Medication Fact Sheets
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December 23, 2024

Bisacodyl: How It Works and When to Use It

Written By
Medically Reviewed by
Dr. Sarah Daglis ND
Updated On
January 7, 2025

Dealing with occasional constipation can be frustrating and uncomfortable. For many people, over-the-counter laxatives like bisacodyl offer a simple solution. Bisacodyl is a commonly used medication that helps stimulate bowel movements, making it easier to relieve constipation. 

This article will explore bisacodyl, how it works, when it's used, and tips for taking it safely. Whether you're looking for information for yourself or helping a loved one, this guide will provide the answers you need.

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What is Bisacodyl?

Bisacodyl is a stimulant laxative commonly used to help relieve occasional constipation. Constipation happens when it becomes hard to pass stool, and this can leave you feeling bloated or uncomfortable. 

Bisacodyl encourages your body to have a bowel movement, helping things move along more smoothly.

How It Works

Bisacodyl stimulates the muscles in the intestines, the long tubes in the digestive system that carry food and waste. When these muscles contract, they help push stool through the system. 

Bisacodyl also helps the intestines release more water into the stool, making it softer and easier to pass. Increased muscle activity and softened stool make bisacodyl a practical option for occasional constipation relief.

Forms Available

Bisacodyl comes in different forms, so you can choose what works best. The most common forms are:

  • Tablets: These are taken by mouth and usually start working within 6 to 12 hours.
  • Suppositories: These are inserted into the rectum and work faster, often within 15 to 60 minutes.
  • Enemas: These liquids inserted into the rectum provide quick relief, typically within 5 to 20 minutes.

Each form has its benefits, so your choice may depend on how quickly you need relief or what feels most comfortable for you to use. Individual experiences may vary. Always follow the instructions on the package or check with your healthcare provider to use bisacodyl safely.

Uses and Benefits of Bisacodyl

Bisacodyl is widely used to help people manage constipation and prepare for specific medical procedures. Understanding when and why bisacodyl is used can help determine if it's the right choice for your needs.

Common Uses

Bisacodyl serves distinct purposes depending on the situation, ranging from occasional relief to preparation for medical procedures.

Temporary Relief of Occasional Constipation

Bisacodyl is most commonly used to relieve occasional constipation, which can happen for many reasons, such as changes in diet, dehydration, or reduced physical activity. 

It helps by making stools easier to pass and restoring regular bowel movements.

Pre-Surgical or Diagnostic Bowel Cleansing

The intestines must be emptied before specific medical procedures, such as a colonoscopy or surgery. Bisacodyl is often used as part of a bowel cleansing routine to ensure the colon is clear of stool.

Effectiveness

Research supports the effectiveness of bisacodyl for relieving constipation and preparing the bowel for medical procedures.

Studies have shown that bisacodyl is highly effective at promoting bowel movements. Most people experience relief within 6 to 12 hours when using tablets or within an hour when using suppositories or enemas, making it a widely used option for quick relief.

While bisacodyl is effective, it is essential to use it as directed and avoid overuse, as overuse can lead to side effects or dependency. If you're unsure whether bisacodyl is the right option for you, it's important to consult a healthcare professional.

Proper Dosage and Administration

Using bisacodyl correctly is essential for effective relief while minimizing the risk of side effects. This section will guide you through the recommended dosages, how to use different forms of bisacodyl, and the necessary precautions to take.

Recommended Dosage

The correct dose of bisacodyl depends on the form you're using and your age. The following are general recommendations, but be sure to follow the instructions on the package and consult a healthcare provider for tailored advice.

Bisacodyl Tablets (Oral)

  • Adults and Children Over 12: 5 to 10 mg once daily.
  • Children 6 to 12 Years: 5 mg once daily.
  • Children Under 6: Not recommended unless directed by a doctor.

Bisacodyl Suppositories (Rectal)

  • Adults and Children Over 10: 10 mg once daily.
  • Children 4 to 10 Years: 5 mg once daily.

Bisacodyl Enemas (Rectal Liquid)

  • Adults and Children Over 12: 10 mg once daily.
  • Children 12 Years and Under: Do not use.

Instructions for Use

Here are guidelines for how to use Bisacodyl:

How to Take Bisacodyl Tablets

  • Swallow the tablets whole with a full glass of water. Do not crush, chew, or break them, as this can irritate the stomach.
  • Take tablets on an empty stomach or before bedtime for overnight relief (they usually work within 6 to 12 hours).
  • Avoid taking the tablets with milk, antacids, or other medications, as these may interfere with how bisacodyl works.

How to Use Bisacodyl Suppositories

  • Wash your hands before and after use.
  • Remove the wrapper from the suppository.
  • Gently insert the suppository into the rectum, with the pointed end first, as far as it comfortably goes.
  • Remain lying down for a few minutes to keep the suppository in place. It typically works within 15 to 60 minutes.

How to Use Bisacodyl Enemas

  • Shake the bottle well and remove the protective cap.
  • Carefully insert the applicator tip into the rectum, pointing it slightly upward.
  • Squeeze the bottle to release the liquid and remove it while continuing to apply pressure.
  • Stay in a comfortable position for a few minutes until you feel the urge to have a bowel movement, which usually occurs within a few minutes.

Potential Side Effects and Risks

Like any medication, bisacodyl can cause side effects, mainly if it's not used as directed. While many people use it without issues, knowing what to watch for and who should avoid it is crucial.

Common Side Effects

Most side effects from bisacodyl are mild and go away on their own. These may include:

  • Abdominal Cramping: You may feel stomach discomfort or cramping as your intestines are stimulated.
  • Diarrhea: Sometimes, stools may become too loose, leading to diarrhea.
  • Nausea or Discomfort: Some people experience mild nausea or a bloated feeling after taking bisacodyl.

To reduce these side effects, avoid taking more than the recommended dose and drink plenty of water while using the medication.

Serious Side Effects

Though rare, serious side effects can occur, especially with frequent or improper use of bisacodyl. These include:

  • Electrolyte Imbalance: Frequent diarrhea from overuse can result in the loss of essential minerals like potassium and sodium. This imbalance can cause fatigue, muscle weakness, or irregular heart rhythms.
  • Dependency: Using bisacodyl too often can make your intestines "lazy," meaning they may stop working correctly without the medication. This is called laxative dependency.
  • Severe Dehydration: Excessive fluid loss from diarrhea can lead to dehydration, which may cause dizziness, dry mouth, or fainting.

Always use as directed. If you experience any of these severe side effects, stop using bisacodyl and contact a healthcare provider immediately.

Who Should Avoid It?

Bisacodyl is not safe for everyone. Certain conditions or situations may increase the risks associated with its use:

  • Pregnancy and Breastfeeding: Pregnant or nursing individuals should consult a healthcare provider before using bisacodyl. It's generally considered safe for occasional use, but medical advice is essential.
  • Underlying Medical Conditions: Avoid bisacodyl if you have severe digestive issues, such as intestinal obstruction, appendicitis, or inflammatory bowel disease (IBD), as it may worsen these conditions.
  • Children Under 6 Years: Bisacodyl should not be used in young children unless directed by a doctor.
  • Known Allergies: Avoid using bisacodyl if you are allergic to bisacodyl or its ingredients.
  • Severe Abdominal Pain or Nausea: Do not use bisacodyl if you have unexplained or persistent abdominal pain, nausea, or vomiting. These symptoms could reflect a more severe condition requiring medical attention.

When to See a Doctor

If you experience severe side effects, such as persistent diarrhea, dehydration, or signs of an electrolyte imbalance (e.g., extreme fatigue or muscle cramping), contact your doctor right away. 

Additionally, if constipation lasts longer than a week despite using bisacodyl, you may need a different treatment plan.

Bisacodyl vs. Other Laxatives

When choosing a laxative, it's important to understand how different options work and which one might best fit your situation.

Comparison with Alternatives

Here's how bisacodyl stacks up against other common laxatives:

Polyethylene Glycol (PEG)

  • How It Works: PEG is an osmotic laxative, meaning it draws water into the intestines to soften stool and make it easier to pass.
  • Best For: Chronic constipation or cases where stool softening is needed over time. It works gradually, typically within 2 to 4 days.
  • Comparison: Unlike bisacodyl, PEG is gentler and better suited for long-term use. However, bisacodyl works much faster (within hours), making it ideal for immediate relief.

Senna

  • How It Works: Senna is another stimulant laxative that, like bisacodyl, stimulates the intestines to move stool through the digestive system.
  • Best For: Occasional constipation, especially for those who prefer a plant-based option (senna is derived from a natural herb).
  • Comparison: Senna and bisacodyl work similarly and provide quick relief. However, due to its predictable action, bisacodyl is commonly used for medical procedures (e.g., bowel prep).

Lactulose

  • How It Works: Lactulose is a sugar-based osmotic laxative that helps draw water into the stool and is commonly used for chronic constipation.
  • Best For: People with long-term constipation, including those with liver conditions like hepatic encephalopathy (a specific use case). It typically works within 24 to 48 hours.
  • Comparison: While lactulose is slower and better for ongoing constipation management, bisacodyl provides faster relief and is more suited for occasional or short-term use.

Fiber Supplements

  • How They Work: Supplements like psyllium are bulk-forming laxatives that add fiber to the stool, making it larger and easier to pass.
  • Best For: Maintaining regular bowel movements over the long term.
  • Comparison: Fiber supplements work gradually, while bisacodyl provides immediate results. Fiber is a good preventive measure, but bisacodyl is helpful when quick action is needed.

When to Choose Bisacodyl

Bisacodyl is particularly useful in the following scenarios:

  • Quick relief
  • Bowel prep for medical procedures
  • Occasional constipation

However, using bisacodyl only as directed and for short-term relief is important. For chronic constipation, slower-acting laxatives like PEG or lactulose may be better options. 

Always consult a healthcare provider if you're unsure which laxative is right for you.

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Key Takeaways

  • Bisacodyl is a stimulant laxative that helps relieve occasional constipation by stimulating intestinal muscles and softening stool for easier passage.
  • It is available in oral tablets, rectal suppositories, and enemas, with varying onset times ranging from minutes to hours, depending on the form used.
  • Common uses include temporary constipation relief and bowel cleansing before medical procedures like colonoscopies or surgeries.
  • Side effects like cramping or diarrhea are typically mild but can become severe with misuse, highlighting the importance of using bisacodyl only as directed.
The information in this article is designed for educational purposes only and is not intended to be a substitute for informed medical advice or care. This information should not be used to diagnose or treat any health problems or illnesses without consulting a doctor. Consult with a health care practitioner before relying on any information in this article or on this website.

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