Dermatology
|
December 20, 2023

Hyperglycemia and Skin Health: The Connection You May Have Never Heard About

Medically Reviewed by
Updated On
September 18, 2024

Let’s get real about blood sugar – it’s not just a numbers game. Hyperglycemia, or high blood sugar, isn’t content with stirring things up on the inside; it’s got its eyes set on your skin, too. As more people deal with blood sugar challenges, it’s time to shed some light on what this means for your complexion.

Sure, you’re keeping an eye on those blood sugar levels for how they impact your internal health. But hyperglycemia is also quietly wreaking havoc on your skin as well. 

It’s not just about complex calculations; it’s a story of how those blood sugar numbers shape your skin's look and feel. Let’s dive into this together – exploring how inflammation, collagen, and your skin’s defense mechanisms are all part of hyperglycemia’s impact on your skin health. 

There is no jargon, just plain talk about how hyperglycemia isn’t just a behind-the-scenes player; it’s right there, affecting how your skin shows up in the world.  

[signup]

What is Hyperglycemia?

Hyperglycemia, simply put, is when the sugar levels in your blood soar higher than the norm. (1) It’s like a blood sugar roller coaster that, if left unchecked, can lead to some serious health issues.

Now, what’s causing this sugar surge?

This spike in sugar is often associated with diabetes, a condition that disrupts the usual regulation of blood sugar. In a well-regulated system, insulin, a hormone from the pancreas, acts like a key, enabling cells to absorb glucose for energy. However, diabetes throws a wrench into this process.

In type 1 diabetes, the body produces insufficient insulin, leaving excess glucose in the bloodstream. (2) In type 2 diabetes, cells become resistant to insulin, impeding glucose absorption. (3) The consequence is elevated blood sugar levels, giving rise to hyperglycemia.

Normally, our bodies do a good job maintaining our blood sugar levels. When we eat, blood sugar rises; when we haven’t eaten for a while, it decreases. However, during hyperglycemia, this balance is disrupted. 

Excess glucose lingers, causing disruptions. 

This imbalance can affect various aspects of our health, including energy levels and, as we’re discovering, the health of our skin. Monitoring blood sugar levels isn’t just about numbers; it’s about preserving a stable equilibrium for your overall well-being.

The Skin: Our Largest Organ

Your skin is more than a surface – it’s a dynamic organ with layers working in harmony. (4) The outer layer, the epidermis, protects against the outside world, while the dermis supports crucial structures like glands and hair follicles. The subcutaneous tissue underneath provides insulation and cushioning. Yet, the significance of your skin goes beyond its structural brilliance.

Consider your skin as a visible health barometer.

Changes in your skin’s appearance often reflect internal shifts. (5) Conditions like hyperglycemia, impacting internal systems, can also manifest in your skin. It becomes a messenger, signaling potential health issues. Whether it’s a subtle change in color, dryness, or inflammation, your skin communicates with you.

Your skin’s involvement in overall health is not just skin-deep; it’s an active participant in your well-being. It’s a mirror reflecting your internal harmony or an imbalance. By paying attention to your skin, you can gain insights into your body, allowing you to address potential health concerns before they escalate. 

Hyperglycemia and Skin Complications

Skin, being the largest organ, doesn’t escape the influence of hyperglycemia. Elevated blood sugar levels can trigger various skin conditions. There are three primary skin conditions associated with hyperglycemia, including:

1. Diabetic Dermopathy

Characterized by light brown, scaly patches that often appear on the shins, diabetic dermopathy is considered a telltale sign of prolonged hyperglycemia. (6) Elevated blood sugar levels contribute to this skin condition by impairing the small blood vessels that supply the skin, diminishing blood flow, and leading to distinctive patches. Chronic hyperglycemia also affects the structure of collagen, the skin's supportive protein, exacerbating dryness due to impaired nerve function.  

2. Increased Infection Risk

Hyperglycemia weakens the immune response and hinders the skin's ability to resist intruders, creating favorable conditions for bacteria, fungi, and yeast growth. (7) This compromised defense allows these microorganisms to thrive, resulting in discomfort and irritation. 

3. Delayed Wound Healing

When the body experiences a minor cut or injury, the usual mechanisms that orchestrate healing are disrupted due to hyperglycemia. (8) The impaired tissue regeneration under high glucose conditions leads to slower healing times for cuts and injuries.

Other skin conditions linked to hyperglycemia or considered diabetic skin conditions can include: (9, 10)

  • Acanthosis Nigricans
  • Xerosis (Dry Skin)
  • Pruritus (Itchy Skin)
  • Cellulitis
  • Necrobiosis Lipoidica Diabeticorum 

The Biochemical Link: Glucose and Collagen

The glycation process in the skin is a biochemical reaction where sugars attach to proteins, altering their structure and functionality. (11) In skin health, collagen and elastin, the proteins responsible for maintaining skin firmness and elasticity, are particularly susceptible.

When hyperglycemia prevails, it accelerates glycation, forming advanced glycation end products (AGEs). These AGEs contribute to the degradation of collagen and elastin fibers, causing them to become stiff, brittle, and less effective in providing the skin with its youthful resilience.

This relentless glycation-induced alteration of collagen and elastin is a critical player in skin aging. The skin loses its natural suppleness, forming wrinkles, fine lines, and sagging. The impaired function of collagen and elastin due to hyperglycemia also compromises the skin barrier. This weakened barrier makes the skin more susceptible to external aggressors and moisture loss and impedes its ability to repair and regenerate.

Preventive and Management Strategies For Skin Health

When it comes to managing hyperglycemia for skin health, a holistic approach is key, combining dietary, lifestyle, and medical interventions to safeguard the skin's vitality.

Dietary Strategies

Start by curating a balanced diet that prioritizes whole foods that are low in refined sugars and carbohydrates. Incorporate nutrient-rich options like fruits, vegetables, lean proteins, and whole grains. These choices promote stable blood sugar levels and provide essential vitamins and antioxidants crucial for skin health. Staying hydrated is equally important, as water helps flush out toxins and supports overall skin hydration.

Lifestyle Adjustments

Regular physical activity is a powerful ally in blood sugar management. Engaging in moderate exercise not only aids in glucose regulation but also enhances blood circulation, benefiting skin health. Prioritize stress management through techniques like meditation or yoga, as stress can contribute to blood sugar spikes. Ensure consistent, quality sleep, as inadequate rest can disrupt hormonal balance, impacting blood sugar control and skin rejuvenation.

Medical Interventions

For those with diabetes, adhering to prescribed medications and insulin therapy is fundamental. Regular monitoring of blood glucose levels allows for proactive adjustments to maintain optimal control. Consult with healthcare professionals to create a personalized diabetes management plan that considers skin health.

Preventive Strategies for Skin Care

Prioritize skincare routines, including gentle cleansing and moisturizing, to protect the skin barrier. Sun protection is non-negotiable, as prolonged sun exposure can exacerbate skin issues. Regular skin checks for early detection of potential concerns are also prudent.

Managing blood sugar levels isn't just about glycemic control; it's a holistic investment in skin health. By integrating these preventive strategies for skin care into daily life, you can proactively shield their skin from the impact of hyperglycemia and foster a foundation for long-term skin vitality.

The Role of Functional Medicine in Managing Hyperglycemia

Functional medicine offers a refreshing perspective, viewing individuals not just as a collection of symptoms but as holistic beings with unique health stories. When it comes to hyperglycemia, functional medicine takes a deep dive into the root causes, aiming for a nuanced understanding.

Picture this: a plan designed exclusively for you. Your dietary choices become a crucial tool, emphasizing whole, nutrient-rich foods to maintain stable blood sugar levels. Exercise recommendations are fine-tuned, strategically aiding in blood sugar control. Stress management techniques become integral, addressing the emotional aspects that contribute to hyperglycemia.

But there's more to the functional medicine toolkit. It may introduce supplements – specific nutrients or herbs – to fortify your body's efforts in handling blood sugar fluctuations.

In essence, functional medicine serves as your personalized guide for navigating hyperglycemia. Think of it as having a health companion who tailors strategies to your unique needs. It's a comprehensive approach, weaving together dietary shifts, lifestyle adjustments, and targeted supplementation, empowering you to take charge of your blood sugar in a way that aligns with your individual journey to well-being.

Functional Medicine Lab Testing For Hyperglycemia and Skin Health

In functional medicine, a crucial aspect of managing hyperglycemia and assessing its impact on skin health involves targeted lab tests that go beyond conventional evaluations. These specialized lab tests for hyperglycemia provide a more nuanced understanding of your metabolic landscape.

Functional medicine lab testing for hyperglycemia can include:

Blood Glucose Level Test: This single marker Blood Glucose Test offered by Access Medical Laboratories provides an immediate snapshot of glycemic status.

HbA1c Test: This HbA1c test offered by Ayumetrix measures average blood sugar levels over a few months, offering a comprehensive overview.

Fasting Insulin Level Test: The Fasting Insulin Test offered by Access Med Labs assesses insulin resistance, a key indicator of hyperglycemia and diabetes.

Glycated Albumin (GA): The GA test offered by Access Med Labs provides insight into short-term glycemic control, complementing the information obtained from HbA1c.

Homocysteine Levels: Elevated homocysteine levels offered by Access Med Labs may indicate impaired methylation, which is linked to hyperglycemia and can contribute to various health issues.

Inflammatory Marker Tests:

C-reactive Protein (CRP): CRP offered by Access Med Labs Indicates systemic inflammation.

Interleukin-6 (IL-6): IL-6 offered by BostonHeart Diagnostics provides insights into the inflammatory impact of chronic hyperglycemia.

Lipid Profile: Assessing lipid parameters, including cholesterol levels and triglycerides, the Lipid Profile Test offered by Access Med Labs can contribute to a broader understanding of metabolic health associated with hyperglycemia.

These specialized lab tests for hyperglycemia go beyond the conventional, offering a more nuanced understanding of an individual's metabolic health. When monitoring skin health medically, these tests become crucial tools in functional medicine, allowing practitioners to tailor personalized strategies for managing hyperglycemia and addressing its potential impact on the skin with precision.

Holistic Skin Care Approaches

Incorporating holistic skin care practices becomes a crucial ally in promoting skin health in tandem with managing hyperglycemia through medical and functional approaches.

A Mindful Daily Skincare Routine Works Wonders

Start your routine with a gentle cleanser that removes impurities without stripping away the skin's natural oils. (12) This maintains the skin's balance and prevents excessive dryness or oiliness.

Opt for skincare products that are natural and non-toxic. Seek ingredients like aloe vera, known for its soothing and hydrating properties, along with chamomile and calendula, which provide calming benefits, making them ideal for sensitive or stressed skin.

Hydration is Paramount

Choose a moisturizer that contains ingredients such as hyaluronic acid, a powerful hydrating agent that helps the skin retain moisture. (13) Natural oils like jojoba or argan oil further contribute to maintaining skin suppleness.

Sun Protection is Non-Negotiable

Prioritize sun protection by selecting a broad-spectrum sunscreen with at least SPF 30. This shields the skin from harmful UV rays, preventing sun damage and premature aging and reducing the risk of skin cancers.

Natural Skin Treatments Contribute to Nourishment

Integrate natural skin treatments into your routine, like DIY masks featuring ingredients such as honey, known for its antibacterial properties, turmeric with anti-inflammatory benefits, and yogurt, offering gentle exfoliation. (14) These ingredients collectively contribute to nourishment, promote a healthy skin barrier, and provide anti-inflammatory and antioxidant benefits.

[signup]

Hyperglycemia and Skin Health: Key Takeaways 

A holistic approach extends beyond external care. Staying hydrated, adopting stress-management practices like meditation, and ensuring a balanced diet rich in antioxidants further support skin vitality. Embracing holistic skin care for hyperglycemia involves a symbiotic relationship between internal health management and external nurturing, fostering overall well-being from the inside out.

Recognizing the direct influence of hyperglycemia on skin health is pivotal for overall well-being. It's not just about monitoring blood sugar; our skin is a visible indicator of internal health. Adopting a straightforward and practical approach involves incorporating personalized dietary plans, functional medicine insights, and a straightforward skincare routine. By understanding the intricate connection between blood sugar levels and skin vitality, we empower ourselves to prevent skin issues associated with hyperglycemia proactively. Managing blood sugar becomes more than a medical necessity; it becomes a pathway to maintaining a radiant and resilient exterior.

Taking tangible steps, like choosing natural skincare products and embracing a balanced lifestyle, supports this holistic approach. Skin health is an integral part of our overall wellness journey, and acknowledging its relationship with hyperglycemia reinforces the importance of a comprehensive strategy. 

So, let's commit to practical, everyday choices, fostering a harmonious balance that benefits both our internal health and the vibrancy of our skin.

Let’s get real about blood sugar – it’s not just a numbers game. Hyperglycemia, or high blood sugar, can have effects beyond internal health; it may also influence your skin. As more people manage blood sugar challenges, it’s important to understand what this means for your complexion.

While monitoring blood sugar levels is crucial for internal health, hyperglycemia might also affect your skin's appearance.

It’s not just about complex calculations; it’s a story of how those blood sugar numbers might influence your skin's look and feel. Let’s explore how inflammation, collagen, and your skin’s defense mechanisms are all part of hyperglycemia’s potential impact on your skin health.

There is no jargon, just plain talk about how hyperglycemia might be affecting how your skin shows up in the world.

[signup]

What is Hyperglycemia?

Hyperglycemia, simply put, is when the sugar levels in your blood are higher than the norm. (1) It’s like a blood sugar roller coaster that, if left unchecked, can lead to some health issues.

Now, what’s causing this sugar surge?

This spike in sugar is often associated with diabetes, a condition that disrupts the usual regulation of blood sugar. In a well-regulated system, insulin, a hormone from the pancreas, acts like a key, enabling cells to absorb glucose for energy. However, diabetes can disrupt this process.

In type 1 diabetes, the body produces insufficient insulin, leaving excess glucose in the bloodstream. (2) In type 2 diabetes, cells become resistant to insulin, impeding glucose absorption. (3) The consequence is elevated blood sugar levels, giving rise to hyperglycemia.

Normally, our bodies do a good job maintaining our blood sugar levels. When we eat, blood sugar rises; when we haven’t eaten for a while, it decreases. However, during hyperglycemia, this balance is disrupted.

Excess glucose lingers, potentially causing disruptions.

This imbalance can affect various aspects of our health, including energy levels and, as we’re discovering, the health of our skin. Monitoring blood sugar levels isn’t just about numbers; it’s about preserving a stable equilibrium for your overall well-being.

The Skin: Our Largest Organ

Your skin is more than a surface – it’s a dynamic organ with layers working in harmony. (4) The outer layer, the epidermis, protects against the outside world, while the dermis supports crucial structures like glands and hair follicles. The subcutaneous tissue underneath provides insulation and cushioning. Yet, the significance of your skin goes beyond its structural brilliance.

Consider your skin as a visible health barometer.

Changes in your skin’s appearance often reflect internal shifts. (5) Conditions like hyperglycemia, impacting internal systems, can also manifest in your skin. It becomes a messenger, signaling potential health issues. Whether it’s a subtle change in color, dryness, or inflammation, your skin communicates with you.

Your skin’s involvement in overall health is not just skin-deep; it’s an active participant in your well-being. It’s a mirror reflecting your internal harmony or an imbalance. By paying attention to your skin, you can gain insights into your body, allowing you to address potential health concerns before they escalate.

Hyperglycemia and Skin Complications

Skin, being the largest organ, may be influenced by hyperglycemia. Elevated blood sugar levels can be associated with various skin conditions. There are three primary skin conditions associated with hyperglycemia, including:

1. Diabetic Dermopathy

Characterized by light brown, scaly patches that often appear on the shins, diabetic dermopathy is considered a sign of prolonged hyperglycemia. (6) Elevated blood sugar levels may contribute to this skin condition by affecting the small blood vessels that supply the skin, diminishing blood flow, and leading to distinctive patches. Chronic hyperglycemia can also affect the structure of collagen, the skin's supportive protein, potentially exacerbating dryness due to impaired nerve function.

2. Increased Infection Risk

Hyperglycemia may weaken the immune response and hinder the skin's ability to resist intruders, creating favorable conditions for bacteria, fungi, and yeast growth. (7) This compromised defense allows these microorganisms to thrive, resulting in discomfort and irritation.

3. Delayed Wound Healing

When the body experiences a minor cut or injury, the usual mechanisms that orchestrate healing may be disrupted due to hyperglycemia. (8) The impaired tissue regeneration under high glucose conditions can lead to slower healing times for cuts and injuries.

Other skin conditions linked to hyperglycemia or considered diabetic skin conditions can include: (9, 10)

  • Acanthosis Nigricans
  • Xerosis (Dry Skin)
  • Pruritus (Itchy Skin)
  • Cellulitis
  • Necrobiosis Lipoidica Diabeticorum

The Biochemical Link: Glucose and Collagen

The glycation process in the skin is a biochemical reaction where sugars attach to proteins, altering their structure and functionality. (11) In skin health, collagen and elastin, the proteins responsible for maintaining skin firmness and elasticity, are particularly susceptible.

When hyperglycemia prevails, it may accelerate glycation, forming advanced glycation end products (AGEs). These AGEs can contribute to the degradation of collagen and elastin fibers, causing them to become stiff, brittle, and less effective in providing the skin with its youthful resilience.

This glycation-induced alteration of collagen and elastin is a critical player in skin aging. The skin may lose its natural suppleness, forming wrinkles, fine lines, and sagging. The impaired function of collagen and elastin due to hyperglycemia can also compromise the skin barrier. This weakened barrier makes the skin more susceptible to external aggressors and moisture loss and may impede its ability to repair and regenerate.

Preventive and Management Strategies For Skin Health

When it comes to managing hyperglycemia for skin health, a holistic approach is key, combining dietary, lifestyle, and medical interventions to support the skin's vitality.

Dietary Strategies

Consider curating a balanced diet that prioritizes whole foods that are low in refined sugars and carbohydrates. Incorporate nutrient-rich options like fruits, vegetables, lean proteins, and whole grains. These choices may help promote stable blood sugar levels and provide essential vitamins and antioxidants crucial for skin health. Staying hydrated is equally important, as water helps flush out toxins and supports overall skin hydration.

Lifestyle Adjustments

Regular physical activity can be a powerful ally in blood sugar management. Engaging in moderate exercise may aid in glucose regulation and enhance blood circulation, benefiting skin health. Prioritize stress management through techniques like meditation or yoga, as stress can contribute to blood sugar spikes. Ensure consistent, quality sleep, as inadequate rest can disrupt hormonal balance, impacting blood sugar control and skin rejuvenation.

Medical Interventions

For those with diabetes, adhering to prescribed medications and insulin therapy is fundamental. Regular monitoring of blood glucose levels allows for proactive adjustments to maintain optimal control. Consult with healthcare professionals to create a personalized diabetes management plan that considers skin health.

Preventive Strategies for Skin Care

Prioritize skincare routines, including gentle cleansing and moisturizing, to protect the skin barrier. Sun protection is important, as prolonged sun exposure can exacerbate skin issues. Regular skin checks for early detection of potential concerns are also prudent.

Managing blood sugar levels isn't just about glycemic control; it's a holistic investment in skin health. By integrating these preventive strategies for skin care into daily life, you can proactively support your skin from the impact of hyperglycemia and foster a foundation for long-term skin vitality.

The Role of Functional Medicine in Managing Hyperglycemia

Functional medicine offers a refreshing perspective, viewing individuals not just as a collection of symptoms but as holistic beings with unique health stories. When it comes to hyperglycemia, functional medicine takes a deep dive into the root causes, aiming for a nuanced understanding.

Picture this: a plan designed exclusively for you. Your dietary choices become a crucial tool, emphasizing whole, nutrient-rich foods to maintain stable blood sugar levels. Exercise recommendations are fine-tuned, strategically aiding in blood sugar control. Stress management techniques become integral, addressing the emotional aspects that contribute to hyperglycemia.

But there's more to the functional medicine toolkit. It may introduce supplements – specific nutrients or herbs – to support your body's efforts in handling blood sugar fluctuations.

In essence, functional medicine serves as your personalized guide for navigating hyperglycemia. Think of it as having a health companion who tailors strategies to your unique needs. It's a comprehensive approach, weaving together dietary shifts, lifestyle adjustments, and targeted supplementation, empowering you to take charge of your blood sugar in a way that aligns with your individual journey to well-being.

Functional Medicine Lab Testing For Hyperglycemia and Skin Health

In functional medicine, a crucial aspect of managing hyperglycemia and assessing its impact on skin health involves targeted lab tests that go beyond conventional evaluations. These specialized lab tests for hyperglycemia provide a more nuanced understanding of your metabolic landscape.

Functional medicine lab testing for hyperglycemia can include:

Blood Glucose Level Test: This single marker Blood Glucose Test offered by Access Medical Laboratories provides an immediate snapshot of glycemic status.

HbA1c Test: This HbA1c test offered by Ayumetrix measures average blood sugar levels over a few months, offering a comprehensive overview.

Fasting Insulin Level Test: The Fasting Insulin Test offered by Access Med Labs assesses insulin resistance, a key indicator of hyperglycemia and diabetes.

Glycated Albumin (GA): The GA test offered by Access Med Labs provides insight into short-term glycemic control, complementing the information obtained from HbA1c.

Homocysteine Levels: Elevated homocysteine levels offered by Access Med Labs may indicate impaired methylation, which is linked to hyperglycemia and can contribute to various health issues.

Inflammatory Marker Tests:

C-reactive Protein (CRP): CRP offered by Access Med Labs Indicates systemic inflammation.

Interleukin-6 (IL-6): IL-6 offered by BostonHeart Diagnostics provides insights into the inflammatory impact of chronic hyperglycemia.

Lipid Profile: Assessing lipid parameters, including cholesterol levels and triglycerides, the Lipid Profile Test offered by Access Med Labs can contribute to a broader understanding of metabolic health associated with hyperglycemia.

These specialized lab tests for hyperglycemia go beyond the conventional, offering a more nuanced understanding of an individual's metabolic health. When monitoring skin health medically, these tests become crucial tools in functional medicine, allowing practitioners to tailor personalized strategies for managing hyperglycemia and addressing its potential impact on the skin with precision.

Holistic Skin Care Approaches

Incorporating holistic skin care practices becomes a crucial ally in promoting skin health in tandem with managing hyperglycemia through medical and functional approaches.

A Mindful Daily Skincare Routine Works Wonders

Start your routine with a gentle cleanser that removes impurities without stripping away the skin's natural oils. (12) This maintains the skin's balance and prevents excessive dryness or oiliness.

Opt for skincare products that are natural and non-toxic. Seek ingredients like aloe vera, known for its soothing and hydrating properties, along with chamomile and calendula, which provide calming benefits, making them ideal for sensitive or stressed skin.

Hydration is Paramount

Choose a moisturizer that contains ingredients such as hyaluronic acid, a powerful hydrating agent that helps the skin retain moisture. (13) Natural oils like jojoba or argan oil further contribute to maintaining skin suppleness.

Sun Protection is Important

Prioritize sun protection by selecting a broad-spectrum sunscreen with at least SPF 30. This shields the skin from harmful UV rays, helping to prevent sun damage and premature aging and reducing the risk of skin cancers.

Natural Skin Treatments Contribute to Nourishment

Integrate natural skin treatments into your routine, like DIY masks featuring ingredients such as honey, known for its antibacterial properties, turmeric with anti-inflammatory benefits, and yogurt, offering gentle exfoliation. (14) These ingredients collectively contribute to nourishment, promote a healthy skin barrier, and provide anti-inflammatory and antioxidant benefits.

[signup]

Hyperglycemia and Skin Health: Key Takeaways

A holistic approach extends beyond external care. Staying hydrated, adopting stress-management practices like meditation, and ensuring a balanced diet rich in antioxidants further support skin vitality. Embracing holistic skin care for hyperglycemia involves a symbiotic relationship between internal health management and external nurturing, fostering overall well-being from the inside out.

Recognizing the potential influence of hyperglycemia on skin health is pivotal for overall well-being. It's not just about monitoring blood sugar; our skin can be a visible indicator of internal health. Adopting a straightforward and practical approach involves incorporating personalized dietary plans, functional medicine insights, and a straightforward skincare routine. By understanding the intricate connection between blood sugar levels and skin vitality, we empower ourselves to proactively support skin health. Managing blood sugar becomes more than a medical necessity; it becomes a pathway to maintaining a radiant and resilient exterior.

Taking tangible steps, like choosing natural skincare products and embracing a balanced lifestyle, supports this holistic approach. Skin health is an integral part of our overall wellness journey, and acknowledging its relationship with hyperglycemia reinforces the importance of a comprehensive strategy.

So, let's commit to practical, everyday choices, fostering a harmonious balance that benefits both our internal health and the vibrancy of our skin.

The information provided is not intended to be a substitute for professional medical advice. Always consult with your doctor or other qualified healthcare provider before taking any dietary supplement or making any changes to your diet or exercise routine.

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Lab Tests in This Article

Alves, Cresio. “Infections in patients with diabetes mellitus: A review of pathogenesis.” NCBI, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3354930/. Accessed 15 December 2023.

“The Causes of Insulin Resistance in Type 1 Diabetes Mellitus: Is There a Place for Quaternary Prevention?” NCBI, 21 November 2020, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700208/. Accessed 15 December 2023.

“Clinical Significance of Diabetic Dermatopathy - PMC.” NCBI, 8 December 2020, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733392/. Accessed 15 December 2023.

“Diabetes and Skin Complications | ADA.” American Diabetes Association, https://diabetes.org/about-diabetes/complications/skin-complications. Accessed 15 December 2023.

“Diabetes and Your Skin.” CDC, 14 June 2022, https://www.cdc.gov/diabetes/library/features/diabetes-and-your-skin.html . Accessed 15 December 2023.

“Healing, Inflammation, and Fibrosis: Updates in Diabetic Wound Healing, Inflammation, and Scarring.” NCBI, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432997/. Accessed 15 December 2023.

“Hyperglycemia - StatPearls.” NCBI, 24 April 2023, https://www.ncbi.nlm.nih.gov/books/NBK430900/. Accessed 15 December 2023.

Kligman, Albert M. “What is the 'true' function of skin?” NCBI, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010069/. Accessed 15 December 2023.

“Research Advances on the Damage Mechanism of Skin Glycation and Related Inhibitors.” NCBI, 1 November 2022, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655929/. Accessed 15 December 2023.

“Skin manifestations associated with systemic diseases – Part II.” NCBI, 17 September 2021, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790166/. Accessed 15 December 2023.

Taylor, Roy. “Insulin Resistance and Type 2 Diabetes - PMC.” NCBI, 14 March 2012, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314346/. Accessed 15 December 2023.

“Honey: A Therapeutic Agent for Disorders of the Skin.” NCBI, 4 August 2016, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661189/. Accessed 18 December 2023.

“Hyaluronic acid: A key molecule in skin aging.” NCBI, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583886/. Accessed 18 December 2023.

Mukhopadhyay, Partha. “Cleansers and their role in various dermatological disorders.” NCBI, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088928/. Accessed 18 December 2023.

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