Research Studies
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November 19, 2024

How Lowering Salt Intake Could Help with Atopic Dermatitis

Written By
Medically Reviewed by
Dr. Ayesha Bryant MSPH, MD
Updated On
December 23, 2024

Atopic dermatitis (AD) is a common skin condition that results in persistent itching and irritated skin. It often disrupts daily life, and its unpredictable flare-ups can make managing the condition frustrating. 

While many people rely on medications and creams for relief, something as simple as reducing salt intake, a common part of many meals, may help ease AD symptoms, offering a straightforward and practical approach to managing the condition.

In 2024, a cross-sectional study published in JAMA Dermatology explored the potential connection between dietary sodium intake and atopic dermatitis. The researchers aimed to understand whether salt consumption might influence the severity of this skin condition, offering new insights into how diet could play a role in managing AD symptoms

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The Study At A Glance

This cross-sectional study explored the link between dietary sodium intake and atopic dermatitis (AD), a chronic skin condition. The researchers investigated whether higher salt intake could influence the presence and severity of AD, offering insights into dietary changes as a potential non-pharmaceutical option for managing the condition.

Data from the UK Biobank was used, with 215,832 adults aged 37 to 73. The diverse participant pool, covering various ethnicities, genders, and socio-economic backgrounds, ensured the findings could be broadly applicable. The large sample size increased the study’s reliability and statistical significance.

The researchers analyzed urine samples to estimate sodium intake, providing an objective snapshot of daily salt consumption. Using a specialized equation, they adjusted for factors like body mass index, age, and other electrolytes in the urine to estimate 24-hour sodium excretion accurately.

Medical records were cross-referenced to identify participants with AD, allowing the study to examine the relationship between sodium levels and both the presence and severity of the condition. This detailed approach provided a good foundation for the research findings.

The Key Findings of the Study

The study found a clear link between higher salt intake and an increased likelihood of having atopic dermatitis (AD). 

It details how each extra gram of daily salt raises the odds of being diagnosed with AD by 11%, worsens symptoms for those already diagnosed, and links a 1-gram increase in daily intake to a 16% higher chance of active AD.
  • For each additional gram of salt consumed daily, the odds of being diagnosed with AD increased by 11%. 
  • A 1-gram increase in daily salt intake was also linked to a 16% higher chance of having active AD.
  • For those already diagnosed with AD, higher salt intake was associated with more severe symptoms. 
  • This relationship remained consistent even after statistically adjusting for age, sex, race, ethnicity, and socio-economic factors.

Significance of the Findings

The findings suggest that reducing salt intake could provide a simple, cost-effective, and low-risk way to help manage atopic dermatitis (AD). 

This approach could serve as a complementary or alternative treatment to the medications currently used to manage AD, offering a more accessible solution for many people dealing with this chronic skin condition.

Given that AD can be challenging to treat and often requires ongoing medical interventions, the potential for a dietary change like reducing salt intake is especially valuable. 

Diet has been shown to influence skin conditions, but this approach is unique in exploring the role of salt intake, which has received little attention in AD.

Clinical Application

Future studies confirming these findings could transform how physicians treat atopic dermatitis (AD). Instead of relying solely on medications, doctors may begin recommending dietary changes, such as reducing salt intake, as part of treatment.

By incorporating salt reduction into holistic treatment plans, physicians could make dietary adjustments a central aspect of managing AD. This would provide patients with a more comprehensive approach, combining traditional therapies with practical lifestyle changes. 

These findings also carry broader implications for nutritionists and policymakers. Encouraging lower salt consumption could become a public health strategy to address AD on a larger scale, potentially benefiting many globally affected individuals.

Limitations of the Study

This study has several limitations, one being using a single urine sample to estimate sodium intake. Since sodium consumption can vary daily, this method may not fully capture long-term dietary habits, potentially affecting the accuracy of the findings.

Factors like hydration levels or short-term dietary changes during sampling could also influence sodium measurements, limiting the generalizability of the results and how well they represent typical daily intake over time.

Another limitation is the observational study design. While the findings suggest a link between higher salt intake and more severe AD symptoms, the study cannot prove salt is the direct cause. Observational studies show associations but cannot rule out other factors influencing salt intake and AD severity.

More robust studies, such as randomized controlled trials, are needed to confirm whether reducing salt intake directly improves AD symptoms.

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Key Takeaways

  • The study identifies a potential connection between high sodium intake and aggravated atopic dermatitis (AD) symptoms, suggesting that reducing salt in the diet could be an effective and straightforward method for managing the condition.
  • A low-sodium diet could provide individuals with AD with a safe, accessible way to reduce symptoms, working alongside traditional treatments like medications and topical therapies.
  • This dietary adjustment is simple to adopt and should be considered part of an overall AD management strategy in consultation with healthcare professionals.

Disclaimer: The information provided in this article is for educational purposes only and is not intended as medical advice. Reducing salt intake may not alleviate atopic dermatitis (AD) symptoms for everyone, as individual responses can vary. It's important to consult with your healthcare provider or a qualified medical professional before making any significant changes to your diet or treatment plan. They can offer personalized advice and ensure that any adjustments are safe and appropriate for your specific health needs.

The information in this article is designed for educational purposes only and is not intended to be a substitute for informed medical advice or care. This information should not be used to diagnose or treat any health problems or illnesses without consulting a doctor. Consult with a health care practitioner before relying on any information in this article or on this website.

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Lab Tests in This Article

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Achuff, J. (2024a, September 19). Eczema in babies and children: Signs, symptoms, and care tips. Rupa Health. https://www.rupahealth.com/post/eczema-in-babies-and-children-signs-symptoms-and-care-tips

Achuff, J. (2024b, September 19). How to manage eczema flare-ups. Rupa Health. https://www.rupahealth.com/post/how-to-manage-eczema-flare-ups

Chiang, B. M., Ye, M., Chattopadhyay, A., Yagmur Halezeroglu, Van, E. L., & Abuabara, K. (2024). Sodium intake and atopic dermatitis. JAMA Dermatology. https://doi.org/10.1001/jamadermatol.2024.1544

Cleveland clinic. (2018). Body mass index (BMI). Cleveland Clinic. https://my.clevelandclinic.org/health/articles/9464-body-mass-index-bmi

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Khakham, C. (2023, August 4). Top labs to run bi-annually on your eczema patients. Rupa Health. https://www.rupahealth.com/post/top-labs-to-run-bi-annually-on-your-eczema-patients

Preston, J. (2023, November 17). Nutrition’s role in healthy vibrant skin. Rupa Health. https://www.rupahealth.com/post/nutritions-role-in-healthy-vibrant-skin

Sweetnich, J. (2023, March 15). Sodium 101: Lab tests, disorders, & how much to consume daily. Rupa Health. https://www.rupahealth.com/post/sodium-101

UK Biobank. (2019). UK biobank. Ukbiobank.ac.uk; UK Biobank. https://www.ukbiobank.ac.uk/

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