Nutrition
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January 9, 2023

How to Use Nutrigenomics Testing to Personalize Your Patients Optimal Diet

Written By
Dr. Jessica Christie ND, CNS
Medically Reviewed by
Updated On
January 14, 2025

According to research, diet is a significant factor influencing overall health and well-being. It's no surprise that many people focus on diet to help maintain their health. Each year, new diets become popular, each claiming to be the best for optimal health. But is there truly one diet that fits everyone? Or is it more accurate to say that there is a diet that best suits YOU for YOUR optimal health, even if it differs from what works for someone else?

Choosing what to eat is undoubtedly important. However, it can be overwhelming due to the numerous diets and expert opinions in the media. If selecting the right diet for you has been challenging, nutrigenomics might offer some clarity by helping to determine your optimal diet based on your unique genetic makeup.

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What is Nutrigenomics?

Nutrigenomics, also known as nutritional genomics, is the study of how genes and nutrition interact. Your genetic variation can provide insights into how your body may respond to different nutrients.

For a long time, genes were considered the fixed blueprints of our bodies. While genes play a crucial role in determining certain health factors, a newer scientific model called epigenetics shows that genes can be influenced by our environment. Since nutrition is a significant part of our internal environment, it can affect which genes are active.

Interestingly, researchers have observed that some individuals may respond positively to certain diets, while others may not experience the same benefits or may even have different reactions. This response is based on the principles of nutrigenomics. By following a personalized diet, individuals may influence which genes are expressed, potentially impacting their overall health.

How Does Nutrigenomic Testing Work?

Genetic testing involves analyzing your DNA to identify variations in your genes that may be associated with health conditions. Nutrigenomic testing is a specific type of genetic test that provides insights into an individual's unique nutritional needs. The test typically requires a cheek swab, which is sent to a lab to examine specific genes.

Once the genes are sequenced, lab companies and healthcare practitioners often use a database to interpret the findings.

The database provides information about specific Single Nucleotide Polymorphisms (SNP - pronounced as "snip") identified in the sample based on current research. These SNPs are variations in a genetic sequence where a single nucleotide is altered. In the context of nutrigenomic testing, the variations evaluated are those associated with common health conditions that have known interactions with specific foods or nutrients.

How Are Genetics And Dietary Needs Linked?

Genetic variability can influence many nutritional processes. For example, genetics can affect nutrient absorption. Individuals with hemochromatosis, a genetic condition, may absorb more iron and might need to manage their iron intake. Similarly, some individuals may not produce enough gastric intrinsic factor, a protein important for transporting certain nutrients. In these cases, Vitamin B12 supplementation might be necessary.

Genetic differences can also influence food and taste preferences, indirectly affecting nutrition because individuals are more likely to eat foods they prefer, which could lead to potential deficiencies.

Several food intolerances, such as lactose intolerance, have a genetic component. Lactose intolerant individuals may need to follow a dairy-free diet and find alternative sources for nutrients like calcium and vitamins A and D.

Genes can also influence metabolism and weight. For instance, some people may require fewer calories due to an efficient metabolism, which could lead to storing excess calories as fat if they overeat. Others may need more calories, making them less likely to store fat.

What's The Difference Between Nutrigenomics & Nutrigenetics

Nutrigenomics and Nutrigenetics are related fields that study the interaction between diet and genes. Nutrigenomics focuses on how diet affects genes and metabolism, aiming to provide personalized nutrition by understanding how diet influences genetic makeup. An example is the association between coffee consumption and a reduced risk of certain health conditions.

On the other hand, nutrigenetics examines how genes influence nutritionally related health conditions or an individual's response to diet. It explores how diet/gene interactions can impact health. For example, individuals may have different cholesterol or blood pressure levels on the same diet due to genetic predispositions.

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Nutrigenomic Testing

There are many at-home genetic lab tests available online. However, the information from these tests can be overwhelming without clear, actionable steps. Here are some options to consider:

If you're interested in nutrigenomics, the Wellness Panel by DNA RX is an option. This test assesses genetics related to diet and lifestyle. It provides actionable steps to help make the information clinically relevant.

The DNA Diet test by dnalife is another example of nutrigenomic testing. It uses genetics to guide personalized diet recommendations, suggesting which diet type, such as low carbohydrate, low fat, or Mediterranean, may align with your genetic variations.

Any Other Lab Test to Check

Sometimes non-genetic tests can complement nutrigenomic tests. For instance, if nutrigenomic testing suggests a predisposition for certain vitamin deficiencies, a micronutrient test can help determine if you currently have any deficiencies.

If your nutrigenomic test indicates a predisposition to neurotransmitter imbalances, an Organic Acids Test might be useful to assess current neurotransmitter status.

How to Use Nutrigenomic Testing for Better Health Outcomes?

Research suggests that people with genetic information about themselves may be more motivated to pursue health and wellness goals. Nutrigenomic testing can be a starting point for improving overall wellness. However, achieving health outcomes requires taking actionable steps.

Working with a healthcare provider knowledgeable in nutrigenomics can help you use the information from these tests to create a plan. Nutrigenomic tests can indicate genetic predispositions to health conditions, but they don't determine your destiny. You can use this information to make dietary choices that support your health.

Summary

Nutrigenomics is an exciting field that connects genetic testing and nutrition. With many fad diets available, it can be challenging to determine the best dietary advice for you. Nutrigenomics offers a genetic assessment that can help tailor a diet to your needs, reducing guesswork.

With nutrigenomic testing and an individualized nutrition plan, you can have tools to support your personal health goals.

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The information in this article is designed for educational purposes only and is not intended to be a substitute for informed medical advice or care. This information should not be used to diagnose or treat any health problems or illnesses without consulting a doctor. Consult with a health care practitioner before relying on any information in this article or on this website.

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Lab Tests in This Article

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  2. Christie, J. (2022, September 13). It's time to start treating coffee like a health food. Rupa Health. https://www.rupahealth.com/post/its-time-to-start-treating-coffee-like-a-health-food
  3. Genetic influences on weight. (2021, December 27). MyHealth.Alberta.ca. https://myhealth.alberta.ca/Health/Pages/conditions.aspx?hwid=ug1798
  4. Genetic testing. (2020, April 14). Mayo Clinic - Mayo Clinic. https://www.mayoclinic.org/tests-procedures/genetic-testing/about/pac-20384827
  5. Home - SNP - NCBI. (2021, January 6). National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/snp/
  6. How Nutrigenomics may impact the way you eat. (2022, May 9). Cleveland Clinic. https://health.clevelandclinic.org/how-does-nutrigenomics-work/
  7. Locke, A., Schneiderhan, J., & Zick, S. M. (2018). Diets for health: Goals and guidelines. American Family Physician, 97(11), 721-728. https://www.aafp.org/pubs/afp/issues/2018/0601/p721.html
  8. Mead, M. N. (2007). Nutrigenomics: The genome–food interface. Environmental Health Perspectives, 115(12). https://doi.org/10.1289/ehp.115-a582
  9. National Research Council (US) Committee on Diet and Health. (1989). Genetics and Nutrition. In Diet and health: Implications for reducing chronic disease risk. National Academies Press. https://www.ncbi.nlm.nih.gov/books/NBK218767/#_NBK218767_pubdet_
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  11. NCI Dictionary of genetics terms. (2022). National Cancer Institute. https://www.cancer.gov/publications/dictionaries/genetics-dictionary/def/snp
  12. Ramos-Lopez, O., Milagro, F. I., Allayee, H., Chmurzynska, A., Choi, M. S., Curi, R., De Caterina, R., Ferguson, L. R., Goni, L., Kang, J. X., Kohlmeier, M., Marti, A., Moreno, L. A., Pérusse, L., Prasad, C., Qi, L., Reifen, R., Riezu-Boj, J. I., San-Cristobal, R., … Martínez, J. A. (2017). Guide for current Nutrigenetic, Nutrigenomic, and Nutriepigenetic approaches for precision nutrition involving the prevention and management of chronic diseases associated with obesity. Lifestyle Genomics, 10(1-2), 43-62. https://doi.org/10.1159/000477729
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