March 22). 10 Differential Diagnoses for Your Constipation Patients. Rupa Health. https://www.rupahealth.com/post/10-differential-diagnoses-for-your-constipation-patients

Cloyd, J. (2023f, April 11). A Functional Medicine Post-Operative Protocol. Rupa Health. https://www.rupahealth.com/post/a-functional-medicine-post-operative-protocol

Cloyd, J. (2023g, April 19). What’s the Difference Between Prebiotics vs. Probiotics vs. Postbiotics? Rupa Health. https://www.rupahealth.com/post/whats-the-difference-between-prebiotics-vs-probiotics-vs-postbiotics

Cloyd, J. (2023h, April 20). Antibiotics 101: What You Need To Know. Rupa Health. https://www.rupahealth.com/post/antibiotics-101-what-you-need-to-know

Cloyd, J. (2023i, April 28). How to Heal Your Gut Naturally With Functional Nutrition. Rupa Health. https://www.rupahealth.com/post/how-to-heal-your-gut-naturally-with-functional-nutrition

Cloyd, J. (2023j, May 19). The Impact of The Gut Microbiome on Autoimmune Diseases. Rupa Health. https://www.rupahealth.com/post/the-impact-of-the-gut-microbiome-on-autoimmune-diseases

Cloyd, J. (2023k, July 3). The Importance of Comprehensive Stool Testing in Functional Medicine. Rupa Health. https://www.rupahealth.com/post/the-importance-of-comprehensive-stool-testing-in-functional-medicine

Cloyd, J. (2023l, November 16). How A Leaky Gut Could Be Contributing to Your Inflammation. Rupa Health. https://www.rupahealth.com/post/how-a-leaky-gut-could-be-contributing-to-your-inflammation

Cloyd, J. (2023m, November 29). The Hidden Impact of Our Gut: How Intestinal Permeability Influences a Range of Diseases. Rupa Health. https://www.rupahealth.com/post/the-hidden-impact-of-our-gut-how-intestinal-permeability-influences-a-range-of-diseases

Cloyd, J. (2024a, January 8). The Science of Hydration: How Water Intake Affects Overall Health. Rupa Health. https://www.rupahealth.com/post/the-science-of-hydration-how-water-intake-affects-overall-health

Cloyd, J. (2024b, January 25). What is the Gut Microbiome? Rupa Health. https://www.google.com/url?q=https://www.rupahealth.com/post/what-is-the-gut-microbiome&sa=D&source=docs&ust=1707340686427316&usg=AOvVaw2qifK0g3lysN7NMFzxnhlc

Cloyd, K. (2023a, October 4). Inflammation and Gut Health: Understanding the Impact on Overall Well-Being. Rupa Health. https://www.rupahealth.com/post/inflammation-and-gut-health-understanding-the-impact-on-overall-well-being

Cloyd, K. (2023b, November 17). Gut Microbiome Diversity: The Cornerstone of Immune Resilience. Rupa Health. https://www.rupahealth.com/post/gut-microbiome-diversity-the-cornerstone-of-immune-resilience

Cloyd, K. (2024a, January 17). Understanding Nutritional Deficiencies: When to Utilize Micronutrient Testing. Rupa Health. https://www.rupahealth.com/post/understanding-nutritional-deficiencies-when-to-utilize-micronutrient-testing

Cloyd, K. (2024b, January 22). Functional Medicine for Managing Gut Health in Patients with Diabetes. Rupa Health. https://www.rupahealth.com/post/functional-medicine-for-managing-gut-health-in-patients-with-diabetes

Comprehensive Stool Analysis by Mosaic Diagnostics (formerly Great Plains). (n.d.). Rupa Health. Retrieved February 7, 2024, from https://www.rupahealth.com/lab-tests/mosaic-diagnostics-comprehensive-stool-analysis

Dawoodbhoy, F. M., Patel, B. K., Patel, K., Bhatia, M., Lee, C. N., & Moochhala, S. M. (2021). Gut Microbiota Dysbiosis as a Target for Improved Post-Surgical Outcomes and Improved Patient Care: A Review of Current Literature. SHOCK, 55(4), 441-454. https://doi.org/10.1097/SHK.0000000000001654

DeCesaris, L. (2022, June 6). What Is Gut Dysbiosis? 7 Signs To Watch For. Rupa Health. https://www.rupahealth.com/post/how-your-gut-bacteria-affects-your-overall-health

Fu, Y., Wang, Y., Gao, H., Li, D., Jiang, R., Ge, L., Tong, C., & Xu, K. (2021). Associations among Dietary Omega-3 Polyunsaturated Fatty Acids, the Gut Microbiota, and Intestinal Immunity. Mediators of inflammation, 2021, 8879227. https://doi.org/10.1155/2021/8879227

Ganipisetti, V. M., & Naha, S. (2023, May 19). Bariatric Surgery Malnutrition Complications. In StatPearls [Internet]. StatPearls Publishing. Retrieved January 2024, from https://www.ncbi.nlm.nih.gov/books/NBK592383/

García-Montero, C., Fraile-Martínez, O., Gómez-Lahoz, A. M., Pekarek, L., Castellanos, A. J., Noguerales-Fraguas, F., Coca, S., Guijarro, L. G., García-Honduvilla, N., Asúnsolo, A., Sanchez-Trujillo, L., Lahera, G., Bujan, J., Monserrat, J., Álvarez-Mon, M., Álvarez-Mon, M. A., & Ortega, M. A. (2021). Nutritional Components in Western Diet Versus Mediterranean Diet at the Gut Microbiota-Immune System Interplay. Implications for Health and Disease. Nutrients, 13(2), 699. https://doi.org/10.3390/nu13020699

GI Effects® Comprehensive Profile - 1 day by Genova Diagnostics. (n.d.). Rupa Health. Retrieved February 7, 2024, from https://www.rupahealth.com/lab-tests/genova-gi-effects-comprehensive-profile-1-day

GI-MAP by Diagnostic Solutions. (n.d.). Rupa Health. https://www.rupahealth.com/lab-tests/diagnostic-solutions-gi-map

Greenan, S. (2021, December 8). 5 Probiotic-Rich Foods To Eat Instead Of Taking Supplements. Rupa Health. https://www.rupahealth.com/post/the-different-types-of-probiotics-health-benefits

Hills, R. D., Jr, Pontefract, B. A., Mishcon, H. R., Black, C. A., Sutton, S. C., & Theberge, C. R. (2019). Gut Microbiome: Profound Implications for Diet and Disease. Nutrients, 11(7), 1613. https://doi.org/10.3390/nu11071613

Ioannidis, O., Chatzakis, C., Tirta, M., Anestiadou, E., Zapsalis, K., Symeonidis, S., Bitsianis, S., Kotidis, E., Pramateftakis, M. G., Mantzoros, I., & Angelopoulos, S. (2023). The Efficacy of Probiotics, Prebiotics, and Synbiotics in Patients Who Have Undergone Abdominal Operation, in Terms of Bowel Function Post-Operatively: A Network Meta-Analysis. Journal of clinical medicine, 12(12), 4150. https://doi.org/10.3390/jcm12124150

Ioniță-Mîndrican, C. B., Ziani, K., Mititelu, M., Oprea, E., Neacșu, S. M., Moroșan, E., Dumitrescu, D. E., Roșca, A. C., Drăgănescu, D., & Negrei, C. (2022). Therapeutic Benefits and Dietary Restrictions of Fiber Intake: A State of the Art Review. Nutrients, 14(13), 2641. https://doi.org/10.3390/nu14132641

Jeppsson B. (2018). Gut microbiota and surgical disease. Hepatobiliary surgery and nutrition, 7(1), 32–33. https://doi.org/10.21037/hbsn.2017.11.03

Ji, W., Chandoo, A., Guo, X., You, T., Shao, Z., Zheng, K., Wang, J., Bi, J., Smith, F. G., Tucker, O. N., & Shen, X. (2018). Enhanced recovery after surgery decreases intestinal recovery time and pain intensity in patients undergoing curative gastrectomy. Cancer management and research, 10, 3513–3520. https://doi.org/10.2147/CMAR.S168909

Jin, Y., Geng, R., Liu, Y., Liu, L., Jin, X., Zhao, F., Feng, J., & Wei, Y. (2020). Prediction of Postoperative Ileus in Patients With Colorectal Cancer by Preoperative Gut Microbiota. Frontiers in oncology, 10, 526009. https://doi.org/10.3389/fonc.2020.526009

Khakham, C. (2023a, May 15). Boosting Your Patient’s Immunity Through Gut Health: Testing, Nutrition and Supplements. Rupa Health. https://www.rupahealth.com/post/the-gut-microbiome-and-immunity-how-integrative-approaches-can-boost-immune-function

Khakham, C. (2023b, May 16). Natural Anti-Inflammatory Agents for Gut Health: An Evidence-Based Review. Rupa Health. https://www.rupahealth.com/post/natural-anti-inflammatory-agents-for-gut-health-an-evidence-based-review

Liu, Y., He, W., Yang, J. et al. The effects of preoperative intestinal dysbacteriosis on postoperative recovery in colorectal cancer surgery: a prospective cohort study. BMC Gastroenterol 21, 446 (2021). https://doi.org/10.1186/s12876-021-02035-6

LoBisco, S. (2022a, September 16). How Food Affects Your Mood Through The Gut-Brain Axis. Rupa Health. https://www.rupahealth.com/post/gut-brain-axis

LoBisco, S. (2022b, December 14). How To Build A Healthy Microbiome From Birth. Rupa Health. https://www.rupahealth.com/post/building-a-healthy-microbiome-from-birth

Mazzotta, E., Villalobos-Hernandez, E. C., Fiorda-Diaz, J., Harzman, A., & Christofi, F. L. (2020). Postoperative Ileus and Postoperative Gastrointestinal Tract Dysfunction: Pathogenic Mechanisms and Novel Treatment Strategies Beyond Colorectal Enhanced Recovery After Surgery Protocols. Frontiers in pharmacology, 11, 583422. https://doi.org/10.3389/fphar.2020.583422

McNally, L. (2023, November 27). The Association Between the Microbiome and Cancer. Rupa Health. https://www.rupahealth.com/post/the-association-between-the-microbiome-and-cancer

Micronutrient Test by SpectraCell Laboratories. (n.d.). Rupa Health. https://www.rupahealth.com/lab-tests/spectracell-micronutrient-test

Neibling, K. (2023a, March 24). Why Functional Medicine Practitioners Focus on Gut Health. Rupa Health. https://www.rupahealth.com/post/why-functional-medicine-practitioners-focus-on-gut-health

Neibling, K. (2023b, March 28). What is Functional Medicine Nutrition?: The Link Between Diet and Health. Rupa Health. https://www.rupahealth.com/post/what-is-functional-medicine-nutrition-the-link-between-diet-and-health

NutrEval® FMV by Genova Diagnostics. (n.d.). Rupa Health. Retrieved February 7, 2024, from https://www.rupahealth.com/lab-tests/genova-nutreval-fmv

Nutrition To Help Heal Your Wounds After Surgery | Memorial Sloan Kettering Cancer Center. (2022, November 15). Www.mskcc.org. https://www.mskcc.org/cancer-care/patient-education/nutrition-help-heal-your-wounds-after-surgery

Piccioni, A., Covino, M., Candelli, M., Ojetti, V., Capacci, A., Gasbarrini, A., Franceschi, F., & Merra, G. (2023). How Do Diet Patterns, Single Foods, Prebiotics and Probiotics Impact Gut Microbiota? Microbiology Research, 14(1), 390-408. https://doi.org/10.3390/microbiolres14010030

Preston , J. (2023, February 23). Functional Medicine Treatment for Malabsorption Syndrome. Rupa Health. https://www.rupahealth.com/post/functional-medicine-treatment-for-malabsorption-syndrome

Sweetnich, J. (2023, February 21). Top Gut Healing Supplements Used By Integrative Medicine Practitioners. Rupa Health. https://www.rupahealth.com/post/top-gut-healing-supplements-used-by-integrative-medicine-practitioners

Tang, G., Huang, W., Tao, J., & Wei, Z. (2022). Prophylactic effects of probiotics or synbiotics on postoperative ileus after gastrointestinal cancer surgery: A meta-analysis of randomized controlled trials. PloS one, 17(3), e0264759. https://doi.org/10.1371/journal.pone.0264759

UCSF Health. (2019, March 14). Dietary Guidelines After Bariatric Surgery. Ucsfhealth.org; UCSF Health. https://www.ucsfhealth.org/education/dietary-guidelines-after-bariatric-surgery

Weinberg, J. (2022, December 19). How Short Chain Fatty Acids Affects Our Mood, Digestion, and Metabolism. Rupa Health. https://www.rupahealth.com/post/how-short-chain-fatty-acids-affects-our-mood-digestion-and-metabolism

Weinberg, J. (2023, October 27). The Relationship Between Gut Health and Weight Balance. Rupa Health. https://www.rupahealth.com/post/the-relationship-between-gut-health-and-weight-balance

Weinberg, J. (2024a, January 5). Navigating Nutrient Absorption: Functional Medicine for Optimal Digestion. Rupa Health. https://www.rupahealth.com/post/navigating-nutrient-absorption-functional-medicine-for-optimal-digestion

Weinberg, J. (2024b, January 18). Chronic Constipation and Gut Motility: Functional Medicine Interventions and Solutions. Rupa Health. https://www.rupahealth.com/post/chronic-constipation-and-gut-motility-functional-medicine-interventions-and-solutions

Wiertsema, S. P., van Bergenhenegouwen, J., Garssen, J., & Knippels, L. M. J. (2021). The Interplay between the Gut Microbiome and the Immune System in the Context of Infectious Diseases throughout Life and the Role of Nutrition in Optimizing Treatment Strategies. Nutrients, 13(3), 886. https://doi.org/10.3390/nu13030886

Wood Heickman, L. K., DeBoer, M. D., & Fasano, A. (2020). Zonulin as a potential putative biomarker of risk for shared type 1 diabetes and celiac disease autoimmunity. Diabetes/metabolism research and reviews, 36(5), e3309. https://doi.org/10.1002/dmrr.3309

Xiong, K., Li, G., Zhang, Y., Bao, T., Li, P., Yang, X., & Chen, J. (2023). Effects of glutamine on plasma protein and inflammation in postoperative patients with colorectal cancer: a meta-analysis of randomized controlled trials. International journal of colorectal disease, 38(1), 212. https://doi.org/10.1007/s00384-023-04504-8

Yoshimura, H. (2023a, June 7). The Gut Microbiomes Role in Skin Health. Rupa Health. https://www.rupahealth.com/post/the-gut-microbiomes-role-in-skin-health

Yoshimura, H. (2023b, October 23). Are Supplements Really Necessary?: Pros, Cons, and How Testing Can Help. Rupa Health. https://www.rupahealth.com/post/are-supplements-really-necessary-pros-cons-and-how-testing-can-help

Yoshimura, H. (2023c, November 2). From Zinc to Magnesium: Micronutrients that Supercharge Gut Healing. Rupa Health. https://www.rupahealth.com/post/from-zinc-to-magnesium-micronutrients-that-supercharge-gut-healing

Yoshimura, H. (2024, January 18). Optimizing Gut Health in Bariatric Surgery Patients: Post-Operative Functional Medicine Care. Rupa Health. https://www.rupahealth.com/post/optimizing-gut-health-in-bariatric-surgery-patients-post-operative-functional-medicine-care

Zheng, Z., Hu, Y., Tang, J., Xu, W., Zhu, W., & Zhang, W. (2023). The implication of gut microbiota in recovery from gastrointestinal surgery. Frontiers in Cellular and Infection Microbiology, 13(1110787). https://doi.org/10.3389/fcimb.2023.1110787

Zuvarox, T., & Belletieri, C. (2024, January). Malabsorption Syndromes. In StatPearls [Internet]. StatPearls Publishing. Available from: https://www.ncbi.nlm.nih.gov/books/NBK553106/

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