Nutrition
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December 12, 2024

How Bovine Colostrum May Support Immune Health and Recovery

Medically Reviewed by
Updated On
December 20, 2024

Did you know that the very first milk a cow produces after giving birth can do wonders for human health? This unique substance, called bovine colostrum, is essential for newborn calves and offers incredible health benefits for humans.Β 

Bovine colostrum is increasingly recognized for its potential to support immune health, digestive balance, and post-exercise recovery. This nutrient-rich supplement offers a variety of compounds that may enhance overall well-being.

This guide covers everything you need to know about bovine colostrum: what it is, its nutritional components, the science-backed benefits it offers, how to use it, and the controversies surrounding its use.Β 

This resource provides actionable insights, whether you're a health enthusiast, a practitioner exploring natural supplements, or someone simply looking for ways to feel better.

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What Is Bovine Colostrum?

To understand the remarkable health benefits of bovine colostrum, it's essential first to explore its origins and the unique composition that sets it apart from regular milk.

Definition and Origin

Bovine colostrum is the first milk cows produce within 24–48 hours after giving birth. It is not the same as the milk we typically drink.Β 

Colostrum is thick, yellowish, and nutrient-dense, explicitly designed to support the newborn calf's immune system, gut development, and growth.

These bioactive compounds have been studied for their potential to support immunity, digestion, and tissue repair in humans.

The colostrum used in supplements is collected ethically, ensuring calves receive what they need before any surplus is processed for human consumption. The milk is then pasteurized to maintain its nutrient profile and is available in powders, capsules, or liquids.

Nutritional Composition

What makes bovine colostrum so unique is its impressive array of bioactive nutrients. Here's a closer look at its components:

Bovine Colostrum vs. Regular Milk

While regular milk contains nutrients essential for daily health, bovine colostrum is far more concentrated in its bioactive compounds. Let's compare:

The higher concentration of bioactive nutrients in colostrum may offer additional support for immunity, recovery, and gut health compared to regular milk.

Health Benefits of Bovine Colostrum

Bovine colostrum's unique properties make it a powerful ally for immune health, digestive balance, and athletic performance. Below, we'll unpack how this superfood supports overall well-being.

1. Immune System Support

A strong immune system is the cornerstone of good health, and bovine colostrum is rich in compounds that enhance immune function.

How It Works

  • Immunoglobulins (Antibodies): These specialized proteins act as the body's defense system, neutralizing harmful pathogens like bacteria, viruses, and toxins before they can cause illness.
  • Lactoferrin: A potent antimicrobial protein that helps prevent the growth of pathogenic bacteria and viruses while enhancing the body's natural immune response.
  • Proline-rich polypeptides (PRPs): PRPs help balance immune system activity. They enhance the immune response when needed but can also suppress overactive immune reactions, particularly beneficial for people with autoimmune conditions.

Evidence-Based Insights

A 2014 clinical study found that individuals who supplemented with bovine colostrum experienced significantly fewer upper respiratory infections than a control group.

Research also shows that lactoferrin in colostrum inhibits the replication of certain viruses, offering protective effects during cold and flu season.

Colostrum may be particularly useful for individuals seeking to support their immune systems, including those recovering from illness.

2. Gut Health and Digestive Support

Your gut health affects everything from digestion to immunity and mood. Bovine colostrum supports a healthy gut lining and balances gut bacteria.

How It Works

Evidence-Based Insights

A study published in Nutrition revealed that colostrum reduced gut permeability in critically ill patients, providing significant gastrointestinal benefits.

Researchers have found that bovine colostrum can help mitigate inflammation in individuals with inflammatory bowel disease (IBD).

Colostrum's potential to support gut health may make it a useful option for those experiencing digestive discomfort. However, individual responses vary, and consultation with a healthcare provider is recommended.

3. Athletic Performance and Recovery

Bovine colostrum isn't just for those with health conditionsβ€”it's also a favorite among athletes. Its capacity to support tissue repair and minimize inflammation makes it an excellent aid for physical recovery.

How It Works

  • Muscle Recovery: Growth factors accelerate healing and repair after exercise-induced muscle damage.
  • Manages Inflammation: PRPs and lactoferrin ease post-exercise soreness, improving overall recovery time.
  • Stamina and Performance: Provides energy-sustaining nutrients that keep athletes performing at their best.

Evidence-Based Insights

In a double-blind study, athletes who took bovine colostrum supplements reported improved endurance and reduced muscle soreness compared to a placebo group.

IGF-1 in colostrum has been studied for its role in muscle growth and repair, which may benefit bodybuilders and endurance athletes. More research is needed to confirm these effects in larger populations.

4. Anti-Aging and Cellular Health

As we age, our bodies lose some ability to repair damaged tissues and fend off disease. Bovine colostrum may help slow down this process by supporting cellular health and reducing the effects of aging.

How It Works

  • Growth Factors: Promote collagen and elastin production, two key proteins that maintain skin elasticity and strength.
  • Antioxidants: Combat oxidative stress, a major contributor to aging and chronic disease.
  • Tissue Regeneration: Supports the repair of damaged cells, ensuring better recovery and maintenance of organs, skin, and other tissues.

Evidence-Based Insights

Studies suggest that IGF-1 in bovine colostrum stimulates the growth of new cells, enhancing wound healing and reducing the visible signs of aging.

Antioxidant-rich components in colostrum have been shown to neutralize free radicals, helping to protect against cell damage.

For individuals seeking to maintain youthful energy, skin health, and overall vitality, colostrum offers a natural way to combat age-related decline.

How to Use Bovine Colostrum

Bovine colostrum is versatile and available in several forms, making it easy to incorporate into your daily routine based on your lifestyle and health goals.

Forms of Bovine Colostrum

Bovine colostrum comes in several forms to suit different preferences and lifestyles:

  • Powder: This is the most versatile option. It can be mixed into water, smoothies, coffee, or other beverages. It is ideal for those who like to incorporate supplements into their meals.
  • Capsules: Convenient for those who prefer a pre-measured dose or need portability.
  • Liquid: Provides the highest potency but may require refrigeration and careful handling.

Dosage Recommendations

The correct dosage depends on your health goals and individual needs:

  • Immune Support: 0.5 to 1 gram daily for those with increased contact with infectious agents
  • Gut Health: Up to 20 grams daily is sometimes used in studies for digestive support, but individuals should consult a healthcare provider to determine the appropriate dose for their needs.
  • Athletic Recovery: 10–20 grams daily, divided into smaller doses before and after workouts.
  • Children: Generally, ΒΌ to Β½ of the adult dose (likely 14 mg to 4.5 g/kg/day). Always consult a healthcare provider for specific guidance.

Begin with a low dose to evaluate tolerance, then gradually increase as needed.

Tips for Maximizing Benefits

  • Timing: Take colostrum on an empty stomach for optimal absorption.
  • Pairing: Combine with probiotics to boost gut health or with vitamin C and zinc for enhanced immune support.
  • Storage: Keep in a cool, dry place to maintain potency, especially for powdered and capsule forms.

Scientific Evidence and Controversies

A growing body of scientific research supports the effectiveness of bovine colostrum, though some questions and misconceptions remain. Here's what the evidence tells us.

Clinical Research

A growing body of research supports the benefits of bovine colostrum:

  • A 2022 meta-analysis highlighted its ability to reduce respiratory infections and enhance immune resilience in children and adults.
  • Studies published in the Journal of Science and Medicine showed that athletes taking colostrum showed improved recovery times and less inflammation after intense exercise.
  • After regular colostrum supplementation, research on gut permeability showed significant improvement in patients with IBS and Crohn's disease.

While the evidence is promising, more large-scale, long-term studies are needed to confirm these effects across diverse populations.

Common Concerns

  1. Allergies and Dairy Sensitivities: People allergic to dairy proteins may react to colostrum. However, some individuals with lactose intolerance tolerate colostrum well due to its low lactose content. Always consult a doctor if unsure.
  2. Hormone Concerns: Growth factors in colostrum are naturally occurring and do not act like synthetic hormones. When consumed in recommended amounts, they're safe for most individuals.
  3. Ethical Sourcing: Many producers emphasize ethical sourcing practices, ensuring that calves receive adequate colostrum before the surplus is collected for human use. Look for products from trusted brands with transparent sourcing practices.

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Key Takeaways

  • Bovine colostrum is nutrient-dense, containing immunoglobulins, growth factors, and lactoferrin that benefit immunity, gut health, and recovery.
  • It may support the immune system by contributing to the body’s natural defenses and balancing immune responses.
  • It promotes gut health by repairing the gut lining, reducing inflammation, and fostering a healthy microbiome.
  • It has been studied for its potential to enhance athletic recovery, reduce muscle soreness, and support stamina.
  • It acts as an anti-aging tool, supporting tissue repair and protecting against oxidative stress.
  • Bovine colostrum is safe and versatile, with various forms and dosages to fit any health routine.
The information in this article is designed for educational purposes only and is not intended to be a substitute for informed medical advice or care. This information should not be used to diagnose or treat any health problems or illnesses without consulting a doctor. Consult with a health care practitioner before relying on any information in this article or on this website.

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BaΕ›kiewicz-HaΕ‚asa, M., Stachowska, E., ElΕΌbieta Grochans, Dominika Maciejewska-Markiewicz, BΓΌhner, L., Karolina Skonieczna-Ε»ydecka, & Maciej HaΕ‚asa. (2023). Moderate Dose Bovine Colostrum Supplementation in Prevention of Upper Respiratory Tract Infections in Medical University Students: A Randomized, Triple Blind, Placebo-Controlled Trial. Nutrients, 15(8), 1925–1925. https://doi.org/10.3390/nu15081925

Bertagna, B. (2024a, January 9). The Science Behind Mindful Eating: How It Impacts Digestion and Overall Health. Retrieved from Rupa Health website: https://www.rupahealth.com/post/the-science-behind-mindful-eating-how-it-impacts-digestion-and-overall-health

Bertagna, B. (2024b, January 15). Nurturing your gut, nurturing your mind: The key connection between gut health and improved mental well-being. Retrieved from Rupa Health website: https://www.rupahealth.com/post/nurturing-your-gut-nurturing-your-mind-the-key-connection-between-gut-health-and-improved-mental-well-being

Bertagna, B. (2024c, February 21). The Gut Microbiome: A Key Player in Chronic Disease Management. Retrieved from Rupa Health website: https://www.rupahealth.com/post/the-gut-microbiome-a-key-player-in-chronic-disease-management

Bertagna, B. (2024d, March 7). Fueling your gut: The best foods to restore gut health. Retrieved from Rupa Health website: https://www.rupahealth.com/post/fueling-your-gut-the-best-foods-to-restore-gut-health

Buckley, J. D., Abbott, M. J., Brinkworth, G. D., & Whyte, P. B. D. (2002). Bovine colostrum supplementation during endurance running training improves recovery, but not performance. Journal of Science and Medicine in Sport, 5(2), 65–79. https://doi.org/10.1016/s1440-2440(02)80028-7

Chae, A., Aitchison, A., Day, A. S., & Keenan, J. I. (2017). Bovine colostrum demonstrates anti-inflammatory and antibacterial activity in in vitro models of intestinal inflammation and infection. Journal of Functional Foods, 28, 293–298. https://doi.org/10.1016/j.jff.2016.11.016

Chandwe, K., & Kelly, P. (2021). Colostrum Therapy for Human Gastrointestinal Health and Disease. Nutrients, 13(6), 1956. https://doi.org/10.3390/nu13061956

Christie, J. (2023, February 14). How to Test Your Patients Amino Acid Levels. Retrieved from Rupa Health website: https://www.rupahealth.com/post/how-to-test-your-patients-amino-acid-levels

Christie, J. (2024, August 14). Optimizing Diagnostic Protocols for Cow's Milk Allergy in Infants With The Food Allergy IgE Panel. Retrieved from Rupa Health website: https://www.rupahealth.com/post/optimizing-diagnostic-protocols-for-cows-milk-allergy-in-infants-with-the-food-allergy-ige-panel

Cloyd, J. (2022, December 8). 3 Natural Treatments For Inflammatory Bowel Disease. Retrieved from Rupa Health website: https://www.rupahealth.com/post/inflammatory-bowel-disease-ibd-treatments-for-flares-and-remission

Cloyd, J. (2023a, February 28). How to test for lactose intolerance. Retrieved from Rupa Health website: https://www.rupahealth.com/post/how-to-test-for-lactose-intolerance

Cloyd, J. (2023b, March 29). An Integrative Medicine Guide to Ulcerative Colitis. Retrieved from Rupa Health website: https://www.rupahealth.com/post/an-integrative-medicine-guide-to-ulcerative-colitis

Cloyd, J. (2023c, April 19). What's the Difference Between Prebiotics vs. Probiotics vs. Postbiotics? Retrieved from Rupa Health website: https://www.rupahealth.com/post/whats-the-difference-between-prebiotics-vs-probiotics-vs-postbiotics

Cloyd, J. (2023d, May 23). A Comprehensive Review of IBS-D: Differential Diagnosis, Specialty Testing, and Integrative Treatment Options. Retrieved from Rupa Health website: https://www.rupahealth.com/post/a-comprehensive-review-of-ibs-d-differential-diagnosis-specialty-testing-and-integrative-treatment-options

Cloyd, J. (2023e, June 8). A Functional Medicine IBS-D Protocol: Testing, Differential Diagnosis, and Treatment. Retrieved from Rupa Health website: https://www.rupahealth.com/post/a-functional-medicine-ibs-d-protocol-testing-nutrition-and-supplements

Cloyd, J. (2023f, July 4). Top Micronutrients for Skin Health and How to Test for Them. Retrieved from Rupa Health website: https://www.rupahealth.com/post/micronutrients-for-skin-health

Cloyd, J. (2023g, November 29). The Hidden Impact of Our Gut: How Intestinal Permeability Influences a Range of Diseases. Retrieved from Rupa Health website: https://www.rupahealth.com/post/the-hidden-impact-of-our-gut-how-intestinal-permeability-influences-a-range-of-diseases

Cloyd, K. (2023h, December 20). Interpreting Oxidative Stress Markers. Retrieved from Rupa Health website: https://www.rupahealth.com/post/interpreting-oxidative-stress-markers

Daglis, S. (2024, March 19). What Are the Benefits of Collagen Peptides? Retrieved from Rupa Health website: https://www.rupahealth.com/post/what-are-the-benefits-of-collagen-peptides

DePorto, T. (2023, January 11). Zinc 101. Retrieved from Rupa Health website: https://www.rupahealth.com/post/zinc

Dinarello, C. A. (2000). Proinflammatory Cytokines. Chest, 118(2), 503–508. https://doi.org/10.1378/chest.118.2.503

Dziewiecka, H., Buttar, H. S., Kasperska, A., Ostapiuk-Karolczuk, J., Domagalska, M., CichoΕ„, J., & SkarpaΕ„ska-Stejnborn, A. (2022). A Systematic Review of the Influence of Bovine Colostrum Supplementation on Leaky Gut Syndrome in Athletes: Diagnostic Biomarkers and Future Directions. Nutrients, 14(12), 2512. https://doi.org/10.3390/nu14122512

Eslamian, G., Ardehali, S. H., Baghestani, A.-R., & Vahdat Shariatpanahi, Z. (2019). Effects of early enteral bovine colostrum supplementation on intestinal permeability in critically ill patients: A randomized, double-blind, placebo-controlled study. Nutrition, 60, 106–111. https://doi.org/10.1016/j.nut.2018.10.013

Forthal, D. N. (2014). Functions of Antibodies. Microbiology Spectrum, 2(4), 1–17. https://doi.org/10.1128/microbiolspec.aid-0019-2014

Gonzalez-Quintela, A., Alende, R., Gude, F., Campos, J., Rey, J., Meijide, L. M., … Vidal, C. (2007). Serum levels of immunoglobulins (IgG, IgA, IgM) in a general adult population and their relationship with alcohol consumption, smoking and common metabolic abnormalities. Clinical & Experimental Immunology, 151(1), 42–50. https://doi.org/10.1111/j.1365-2249.2007.03545.x

Greenan, S. (2021, November 17). The 8 Most Common Signs Of A Food Sensitivity. Retrieved from Rupa Health website: https://www.rupahealth.com/post/a-functional-medicine-approach-to-food-sensitivities-testing-and-treatment

Guberti, M., Botti, S., Capuzzo, M. T., Nardozi, S., Fusco, A., Cera, A., … De Marinis, M. G. (2021). Bovine Colostrum Applications in Sick and Healthy People: A Systematic Review. Nutrients, 13(7), 2194. https://doi.org/10.3390/nu13072194

Harmsen, M. C., Swart, P. J., Bethune, M.-P. . d., Pauwels, R., Clercq, E. D., The, T. B., & Meijer, D. K. F. (1995). Antiviral Effects of Plasma and Milk Proteins: Lactoferrin Shows Potent Activity against Both Human Immunodeficiency Virus and Human Cytomegalovirus Replication In Vitro. Journal of Infectious Diseases, 172(2), 380–388. https://doi.org/10.1093/infdis/172.2.380

Immunoglobulin A | Rupa Health. (2020). Retrieved from Rupa Health website: https://www.rupahealth.com/biomarkers/total-iga

Immunoglobulin G. (n.d.). Retrieved from Rupa Health website: https://www.rupahealth.com/biomarkers/total-igg

Immunoglobulin M | Rupa Health. (2020). Retrieved from Rupa Health website: https://www.rupahealth.com/biomarkers/total-igm

Insulin-Like Growth Factor 1 | Rupa Health. (2020). Retrieved from Rupa Health website: https://www.rupahealth.com/biomarkers/igf-1

Jagirdar, J., Begin, R., Dufresne, A., Goswami, S., Lee, T. C., & Rom, W. N. (1996). Transforming growth factor-beta (TGF-beta) in silicosis. American Journal of Respiratory and Critical Care Medicine, 154(4), 1076–1081. https://doi.org/10.1164/ajrccm.154.4.8887610

Jones, A. W., Cameron, S. J. S., Thatcher, R., Beecroft, M. S., Mur, L. A. J., & Davison, G. (2014). Effects of bovine colostrum supplementation on upper respiratory illness in active males. Brain, Behavior, and Immunity, 39, 194–203. https://doi.org/10.1016/j.bbi.2013.10.032

Khakham, C. (2023, May 15). Boosting Your Patient's Immunity Through Gut Health: Testing, Nutrition and Supplements. Retrieved from Rupa Health website: https://www.rupahealth.com/post/the-gut-microbiome-and-immunity-how-integrative-approaches-can-boost-immune-function

Kim, H., Kim, D. E., Han, G., Lim, N. R., Kim, E. H., Jang, Y., … Yang, Y. (2021). Harnessing the Natural Healing Power of Colostrum: Bovine Milk‐derived Extracellular Vesicles from Colostrum Facilitating the Transition from Inflammation to Tissue Regeneration for Accelerating Cutaneous Wound Healing. Advanced Healthcare Materials, 2102027. https://doi.org/10.1002/adhm.202102027

Lactoferrin. (n.d.). Retrieved from Rupa Health website: https://www.rupahealth.com/biomarkers/lactoferrin

Levay, P. F., & Viljoen, M. (1995). Lactoferrin: a general review. Haematologica, 80(3), 252–267.

Liu, H. C., Chen, W. L., & Mao, S. J. T. (2007). Antioxidant Nature of Bovine Milk Ξ²-Lactoglobulin. Journal of Dairy Science, 90(2), 547–555. https://doi.org/10.3168/jds.s0022-0302(07)71538-2

Maciej HaΕ‚asa, BaΕ›kiewicz-HaΕ‚asa, M., Dominika JamioΕ‚-Milc, Dominika Maciejewska-Markiewicz, & Karolina Skonieczna-Ε»ydecka. (2022). Bovine colostrum supplementation in prevention of upper respiratory tract infections – Systematic review, meta-analysis and meta-regression of randomized controlled trials. Journal of Functional Foods, 99, 105316–105316. https://doi.org/10.1016/j.jff.2022.105316

Maholy, N. (2023, May 10). A Functional Medicine Immune Support Protocol. Retrieved from Rupa Health website: https://www.rupahealth.com/post/a-functional-medicine-immune-support-protocol

Martino, R., Giralt, S., Caballero, M. D., Mackinnon, S., Corradini, P., Fernandez-Aviles, F., … Sierra, J. (2003). Allogeneic hematopoietic stem cell transplantation with reduced-intensity conditioning in acute lymphoblastic leukemia: a feasibility study. Haematologica, 88(5), 555–560. https://doi.org/10.3324/%x

McGrath, B. A., Fox, P. F., McSweeney, P. L. H., & Kelly, A. L. (2015). Composition and properties of bovine colostrum: a review. Dairy Science & Technology, 96(2), 133–158. https://doi.org/10.1007/s13594-015-0258-x

Mero, A., NykΓ€nen, T., KeinΓ€nen, O., Knuutinen, J., Lahti, K., Alen, M., … LeppΓ€luoto, J. (2005). Protein metabolism and strength performance after bovine colostrum supplementation. Amino Acids, 28(3), 327–335. https://doi.org/10.1007/s00726-005-0179-8

Mix, E., Goertsches, R., & Zett, U. K. (2006). Immunoglobulinsβ€”Basic considerations. Journal of Neurology, 253(5), v9–v17. https://doi.org/10.1007/s00415-006-5002-2

Morrison, S. A., Cheung, S. S., & Cotter, J. D. (2014). Bovine colostrum, training status, and gastrointestinal permeability during exercise in the heat: a placebo-controlled double-blind study. Applied Physiology, Nutrition, and Metabolism, 39(9), 1070–1082. https://doi.org/10.1139/apnm-2013-0583

Playford, R. J., & Weiser, M. J. (2021). Bovine Colostrum: Its Constituents and Uses. Nutrients, 13(1). https://doi.org/10.3390/nu13010265

Preston, J. (2022, December 20). How To Build Natural Immunity During A Bad Flu Season. Retrieved from Rupa Health website: https://www.rupahealth.com/post/building-immunity-during-flu-season

Preston, J. (2023, June 21). An integrative medicine approach to food allergies: Specialty testing and treatment options. Retrieved from Rupa Health website: https://www.rupahealth.com/post/an-integrative-medicine-approach-to-food-allergies-specialty-testing-cross-contamination-and-treatment-options

Ringe, D., & Petsko, G. A. (2008). BIOCHEMISTRY: How Enzymes Work. Science, 320(5882), 1428–1429. https://doi.org/10.1126/science.1159747

Shing, C. M. (2006). The influence of bovine colostrum supplementation on exercise performance in highly trained cyclists. British Journal of Sports Medicine, 40(9), 797–801. https://doi.org/10.1136/bjsm.2006.027946

Shing, C. M., Hunter, D. C., & Stevenson, L. M. (2009). Bovine Colostrum Supplementation and Exercise Performance. Sports Medicine, 39(12), 1033–1054. https://doi.org/10.2165/11317860-000000000-00000

Stanford, J. (2024, May 23). Growth Hormone: The Key to Development, Health, and Longevity. Retrieved from Rupa Health website: https://www.rupahealth.com/post/growth-hormone

Stelwagen, K., Carpenter, E., Haigh, B., Hodgkinson, A., & Wheeler, T. T. (2009). Immune components of bovine colostrum and milk1. Journal of Animal Science, 87(suppl_13), 3–9. https://doi.org/10.2527/jas.2008-1377

Sweetnich, J. (2023a, February 17). 6 Health Benefits of Prebiotics. Retrieved from Rupa Health website: https://www.rupahealth.com/post/6-health-benefits-of-prebiotics

Sweetnich, J. (2023b, May 9). How to make sure your patients are getting enough vitamin C in their diet: Understanding testing, RDAs, and the benefits of supplementation. Retrieved from Rupa Health website: https://www.rupahealth.com/post/vitamin-c-101

Sydney, A. C. N., Ikeda, I. K., de Oliveira Ribeiro, M. C., Sydney, E. B., de Carvalho Neto, D. P., Karp, S. G., … Soccol, C. R. (2022, January 1). 18 - Colostrum new insights: products and processes (A. K. Rai, S. P. Singh, A. Pandey, C. Larroche, & C. R. Soccol, Eds.). Retrieved from ScienceDirect website: https://www.sciencedirect.com/science/article/pii/B9780128235065000035

Transforming Growth Factor Beta 1 | Rupa Health. (2020). Retrieved December 7, 2024, from Rupa Health website: https://www.rupahealth.com/biomarkers/transforming-growth-factor-beta-1

Vitali, A. (2015). Proline-Rich Peptides: Multifunctional Bioactive Molecules as New...: Ingenta Connect. Retrieved December 7, 2024, from Ingentaconnect.com website: https://www.ingentaconnect.com/content/ben/cpps/2015/00000016/00000002/art00007

Vojdani, A. (2022, April 25). The Importance of Detecting Autoimmune Diseases During Preclinical and Clinical Stage. Retrieved from Rupa Health website: https://www.rupahealth.com/post/the-importance-of-detecting-autoimmune-diseases-during-preclinical-and-clinical-stage

Weinberg, J. (2022, April 14). 4 lifestyle changes that help manage Crohn’s disease. Retrieved from Rupa Health website: https://www.rupahealth.com/post/a-functional-medicine-approach-to-crohns-disease

Wilson, D., Evans, M., Weaver, E., Shaw, A. L., & Klein, G. L. (2013). Evaluation of Serum-Derived Bovine Immunoglobulin Protein Isolate in Subjects with Diarrhea-Predominant Irritable Bowel Syndrome. Clinical Medicine Insights: Gastroenterology, 6, CGast.S13200. https://doi.org/10.4137/cgast.s13200

Yoshimura, H. (2023a, April 18). Preventative Treatment Options for Recurrent Geriatric Infections with Integrative Medicine. Retrieved from Rupa Health website: https://www.rupahealth.com/post/preventative-treatment-for-recurrent-geriatric-infections-with-integrative-medicine

Yoshimura, H. (2023b, October 23). Are Supplements Really Necessary?: Pros, Cons, and How Testing Can Help. Retrieved from Rupa Health website: https://www.rupahealth.com/post/are-supplements-really-necessary-pros-cons-and-how-testing-can-help

Yoshimura, H. (2023c, November 2). From Zinc to Magnesium: Micronutrients that Supercharge Gut Healing. Retrieved from Rupa Health website: https://www.rupahealth.com/post/from-zinc-to-magnesium-micronutrients-that-supercharge-gut-healing

Yoshimura, H. (2023d, November 7). The remarkable power of exercise on our health: A comprehensive overview. Retrieved from Rupa Health website: https://www.rupahealth.com/post/the-remarkable-power-of-exercise-on-our-health-a-comprehensive-overview

Yoshimura, H. (2024, January 5). Respiratory Health in Winter: Functional Medicine Approaches to Preventing Colds and Flu. Retrieved from Rupa Health website: https://www.rupahealth.com/post/respiratory-health-in-winter-functional-medicine-approaches-to-preventing-colds-and-flu

ZabΕ‚ocka, A., Siednienko, J., Mitkiewicz, M., Gorczyca, W. A., Lisowski, J., & Janusz, M. (2009). Proline-rich polypeptide complex (PRP) regulates secretion of inflammatory mediators by its effect on NF-ΞΊB activity. Biomedicine & Pharmacotherapy, 64(1), 16–20. https://doi.org/10.1016/j.biopha.2009.01.009

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The Journal of Pediatrics
Peer Reviewed Journal
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CDC
Government Authority
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Office of Dietary Supplements
Government Authority
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National Heart Lung and Blood Institute
Government Authority
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National Institutes of Health
Government Authority
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Clinical Infectious Diseases
Peer Reviewed Journal
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Brain
Peer Reviewed Journal
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The Journal of Rheumatology
Peer Reviewed Journal
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Journal of the National Cancer Institute (JNCI)
Peer Reviewed Journal
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Journal of Cardiovascular Magnetic Resonance
Peer Reviewed Journal
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Hepatology
Peer Reviewed Journal
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The American Journal of Clinical Nutrition
Peer Reviewed Journal
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The Journal of Bone and Joint Surgery
Peer Reviewed Journal
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Kidney International
Peer Reviewed Journal
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The Journal of Allergy and Clinical Immunology
Peer Reviewed Journal
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Annals of Surgery
Peer Reviewed Journal
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Chest
Peer Reviewed Journal
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The Journal of Neurology, Neurosurgery & Psychiatry
Peer Reviewed Journal
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Blood
Peer Reviewed Journal
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Gastroenterology
Peer Reviewed Journal
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The American Journal of Respiratory and Critical Care Medicine
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The American Journal of Psychiatry
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Diabetes Care
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The Journal of the American College of Cardiology (JACC)
Peer Reviewed Journal
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The Journal of Clinical Oncology (JCO)
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Journal of Clinical Investigation (JCI)
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Circulation
Peer Reviewed Journal
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JAMA Internal Medicine
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PLOS Medicine
Peer Reviewed Journal
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Annals of Internal Medicine
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Nature Medicine
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The BMJ (British Medical Journal)
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The Lancet
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Journal of the American Medical Association (JAMA)
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Pubmed
Comprehensive biomedical database
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Harvard
Educational/Medical Institution
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Cleveland Clinic
Educational/Medical Institution
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Mayo Clinic
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The New England Journal of Medicine (NEJM)
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Johns Hopkins
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